Effects of glutathione S-transferase GSTM1 and GSTT1 genotypes on lung cancer risk in smokers

Pharmacogenetics

Volumn 7, Issue 6, 1997, Pages 515-518

  Jourenkova, Nadejda ^a   Reinikanen, Maria ^b   Bouchardy, Christine ^c   Husgafvel Pursiainen, Kirsti ^b   Dayer, Pierre ^d   Benhamou, Simone ^a   Hirvonen, Ari ^b  

^a INSTITUT GUSTAVE ROUSSY   (France)

^b FINNISH INSTITUTE OF OCCUPATIONAL HEALTH   (Finland)

^c GENEVA CANCER REGISTRY   (Switzerland)

^d GENEVA UNIVERSITY HOSPITALS   (Switzerland)

Author keywords

Epidemiology; GSTM1; GSTT1; Lung cancer; Smoking

Indexed keywords

GLUTATHIONE TRANSFERASE; ISOENZYME;

CANCER RISK; GENOTYPE; HUMAN; LUNG CANCER; PRIORITY JOURNAL; SHORT SURVEY; SMOKING;

EID: 0030666707     PISSN: 0960314X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00008571-199712000-00010     Document Type: Short Survey

References (14)

1. Alexandrie AK, Sundberg MI, Seidegard J, Tornling G, Rannung A. Genetic susceptibility to lung cancer with special emphasis on CYP1A1 and GSTM1: A study on host factors in relation to age at onset, gender and histological cancer types. Carcinogeneis 1994: 15, 1785-1790.
2. Bouchardy C, Benhamou S, Dayer P. The effect of tobacco on lung canser risk depends on CYP2D6 activity. Cancer Res 1996: 56, 251-253.
3. Bouchardy C, Wikman H, Benhamou S, Hirvonen A, Dayer P, Husgafvel-Pursiainen K. CY1MA1 genetic polymorphisms, tobacco smoking and lung cancer risk in a French Caucasian population. Biomarkers 1997: 2, 131-134.
4. Breslow NE, Day NE. The analysis of case-control studies. In: Statistical methods in cancer research. Vol. 1. No. 32, Lyon, France: International Agency for Research on Cancer, 1980: 192-242.
5. Brockmöller J, Kerb R, Drakoulis N, Nitz M, Roots I. Genotype and phenotype of glutathione S-transferase class μ isoenzymes μ and ψ in lung cancer patients and controls. Cancer Res 1993: 53, 1004-1011.
6. Chen H, Sandler DP, Taylor JA, Shore DL, Edison L, Bloomfield CL, Bell DA. Increased risk for myelodysplastic syndromes in individuals with glutathione transferase theta 1 (GSTT1) gene defect. Lancet 1996: 347, 295-297.
7. Deakin M, Elder J, Hendrickse C, Peckham D, Baldwin D, Pantin C, Wild N, Leopard P, Bell DA, Jones P et al. Glutathione S-transferase GSTT1 genotypes and susceptibility to cancer: Studies of interactions with GSTM1 in lung, oral, gastric and colorectal cancer. Carcinogenesis 1996: 17, 881-884.
8. d'Errico A, Taioli E, Chen X, Vineis P. Genetic metabolic polymorphisms and the risk of cancer: A review of the literature. Biomarkers 1996: 1, 149-173.
9. Hirvonen A, Husgafvel-Pursiainen K, Antilla S, Vainio H. The CSTM1 null genotype as a potential modifier for squamous cell carcinoma of the lung. Carcinogenesis 1995: 14, 1479-1481.
10. Hirvonen A, Saarikoski ST, Koskinen KLK, Husgafvel-Pursiainen K, Mattson K, Vainio H. Glutathione S-transferase and N-acetyltransferase genotypes and asbestos-associated pulmonary disorders. J Natl Cancer Inst 1996: 88, 1853-1856.
11. International Agency for Research on Cancer. Tobacco smoking, monographs on the evaluation of the carcinogenic risk of chemicals to humans. Vol. 38. Lyon, France: International Agency for Research on Cancer. 1986: 58, 270-303.
12. London SJ, Daly AK, Cooper J, Navidi WC, Carpenter CL, Idle JR. Polymorphism of glutathione S-transferase M1 and lung cancer among African-Americans and Caucasians in Los Angeles County, California. J Natl Cancer Inst 1995: 87, 1246-1253.
13. Penible S, Schroeder KR, Spencer SK, Meyer DJ, Hallier E, Bolt HM, Ketterer H, Taylor JB. Human glutathione S-transferase theta (GSTT1): cDNA cloning and the characterization of a genetic polymorphism. Biochem J 1994: 300, 271-276.
14. Smith G, Stanley LA, Sim E, Strange RC, Wolf CK. Metabolic polymorphisms and cancer susceptibility. Cancer Surv 1995: 25, 27-65.