Effects of varying lengths of double-stranded RNA on binding and activation of 2'-5'-oligoadenylate synthetase

Journal of Interferon and Cytokine Research

Volumn 17, Issue 9, 1997, Pages 531-536

  Desai, Shailesh Y ^a   Sen, Ganes C ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2',5' OLIGOADENYLATE SYNTHETASE; DOUBLE STRANDED RNA; INTERFERON; RECOMBINANT ENZYME; RNA BINDING PROTEIN;

ARTICLE; BACTERIUM; DIMERIZATION; ELECTROPHORETIC MOBILITY; ENZYME ACTIVATION; ENZYME KINETICS; ENZYME PURIFICATION; ISOTOPE LABELING; NONHUMAN; PRIORITY JOURNAL; RNA BINDING; TRANSCRIPTION REGULATION;

BACTERIA (MICROORGANISMS);

EID: 0030667471     PISSN: 10799907     EISSN: None     Source Type: Journal    
DOI: 10.1089/jir.1997.17.531     Document Type: Article

References (20)

1. VILCEK, J., and SEN, G.C. (1996). Interferons and other cytokines. In: Fields Virology, 3rd ed. B.N. Field, D.M. Knipe, P.M. Howley, et al. (eds.) Philadelphia: Lippincott-Raven, pp. 375-399.
2. HOVANESSIAN, A. (1991). RNA-activated enzymes: a specific protein kinase and 2′-5′ oligoadenylate synthetases. J. Interferon Res. 11, 199-205.
3. SILVERMAN, R.H. (1996). 2-5 A-dependent RNase L: a regulated endoribonuclease in the interferon system. In: Ribonucleases: Structure and Function. G. D'Alessio and J.F. Riordan. New York: Academic Press, pp. 515-551.
4. GHOSH, S.K., KUSARI, J., BANDYOPADHYAY, S.K., SAMANTA, H., KUMAR, R., and SEN, G.C. (1991). Cloning, sequencing, and expression of two murine 2′-5′ oligoadenylate synthetases: structure-function relationships. J. Biol. Chem. 266, 15293-15299.
5. MARAN, A., MAITRA, R.K., KUMAR, A., DONG, B., XIAO, W., LI, G., WILLIAMS, B.R.G., TORRENCE, P.F., and SILVERMAN, R.H. (1994). Blockage of NF-κB signaling by selective ablation of an mRNA target by 2-5A antisense chimeras. Science 265, 789-792.
6. SAMUEL, C.E. (1993). The eIF-2α protein kinases, regulators of translation in eukaryotes from yeasts to humans. J. Biol. Chem. 268, 7603-7606.
7. PATEL, R.C., and SEN, G.C. (1992). Identification of the double-stranded RNA-binding domain of the human interferon-inducible protein kinase. J. Biol. Chem. 267, 7671-7676.
8. McCORMACK, S.J., THOMIS, D.C., and SAMUEL, C.E. (1992). Mechanism of interferon action: identification of a RNA binding domain within the N-terminal region of the human RNA-dependent P1/eIF-2α protein kinase. Virology 188, 47-56.
9. FENG, G.S., CHONG, K., KUMAR, A., and WILLIAMS, B.R.G. (1992). Identification of double-stranded RNA-binding domains in the interferon-induced double-stranded RNA-activated p68 kinase. Proc. Natl. Acad. Sci. USA 89, 5447-5451.
10. KATZE, M.G., WAMBACK, M., WONG, M.L., GARFINKEL, M., MEURS, E., CHONG, K., WILLIAMS, B.R., HOVANESSIAN, A.G., and BARBER, G.N. (1991). Functional expression and RNA binding analysis of the interferon-induced double-stranded RNA-activated 68,000 Mγ protein kinase in a cell-free system. Mol. Cell. Biol. 11, 5497-5505.
11. GREEN, S.R., and MATHEWS, M.B. (1992). Two RNA binding motifs in the double-stranded RNA activated protein kinase DAI. Genes Dev. 6, 2478-2490.
12. PATEL, R.C., STANTON, P., McMILLAN, N.M.J., WILLIAMS, B.R.G., and SEN, G.C. (1995). The interferon-inducible double-stranded RNA-activated protein kinase self-associates in vitro and in vivo. Proc. Natl. Acad. Sci. USA 92, 8283-8287.
13. PATEL, R., STANTON, P., and SEN, G.C. (1996). Specific mutations near the amino terminus of double-stranded RNA-dependent protein kinase (PKR) differentially affect its double-stranded RNA binding and dimerization properties. J. Biol. Chem. 271, 25657-25663.
14. ST. JOHNSTON, D., BROWN, N.H., GALL, J.G., and JANTSCH, M. (1992). A conserved double-stranded RNA-binding domain. Proc. Natl. Acad. Sci. USA 89, 10979-10983.
15. DESAI, S.V., PATEL, R.C., SEN, G.C., MALHOTRA, P., GHADGE, G.D., and THIMMAPAYA, B. (1995). Activation of interferon-inducible 2′-5′ oligoadenylate synthetase by adenoviral VAI RNA. J. Biol. Chem. 270, 3454-3461.
16. MAITRA, R.K., McMILLAN, N., DESAI, S., McSWIGGEN, J., HOVANESSIAN, A.G., SEN, G.C., WILLIAMS, B.R.G., and SILVERMAN, R.H. (1994). HIV-1 TAR RNA has an intrinsic ability to activate interferon-inducible enzymes. Virology 204, 823-827.
17. MANCHE, L., GREEN, S.R., SCHMEDT, C., and MATHEWS, M.B. (1992). Interactions between double-stranded RNA regulators and the protein kinase DAI. Mol. Cell. Biol. 12, 5238-5248.
18. MORY, Y., VAKS, B., and CHEBATH, J. (1989). Production of two human 2′-5′-oligoadenylate synthetase enzymes in Escherichia coli. J. Interferon Res. 9, 295-304.
19. MINKS, M.A., WEST, D.K., BENVIN, S., and BAGLIONI, C. (1979). Structural requirement of double-stranded RNA for the activation of 2′5′-oligo (A) polymerase and protein kinase of interferon-treated HeLa cells. J. Biol. Chem. 254, 10180-10183.
20. MINKS, M.A., WEST, D.K., BENVIN, S., GREEN, J.J., TS'O, P.O.P., and BAGLIONI, C. (1980). Activation of 2′,5′-oligo (A) polymerase and protein kinase of interferon-treated HeLa cells by 2′-O-methylated poly (inosinic acid) poly (cytidylic acid). J. Biol. Chem. 255, 6403-6407.