Interleukin-12 p40 m-RNA expression in human kidney allograft biopsies

Transplant Immunology

Volumn 5, Issue 3, 1997, Pages 199-203

  De Mattos, Angelo M ^a   Meyer, Mary M ^b   Norman, Douglas J ^a   Bennett, William M ^b   Sprague, Jerald ^a   Bakee, Antony C ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b Mail Code PP262   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 12; MESSENGER RNA;

AUTORADIOGRAPHY; CLINICAL ARTICLE; CONFERENCE PAPER; HISTOLOGY; HUMAN; HUMAN TISSUE; KIDNEY ALLOGRAFT; KIDNEY ALLOGRAFT REJECTION; KIDNEY BIOPSY; KIDNEY FIBROSIS; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 0030664069     PISSN: 09663274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0966-3274(97)80038-X     Document Type: Conference Paper

References (34)

1. Kobayashi M, Fitz L, Ryan M, et al. Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes. J Exp Med. 170:1989;827-845.
2. D'Andrea A, Rengaraju M, Valiante NM, et al. Production of natural killer cell stimulatory factor (interleukin 12) by peripheral blood mononuclear cells. J Exp Med. 176:1992;1387-1398.
3. Podlaski FJ, Nanduri VB, Hulmes JD, et al. Molecular characterization of interleukin 12. Arch Biochem Biophys. 294:1992;230-237.
4. Gubler U, Chua AO, Schoenhaut DS, et al. Co-expression of two distinct genes is required to generate secreted bioactive cytotoxic lymphocyte maturation factor. Proc Natl Acad Sci USA. 88:1991;4143-4147.
5. Chizzonite R, Truitt T, Podlaski FJ, et al. IL-12: monoclonal antibodies specific for the 40-kDa subunit block receptor binding and biologic activity on activated human lymphoblasts. J Immunol. 147:1991;1548-1556.
6. Wolf SF, Temple PA, Kobayashi M, et al. Cloning of cDNA for natural killer cell stimulatory factor, a heterodimeric cytokine with multiple biologic effects on T and natural killer cells. J Immunol. 146:1991;3074-3081.
7. Desai BB, Quinn PM, Wolitzky AG, Mongini PKA, Chizzonite R, Gately MK. IL-12 receptor: II. Distribution and regulation of receptor expression. J Immunol. 148:1992;3125-3132.
8. Manetti R, Parronchi P, Giudizi MG, et al. Natural killer cell stimulatory factor (interleukin 12 (IL-12) induced T helper Type 1 (Th1)-specific immune responses and inhibits the development of IL-4 producing Th cells. J Exp Med. 177:1993;1199-1204.
9. Gately MK, Desai BB, Wolitzky AG, et al. Regulation of human lymphocyte proliferation by a heterodimeric cytokine, IL-12 (cytotoxic lymphocyte maturation factor). J Immunol. 147:1991;874-882.
10. Sieling PA, Wang X-H, Gately MK, et al. IL-12 regulates T helper type 1 cytokine responses in human infectious disease. J Immunol. 153:1994;3639-3647.
11. Clerici M, Lucey DR, Berzofsky JA, et al. Restoration of HIV-specific cell-mediated immune responses by interleukin-12 in vitro. Science. 262:1993;1721-1724.
12. Hall SS. IL-12 holds promise against cancer, glimmer of AIDS hope. Science. 263:1994;1685-1686.
13. Chehimi J, Valiante N, Pinto LA, et al. Enhancing effect of natural killer cell stimulatory factor (NKSF/interleukin-12) on cell-mediated cytotoxicity against tumor-derived and virus-infected cells. Eur J Immunol. 23:1993;1826-1830.
14. Heinrich MC, Dooley DC, Freed AC, et al. Constitutive expression of steel factor gene by human stromal cells. Blood. 82:1993;771-783.
15. Rigby PWJ, Dieckmann M, Rhodes C, Berg P. Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I. J Mol Biol. 113:1977;237-251.
16. Suthanthiran M, Strom TB. Renal transplantation. N Engl J Med. 331:1994;365-376.
17. Dallman MJ, Roake J, Hughes D, Toogood G, Morris PJ. Sequential analysis of IL-2 gene transcription in renal transplants. Transplantation. 53:1992;683-685.
18. Williamson P, Allen RDM, Chapman JR, Stewart GJ. Analysis of mRNA in renal allografts using polymerase chain reaction amplification. Transplantation Proc. 24:1992;205-207.
19. Tovey MG, Deglise-Favre A, Schoevaert D. Differential in situ expression of cytokine genes in human renal transplantation. Kidney Int. 43:1993;S-129-S-132. (suppl 39).
20. Bertagnolli MM, Lin B-Y, Young D, Herrmann SH. IL-12 augments antigens-dependent proliferation of activated T lymphocytes. J Immunol. 149:1992;3778-3783.
21. Lu CY, Sicher SC, Vazquez MA. Prevention and treatment of renal allograft rejection: new therapeutic approaches and new insights into established therapies. JASN. 4:1993;1239-1256.
22. Nickoloff BJ, Turka LA. Immunological functions of non-professional antigen-presenting cells: new insights from studies of T cell interactions with keratinocytes. Immunol Today. 15:1994;464-469.
23. Lisley PS, Brady W, Grosmaire L, Aruffo A, Damle NK, Ledbetter JA. Binding of the B cell activation antigen B7 to CD28 costimulates T cell proliferation and interleukin 2 mRNA accumulation. J Exp Med. 173:1991;721-730.
24. Kubin M, Kamoun M, Trinchieri G. Interleukin 12 synergizes with B7/CD28 interaction in inducing efficient proliferation and cytokine production of human T cells. J Exp Med. 180:1994;211-222.
25. Murphy EE, Terres G, Macatonia SE, et al. B7 and interleukin 12 cooperate for proliferation and gamma interferon production by mouse T helper clones that are unresponsive to B7 costimulation. J Exp Med. 180:1994;223-231.
26. Trinchieri G, Rengaraju M, D'Andrea A, et al. Producer cells of interleukin-12. Immunol today. 14:1993;237-238.
27. Yard BA, Kooymans-Couthino M, Reterink T, et al. Analysis of T cell lines from rejecting renal allografts. Kidney Int. 43:1993;S-133-S-138. (suppl 39).
28. Merville P, Pouteil-Noble C, Wijdenes J, Potaux L, Touraine J, Banchereau J. Detection of single cells secreting IFN-gamma, IL-6, and IL-10 in irreverisbly rejected human kidney allografts, and their modulation by IL-2 and IL-4. Transplantation. 55:1993;639-646.
29. Kirk AD, Ibrahim MA, Bollinger RR, Dawson DV, Finn OJ. Renal allograft-infiltrating lymphocytes. Transplantation. 53:1992;329-338.
30. Scott P. IL-12: initiation cytokine for cell-mediated immunity. Science. 260:1993;496-497.
31. Tilney NL, Schmid C, Azuma H, Heemann UW. Transplantation immunology: an introduction. Transpl Immunol. 2:1994;99-102.
32. Heemann UW, Tullius SG, Tamatami T, Miyasaka M, Milford EL, Tilney NL. Infiltration patterns of macrophages and lymphocytes in chronically rejecting rat kidney allografts. Transpl Int. 7:1994;346-355.
33. Mattner F, Fischer S, Guckes S, et al. The interleukin-12 subunit p40 specifically inhibits effects of the interleukin-12 heterodimer. Eur J Immunol. 23:1993;2202-2208.
34. + IFN-gamma-producing cells. J Immunol. 158:1997;643-648.