Synthesis, physical and biological properties of lithocholyl-lysyl-fluorescein: A fluorescent monohydroxy bile salt analogue with cholestatic properties

Biochimica et Biophysica Acta - General Subjects

Volumn 1336, Issue 3, 1997, Pages 485-496

  Mills, Charles O ^a   Milkiewicz, Piotr ^a   Molloy, David P ^b   Baxter, Debbie J ^c   Elias, Elwyn ^a  

^a Wolfson Research Laboratories   (United Kingdom)

^b UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^c LIVERPOOL JOHN MOORES UNIVERSITY   (United Kingdom)

Author keywords

Cholestasis; Fluorescent monohydroxy bile salt; Lithocholyl lysyl fluorescein; Rat

Indexed keywords

BILE SALT; FLUORESCEIN DERIVATIVE; GLYCOLITHOCHOLIC ACID; LITHOCHOLIC ACID; LITHOCHOLIC ACID GLUCURONIDE; LITHOCHOLYLLYSYLFLUORESCEIN; SULFOLITHOCHOLIC ACID; TAUROCHOLIC ACID; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BILE FLOW; CHOLESTASIS; CONTROLLED STUDY; DRUG HALF LIFE; DRUG SOLUBILITY; DRUG SYNTHESIS; FLUORESCENCE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; INTRAVENOUS DRUG ADMINISTRATION; MALE; MICELLE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PARTITION COEFFICIENT; PLASMA CLEARANCE; PRIORITY JOURNAL; RAT; STRUCTURE ACTIVITY RELATION;

ANIMALS; BILE; BILE ACIDS AND SALTS; CHOLESTASIS; FLUORESCEINS; GLUCURONATES; INDICATORS AND REAGENTS; LITHOCHOLIC ACID; LYSINE; MALE; MOLECULAR STRUCTURE; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; RATS; RATS, WISTAR; SOLUBILITY;

ANIMALIA; FISTULA; MALUS X DOMESTICA;

EID: 0030665703     PISSN: 03044165     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-4165(97)00063-9     Document Type: Article

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