Functional interaction of a novel cellular protein with the papillomavirus E2 transactivation domain

Molecular and Cellular Biology

Volumn 17, Issue 12, 1997, Pages 7208-7219

  Breiding, David E ^a   Sverdrup, Francis ^a   Grossel, Martha J ^a,b   Moscufo, Nicola ^a,c   Boonchai, Waranya ^a,d   Androphy, Elliot J ^a  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^d MAHIDOL UNIVERSITY   (Thailand)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; INITIATION FACTOR; PROTEIN AMF 1; UNCLASSIFIED DRUG;

ARTICLE; DEFECTIVE VIRUS; HELA CELL; HUMAN; HUMAN CELL; NONHUMAN; PAPILLOMA VIRUS; POINT MUTATION; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; TRANSACTIVATION; VIRUS MUTANT;

BOVINAE; BOVINE PAPILLOMAVIRUS; BOVINE PAPILLOMAVIRUS TYPE 1; MAMMALIA; PAPILLOMAVIRUS;

EID: 0030667739     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.17.12.7208     Document Type: Article

References (48)

1. Abroi, A., R. Kurg, and M. Ustav. 1996. Transcriptional and replicational activation functions in the bovine papillomavirus type 1 E2 protein are encoded by different structural determinants. J. Virol. 70:6169-6179.
2. Altschul, S. F., W. Gish, W. Miller, E. W. Meyers, and D. J. Lipman. 1990. Basis local alignment search tool. J. Mol. Biol. 215:403-410.
3. Ausubel, M. A., R. Brent, R. E. Kingston, D. D. Moore, J. G. Seidman, J. A. Smith, and K. Struhl. (ed.). 1993. Current protocols in molecular biology. Green Publishing Associates, Boston, Mass.
4. Benson, J. D., and P. Howley. 1995. Amino-terminal domains of the bovine papillomavirus type 1 E1 and E2 proteins participate in complex formation. J. Virol. 69:4364-4372.
5. Bonne-Andrea, C., S. Santucci, P. Clertant, and F. Tillier. 1995. Bovine papillomavirus E1 protein binds specifically DNA polymerase alpha but not replication protein A. J. Virol. 69:2341-2350.
6. Breiding, D. E., E. J. Androphy, R. Kovelman, and M. Barbosa. Unpublished data.
7. Breiding, D. E., M. J. Grossel, and E. J. Androphy. 1996. Genetic analysis of the bovine papillomavirus E2 transcriptional activation domain. Virology 221:34-43.
8. Brokaw, J. L., M. Blanco, and A. A. McBride. 1996. Amino acids critical for the functions of the bovine papillomavirus type 1 E2 transactivator. J. Virol. 70:23-29.
9. Chen, C., and H. Okayama. 1992. High-efficiency transformation of mammalian cells by plasmid DNA. Mol. Cell. Biol. 7:2745-2752.
10. Chen, J., C. Reid, V. Band, and E. Androphy. 1995. Interaction of papillomavirus E6 oncoproteins with a putative calcium binding protein. Science 269:529-531.
11. Dalton, S., and R. Treisman. 1992. Characterization of SAP-1, a protein recruited by serum response factor to the c-fos serum response element. Cell 68:597-612.
12. Ferguson, M. K., and M. R. Botchan. 1996. Genetic analysis of the activation domain of bovine papillomavirus protein E2: its role in transcription and replication. J. Virol. 70:4193-4199.
13. Gietz, R. D. 1988. New yeast-E. coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six base pair restriction sites. Gene 74:527-534.
14. Giri, I., and M. Yaniv. 1988. Structural and mutational analysis of E2 transactivating proteins of papillomaviruses reveals three distinct functional domains. EMBO J. 7:2823-2829.
15. Goodrich, J. A., G. Cutler, and R. Tjian. 1996. Contacts in context: promoter specificity and macromolecular interactions in transcription. Cell 84:825-830.
