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Volumn 14, Issue 10, 1997, Pages 747-754

Hirudin suppresses the invasion of inflammatory cells and the appearance of vimentin-positive astrocytes in the rat cerebral ablation model

Author keywords

Hirudin; Reactive astrocyte; Reactive gliosis; Thrombin; Trauma

Indexed keywords

ANTICOAGULANT AGENT; GELFOAM; GLIAL FIBRILLARY ACIDIC PROTEIN; HEPARIN; LEPIRUDIN; PROTHROMBIN; SERINE PROTEINASE; SODIUM CHLORIDE; THROMBIN; THROMBIN INHIBITOR; VIMENTIN;

EID: 0030663651     PISSN: 08977151     EISSN: None     Source Type: Journal    
DOI: 10.1089/neu.1997.14.747     Document Type: Article
Times cited : (18)

References (34)
  • 1
    • 0026662747 scopus 로고
    • Effect of thrombin on proliferation, contraction and prostaglandin production of rat glomerular mesangial cells in culture
    • ALBRIGHTSON, C.R., NAMBI, P., ZABKO, P.B., DYTKO, G., and GROOM, T. (1992). Effect of thrombin on proliferation, contraction and prostaglandin production of rat glomerular mesangial cells in culture. J. Pharmacol. Exp. Ther. 263, 404-12.
    • (1992) J. Pharmacol. Exp. Ther. , vol.263 , pp. 404-412
    • Albrightson, C.R.1    Nambi, P.2    Zabko, P.B.3    Dytko, G.4    Groom, T.5
  • 2
    • 0024365681 scopus 로고
    • Vimentin-GFAP transition in primary dissociated cultures of rat embryo spinal cord
    • BIGNAMI, A., and DAHL, D. (1989). Vimentin-GFAP transition in primary dissociated cultures of rat embryo spinal cord. Int. J. Devl. Neurosci. 7, 343-357.
    • (1989) Int. J. Devl. Neurosci. , vol.7 , pp. 343-357
    • Bignami, A.1    Dahl, D.2
  • 3
    • 0025255579 scopus 로고
    • Reciprocal modulation of astrocytes stellation by thrombin and protease nexin 1
    • CAVANAUGH, K.P., GURWITZ, D., CUNNINGHAM, D.D., and BRADSHAW, R.A. (1990). Reciprocal modulation of astrocytes stellation by thrombin and protease nexin 1. J. Neurochem. 54, 1735-1743.
    • (1990) J. Neurochem. , vol.54 , pp. 1735-1743
    • Cavanaugh, K.P.1    Gurwitz, D.2    Cunningham, D.D.3    Bradshaw, R.A.4
  • 4
    • 0021780387 scopus 로고
    • The heterogeneity of mononuclear phagocytes in lymphoid organs: Distinct macrophage subpopulations in rat recognized by monoclonal antibodies ED1, ED2 and ED3
    • DIJKSTRA, C.D., DOPP, E.A., JOLING, P., and KRAAL, G. (1985). The heterogeneity of mononuclear phagocytes in lymphoid organs: distinct macrophage subpopulations in rat recognized by monoclonal antibodies ED1, ED2 and ED3. Adv Exp Med Biol. 186, 409-19.
    • (1985) Adv Exp Med Biol , vol.186 , pp. 409-419
    • Dijkstra, C.D.1    Dopp, E.A.2    Joling, P.3    Kraal, G.4
  • 6
    • 0028284811 scopus 로고
    • Specific thrombin inhibitors in vivo
    • FITZGERALD, D. (1994). Specific thrombin inhibitors in vivo. Ann NY Acad Sci. 714, 41-52.
    • (1994) Ann NY Acad Sci , vol.714 , pp. 41-52
    • Fitzgerald, D.1
  • 7
    • 0022506166 scopus 로고
    • Synthesis and secretion of nerve growth factor by mouse astroglial cells in culture
    • FURUKAWA, S., FURUKAWA, Y., SATOYOSHI, E., and HAYASHI, K. (1986). Synthesis and secretion of nerve growth factor by mouse astroglial cells in culture. Biochem Biophys Res commun. 136, 57-63.
