Cytochemical studies of the effects of activin on gonadotropin-releasing hormone (GnRH) binding by pituitary gonadotropes and growth hormone cells

Journal of Histochemistry and Cytochemistry

Volumn 45, Issue 12, 1997, Pages 1603-1610

  Childs, Gwen V ^a   Unabia, Geda ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

Author keywords

Activin; Anterior pituitary; Follicle stimulating hormone; Gonadotrope; Gonadotropin releasing hormone receptors; Growth hormone; Luteinizing hormone; Rat

Indexed keywords

ACTIVIN; ESTRADIOL; FOLLITROPIN; GONADORELIN; GONADORELIN RECEPTOR; GROWTH HORMONE; LUTEINIZING HORMONE;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; CYTOCHEMISTRY; DIESTRUS; FEMALE; GONADOTROPIN SECRETING CELL; HYPOPHYSIS; NONHUMAN; PRIORITY JOURNAL; PROESTRUS; RAT;

ANIMALIA;

EID: 0030668601     PISSN: 00221554     EISSN: None     Source Type: Journal    
DOI: 10.1177/002215549704501203     Document Type: Article

References (41)

1. Besecke LM, Guendner MJ, Schneyer AL, Bauer-Dantoin AC, Jameson JL, Weiss J (1996) Gonadotropin-releasing hormone regulates follicle stimulating hormone-β gene expression through an activin/follistatin autocrine or paracrine loop. Endocrinology 137:3667-3673
2. Bilezikjian LM, Blount AL, Campen CA, Gonzalez-Manchon C, Vale W (1991) Activin-A inhibits proopiomelanocortin messenger RNA accumulation and adrenocorticotropin secretion in AtT20 cells. Mol Endocrinol 5:1389-1395
3. Bilezikjian LM, Corrigan AZ, Vale W (1990) Activin-A modulates growth hormone secretion from cultures of rat anterior pituitary cells. Endocrinology 126:2369-2376
4. Bilezikjian LM, Corrigan AX, Vale WW (1993) Activin-B, inhibin-B and follistatin as autocrine/paracrine factors of the rat anterior pituitary. In Burger HG, ed. Challenges in Endocrinology and Modern Medicine. Proceedings II international symposium on inhibin and inhibin-related proteins, 1-19.
5. Billestrup N, Gonzalez-Manchon C, Potter E, Vale W (1990) Inhibition of somatotroph growth and growth hormone biosynthesis by activin in vitro. Mol Endocrinol 4:356-362
6. Braden TD, Conn PM (1990) Activin A stimulates the synthesis of gonadotropin-releasing hormone receptors. Endocrinology 130: 2101-1115
7. Braden TD, Conn PM (1991) The 1990 James A.F. Stevenson Memorial Lecture. Gonadotropin-releasing hormone and its actions. Can J Physiol Pharmacol 69:445-458
8. Carrol RS, Corrigan AZ, Gharib SD, Vale W, Chin WW (1988) Inhibin, activin and follistatin: regulation of follicle stimulating hormone messenger ribonucleic acid levels. Mol Endocrinol 3:1969-1976
9. Childs GV, Hyde C, Naor Z (1983c) Morphometric analysis of thyrotropes in developing and cycling female rats: studies of intact pituitaries and cell fractions separated by centrifugal elutriation. Endocrinology 113:1601-1607
10. Childs GV, Miller BT, Miller WL (1997) Differential effects of inhibin on gonadotropin stores and gonadotropin releasing hormone binding to pituitary cells from cycling female rats. Endocrinology 138:1577-1584
11. Childs GV, Naor Z, Hazum E, Tibolt R, Westlund KM, Hancock MB (1983a) Localization of biotinylated gonadotropin releasing hormone on pituitary monolayer cells with avidin-biotin peroxidase complexes. J Histochem Cytochem 31:1422-1425
12. Childs GV, Naor Z, Hazum E, Tibolt R, Westlund KN, Hancock MB (1983b) Cytochemical characterization of pituitary target cells for biotinylated gonadotropin releasing hormone. Peptides 4:549-555
13. Childs GV, Unabia G, Lloyd J (1991a) Recruitment and maturation of small subsets of luteinizing hormone (LH) gonadotropes during the estrous cycle. Endocrinology 130:335-345
14. Childs GV, Unabia G, Lloyd JM (1991b) Maturation of FSH gonadotropes during the rat estrous cycle. Endocrinology 131:29-36
15. Childs GV, Unabia G, Miller BT (1994b) Cytochemical detection of GnRH binding sites on rat pituitary cells with LH, FSH and GH antigens during diestrous upregulation. Endocrinology 134: 1943-1956
16. Childs GV, Unabia G, Rougeau D (1994a) Cells that express luteinizing hormone (LH) and follicle stimulating hormone (FSH) beta (β) subunit mRNAs during the estrous cycle: the major contributors contain LHβ, FSHβ and/or growth hormone. Endocrinology 134:990-998
17. Childs GV, Unabia G, Tibolt R, Lloyd JM (1987) Cytological factors that support non-parallel secretion of LH and FSH during the estrous cycle. Endocrinology 121:1801-1813
18. Childs GV, Unabia G, Weirman ME, Gharib SD, Chin WW (1990) Castration induces time-dependent changes in the FSHβ-mRNA-containing gonadotrope cell population. Endocrinology 126: 2205-2213
