A new attachment/cleavage strategy: Polymer-bound allylic sulfones in a solid-phase route to trisubstituted olefins

Tetrahedron Letters

Volumn 38, Issue 44, 1997, Pages 7709-7712

  Halm, Chris ^a   Evarts, Jerry ^a   Kurth, Mark J ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALKENE; ALLYL COMPOUND; POLYMER; POLYSTYRENE; RESIN; SULFONE DERIVATIVE;

ALKYLATION; ARTICLE; CHEMICAL MODIFICATION; DERIVATIZATION; SYNTHESIS;

EID: 0030659432     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(97)10062-4     Document Type: Article

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21. 13C-HMR, IR, and MS. Isolated yields are as reported and crude product purities were >80%.
22. The loading of sulfinate on the polymer was calculated by titration of sulfinic acid by NaOH in THF (0.3 meq/g). Allylation gave polymer-bound allyl sulfone with approximately 0.3 meq./g (ASTM E 441-90).