    • (1986) Biochem Biophys Res Commun , vol.136 , pp. 57-63
    • Furukawa, S.1    Furukawa, Y.2    Satoyoshi, E.3    Hayashi, K.4
  • 8
    • 0026697339 scopus 로고
    • Effect of spontaneous pathology and thrombin on leukocyte adhesion to rat aortic endothelium
    • GABALDON, M., CAPDEVILA, C., and ZUNIGA, A. (1992). Effect of spontaneous pathology and thrombin on leukocyte adhesion to rat aortic endothelium. Atherosclerosis 93, 217-28.
    • (1992) Atherosclerosis , vol.93 , pp. 217-228
    • Gabaldon, M.1    Capdevila, C.2    Zuniga, A.3
  • 9
    • 0011811083 scopus 로고
    • Thrombin modulates and reverses neuroblastoma neurite outgrowth. (protease nexin-1/glial-derived neurite promoting factor/heparin/hirudin)
    • GURWITZ, D., and CUNNINGHAM, D.D. (1988). Thrombin modulates and reverses neuroblastoma neurite outgrowth. (protease nexin-1/glial-derived neurite promoting factor/heparin/hirudin). Proc. Natl. Acad. Sci. USA. 85, 3440-3444.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 3440-3444
    • Gurwitz, D.1    Cunningham, D.D.2
  • 10
    • 0025189336 scopus 로고
    • Neurite out growth activity of protease nexin-1 on neuroblastoma cells requires thrombin inhibition
    • GURWITZ, D., and CUNNINGHAM, D.D. (1990). Neurite out growth activity of protease nexin-1 on neuroblastoma cells requires thrombin inhibition. J. Cell Physiol. 142, 155-162.
    • (1990) J. Cell Physiol. , vol.142 , pp. 155-162
    • Gurwitz, D.1    Cunningham, D.D.2
  • 11
    • 0023038272 scopus 로고
    • a-Thrombin induces release of platelet-derived growth factor-like molecule(s) by cultured human endothelial cells
    • HARLAN, J.M., THOMPSON, P.J., ROSS, R.R., and BOWEN-POPE, D.F. (1986). a-Thrombin induces release of platelet-derived growth factor-like molecule(s) by cultured human endothelial cells. J Cell Biol. 103, 1129-1133.
    • (1986) J Cell Biol. , vol.103 , pp. 1129-1133
    • Harlan, J.M.1    Thompson, P.J.2    Ross, R.R.3    Bowen-Pope, D.F.4
  • 12
    • 0028027007 scopus 로고
    • Thrombin induces endothelial cell growth via both a proteolytic and a non-proteolytic pathway
    • HERBERT, J.M., DUPUY, E., LAPLACE, M.C., ZINI, J.M., BAR, S.R., and TOBELEM, G. (1994). Thrombin induces endothelial cell growth via both a proteolytic and a non-proteolytic pathway. Biochem. J. 303, 227-231.
    • (1994) Biochem. J. , vol.303 , pp. 227-231
    • Herbert, J.M.1    Dupuy, E.2    Laplace, M.C.3    Zini, J.M.4    Bar, S.R.5    Tobelem, G.6
  • 13
    • 0026748742 scopus 로고
    • Thrombin receptor activation causes rapid neural cell rounding and neurite retraction independent of classic second messengers
    • JALINK, K., and MOOLENAAR, W.H. (1992). Thrombin receptor activation causes rapid neural cell rounding and neurite retraction independent of classic second messengers. J. Cell Biol. 118, 411-9.
