Antigenic variation of core, NS3, and NS5 proteins among genotypes of hepatitis C virus

Journal of Clinical Microbiology

Volumn 35, Issue 12, 1997, Pages 3062-3070

  Neville, J A ^a   Prescott, L E ^a   Bhattacherjee, V ^a   Adams, N ^a   Pike, I ^b   Rodgers, B ^b   El Zayadi, A ^c   Hamid, S ^d   Dusheiko, G M ^e   Saeed, A A ^f   Haydon, G H ^a   Simmonds, P ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b Murex Biotech Ltd   (United Kingdom)

^c Cairo Liver Center   (Egypt)

^d AGA KHAN UNIVERSITY   (Pakistan)

^e ROYAL FREE HOSPITAL   (United Kingdom)

^f The General Directorate of Armed Forces Health Services   (Saudi Arabia)

Author keywords

[No Author keywords available]

Indexed keywords

CORE PROTEIN; HEPATITIS C ANTIGEN;

ANTIGENIC VARIATION; ARTICLE; ENZYME LINKED IMMUNOSORBENT ASSAY; GENOTYPE; HEPATITIS C; HEPATITIS C VIRUS; HUMAN; IMMUNOREACTIVITY; MAJOR CLINICAL STUDY; PRIORITY JOURNAL;

HEPATITIS C VIRUS; STAPHYLOCOCCUS PHAGE 3A;

EID: 0030666436     PISSN: 00951137     EISSN: None     Source Type: Journal    
DOI: 10.1128/jcm.35.12.3062-3070.1997     Document Type: Article

References (29)

