Isoflurane inhibits endothelium-mediated nitric oxide relaxing pathways in the isolated perfused rabbit lung

Canadian Journal of Anaesthesia

Volumn 44, Issue 10, 1997, Pages 1108-1114

  Oshima, Yoshiaki ^a   Ishibe, Yuichi ^a   Okazaki, Naoto ^a   Sato, Toru ^a  

^a TOTTORI UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; GLYCERYL TRINITRATE; ISOFLURANE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; PROSTAGLANDIN F2 ALPHA;

ANIMAL TISSUE; ARTERY DILATATION; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; FEMALE; ISOLATED LUNG; LUNG CIRCULATION; LUNG VASCULAR RESISTANCE; NONHUMAN; PRIORITY JOURNAL; PULMONARY ARTERY; RABBIT;

EID: 0030667778     PISSN: 0832610X     EISSN: None     Source Type: Journal    
DOI: 10.1007/bf03019235     Document Type: Article

References (32)

1. Moncada S, Palmer RMJ, Higgs EA. Nitric oxide: physiology, pathophysiology and pharmacology. Pharmacol Rev 1991; 43: 109-42.
2. Muldoon SM, Hart JL, Bowen KA, Freas W. Attenuation of endothelium-mediated vasodilation by halothane. Anesthesiology 1988; 68: 31-7.
3. Su JY, Zhang CC. Intracellular mechanisms of halothane's effect on isolated aortic strips of the rabbit. Anesthesiology 1989; 71: 409-17.
4. Yoshida K, Okabe E. Selective impairment of endothelium-dependent relaxation by sevoflurane: oxygen free radicals participation. Anesthesiology 1992; 76: 440-7.
5. Uggeri MJ, Proctor GJ, Johns RA. Halothane, enflurane, and isoflurane attenuate both receptor and non-receptor mediated EDRF production in rat thoracic aorta. Anesthesiology 1992; 76: 1012-7.
6. Toda H, Nakamura K, Hatano Y, Nishiwada M, Kakuyama M, Mori K. Halothane and isoflurane inhibit endothelium-dependent relaxation elicited by acetylcholine. Anesth Analg 1992; 75: 198-203.
7. Hart JL, Jing M, Bina S, Freas W, Van Dyke RA, Muldoon SM. Effects of halothane on EDRF/cGMP-mediated vascular smooth muscle relaxations. Anesthesiology 1993; 79: 323-31.
8. Nakamura K, Terasako K, Toda H, et al. Mechanisms of inhibition of endothelium-dependent relaxation by halothane, isoflurane, and sevoflurane. Can J Anaesth 1994; 41: 340-6.
9. Akata T, Nakashima M, Kodama K, Boyle WA III, Takahashi S. Effects of volatile anesthetics on acethylcholine-induced relaxation in the rabbit mesenteric resistance artery. Anesthesiology 1995; 82: 188-204.
10. Marshall C, Lindgren L, Marshall BE. Effects of halothane, enflurane, and isoflurane on hypoxic pulmonary vasoconstriction in rat lungs in vitro. Anesthesiology 1984; 60: 304-8.
11. Ishibe Y, Gui X, Uno H, Shiokawa T, Umeda T, Suekane K. Effect of sevoflurane on hypoxic pulmonary vasoconstriction in the perfused rabbit lung. Anesthesiology 1993; 79: 1348-53.
12. Chen G, Suzuki H, Weston AH. Acetylcholine releases endothelium-derived hyperpolarizing factor and EDRF from the rat blood vessels. Br J Pharmacol 1988; 95: 1165-74.
13. G-nitro-L-arginine in rats. Am J Physiol 1992; 263: H1090-4.
14. +]: a functional approach to separating EDHF- and EDNO-related mechanisms in perfused rat mesenteric arterial bed. J Cardiovasc Pharmacol 1993; 21: 423-9.
15. Marshall C, Ishibe Y, Marshall BE. A combined in vivo/in vitro small animal model for studying pulmonary responses. Methods Find Exp Clin Pharmacol 1988; 10: 5-11.
16. Catravas JD, Buccafusco JJ, Kashef HE. Effects of acetylcholine in the pulmonary circulation of rabbits. J Pharmacol Exp Ther 1984; 231: 236-41.
17. Drummond JC. MAC for halothane, enflurane, and isoflurane in the New Zealand white rabbit: and a test for the validity of MAC determinations. Anesthesiology 1985; 62: 336-8.
18. 2+ influx in bovine aortic endothelial cells. Anesthesiology 1996; 85: 366-79.
19. Lischke V, Busse R, Hecker M. Inhalation anesthetics inhibit the release of endothelium-derived hyperpolarizing factor in the rabbit carotid artery. Anesthesiology 1995; 83: 574-82.
20. Tsukiyama Y, Iranami H, Yamamoto M, Nishiura N, Hatano Y. Halothane and isoflurane do not inhibit the relaxant response response elicited by acetylcholine in perfused rat mesenteric arterial beds. Anesthesiology 1993; 79: A660.
21. Iranami H, Tsukiyama Y, Yamamoto M, Tsuchiyama Y, Hatano Y. Differences in the inhibition by halothane of acetylcholine-induced relaxation in rat aorta and mesenteric artery. Anesthesiology 1993; 79: A661.
22. Tsukiyama Y, Iranami H, Tsuchiyama Y, Nishiura N, Hatano Y. The endothelium derived hyperpolarization factor-mediated vasodilation is inhibited by halothane in rat mesenteric arterial beds. Anesthesiology 1994; 81: A678.
23. Murray PA, Fehr DM, Chen BB, et al. Differential effects of general anesthesia on cGMP-mediated pulmonary vasodilation. J Appl Physiol 1992; 73: 721-7.
24. Gambone LM, Fuziwara Y, Murray PA. Endothelium-dependent cGMP-mediated pulmonary vasodilation is selectively attenuated during isoflurane anesthesia compared to the conscious state. Anesthesiology 1993; 79: A681.
25. Sugimori K, Comporesi EM, Hakim TS. The effect of halothane on nitric oxide-induced relaxation in rat pulmonary artery and aorta. Anesthesiology 1995; 83: A1195.
26. Blaise G, To Q, Parent M, Lagarde B, Asenjo R, Sauvé R. Does halothane interfere with the release, action, or stability of endothelium-derived relaxing factor/nitric oxide. Anesthesiology 1994; 80: 417-26.
27. Blaise G, To Q. Isoflurane decreases EDRF/NO action but not its production. Anesthesiology 1993; 79: A670.
28. Chen G, Suzuki H. Some electrical properties of the endothelium-dependent hyperpolarization recorded from rat arterial smooth muscle cells. J Physiol (Lond) 1989; 410: 91-106.
29. 2. J Pharmacol Exp Ther 1986; 236: 535-41.
30. Barnes SD, Martin LD, Wetzel RC. Halothane enhances pulmonary artery endothelial eicosanoid release. Anesth Analg 1992; 75: 1007-13.
31. Loeb AL, O'Brien DK, Longnecker DE. Halothane inhibits bradykinin-stimulated prostacyclin production in endothelial cells. Anesthesiology 1994; 81: 931-8.
32. Gambone LM, Flavahan NA, Murray PA. Attenuation of bradykinin-induced vasorelaxation by isoflurane is unmasked by cyclooxygenase inhibition in isolated canine pulmonary arteries. Anesthesiology 1994; 81: A700.