    • (1992) J. Cell Biol. , vol.118 , pp. 411-419
    • Jalink, K.1    Moolenaar, W.H.2
  • 14
    • 0026289512 scopus 로고
    • Lesion-induced proliferation of vimentin-positive astrocytes in the mouse cerebral hemisphere
    • JANECZKO, K. (1991). Lesion-induced proliferation of vimentin-positive astrocytes in the mouse cerebral hemisphere. Folia Histochem. Cytobiol. 29, 55-58.
    • (1991) Folia Histochem. Cytobiol. , vol.29 , pp. 55-58
    • Janeczko, K.1
  • 15
    • 0028283508 scopus 로고
    • Hirudin: Clinical potential of a thrombin inhibitor
    • JOHNSON, P.H. (1994). Hirudin: clinical potential of a thrombin inhibitor. Annu. Rev. Med. 45, 165-77.
    • (1994) Annu. Rev. Med. , vol.45 , pp. 165-177
    • Johnson, P.H.1
  • 16
    • 0025133268 scopus 로고
    • Thrombin and factor Xa enhance the production of interleukin-1
    • JONES, A., and GECZY, C.L. (1990). Thrombin and factor Xa enhance the production of interleukin-1. Immunology 71, 236-241.
    • (1990) Immunology , vol.71 , pp. 236-241
    • Jones, A.1    Geczy, C.L.2
  • 17
    • 0023925077 scopus 로고
    • Transcriptional regulation of the A and B chain genes of platelet derived growth factor in microvascular endothelial cells
    • KAVANAUGH, W.M., HARSH, G.R.I., STARKSEN, N.F., ROCCO, C.M., and WILLIAMS, L.T. (1988). Transcriptional regulation of the A and B chain genes of platelet derived growth factor in microvascular endothelial cells. J. Biol. Chem. 263, 8470-8472.
    • (1988) J. Biol. Chem. , vol.263 , pp. 8470-8472
    • Kavanaugh, W.M.1    Harsh, G.R.I.2    Starksen, N.F.3    Rocco, C.M.4    Williams, L.T.5
  • 18
    • 0024383352 scopus 로고
    • Differential phenotypic expression induced in cultured rat astroblasts by acidic fibroblast growth factor, epidermal growth factor and thrombin
    • LORET, C., SENSENBRENNER, M., and LABOURDETTE, G. (1989). Differential phenotypic expression induced in cultured rat astroblasts by acidic fibroblast growth factor, epidermal growth factor and thrombin. J. Biol Chem. 264, 8319-8327.
    • (1989) J. Biol Chem. , vol.264 , pp. 8319-8327
    • Loret, C.1    Sensenbrenner, M.2    Labourdette, G.3
  • 19
    • 0027492461 scopus 로고
    • Thrombin stimulates proliferation of cultured rat aortic smooth muscle cells by a proteolytically activated receptor
    • MCNAMARA, C.A., SAREMBOCK, I.J., GIMPLE, L.W., FENTON, J. 2., COUGHLIN, S.R., and OWENS, G.K. (1993). Thrombin stimulates proliferation of cultured rat aortic smooth muscle cells by a proteolytically activated receptor [see comments]. J. Clin. Invest. 91, 94-8.
    • (1993) J. Clin. Invest. , vol.91 , pp. 94-98
    • Mcnamara, C.A.1    Sarembock, I.J.2    Gimple, L.W.3    Fenton II, J.4    Coughlin, S.R.5    Owens, G.K.6
  • 20
    • 0027326873 scopus 로고
    • Thrombin may contribute to the pathophysiology of central nervous system injury
    • NISHINO, A., SUZUKI, M., OHTANI, H., et al. (1993). Thrombin may contribute to the pathophysiology of central nervous system injury. J. Neurotrauma 10, 167-79.