1. Bhattacherjee, V., L. E. Prescott, I. Pike, B. Rodgers, H. Bell, A. R. Elzayadi, M. C. Kew, J. Conradie, C. K. Lin, H. Marsden, A. A. Saeed, D. Parker, P. L. Yap, and P. Simmonds. 1995. Use of NS-4 peptides to identify type-specific antibody to hepatitis C virus genotypes 1, 2, 3, 4, 5 and 6. J. Gen. Virol. 76:1737-1748.
2. Cerino, A., M. Bissolati, A. Cividini, A. Nicosia, M. Esumi, N. Hayashi, K. Mizuno, R. Slobbe, P. Oudshoorn, E. Silini, M. Asti, and M. U. Mondelli. 1997. Antibody responses to the hepatitis C virus E2 protein: relationship, to viraemia and prevalence in anti-HCV seronegative subjects. J. Med. Virol. 51:1-5.
3. Chamberlain, R., N. Adams, E. A. B. Mccruden, P. Simmonds, and R. M. Elliott. 1997. The complete genome sequence of hepatitis C virus type 4a. J. Gen. Virol. 78:1342-1347.
4. Chan, S.-W., F. McOmish, E. C. Holmes, B. Dow. J. F. Peutherer, E. Follett, P. L. Yap, and P. Simmonds. 1992. Analysis of a new hepatitis C virus type and its phylogenetic relationship to existing variants. J. Gen. Virol. 73:1131-1141.
5. Chan, S. W., P. Simmonds, F. McOmish, P. L. Yap, R. Mitchell, B. Dow, and E. Follett. 1991. Serological responses to infection with three different types of hepatitis C virus. Lancet 338:1391.
6. Chang, T. T., K. C. Young, Y. J. Yang, K. A. Lai, H. L. Wu, M. H. Wu, M. Y. Chen, X. Z. Lin, C. Y. Lin, and J. S. Shin. 1996. Incidence of post-transfusion hepatitis in Taiwan before and after introduction of anti-HCV testing. Liver 16:201-206.
7. Choo, Q. L. K. H. Richman, J. H. Han, K. Berger, C. Lee, C. Dong, C. Gallegos, D. Coit, R. Medina Selby, P. J. Barr, A. J. Weiner, D. W. Bradley, G. Kuo, and M. Houghton. 1991. Genetic organization and diversity of the hepatitis C virus. Proc. Natl. Acad. Sci. USA 88:2451-2455.
8. Claeys, H., A. Volckaerts, W. Mertens, Z. Liang, P. Fiten, and G. Opdenakker. 1995. Localization and reactivity of an immunodominant domain in the NS3 region of hepatitis C virus. J. Med. Virol. 45:273-281.
9. Courouce, A. M., N. Lemarrec, A. Girault, S. Ducamp, and N. Simon. 1994. Anti-hepatitis C virus (anti-HCV) seroconversion in patients undergoing hemodialysis: comparison of second- and third-generation anti-HCV assays. Transfusion 34:790-795.
10. Courouce, A. M., and J. Pillonel. 1996. Transfusion-transmitted viral infections. N. Engl. J. Med. 335:1609-1610.
11. Davidson, F., P. Simmonds, J. C. Ferguson, L. M. Jarvis, B. C. Dow, E. A. C. Follett, C. R. G. Seed, T. Krusius, C. Lin, G. A. Medgyesi, H. Kiyokawa, G. Olim, G. Duraisamy, T. Cuypers, A. A. Saeed, D. Teo, J. Conradie, M. C. Kew, M. Lin, C. Nuchaprayoon, O. K. Ndimbie, and P. L. Yap. 1995. Survey of major genotypes and subtypes of hepatitis C virus using RFLP of sequences amplified from the 5′ non-coding region. J. Gen. Virol. 76:1197-1204.
12. Dhaliwal, S. K., L. E. Prescott, B. C. Dow, F. Davidson, H. Brown, P. L. Yap, E. A. C. Follett, and P. Simmonds. 1996. Influence of viraemia and genotype upon serological reactivity in screening assays for antibody to hepatitis C virus. J. Med. Virol. 48:184-190.
13. Dixit, V., S. Quan, P. Martin, D. Larson, M. Brezina, R. Dinello, K. Sra, J. Y. N. Lau, D. Chien, J. Kolberg, A. Tagger, G. Davis, A. Polito, and G. Gitnick. 1995. Evaluation of a novel serotyping system for hepatitis C virus: strong correlation with standard genotyping methodologies. J. Clin. Microbiol. 33:2978-2983.
14. Dow, B. C., H. Munro, I. Buchanan, E. A. C. Follett, F. Davidson, P. L. Yap, and P. Simmonds. 1996. Third-generation recombinant immunoblot assay: comparison of reactivities according to hepatitis C virus genotype. Transfusion 36:547-551.
15. Gonzalez, A., J. I. Esteban, P. Madoz, L. Viladomiu, J. Genesca, E. Muniz, J. Enriquez, X. Torras, J. M. Hernandez, J. Quer. X. Vidal, H. J. Alter, J. W. Shin, R. Esteban, and J. Guardia. 1995. Efficacy of screening donors for antibodies to the hepatitis C virus to prevent transfusion-associated hepatitis: final report of a prospective trail. Hepatology 22:439-445.
16. Jarvis, L. M., H. G. Watson, F. McOmish, J. F. Peutherer, C. A. Ludlam, and P. Simmonds. 1994. Frequent reinfection and reactivation of hepatitis C virus genotypes in multitransfused hemophiliacs. J. Infect. Dis. 170:1018-1022.
17. Kao, J. H., M. Y. Lai, Y. T. Hwang, P. M. Yang, P. J. Chen, J. C. Sheu, T. H. Wang, H. C. Hsu, and D. S. Chen. 1996. Chronic hepatitis C without anti-hepatitis C antibodies by second-generation assay: a clinicopathologic study and demonstration of the usefulness of a third-generation assay. Dig. Dis. Sci. 41:161-165.
18. Lelie, P. N., H. T. M. Cuypers, H. W. Reesink, C. L. van der Poel, I. Winkel, E. Bakker, P. J. Vanexeloehlers, D. Vallari, J. P. Allain, and L. Mimms. 1992. Patterns of serological markers in transfusion-transmitted hepatitis-C virus infection using 2nd-generation HCV assays. J. Med. Virol. 37:203-209.
19. Machida, A., H. Ohnuma, F. Tsuda, E. Munekata, T. Tanaka, Y. Akahane, H. Okamoto, and S. Mishiro. 1992. Two distinct subtypes of hepatitis C virus defined by antibodies directed to the putative core protein. Hepatology 16:886-891.
20. Makris, K., V. Kouvelis, I. Drakopoulos, E. Oikonomou, and A. Maniatis. 1995. Frequency and characteristics of post-transfusion hepatitis in Greece with emphasis on hepatitis C: comparing second- and third-generation assays. Transfus. Med. 5:213-224.
21. McOmish, F., S.-W. Chan, B. C. Dow, J. Gillon, W. D. Frame, R. J. Crawford, P. L. Yap, E. A. C. Follett, and P. Simmonds. 1993. Detection of three types of a C virus in blood donors: investigation of type-specific differences in serological reactivity and rate of alanine aminotransferase abnormalities. Transfusion 33:7-13.
22. Mondelli, M. U., A. Cerino, F. Bono, A. Cividini, A. Maccabruni, M. Aricò, A. Malfitano, G. Barbarini, V. Piazza, L. Minoli, and E. Silini. 1995. Hepatitis C virus (HCV) core serotypes in chronic HCV infection. J. Clin. Microbiol. 32:2523-2527.
23. Prescott, L. E., A. Berger, J. M. Pawlotsky, P. Conjeevaram, I. Pike, and P. Simmonds. Sequence analysis of hepatitis C virus variants producing discrepant results with two different genotyping assays. J. Med. Virol., in press.
24. Schreiber, G. B., M. P. Busch, S. H. Kleinman, and J. J. Korelitz. 1996. The risk of transfusion-transmitted viral infections. N. Engl. J. Med. 334:1685-1690.
25. Simmons, P., F. McOmish, P. L. Yap, S. W. Chan, C. K. Lin, G. Dusheiko, A. A. Saeed, and E. C. Holmes. 1993. Sequence variability in the 5′ non coding region of hepatitis C virus: identification of a new virus type and restrictions on sequence diversity. J. Gen. Virol. 74:661-668.
26. Simmonds, P., K. A. Rose, S. Graham, S. W. Han, F. McOmish, B. C. Dow, E. A. C. Follett, P. L. Yap, and H. Marsden. 1993. Mapping of serotype-specific, immunodominant epitopes in the NS-4 region of hepatitis C virus (HCV): use of type-specific peptides to serologically differentiate infections with HCV type 1, type 2, and type 3. J. Clin. Microbiol. 31:1493-1503.
27. Takano, S., K. Nakamura, s. Kawai, O. Yokosuka, Y. Satomura, and M. Omata. 1996. Prospective assessment of donor blood screening for antibody to hepatitis C virus by first- and second-generation assays as a means of preventing posttransfusion hepatitis. Hepatology 23:708-712.
28. Zein, N. N., J. Rakela, and D. H. Persing. 1995. Genotype-dependent serologic reactivities in patients infected with hepatitis C virus in the United States. Mayo Clin. Proc. 70:449-452.
29. Zhang, Z. X., Z. B. Yun, M. Chen, A. Sonnerborg, and M. Sallberg. 1995. Evaluation of a multiple peptide assay for typing of antibodies to the hepatitis C virus: relation to genomic typing by the polymerase chain reaction. J. Med. Virol. 45:50-55.