Total synthesis of Nephilatoxin-1 (NPTX-1), a Joro spider (Nephila clavata) toxin having a 4-hydroxyindole nucleus

Tetrahedron Letters

Volumn 38, Issue 48, 1997, Pages 8297-8298

  Miyashita, Masaaki ^a   Saito, Hiroaki ^a   Matsushita, Masayuki ^a   Miyazawa, Masahiro ^a   Itagaki, Yasuhiro ^b   Nakajima, Terumi ^b  

^a HOKKAIDO UNIVERSITY   (Japan)

^b SUNTORY INSTITUTE FOR BIOORGANIC RESEARCH   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

1 (3 DIMETHYLAMINOPROPYL) 3 ETHYLCARBODIIMIDE; 9 FLUORENYLMETHYL CHLOROFORMATE; ASPARAGINE; AZIDE; BENZOTRIAZOLE DERIVATIVE; CADAVERINE; DIMETHYL SULFOXIDE; ETHYLAMINE; INDOLE DERIVATIVE; N,N DIMETHYLFORMAMIDE; NEPHILATOXIN; SPERMIDINE; SPIDER VENOM; UNCLASSIFIED DRUG;

ARTICLE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROGENATION; MASS SPECTROMETRY; NEUROTRANSMISSION; POLYMERIZATION; TOXIN STRUCTURE; TOXIN SYNTHESIS;

ARANEAE; NEPHILA CLAVATA;

EID: 0030663745     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(97)10205-2     Document Type: Article

References (13)

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13. 3OD) δ: 7.05 (s, 1H), 6.93 (dd, J=8.2, 6.5 Hz, 1H), 6.90 (dd, J=8.2, 1.9 Hz, 1H), 6.41 (dd, J=6.5, 1.9 Hz, 1H), 4.66 (t, J=6.3 Hz, 1H), 3.86 (d, J=15.3 Hz, 1H), 3.79 (d, J=15.3 Hz, 1H), 2.78-3.35 (m, 14 H), 2.68 (d, J=6.3 Hz, 2H), 2.52 (t, J=6.3 Hz, 2H), 1.98-2.15 (m, 2H), 1.69-1.85 (m, 4H), 1.20-1.43 (m, 4H), 1.10 (qui, J=7.1 Hz, 2H).