Cross-resistance to both atracurium- and vecuronium-induced neuromuscular blockade in a critically Ill patient

Pharmacotherapy

Volumn 17, Issue 6, 1997, Pages 1322-1327

  Fish, Douglas N ^a   Singletary, Tony J ^a  

^a UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATRACURIUM; CEFTRIAXONE; FENTANYL; IPRATROPIUM BROMIDE; MIDAZOLAM; SALBUTAMOL; SUCRALFATE; VECURONIUM;

ADULT; ADULT RESPIRATORY DISTRESS SYNDROME; ARTICLE; ARTIFICIAL VENTILATION; CASE REPORT; CROSS RESISTANCE; FEMALE; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; LOBAR PNEUMONIA; NEUROMUSCULAR BLOCKING; SEPTIC SHOCK;

ADULT; ATRACURIUM; CRITICAL ILLNESS; CROSS REACTIONS; DRUG RESISTANCE; FEMALE; HUMANS; NEUROMUSCULAR NONDEPOLARIZING AGENTS; RESPIRATION, ARTIFICIAL; RESPIRATORY DISTRESS SYNDROME, ADULT; RESPIRATORY FUNCTION TESTS; VECURONIUM BROMIDE;

EID: 0030667462     PISSN: 02770008     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (38)

1. Prielipp RC, Coursin DB. Applied pharmacology of common neuromuscular blocking agents in critical care. New Horizons 1994;2:34-47.
2. Hansen-Flaschen JH, Brazinsky S, Basile C, et al. Use of sedating drugs and neuromuscular blocking agents in patients requiring mechanical ventilation for respiratory failure. JAMA 1991;266:2870-6.
3. Klessig HT, Geiger HJ, Murray MJ, et al. A national survey on the practice patterns of anesthesiologist intensivists in the use of muscle relaxants. Crit Care Med 1992;20:1341-5.
4. Davidson JE. Neuromuscular blockade: indications, peripheral nerve stimulation, and other concurrent interventions. Crit Care Med 1994;2:75-84.
5. Coursin DB, Klasek G, Goelzer SL. Increased requirements for continuously infused vecuronium in critically ill patients. Anesth Analg 1989;69:518-21.
6. Parr SM, Galletly DC, Robinson BJ. Betamethasone-induced resistance to vecuronium: a potential problem in neurosurgery? Anaesth Intensive Care 1991;19:103-5.
7. Callanan DL. Development of resistance to pancuronium in adult respiratory distress syndrome. Anesth Analg 1985;64: 1126-8.
8. Yamashita M, Shiga T, Matsuki A, Oyama T. Unusual resistance to pancuronium in severely burned patients: case reports. Can Anaesth Soc J 1982;29:630-1.
9. Azar I, Kumar D, Betcher AM. Resistance to pancuronium in an asthmatic patient treated with aminophylline and steroids. Can Anaesth Soc J 1982;29:280-2.
10. Dwersteg JF, Pavlin EG, Heimbach DM. Patients with burns are resistant to atracurium. Anesthesiology 1986;65:517-20.
11. Yate PM, Flynn PJ, Arnold RW, et al. Clinical experience and plasma laudanosine concentrations during the infusion of atracurium in the intensive care unit. Br J Anaesth 1987;59: 211-17.
12. Kushimo OT, Darowski MJ, Morris P, et al. Dose requirements of atracurium in paediatric intensive care patients. Br J Anaesth 1991;67:781-3.
13. Kelly KJ, Clarens DM, Kohls PR, et al. Response to pancuronium after loss of atracurium-induced neuromuscular blockade. Ann Pharmacother 1993;27:862-5.
14. Tschida SJ, Hoey LL, Nahum A, Vance-Bryan K. Atracurium resistance in a critically ill patient. Pharmacotherapy 1995;15: 533-9.
15. Coursin DB, Meyer DA, Prielipp RC. Doxacurium infusions in critically ill patients with atracurium tachyphylaxis. Am J Health-Syst Pharm 1995;52:635-9.
16. Martyn JAJ, White DA, Gronert GA, et al. Up- and-down regulation of skeletal muscle acetylcholine receptors. Effects on neuromuscular blockers. Anesthesiology 1992;76:822-43.
