External monitoring of cerebral nicotinic acetylcholine receptors in living mice

Synapse

Volumn 27, Issue 4, 1997, Pages 378-380

  Liu, Xiang ^a   Musachio, John L ^a   Wagner Jr , Henry N ^a   Mochizuki, Takao ^a   Dannals, Robert F ^a   London, Edythe D ^b  

^a DEPARTMENT OF PATHOLOGY   (United States)

^b NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 IODO 5 PYRIDYL) 7 AZABICYCLO[2,2,1]HEPTANE; BRAIN RECEPTOR; CYTISINE; EPIBATIDINE; IODINE 125; NICOTINIC RECEPTOR; SODIUM CHLORIDE; TRACER; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; INTRAVENOUS DRUG ADMINISTRATION; MALE; MONITORING; MOUSE; NONHUMAN; PRIORITY JOURNAL; RADIOACTIVITY; RECEPTOR AFFINITY;

ANALYSIS OF VARIANCE; ANIMALS; BRAIN; FEASIBILITY STUDIES; IODINE RADIOISOTOPES; MALE; MICE; MICE, INBRED STRAINS; MOLECULAR STRUCTURE; RECEPTORS, NICOTINIC;

EID: 0030663984     PISSN: 08874476     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2396(199712)27:4<378::AID-SYN11>3.0.CO;2-O     Document Type: Article

References (8)

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2. 125I]IPH, an epibatidine analog, binds with high affinity to neuronal nicotinic cholinergic receptors. J. Pharmacol. Exp. Ther. 282:445-451.
3. Gerzanich, V., Peng, X., Wang, F., Wells, G., Anand, R., Fletcher, S., and Lindstrom, J. (1995) Comparative pharmacology of epibatidine: A potent agonist for neuronal nicotinic acetylcholine receptors. Mol. Pharmacol., 48:774.
4. 3H] epibatidine binding to nicotinic cholinergic receptors in rat and human brain. Mol. Pharmacol., 48:280-287.
5. 3H]epibatidine. Eur. J. Pharmacol., 278:R1-R2.
6. Musachio, J.L., Horti, A., London, E.D., and Dannals, R.F. (1997) Synthesis of a radioiodinated analog of epibatidine: (+)-exo-2-(2-iodo-5-pyridyl)-7-azabicyclo[2.2.1]heptane for in vitro and in vivo studies of nicotinic acetylcholine receptors. J. Labelled Compd. Radiopharma., 39:39-48.
7. 125I]-4-iodolevetimide. Neuropharmacology, 32:1441-1443.
8. Wada, E., Wada, K., Boulter, J., Deneris, E., Heinemann, S., Patrick, J., and Swanson, L.W. (1989) Distribution of alpha2, alpha3, alpha4, and beta2 neuronal nicotinic receptor subunit mRNAs in the central nervous system: A hybridization histochemical study in the rat. J. Comp. Neurol., 284:314-335.