    • (1993) J. Neurotrauma , vol.10 , pp. 167-179
    • Nishino, A.1    Suzuki, M.2    Ohtani, H.3
  • 21
    • 0026605497 scopus 로고
    • Light and electron microscopic immunolocalization of endothelial leukocyte adhesion molecule-1 (ELAM-1) in inflammatory bowel disease: Morphological evidence of active synthesis and secretion into vascular lumen
    • OHTANI, H., NAKAMURA, S., and WATANABE, Y. (1992). Light and electron microscopic immunolocalization of endothelial leukocyte adhesion molecule-1 (ELAM-1) in inflammatory bowel disease: Morphological evidence of active synthesis and secretion into vascular lumen. Virchows Arch [A]. 420, 403-409.
    • (1992) Virchows Arch [A] , vol.420 , pp. 403-409
    • Ohtani, H.1    Nakamura, S.2    Watanabe, Y.3
  • 22
    • 0023517177 scopus 로고
    • Thrombin is a potent mitogen for rat astroblasts but not for oligodendroblasts in primary culture
    • PERRAUD, F., BESNARD, F., SENSENBRENNER, M., and LABOURDETTE, G. (1987). Thrombin is a potent mitogen for rat astroblasts but not for oligodendroblasts in primary culture. Int. J. Devl. Neuroscience 5, 181-188.
    • (1987) Int. J. Devl. Neuroscience , vol.5 , pp. 181-188
    • Perraud, F.1    Besnard, F.2    Sensenbrenner, M.3    Labourdette, G.4
  • 24
    • 0028062029 scopus 로고
    • Specific heparin fractions suppress endothelin-1 production in cultured human umbilical vein endothelial cells
    • REANTRAGOON, S., ARRIGO, L.M., SEOUD, M.M., DWECK, H.S., and ROSENFELD, L. (1994). Specific heparin fractions suppress endothelin-1 production in cultured human umbilical vein endothelial cells. Arch. Biochem. Biophys. 314, 315-22.
    • (1994) Arch. Biochem. Biophys. , vol.314 , pp. 315-322
    • Reantragoon, S.1    Arrigo, L.M.2    Seoud, M.M.3    Dweck, H.S.4    Rosenfeld, L.5
  • 25
    • 0022512360 scopus 로고
    • Glial fibrillary acidic protein and vimentin in the experimental glial reaction of the rat brain
    • SCHIFFER, D., GIORDANA, M.T., MIGHELI, A., GIACCONE, G., PEZZOTTA, S., and MAURO, A. (1986). Glial fibrillary acidic protein and vimentin in the experimental glial reaction of the rat brain. Brain Res. 374, 110-118.
    • (1986) Brain Res. , vol.374 , pp. 110-118
    • Schiffer, D.1    Giordana, M.T.2    Migheli, A.3    Giaccone, G.4    Pezzotta, S.5    Mauro, A.6
  • 26
    • 0026786440 scopus 로고
    • 3-Deazaadenosine inhibits thrombin-stimulated platelet-derived growth factor production and endothelial-leukocyte adhesion molecule-1-mediated monocytic cell adhesion in human aortic endothelial cells
    • SHANKAR, R., DE LA MOTTE, C.A., and DICORLETO, P.E. (1992). 3-Deazaadenosine inhibits thrombin-stimulated platelet-derived growth factor production and endothelial-leukocyte adhesion molecule-1-mediated monocytic cell adhesion in human aortic endothelial cells. J. Biol. Chem. 267, 9376-82.
    • (1992) J. Biol. Chem. , vol.267 , pp. 9376-9382
    • Shankar, R.1    De La Motte, C.A.2    Dicorleto, P.E.3
  • 27
    • 0022478424 scopus 로고
    • The origin of osteoclasts: An immunohistochemical study on macrophages and osteoclasts in embryonic rat bone
    • SMINIA, T., and DIJKSTRA, C.D. (1986). The origin of osteoclasts: an immunohistochemical study on macrophages and osteoclasts in embryonic rat bone. Calcif. Tissue Int. 39, 263-6.
