Effects of aldehyde/aldose reductase inhibition on neuronal metabolism of norepinephrine

Journal of the Autonomic Nervous System

Volumn 66, Issue 3, 1997, Pages 145-148

  Kawamura, Minoru ^a,c   Kopin, Irwin J ^a   Kador, Peter F ^b   Sato, Sanai ^b   Tjurmina, Olga ^a   Eisenhofer, Graeme ^a  

^a NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^b NATIONAL EYE INSTITUTE   (United States)

^c Nippon Zoki Pharmaceutical Co Ltd   (Japan)

Author keywords

3,4 Dihydroxymandelic acid; 3,4 Dihydroxyphenylglycol; Aldehyde reductase; Monoamine oxidase; Norepinephrine; Sympathetic nervous system

Indexed keywords

3,4 DIHYDROXYMANDELIC ACID; 3,4 DIHYDROXYPHENYLETHYLENE GLYCOL; ALDEHYDE REDUCTASE; IMIRESTAT; NORADRENALIN;

ADRENERGIC SYSTEM; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD LEVEL; BRAIN TISSUE; CONTROLLED STUDY; ELECTROCHEMICAL DETECTION; ENZYME ACTIVITY; LIQUID CHROMATOGRAPHY; MALE; METABOLISM; NONHUMAN; PRIORITY JOURNAL; RAT;

ALDEHYDE REDUCTASE; ANIMALS; BRAIN CHEMISTRY; CATECHOLAMINES; ENZYME INHIBITORS; MALE; MANDELIC ACIDS; METHOXYHYDROXYPHENYLGLYCOL; NEURONS; NOREPINEPHRINE; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0030667647     PISSN: 01651838     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-1838(97)00086-6     Document Type: Article

References (16)

1. W.J. Burke, M.B. Mattammal, G.L. Marshall, H. Chung, Detection of 3,4-dihydroxyphenylglycolaldehyde in human brain by high-performance liquid chromatography, Anal. Biochem. 180 (1989) 79-84.
2. W.X. Dong, J. Schneider, P. Lacolley, A.-M. Brisac, M. Safar, J.L. Cuche, Neuronal metabolism of catecholamines: Plasma DHPG, DOMA and DOPAC, J. Auton. Nerv. Syst. 44 (1993) 109-117.
3. W.X. Dong, J. Schneider, H. Dabire, M. Safar, J.-L Cuche, Neuronal metabolism of catecholamines in pithed and electrically stimulated rats, J. Auton. Nerv. Syst. 54 (1995) 41-48.
4. G. Eisenhofer, D.S. Goldstein, T.G. Ropchak, H.Q. Nguyen, H.R. Keiser, I.J. Kopin, Source and physiological significance of plasma 3,4-dihydroxyphenylglycol and 3-methoxy-4-hydroxyphenylglycol, J. Auton. Nerv. Syst. 24 (1988) 1-14.
5. G. Eisenhofer, D.S. Goldstein, R. Stull, H.R. Keiser, T. Sunderland, D.L. Murphy, I.J. Kopin, Simultaneous liquid-chromatographic determination of 3,4-dihydroxyphenylglycol, catecholamines, and 3,4-dihydroxyphenylalanine in plasma and their responses to inhibition of monoamine oxidase, Clin. Chem. 32 (1986) 2030-2033.
6. G. Eisenhofer, W. Pecorella, K. Pacak, D. Hooper, I.J. Kopin, D.S. Goldstein, The neuronal and extraneuronal origins of plasma 3-methoxy-4-hydroxyphenylglycol in rats, J. Auton. Nerv. Syst. 50 (1994) 93-107.
7. B.M. Eriksson, B.A. Personn, Liquid chromatographic method for the determination of 3,4-dihydroxyphenylethyleneglycol and 3,4-dihydroxymandelic acid in plasma, J. Chromatogr. 386 (1987) 1-9.
8. 3H-(-)noradrenaline in the perfused cat and rabbit heart, Naunyn-Schmiedebergs Arch. Pharmacol. 318 (1981) 71-82.
9. 3H]noradrenaline kinetics using high-performance liquid chromatography, Clin. Sci. 71 (1986) 211-215.
10. I.J. Kopin, Catecholamine metabolism: Basic aspects and clinical significance, Pharmacol. Rev. 37 (1985) 333-364.
11. J.L. Izzo, D.A. Thompson, D. Horwitz, Plasma dihydroxyphenylglycol (DHPG) in the in vivo assessment of human neuronal norepinephrine metabolism, Life Sci. 37 (1985) 1033-1038.
12. M. Mizukoshi, T. Hano, M. Kuchii, I. Nishio, Y. Masuyama, Plasma noradrenaline and its deaminated metabolites in essential hypertension and pheochromocytoma, Jpn. Circ. J. 49 (1985) 1035-1042.
13. S. Sato, P.F. Kador, Inhibition of aldehyde reductase by aldose reductase inhibitors, Biochem. Pharmacol. 40 (1990) 1033-1042.
14. U. Trendelenburg, H. Bönisch, K.-H. Graefe, M. Henseling, The rate constants for the efflux of metabolites of catecholamines and phenethylamines, Pharmacol. Rev. 31 (1979) 179-203.
15. N.D. Vlachakis, C. Lampano, N. Alexander, R.F. Maronde, Catecholamines and their major metabolites in plasma and cerebrospinal fluid of man, Brain Res. 229 (1981) 67-74.
16. B. Wermuth, Aldo-keto reductases, in: H. Weiner, B. Wermuth (Eds.), Enzymology of Carbonyl Metabolism 2: Aldehyde Dehydrogenase, Aldo Keto Reductase and Alcohol Dehydrogenase, Alan R. Liss, New York, 1985, pp. 209-230.