Reducing cell membrane n-6 fatty acids attenuate mucosal damage in food- sensitive enteropathy in mice

Pediatric Research

Volumn 42, Issue 6, 1997, Pages 835-839

  Ohtsuka, Yoshikazu ^a,b   Yamashiro, Yuichiro ^a   Shimizu, Toshiaki ^a   Nagata, Satoru ^a   Igarashi, Jun ^a   Shinohara, Kouichi ^a   Oguchi, Satoshi ^a   Yabuta, Keijiro ^a  

^a JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LEUKOTRIENE; OMEGA 6 FATTY ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD VESSEL PERMEABILITY; CELL DAMAGE; CELL MEMBRANE; CONTROLLED STUDY; DIETARY INTAKE; ENTEROPATHY; ERYTHROCYTE MEMBRANE; FOOD ALLERGY; HYPERSENSITIVITY; INTESTINE MUCOSA; LIPID COMPOSITION; MALABSORPTION; MOUSE; NONHUMAN; PRIORITY JOURNAL;

EID: 0030665226     PISSN: 00313998     EISSN: None     Source Type: Journal    
DOI: 10.1203/00006450-199712000-00019     Document Type: Article

References (25)

1. Phillips AD, Rice SJ, France NE, Walker-Smith JA 1979 Small intestinal intraepithelial lymphocyte levels in cow's milk protein intolerance. Gut 20:509-512
2. MacDonald TT, Spencer J 1988 Evidence that activated mucosal T cells play a role in the pathogenesis of enteropathy in human small intestine. J Exp Med 167:1341-1349
3. Ebert EC 1990 Intra-epithelial lymphocytes: interferon-γ production and suppressor/ cytotoxic activities. Clin exp Immunol 82:81-85
4. Branski D, Eran M, Sharon P, Gross-Kieselstein E, Weidenfeld J, Freier S 1987 Rise of prostanoids in rat small intestinal mucosa following intestinal protein hypersensitivity. Pediatr Res 21:414-416
5. 4 cause widespread and extensive plasma extravasation in the guinea pig. Arch Pharmacol 330:136-141
6. 4 on ileal ion transport in vitro in the rat and rabbit. Am J Physiol 255:G175-G183
7. 4 in the intestine. Hepatogastroenterology 35:87-90
8. 4 in atopic dermatitis: increased skin levels and altered sensitivity of peripheral blood T-cells. Allergy 45:457-463
9. Branski D, Hurvitz H, Halevi A, Klar A, Navon P, Weidenfeld J 1992 Eicosanoids content in small intestinal mucosa of children with celiac disease. J Pediatr Gastroenterol Nutr 14:173-176
10. 4 generation by small intestinal mucosa in children with coeliac disease. Digestion 55:239-242
11. 4 by colonic mucosa in inflammatory bowel disease. Gastroenterology 86:453-460
12. Hawthorne AB, Filipowicz BL, Edwards TJ, Hawkey CJ 1990 High dose eicosapentaenoic acid ethyl ether: effects on lipids and neutrophil leukotriene production in normal volunteers. Br J Clin Pharmacol 30:187-194
13. Stenson WF, Cort D, Rodger J, Burakoff R, DeSchryver-Kecskemeti K, Gramlich TL, Beeken W 1992 Dietary supplementation with fish oil in ulcerative colitis. Ann Inter Med 116:609-614
14. Ikehata A, Hiwatashi N, Kinouchi Y, Yamazaki H, Kumagai Y, Ito K, Kayaba Y, Toyota T 1992 Effect of intravenously infused eicosapentaenoic acid on the leukotriene generation in patients with active Crohn's disease. Am J Clin Nutr 56:938-942
15. Hawthorne AB, Daneshmend TK, Hawkey CJ, Belluzzi A, Everitt SJ, Holmes GK, Milkinson C, Shaheen MZ, Willars JE 1992 Treatment of ulcerative colitis with fish oil supplementation: a prospective 12 month randomized controlled trial. Gut 33:922-928
16. Mowat AM, Ferguson A 1981 Hypersensitivity in the small intestinal mucosa. Clin Exp Immunol 43:574-582
17. Ohtsuka Y, Yamashiro Y, Maeda M, Oguchi S, Shimizu T, Nagata S, Yagita H, Yabuta K, Okumura K 1996 Food antigen activate intraepithelial and lamina propria lymphocytes in food-sensitive enteropathy in mice. Pediatr Res 39:862-866
18. Burton GW, Ingold KV, Thompson KE 1981 An improved procedure for the isolation of ghost membranes from human red blood cells. Lipids 16:12-13
19. Jimenez J, Boza J, Suarez MD, Gil A 1992 Change in fatty acid profiles of red blood cell membranes mediated by dietary nucleotides in weaning rats. J Pediatr Gastroenterol Nutr 14:293-299
20. Odlander B, Claesson HE 1987 A rapid and sensitive method for measurement of leukotrienes based on HPLC. Biomed Chromatogr 2:145-147
21. Hrboticky N, MacKinnon MJ, Innis SM 1990 Effect of a vegetable oil formula rich in linoleic acid on tissue fatty acid accretion in the brain, liver, plasma, and erythrocytes of infant piglets. Am J Clin Nutr 51:173-182
22. Levy JA, Ibrahim AB, Shirai T, Ohta K, Nagasawa R, Yoshida H, Estes J, Gardner M 1982 Dietary fat affects immune response, production of antiviral factors, and immune complex disease in NZB/NZW mice. Proc Natl Acad Sci USA 79:1974-1978
23. 1 mice. J Immunol 135:3857-3863
24. 1 mice. J Immunol 135:3864-3868
25. Kitsukawa Y, Saito H, Suzuki Y, Kasanuki J, Tamura Y, Yoshida S 1992 Effect of ingestion of eicosapentaenoic acid ethyl ester on carrageenan-induced colitis in guinea pig. Gastroenterology 102:1859-1866