    • (1986) Calcif. Tissue Int. , vol.39 , pp. 263-266
    • Sminia, T.1    Dijkstra, C.D.2
  • 28
    • 0022542997 scopus 로고
    • The macrophage population of the gastro-intestinal tract of the rat
    • SMINIA, T., and JEURISSEN, S.H. (1986). The macrophage population of the gastro-intestinal tract of the rat. Immunobiology 172, 72-80.
    • (1986) Immunobiology , vol.172 , pp. 72-80
    • Sminia, T.1    Jeurissen, S.H.2
  • 29
    • 0022510265 scopus 로고
    • Rat thymus macrophages: An immunohistochemical study on fetal, neonatal and adult thymus
    • SMINIA, T., VAN ASSELT, A.A., VAN DE ENDE, M.B., and DIJKSTRA, C.D. (1986). Rat thymus macrophages: an immunohistochemical study on fetal, neonatal and adult thymus. Thymus 8, 141-50.
    • (1986) Thymus , vol.8 , pp. 141-150
    • Sminia, T.1    Van Asselt, A.A.2    Van De Ende, M.B.3    Dijkstra, C.D.4
  • 30
    • 0023864095 scopus 로고
    • Immunohistochemical studies on the proliferation of reactive astrocytes and the expression of cytoskeletal proteins following brain injury in rats
    • TAKAMIYA, Y., KOHSAKA, S., TOYA, S., OHTANI, M., and TSUKADA, Y. (1988). Immunohistochemical studies on the proliferation of reactive astrocytes and the expression of cytoskeletal proteins following brain injury in rats. Brain Res. 466, 201-210.
    • (1988) Brain Res. , vol.466 , pp. 201-210
    • Takamiya, Y.1    Kohsaka, S.2    Toya, S.3    Ohtani, M.4    Tsukada, Y.5
  • 31
    • 0025338919 scopus 로고
    • Thrombin reverts the b-adrenergic agonist-induced morphological response in rat glioma C6 cells
    • TAS, P.W.L., and KOSCHEL, K. (1990). Thrombin reverts the b-adrenergic agonist-induced morphological response in rat glioma C6 cells. Exp. Cell Res. 189, 22-27.
    • (1990) Exp. Cell Res. , vol.189 , pp. 22-27
    • Tas, P.W.L.1    Koschel, K.2
  • 32
    • 0028214577 scopus 로고
    • Distinct receptors and signaling pathways in alpha-thrombin- and thrombin receptor peptide-induced vascular contractions
    • TESFAMARIAM, B. (1994). Distinct receptors and signaling pathways in alpha-thrombin- and thrombin receptor peptide-induced vascular contractions. Circ Res. 74, 930-6.
    • (1994) Circ Res. , vol.74 , pp. 930-936
    • Tesfamariam, B.1
  • 33
    • 0021806352 scopus 로고
    • Characterization of pulmonary macrophages and bronchus-associated lymphoid tissue (BALT) macrophages in the rat. An enzyme-cytochemical and immunocytochemical study
    • VAN DER BRUGGE GAMELKOORN, G., DIJKSTRA, C.D., and SMINIA, T. (1985). Characterization of pulmonary macrophages and bronchus-associated lymphoid tissue (BALT) macrophages in the rat. An enzyme-cytochemical and immunocytochemical study. Immunobiology. 169, 553-62.
    • (1985) Immunobiology , vol.169 , pp. 553-562
    • Van Der Brugge Gamelkoorn, G.1    Dijkstra, C.D.2    Sminia, T.3
  • 34
    • 0028124564 scopus 로고
    • Retention and relearning of spatial delayed alternation in rats after ablation of the prefrontal or total non-prefrontal isocortex
    • WOERTWEIN, G., MOGENSEN, J., and DIVIC, I. (1994). Retention and relearning of spatial delayed alternation in rats after ablation of the prefrontal or total non-prefrontal isocortex. Behav. Brain Res. 63, 127-131.
    • (1994) Behav. Brain Res. , vol.63 , pp. 127-131
    • Woertwein, G.1    Mogensen, J.2    Divic, I.3


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