19. Clayton RN, Solano AR, Garcia-Vela A, Dufau ML, Cart KJ (1980) Regulation of pituitary receptors for gonadotropin-releasing hormone during the rat estrous cycle. Endocrinology 107: 699-706
20. Conn PM, Janovic JA, Stanislaus D, Kuphal D, Jennes L (1995) Molecular and cellular bases of gonadotropin releasing hormone action in the pituitary and central nervous system. Vit Horm 50:152-201
21. De Kretser DM, Robertson DM (1989) The isolation and physiology of inhibin and related proteins. Biol Reprod 40:33-37
22. Fernandez-Vazquez G, Albarrancin CT, Kaiser UB, Chin WW (1995) Transcriptional activation of the gonadotropin-releasing hormone receptor (GnRHR) gene by activin A in alpha T3-1 cells. Proc Endocrine Soc P2-36
23. Funabashi T, Brooks PJ, Weesner GD, Pfaff DW (1994) Luteinizing hormone-releasing hormone receptor messenger ribonucleic acid expression in the rat pituitary during lactation and the estrous cycle. J Neuroendocrinol 6:261-266
24. Halvorson LM, Weiss J, Bauer-Dantoin AC, Jameson JL (1994) Dynamic regulation of pituitary follistatin messenger ribonucleic acids during the rat estrous cycle. Endocrinology 134:1247-1253
25. Katayama T, Shiota K, Takahashi M (1990) Activin A increases the number of follicle-stimulating hormone cells in anterior pituitary cultures. Mol Cell Endocrinol 69:179-185
26. Kingsley DM (1994) The TGF-β superfamily: new members, new receptors, and new genetic tests of function in different organisms. Genes Dev 8:133-146
27. Kitaoka M, Kojima I, Ogata E (1988) Activin-A: modulator of multiple types of anterior pituitary cells. Biochem Biophys Res Commun 157:48-54
28. Knight PG (1996) Roles of inhibins, activins and follistatin in the female reproductive system. Frontiers Neuroendocrinol 17:476-509
29. Lee BL, Unabia G, Childs G (1993) Expression of follistatin mRNA in somatotropes and mammotropes early in the estrous cycle. J Histochem Cytochem 41:955-960
30. Ling N, Ying S-Y, Ueno N, Shimasaki S, Esch F, Hotta N, Guillemin R (1986) Pituitary FSH is released by a heterodimer of the β-sub-units from the two forms of inhibin. Nature 321:779-782
31. Lloyd JM, Childs GV (1988) Changes in the number of GnRH-receptive cells during the rat estrous cycle: biphasic effects of estradiol. Neuroendocrinology 48:138-146
32. Park KR, Saxena BB, Grandy HM (1976) Specific binding of LH-RH to the anterior pituitary gland during the estrous cycle in the rat. Acta Endocrinol 82:62-70
33. Savoy-Moore RT, Schwartz NB, Duncan JA, Marshall JC (1980) Pituitary gonadotropin releasing hormone receptors during the rat estrous cycle. Science 209:942-944
34. Stouffer R, Woodruff T, Dahl K, Hess D, Mather J, Molkness T (1993) Human recombinant activin A alters pituitary luteinizing hormone and follicle-stimulating hormone secretion, follicle development and steroidogenesis during the menstrual cycle in rhesus monkeys. J Clin Endocrinol Metab 77:241-248
35. Struthers SR, Gaddy-Kurten D, Vale WW (1992) Activin inhibits binding of transcription factor Pir-1 to the growth hormone promotor. Proc Natl Acad Sci USA 89:11451-11455
36. Tilemans D, Andries M, Denef C (1992) Luteinizing hormone-releasing hormone and neuropeptide Y influence DNA replication in three anterior pituitary cell types. Evidence for mediation by growth factors released from gonadotropes. Endocrinology 130: 882-894
37. Vale W, Hsueh A, Rivier C, Yu J (1990) The inhibin/activin family of hormones and growth factors. In Sporn M, Roberts A, eds. Peptide Growth Factors and Their Receptors. Berlin, Springer-Verlag, 211-248
38. Vale W, Rivier C, Hsueh A, Campen C, Meunier H, Bicsak T, Vaughan J, Corrigan A, Bardin W, Sawchenko P, Petraglia F, Yu J, Plotsky P, Spiess J, Rivier J (1988) Chemical and biological characterization of the inhibin family of protein hormones. Rec Prog Horm Res 44:1-34
39. Vale W, Rivier J, Vaughan J, McClintock R, Corrigan A, Woo W, Karr D, Spiess J (1986) Purification and characterization of an FSH-releasing protein from porcine ovarian follicular fluid. Nature 321:776-779
40. Van Bael A, Proesmans M, Tilemans D, Denef C (1995) Interaction of LHRH with growth hormone-releasing factor-dependent and -independent postnatal development of somatotrophs in rat pituitary cell aggregates. J Mol Endocrinol 14:91-100
41. Ying S-Y (1988) Inhibins, activins, and follistatins: gonadal proteins modulating the secretion of follicle-stimulating hormone. Endocrine Rev 9:267-293