CNS sequelae in Langerhans cell histiocytosis: Progressive spinocerebellar degeneration as a late manifestation of the disease

Pediatric Hematology and Oncology

Volumn 14, Issue 6, 1997, Pages 577-584

  Cervera, Aurea ^a,b   Madero, Luis ^a   García Peñas, Juan J ^a   Díaz, Miguel Angel ^a   Gutiérrez Solana, Luis G ^a   Benito, Ana ^a   Ruiz Falcó, Mari Luz ^a   Villa, Marta ^a  

^a HOSPITAL INFANTIL UNIVERSITARIO NIÑO JESÚS   (Spain)

^b HOSPITAL DE MÓSTOLES   (Spain)

Author keywords

Central nervous system; Cerebellum; Langerhans cell histiocytosis

Indexed keywords

ADOLESCENT; ARTICLE; CASE REPORT; CELL INFILTRATION; COMPUTER ASSISTED TOMOGRAPHY; DIABETES INSIPIDUS; DISEASE COURSE; FEMALE; HISTIOCYTOSIS X; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPOTHALAMUS; LANGERHANS CELL; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; SCHOOL CHILD; SPINOCEREBELLAR DEGENERATION;

EID: 0030662323     PISSN: 08880018     EISSN: None     Source Type: Journal    
DOI: 10.3109/08880019709030915     Document Type: Article

References (20)

1. Berry DH, Bedon DL. Natural history of histiocytosis-X. Hematol Oncol Clin North Am. 1987;1:23-34.
2. Fujisawa I, Nishimura K, Asato R, et al. Posterior lobe of the pituitary in diabetes insipidus: MR findings. J Comput Assist Tomogr. 1987;11:221-225.
3. Broadbent V, Dunger DB, Yeomans E, Kendall B. Anterior pituitary function and computed tomography/magnetic resonance imaging in patients with Langerhans cell histiocytosis and diabetes insipidus. Med Pediatr Oncol. 1993;21:646-654.
4. Grois N, Barkovich JA, Rosenau W, Ablin AR. Central nervous system disease associated with Langerhans' cell histiocytosis. Am J Pediatr Hematol Oncol. 1993;15:245-254.
5. Komp DM, El Mahdi A, Starling KA, et al. Quality of survival in histiocytosis-X: a Southwest Oncology Group study. Med Pediatr Oncol. 1980;8:35-40.
6. Hasegawa K, Mitomi T, Kowa H, Motoori T, Yagisita S. A clinico-pathological study of adult histiocytosis X involving the brain. J Neurol Neursurg Psychiatry. 1993;56:1008-1012.
7. Reznik M, Stevenaert A, Bex V, Kratzenberg E. Focal brain invasion as the first manifestation of Langerhans cell histiocytosis in an adult. Clin Neuropathol. 1993;12:179-183.
8. Hammar S, Weaver RA, Keranen VJ. Left temporal lobe cerebral cortex mass in a 19 year old male. Ultrastruct Pathol. 1986;10:583-591.
9. Hamilton B, Connolly ES, Mitchell WT, Isolated intramedullary hisliocytosis-X of the cervical spinal cord. J Neurosurg. 1995;83:716-718.
10. Grois N, Tsunematsu Y, Barkovich J, Favara BE. Central nervous system disease in Langerhans cell histiocytosis. Br J Cancer Suppl. 1994;79:S24-S25.
11. Goldberg-Stern H, Weitz R, Zaizov R, Gornish M, Gadoth N. Progressive spinocerebellar degeneration "plus" associated with Langerhans cell histiocytosis: a new paraneoplastic syndrome? J Neurol Neurosurg Psychiatry. 1995;58:180-183.
12. Amirdjazil Z, Serban-Aurel E, Konard K. Histiocytosis X in an adult with skin and uncommon central nervous system involvement. Dermatologica. 1977;155:283-291.
13. Rosenfield NS, Abrahams J, Komp D. Brain MR in patients with Langerhans cell histiocytosis: findings and enhancement with Gd-DTPA. Pediatr Radiol. 1990;20 433-436.
14. Strottmann JM, Ginsberg LE, Stanton C. Langerhans cell histiocytosis involving the corpus callosum and cerebellum: gadolinium-enhanced MRI. Neuroradiology. 1995;37:289-292.
15. Hayward J, Packer R, Finley J. Central nervous system and Langerhans cell histiocytosis. Med Pediatr Oncol. 1990;18:325-328.
16. Braunstein GD, Whitaker JN, Kohler PO. Cerebellar dysfunction in Hand-Schüller-Christian disease. Arch Intern Med. 1973;132:387-390.
17. Adornato BT. Eil C, Head GL, Loriaux LD. Cerebellar involvement in multifocal eosinophilic granuloma: demonstration by computerized tomographic scanning. Ann Neurol. 1980;7:125-129.
18. Favara BE, Jaffe R. The histopathology of Langerhans cell histiocytosis. Br J Cancer Suppl. 1994;70: S17-S23.
19. Durack DT, Sumi SM, Klebanoff JS, Neurotoxicity of human eosinophils. Proc Natl Acad Sci USA. 1979;76:1443-1447.
20. Gadner H, Heitger A, Grois N, Gatterer-Menz I, Ladish S. Treatment strategy for disseminated Langerhans cell histiocytosis. Med Pediatr Oncol. 1994;23:72-80.