C/EBPα and C/EBPβ play similar roles in the transcription of the human Cu/Zn SOD gene

Gene

Volumn 203, Issue 1, 1997, Pages 11-15

  Seo, Seong Jin ^a   Kang, Sang Sun ^a   Cho, Ginam ^a   Rho, Hyune Mo ^a   Jung, Guhung ^a  

^a Res Ctr Cell Differentiation   (South Korea)

Author keywords

C EBP; Promoter; Sp1; Superoxide dismutase; Transcription

Indexed keywords

COPPER ZINC SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR;

ARTICLE; CONTROLLED STUDY; GENE ACTIVATION; GENE EXPRESSION; GENETIC TRANSCRIPTION; HUMAN; PRIORITY JOURNAL; PROMOTER REGION; REGULATOR GENE; TRANSCRIPTION REGULATION;

CCAAT-ENHANCER-BINDING PROTEINS; COPPER; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; NUCLEAR PROTEINS; PROMOTER REGIONS (GENETICS); RECOMBINANT FUSION PROTEINS; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTORS; TUMOR CELLS, CULTURED; ZINC;

EID: 0030664111     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1119(97)00484-8     Document Type: Article

References (23)

1. Birkenmeier E.H., Gwynn B., Howard S., Jerry J., Gordon J.I., Landschulz W.H., McKnight S.L. Tissue-specific expression, developmental regulation and genetic mapping of the gene encoding CCAAT/enhancer binding protein. Genes Dev. 3:1989;1146-1156.
2. Cao Z., Umek R.M., McKnight S.L. Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells. Genes Dev. 5:1991;1538-1552.
3. Chomczynski P., Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:1987;156-159.
4. Cooper C., Henderson A., Artandi S., Avitahl N., Calame K. Ig/EBP (C/EBP gamma) is a transdominant negative inhibitor of C/EBP family transcriptional activators. Nucleic Acids Res. 23:1995;4371-4377.
5. Crapo J.D., Oury T., Rabouile C., Slot J.W., Chang L.-Y. Cu, Zn superoxide dismutase is primarily a cytosolic protein in human cells. Proc. Natl. Acad. Sci. USA. 89:1992;10405-10409.
6. Descombes P., Schibler U. A liver-enriched transcriptional activator protein, LAP, and a transcriptional inhibitory protein, LIP, are translated from the same mRNA. Cell. 67:1991;569-579.
7. Dynan W.S., Tjian R. The promoter-specific transcription factor Sp1 binds to upstream sequences in the SV40 early promoter. Cell. 35:1983;79-87.
8. Friedman A.D., Landschulz W.H., McKnight S.L. CCAAT/enhancer binding protein activates the promoter of the serum albumin gene in cultured hepatoma cells. Genes Dev. 3:1989;1314-1322.
9. Galeotti T., Wohlrab H., Borrello S., De Leo M.E. Messenger RNA for manganese and copper-zinc superoxide dismutases in hepatomas: correlation with degree of differentiation. Biochem. Biophys. Res. Commun. 165:1989;581-589.
10. Gergel D., Misik V., Ondrias K., Cederbaum A.I. Increased cytotoxicity of 3-morpholinosydnonimine to HepG2 cells in the presence of superoxide dismutase. Role of hydrogen peroxide and iron. J. Biol. Chem. 270:1995;20922-20929.
11. Gorman C.M., Moffat L.F., Howard B.H. Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells. Mol. Cell. Biol. 2:1982;1044-1051.
12. Kadonaga J.T., Carner K.R., Masiarz F.R., Tjian R. Isolation of cDNA encoding transcription factor Sp1 and functional analysis of the DNA binding domain. Cell. 51:1987;1079-1090.
13. Kayanoki Y., Fujii J., Suzuki K., Kawata S., Matsuzawa Y., Taniguchi N. Suppression of antioxidative enzyme expression by transforming growth factor-beta 1 in rat hepatocytes. J. Biol. Chem. 269:1994;15488-15492.
14. Kim Y.H., Yoo H.Y., Chan M.S., Jung G., Rho H.M. C/EBP alpha is a major activator for the transcription of rat Cu/Zn superoxide dismutase gene in liver cell. FEBS Lett. 401:1997;267-270.
15. Landschulz W.H., Johnson P.F., McKnight S.L. The DNA binding domain of the rat liver nuclear protein C/EBP is bipartite. Science. 243:1989;1681-1688.
16. Montesano L., Carri M.T., Mariottini P., Amaldi F., Rotilio G. Developmental expression of Cu, Zn superoxide dismutase in Xenopus. Constant level of the enzyme in oogenesis and embryogenesis. Eur. J. Biochem. 186:1989;421-426.
17. Peled-Kamar M., Lotem J., Okon E., Sachs L., Groner Y. Thymic abnormalities and enhanced apoptosis of thymocytes and bone marrow cells in transgenic mice overexpressing Cu/Zn-superoxide dismutase. Implications for Down syndrome. EMBO J. 14:1995;4985-4993.
18. Ron D., Habener J. CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription. Genes Dev. 6:1992;439-453.
19. Sambrook, J., Fritsch, E.F., Maniatis, T., 1989. Molecular Cloning. A Laboratory Manual, 2nd edn. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
20. Scott M.D., Meshnick S.R., Eaton J.W. Superoxide dismutase-rich bacteria. Paradoxical increase in oxidant toxicity. J. Biol. Chem. 262:1987;3640-3645.
21. Seo S.J., Kim H.T., Cho G., Rho H.M., Jung G. Sp1 and C/EBP-related factor regulate the transcription of human Cu/Zn SOD gene. Gene. 178:1996;177-180.
22. Vinson C.R., Hai T., Boyd S.M. Dimerization specificity of the leucine zipper-containing bZIP motif of DNA binding prediction and rational design. Genes Dev. 7:1993;1047-1058.
23. Williams S.C., Cantwell C.A., Johnson P.F. A family of C/EBP-related proteins capable of forming covalently linked leucine zipper dimers in vitro. Genes Dev. 5:1991;1553-1567.