The effect of empiric and prophylactic treatment with fluconazole on yeast isolates in a surgical trauma intensive care unit

Archives of Surgery

Volumn 132, Issue 11, 1997, Pages 1184-1189

  Safran, David B ^a,b   Dawson, Eric ^a  

^a UNIVERSITY OF SOUTH ALABAMA MEDICAL CENTER   (United States)

^b UNIVERSITY OF SOUTH ALABAMA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FLUCONAZOLE;

CANDIDA GLABRATA; CANDIDA PARAPSILOSIS; CONFERENCE PAPER; CRITICAL ILLNESS; DRUG RESISTANCE; HUMAN; INTENSIVE CARE UNIT; MAJOR CLINICAL STUDY; MORTALITY; MYCOSIS; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SURGICAL PATIENT; YEAST;

EID: 0030667331     PISSN: 00040010     EISSN: None     Source Type: Journal    
DOI: 10.1001/archsurg.1997.01430350034006     Document Type: Conference Paper

References (34)

1. Beck-Sague CM, Jarvis WR, National Nosocomial Infections Surveillance System. Secular trends in the epidemiology of nosocomial fungal infections in the United States, 1980-1990. J Infect Dis. 1993;167:1247-1251.
2. Tang E, Tang G, Berne TV. Prognostic indicators in fungemia of the surgical patient. Arch Surg. 1993;128:759-763.
3. Soutter DI, Todd TRJ. Systemic candidiasis in a surgical intensive care unit. Can J Surg. 1986;29:197-199.
4. Marsh PK, Tally FP, Kellum J, Callow A, Gorbach SL. Candida infections in surgical patients. Ann Surg. 1983;198:42-47.
5. Burchard KW, Minor LB, Slotman GJ, Gann DS. Fungal sepsis in surgical patients. Arch Surg. 1983;118:217-221.
6. Dean DA, Burchard KW. Fungal infections in surgical patients. Am J Surg. 1996; 171:374-382.
7. Solomkin JS, Flohr AM, Simmons RL. Indications for therapy for fungemia in postoperative patients. Arch Surg. 1982;117:1272-1275.
8. Wey SB, Mori M, Pfaller MA, Woolson RF, Wenzel RP. Hospital-acquired candidemia: the attributable mortality and excess length of stay. Arch Intern Med. 1988;148:2642-2645.
9. Eubanks PJ, de Virgilio C, Klein S, Bongard F. Candida sepsis in surgical patients. Am J Surg. 1993;166:617-620.
10. Clements JS, Peacock JE. Amphotericin B revisited: reassessment of toxicity. Am J Med. 1990;88:5-22N-7N.
11. Solomkin JS, Flohr A, Simmons R. Candida infections in surgical patients: dose requirements and toxicity of amphotericin B. Ann Surg. 1982;195:177-185.
12. Rex JH, Bennett JE, Sugar AM, et al. A randomized trial comparing fluconazole with amphotericin B for the treatment of candidemia in patients without neutropenia. N Engl J Med. 1994;331:1325-1330.
13. Goodman JL, Winston DJ, Greenfield RA, et al. A controlled trial of fluconazole to prevent fungal infections in patients undergoing bone marrow transplantation. N Engl J Med. 1992;326:845-851.
14. Kujath P, Lerch K. New antimicrobial agents under clinical investigation, secondary mycosis in surgery: treatment with fluconazole. Infection. 1989;17:111-117.
15. Slavin MA, Osborne B, Adams R, et al. Efficacy and safety of fluconazole prophylaxis for fungal infections after marrow transplantation: a prospective, randomized, double-blind study. J Infect Dis. 1995;171:1545-1552.
16. Winston DJ, Chandrasekar PH, Lazarus HM, et al. Fluconazole prophylaxis of fungal infections in patients with acute leukemia. Ann Intern Med. 1993;118:495-503.
17. Goa KL, Barradell LB. Fluconazole: an update of its pharmacodynamic and pharmacokinetic properties and therapeutic use in major superficial and systemic mycoses in immunocompromised patients. Drugs. 1995;50:658-690.
18. Pfaller MA. Nosocomial candidiasis: emerging species, reservoirs, and modes of transmission. Clin Infect Dis. 1996;22(suppl 2):S89-S94.
19. Nguyen MH, Peacock JE, Morris AJ, et al. The changing face of candidemia: emergence of non-Candida albicans species and antifungal resistance. Am J Med. 1996;100:617-623.
20. Borg-von Zepelin M, Eiffert H, Kann M, Ruchel R. Changes in the spectrum of fungal isolates: results from clinical specimens gathered in 1987/88 compared with those in 1991/92 in the University Hospital Gottingen, Germany. Mycoses 1993;36:247-253.
21. Rex JR, Rinaldi MG, Pfaller MA. Resistance of Candida species to fluconazole. Antimicrob Agents Chemother. 1995;39:1-8.
22. Medoff G. New challenges to the therapy of systemic fungal infections. Trans Am Clin Climatologic Assoc. 1995;107:146-158.
23. Martins MD, Rex J. Resistance to antifungal agents in the critical care setting: problems and perspectives. New Horiz. 1996;4:338-344.
24. Wingard JR, Merz WG, Rinaldi MG, Miller CB, Karp JE, Saral R, Association of Torulopsis glabrata infections with fluconazole prophylaxis in neutropenic bone marrow transplant patients. Antimicrob Agents Chemother. 1993; 37:1847-1849.
25. Wingard JR, Merz WG, Rinaldi MG, Johnson TR, Karp JE, Saral R. Increase in Candida krusei infection among patients with bone marrow transplantation and neutropenia treated prophylactically with fluconazole. N Engl J Med. 1991;325: 1274-1277.
26. Casasnovas R-O, Caillot D, Solary E, et al. Prophylactic fluconazole and Candida krusei infections. N Engl J Med. 1992;326:891-892.
27. Brammer KW, Farrow PR, Faulkner JK. Pharmacokinetics and tissue penetration of fluconazole in humans. Rev Infect Dis. 1990;12(suppl 3):S318-S326.
28. Arias A, Arevalo MP, Andreu A, Rodriguez C, Sierra A. Candida glabrata: in vitro susceptibility of 84 isolates to eight antifungal agents. Chemotherapy. 1996;42: 107-111.
29. Grant SM, Clissold SP. Fluconazole: a review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in superficial and systemic mycoses. Drugs. 1990;39:877-916.
30. Berkowitz ID, Robboy SJ, Karchmer AW, Kunz LJ. Torulopsis glabrata fungemia: a clinical pathological study. Medicine. 1979;58:430-440.
31. Weems JJ. Candida parapsilosis: epidemiology, pathogenicity, clinical manifestations, and antimicrobial susceptibility. Clin Infect Dis. 1992;14:756-766.
32. Stone HH, Kolb LD, Currie CA, Geheber CE, Cuzzell JZ, Candida sepsis: pathogenesis and principles of treatment. Ann Surg. 1974;179:697-711.
33. Bernhardt HE, Orlando JC, Benfield JR, Hirose FM, Foos RY. Disseminated candidiasis in surgical patients. Surg Gynecol Obstet. 1972;134:819-825.
34. Nassoura Z, Ivatury RR, Simon RJ, Jabbour N, Stahl WM. Candiduria as an early marker of disseminated infection in critically ill surgical patients: the role of fluconazole therapy. J Trauma. 1993;35:290-295.