Oral terbinafine in the treatment of toenail onychomycosis: North American multicenter trial

Journal of the American Academy of Dermatology

Volumn 37, Issue 5 I, 1997, Pages 740-745

  Drake, L A ^a   Shear, N H ^a   Arlette, J P ^a   Cloutier, R ^a   Danby, F W ^a   Elewski, B E ^a   Garnis Jones, S ^a   Giroux, J M ^a   Gratton, D ^a   Gulliver, W ^a   Hull, P ^a   Jones, H E ^a   Journet, M ^a   Krol, A L ^a   Leyden, J J ^a   Maddin, S C ^a   Ross, J B ^a   Savin, R C ^a   Scher, R K ^a   Sibbald, G R ^a   Tawfik, N H ^a   Zaias, N ^a   Tolpin, M ^a   Evans, S ^a   Marsolais, C ^a   Chin, T ^a   Lin, T H ^a   Maher, T ^a   Birnbaum, J E ^a   more..

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FUNGICIDE; TERBINAFINE;

ADULT; AGED; ARTICLE; BACKACHE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIARRHEA; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG SAFETY; FEMALE; FLATULENCE; HEADACHE; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; ONYCHOMYCOSIS; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RELAPSE; RHINITIS; UPPER RESPIRATORY TRACT INFECTION;

EID: 0030666538     PISSN: 01909622     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0190-9622(97)70111-7     Document Type: Article

References (15)

1. DT Roberts Prevalence of dermatophyte onychomycosis in the United Kingdom: results of an omnibus survey Br J Dermatol 126 Suppl 39 1992 23 27
2. J André G Achten Onychomycosis Int J Dermatol 26 1987 481 490
3. VV Villars TC Jones Special features of the clinical use of oral terbinafine in the treatment of fungal diseases Br J Dermatol 126 Suppl 39 1992 61 69
4. N Zaias L Serrano The successful treatment of finger Trichophyton rubrum onychomycosis with oral terbinafine Clin Exp Dermatol 14 1989 120 123
5. MJD Goodfield L Andrew EGV Evans Short term treatment of dermatophyte onychomycosis with terbinafine BMJ 304 1992 1151 1154
6. JG Van Der Schroeff PKS Cirkel MB Crijns A randomized treatment duration-finding study of terbinafine in onychomycosis Br J Dermatol 126 Suppl 39 1992 36 39
7. N Mantel W Haenszel Statistical aspect of the analysis of data from retrospective studies of disease J Natl Cancer Inst 22 1959 719 748
8. Onychomycosis and terbinafine Lancet 335 1990 636
9. HC Korting M Schäfer-Korting Is tinea unguium still widely incurable? Arch Dermatol 128 1992 243 248
10. RJ Hay YM Clayton WAD Griffiths PM Dowd A comparative double blind study of ketoconazole and griseofulvin in dermatophytosis Br J Dermatol 112 1985 691 696
11. NS Ryder The mechanism of action of terbinafine Clin Exp Dermatol 14 1989 98 100
12. AY Finlay Pharmacokinetics of terbinafine in the nail Br J Dermatol 126 Suppl 39 1992 28 32
13. J Faergemann H Zehender L Millerioux Levels of terbinafine in plasma, stratum corneum, dermis-epidermis (without stratum corneum), sebum, hair and nails during and after 250 mg terbinafine orally once daily for 7 and 14 days Clin Exp Dermatol 19 1994 121 126
14. YM Clayton Relevance of broad-spectrum and fungicidal activity of antifungals in the treatment of dermatomycoses Br J Dermatol 130 Suppl 43 1994 7 8
15. DJ Back JF Tjia SM Abel Azoles, allylamines and drug metabolism Br J Dermatol 126 Suppl 39 1992 14 18