16. Grossel, M. J., F. Sverdrup, D. E. Breiding, and E. J. Androphy. 1996. Transcriptional activation function is not required for stimulation of DNA replication by bovine papillomavirus type 1 E2. J. Virol. 70:7264-7269.
17. Guarente, L., and T. Mason. 1983. Heme regulates transcription of the CYC1 gene of S. cerevisiae via an upstream activation site. Cell 32:1279-1286.
18. Gyuris, J., E. Golemis, H. Chertkov, and R. Brent. 1993. Cdi1, a human G1 and S phase protein phosphatase that associates with Cdk2. Cell 75:791-803.
19. Ham, J., N. Dostatni, F. Arnos, and M. Yaniv. 1991. Several different upstream promoter elements can potentiate transactivation by the BPV-1 E2 protein. EMBO J. 10:2931-2940.
20. Haugen, T. H., L. P. Turek, F. M. Mercurio, T. P. Cripe, B. J. Olson, R. D. Anderson, D. Seidl, M. Karin, and J. Schiller. 1988. Sequence-specific and general transcriptional activation by the bovine papillomavirus-1 E2 transactivator require an N-terminal amphipathic helix-containing E2 domain. EMBO J. 7:4245-4253.
21. Kelly, W. G., M. E. Dahmus, and G. W. Hart. 1993. RNA polymerase II is a glycoprotein modification of the COOH-terminal domain by O-GlcNAc. J. Biol. Chem. 268:10416-10424.
22. Kingston, R. E., C. A. Bunker, and A. N. Imbalzano. 1996. Repression and activation by multiprotein complexes that alter chromatin structure. Genes Dev. 10:905-920.
23. Lambert, P. F., N. Dostatni, A. A. McBride, M. Yaniv, and P. M. Howley. 1989. Functional analysis of the papilloma virus E2 trans-activator in Saccharomyces cerevisiae. Genes Dev. 3:38-48.
24. Lange-Carter, C., C. Pleiman, A. M. Gardner, K. J. Blumer, and G. L. Johnson. 1993. A divergence in the MAP kinase regulatory network defined by MEK kinase and raf. Science 260:315-319.
25. Lee, J. W., F. Ryan, J. C. Swaffield, S. A. Johnston, and D. D. Moore. 1995. Interaction of thyroid-hormone receptor with a conserved transcriptional mediator. Nature 374:91-94.
26. Li, R., and M. Botchan. 1994. Acidic transcription factors alleviate nucleosome-mediated repression of DNA replication of bovine papillomavirus type 1. Proc. Natl. Acad. Sci. USA 91:7051-7055.
27. Li, R., J. D. Knight, S. P. Jackson, R. Tjian, and M. R. Botchan. 1991. Direct interaction between Sp1 and the BPV enhancer E2 protein mediates synergistic activation of transcription. Cell 65:493-505.
28. McBride, A. A., J. C. Byrne, and P. M. Howley. 1989. E2 polypeptides encoded by bovine papillomavirus type 1 form dimers through the common carboxyl-terminal domain: transactivation is mediated by the conserved amino-terminal domain. Proc. Natl. Acad. Sci. USA 86:510-514.
29. Mohr, I. J., R. Clark, S. Sun, E. J. Androphy, P. MacPherson, and M. R. Botchan. 1990. Targeting the E1 replication protein to the papillomavirus origin of replication by complex formation with the E2 transactivator. Science 250:1694-1699.
30. Morrissey, L. C., J. Barsoum, and E. J. Androphy. 1989. trans activation by the bovine papillomavirus E2 protein in Saccharomyces cerevisiae. J. Virol. 63:4422-4425.
31. Nilson, M., M. Forsberg, Z. You, G. Westin, and G. Magnusson. 1991. Enhancer effect of bovine papillomavirus E2 protein in replication of polyomavirus DNA. Nucleic Acids Res. 19:7061-7065.
32. Onate, S. A., Y. T. Tsai, M. J. Tsai, and B. W. O'Malley. 1995. Sequence and characterization of a coactivator for the steroid hormone receptor family. Science 270:1354-1356.
33. Prakash, S. S., S. R. Grossman, R. B. Pepinsky, L. A. Laimins, and E. J. Androphy. 1992. Amino acids necessary for DNA contact and dimerization imply novel motifs in the papillomavirus E2 trans-activator. Genes Dev. 6:105-116.