17. Tschida SJ, Graupe KJ, Hoey LL, Vance-Bryan K. Resistance to nondepolarizing neuromuscular blocking agents. Pharmacotherapy 1996;16:409-18.
18. Kelly JS, MacGregor DA. Drugs acting at the cholinergic receptor. In: Chernow B, ed. The pharmacologie approach to the critically ill patient, 3rd ed. Baltimore: Williams & Wilkins, 1994:534-47.
19. McEvoy GK, Litvak K, Welsh OH Jr, eds. Atracurium and vecuronium drug monographs. In: AHFS 96 drug information. Bethesda, MD: American Society of Health-System Pharmacists, 1996:931-6, 945-51.
20. Hunter JM. Resistance to non-depolarizing neuromuscular blocking agents. Br J Anaesth 1991;67:511-14.
21. Neill AEM, Chapple DJ. Metabolism and kinetics of atracurium: an overview. Br J Anaesth 1983;55:23S-5.
22. Platt M, Hayward A, Cooper A, Hirsch N. Effect of arterial carbon dioxide tension on the duration of action of atracurium. Br J Anaesth 1991;66:45-7.
23. Ornstein E, Matteo RS, Schwartz AE, Silverberg PA, Young WL, Diaz J. The effect of phenytoin on the magnitude and duration of neuromuscular block following atracurium or vecuronium. Anesthesiology 1987;67:191-6.
24. Platt PR, Thackray NM. Phenytoin-induced resistance to vecuronium. Anaesth Intensive Care 1993;21:185-91.
25. Daller JA, Erstad B, Rosado L, Otto C, Putnam CW. Aminophylline antagonizes the neuromuscular blockade of pancuronium but not vecuronium. Crit Care Med 1991;19: 983-5.
26. Law SC. Intravenous ranitidine antagonizes intense atracurium-induced neuromuscular blockade in rats. Anesth Analg 1989;69:611-13.
27. Yanez P, Martyn JAJ. Prolonged d-tubocurarine infusion and/or immobilization cause upregulation of acetylcholine receptors and hyperkalemia to succinylcholine in rats. Anesthesiology 1996;84:384-91.
28. Kim C, Hirose M, Martyn JAJ. d-Tubocurarine accentuates the burn-induced upregulation of nicotinic acetylcholine receptors at the muscle membrane. Anesthesiology 1995;83: 309-15.
29. Dodson BA, Kelly BJ, Braswell LM, Cohen NH. Changes in acetylcholine receptor number in muscle from critically ill patients receiving muscle relaxants: an investigation of the molecular mechanism of prolonged paralysis. Crit Care Med 1995;23:815-21.
30. Pestronk A, Drachman DB, Griffin JW. Effect of muscle disuse on acetylcholine receptors. Nature 1976;260:352-3.
31. Hogue CW Jr, Itani MS, Martyn JAJ. Resistance to d-tubocurarine in lower motor neuron injury is related to increased acetylcholine receptors at the neuromuscular junction. Anesthesiology 1990;73:703-9.
32. Kim C, Martyn JA, Fuke N. Burn injury to trunk of rat causes denervation-like responses in gastrocnemius muscle. J Appl Physiol 1988;65:1745-51.
33. Gronert GA, Matteo RS, Perkins S. Canine gastrocnemius disuse atrophy: resistance to paralysis by dimethyl tubocurarine. J Appl Physiol 1984;57:1502-6.
34. Shayevitz JR, Matteo RS. Decreased sensitivity to metocurine in patients with upper motoneuron disease. Anesth Analg 1985;64:767-72.
35. Paton WD, Waud DR. The margin of safety of neuromuscular transmission. J Physiol (Lond) 1967;191:59-90.
36. Hoyt JW. Persistent paralysis in critically ill patients after the use of neuromuscular blocking agents. New Horizons 1994;2:48-55.
37. Hansen-Flaschen J, Cowan J, Raps EC. Neuromuscular blockade in the ICU: More than we bargained for? Am Rev Respir Dis 1993;147:234-7.
38. Cardinale V, ed. 1996 drug topics red book. Montvale, NJ: Medical Economics, 1996:422, 546.