34. Rank, N. M., and P. F. Lambert. 1995. Bovine papillomavirus type 1 E2 transcriptional regulators directly bind two cellular transcription factors, TFIID and TFIIB. J. Virol. 69:6323-6334.
35. Sakai, H., T. Yasugi, J. D. Benson, J. J. Dowhanick, and P. M. Howley. 1996. Targeted mutagenesis of the human papillomavirus type 16 E2 transactivation domain reveals separable transcriptional activation and DNA replication functions. J. Virol. 70:1602-1611.
36. Seo, Y.-S., F. Muller, M. Lusky, E. Gibbs, H.-Y. Kim, B. Phillips, and J. Hurwitz. 1993. Bovine papilloma virus (BPV)-encoded E2 protein enhances binding of E1 protein to the BPV replication origin. Proc. Natl. Acad. Sci. USA 90:2865-2869.
37. Spain, B. H., K. S. Bowdish, A. R. Pacal, S. F. Staub, D. Koo, C. Y. Chang, W. Xie, and J. Colicelli. 1996. Two human cDNAs, including a homolog of Arabidopsis FYS6 (COP 11), suppress G-protein-and mitogen-activated protein kinase-mediated signal transduction in yeast and mammalian cells. Mol. Cell. Biol. 16:6698-6706.
38. Spain, B. H., D. Koo, M. Ramakrishnan, B. Dzudzor, and J. Colicelli. 1995. Truncated forms of a novel yeast protein suppress the lethality of αG protein a subunit deficiency by interacting with the β subunit. J. Biol. Chem. 270: 25435-25444.
39. Steger, G., J. Ham, O. Lefebvre, and M. Yaniv. 1995. The bovine papillomavirus 1 E2 protein contains two activation domains: one that interacts with TBP and another that functions after TBP binding. EMBO J. 14:329-340.
40. Studier, F. W., A. H. Rosenberg, J. J. Dunn, and J. W. Dubendorff. 1990. Use of T7 RNA polymerase to direct expression of cloned genes. Methods Enzymol. 185:60-89.
41. Thorner, L., D. Lim, and M. Botchan. 1993. DNA-binding domain of bovine papillomavirus type 1 E1 helicase: structural and functional aspects. J. Virol. 67:6000-6014.
42. Ushikai, M., M. J. Lace, Y. Yamakawa, M. Kono, J. Anson, T. Ishiji, S. Parkkinen, N. Wicker, M.-E. Valentine, I. Davidson, L. P. Turek, and T. H. Haugen. 1994. trans activation by the full-length E2 proteins of human papillomavirus type 16 and bovine papillomavirus type 1 in vitro and in vivo: cooperation with activation domains of cellular transcription factors. J. Virol. 68:6655-6666.
43. Ustav, E., M. Ustav, P. Szymanski, and A. Stenlund. 1993. The bovine papillomavirus origin of replication requires a binding site for the E2 transcriptional activator. Proc. Natl. Acad. Sci. U. S. A. 90:898-902.
44. Ustav, M., and A. Stenlund. 1991. Transient replication of BPV-1 requires two viral polypeptides encoded by the E1 and E2 open reading frames. EMBO J. 10:449-457.
45. vom Baur, E., C. Zechel, D. Heery, M. J. S. Heine, J. M. Garnier, V. Vivat, B. Le Dourin, H. Gronemeyer, P. Chambon, and R. Losson. 1996. Differential ligand-dependent interactions between the AF-2 activating domain of nuclear receptors and the putative transcriptional intermediary factors mSUG1 and TIF1. EMBO J. 15:110-124.
46. Winokur, P. L., and A. A. McBride. 1996. The transactivation and DNA binding domains of the BPV-1 E2 protein have different roles in cooperative origin binding with the E1 protein. Virology 221:44-53.
47. Yang, L., R. Li, I. J. Mohr, and M. R. Botchan. 1991. Activation of BPV-1 replication in vitro by the transcription factor E2. Nature 353:628-632.
48. Yang, L. I., I. Mohr, D. A. Fouts, L. Nohile, and M. R. Botchan. 1993. The E1 protein of the papillomavirus is an ATP dependent DNA helicase. Proc. Natl. Acad. Sci. USA 90:5086-5090.