Inherited abnormalities of blood coagulation in juvenile stroke. A case- control study

Blood Coagulation and Fibrinolysis

Volumn 8, Issue 7, 1997, Pages 397-402

  Tosetto, A ^a   Ruggeri, M ^a   Castaman, G ^a   Rodeghiero, F ^a  

^a SAN BORTOLO HOSPITAL   (Italy)

Author keywords

Antithrombin; Heparin cofactor II; Plasminogen; Protein C; Protein S; Stroke

Indexed keywords

ANTITHROMBIN; HEPARIN COFACTOR II; PLASMINOGEN; PROTEIN C; PROTEIN S;

ADOLESCENT; ADULT; ARTICLE; BLOOD CLOTTING DISORDER; CASE CONTROL STUDY; CEREBROVASCULAR ACCIDENT; CLINICAL ARTICLE; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; FAMILIAL DISEASE; FEMALE; HUMAN; MALE; PRIORITY JOURNAL; RISK FACTOR; THROMBOPHILIA; THROMBOSIS;

EID: 0030659094     PISSN: 09575235     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001721-199710000-00004     Document Type: Article

References (58)

1. Thorvaldsen P, Asplund K, Kuulasmaa K, Rajakangas A, Schroll M. Stroke incidence, case fatality, and mortality in the WHO MONICA Project. Stroke 1995; 26: 361-367.
2. Nencini P, Inzitari D, Baruffi MC, Fratiglioni L, Gagliardi R, Benvenuti L, et al. Incidence of stroke in young adults in Florence, Italy. Stroke 1988; 19: 977-981.
3. Hart RG, Kanter MC. Hematologic disorders and ischemic stroke. A selective review. Stroke 1990; 21: 1111-1121.
4. Coull BM, Clark WM. Abnormalities of hemostasis in ischemic stroke. Med Clin North Am 1993; 77: 77-94.
5. Arima T, Motomura M, Nishiura Y, Tsujihata M, Okajima K, Abe H, et al. Cerebral infarction in a heterozygote with variant antithrombin III. Stroke 1992; 23: 1822-1825.
6. Ernerudh J, Olsson JE, von Schenck H. Antithrombin-III deficiency in ischemic stroke. Stroke 1990; 21: 967.
7. Ueyama H, Hashimoto Y, Uchino M, Sasaki Y, Uyama E, Okajima K, et al. Progressing ischemic stroke in a homozygote with variant antithrombin III. Stroke 1989; 20: 815-818.
8. Deguchi K, Tsukada T, Iwasaki E, Wada H, Murashima S, Miyazaki M, et al. Late-onset homozygous protein C deficiency manifesting cerebral infarction as the first symptom at age 27. Intern Med 1992; 31: 922-925.
9. Grewal RP, Goldberg MA. Stroke in protein C deficiency [letter]. Am J Med 1990; 89: 538-539.
10. Kohler J, Kasper J, Witt I, von Reutern GM. Ischemic stroke due to protein C deficiency. Stroke 1990; 21: 1077-1080.
11. Haire WD, Newland JR. Protein C deficiency and anticardiolipin antibodies in a family with premature stroke. Am J Hematol 1990; 33: 61-63.
12. Devilat M, Toso M, Morales M. Childhood stroke associated with protein C or S deficiency and primary antiphospholipid syndrome. Pediatr Neurol 1993; 9: 67-70.
13. Matsushita K, Kuriyama Y, Sawada T, Uchida K. Cerebral infarction associated with protein C deficiency. Stroke 1992; 23: 108-111.
14. Camerlingo M, Finazzi G, Casto L, Laffranchi C, Barbui T, Mamoli A. Inherited protein C deficiency and nonhemorrhagic arterial stroke in young adults. Neurology 1991; 41: 1371-1373.
15. Kuzui S, Kuriyama Y, Sakata T, Hiroki M, Miyashita K, Sawada T. Accelerated brain infarction in hypertension complicated by hereditary heterozygous protein C deficiency. Stroke 1993; 24: 2097-2103.
16. Davous P, Horellou MH, Conard J, Samama M. Cerebral infarction and familial protein S deficiency. Stroke 1990; 21: 1760-1761.
17. Green D, Otoya J, Oriba H, Rovner R. Protein S deficiency in middle-aged women with stroke. Neurology 1992; 42: 1029-1033.
18. Israels SJ, Seshia SS. Childhood stroke associated with protein C or S deficiency. J Pediatr 1987; 111: 562-564.
19. Sacco RL, Owen J, Mohr JP, Tatemichi TK, Grossman BA. Free protein S deficiency: a possible association with cerebrovascular occlusion. Stroke 1989; 20: 1657-1661.
20. Brown DC, Livingston JH, Minns RA, Eden OB. Protein C and S deficiency causing childhood stroke. Scott Med J 1993; 38: 114-115.
21. Barinagarrementeria F, Cantu-Brito C, Izaguirre R, De La Pena A. Progressive intracranial occlusive disease associated with deficiency of protein S. Report of two cases. Stroke 1993; 24: 1752-1756.
22. Nagayama T, Shinohara Y, Nagayama M, Tsuda M, Yamamura M. Congenitally abnormal plasminogen in juvenile ischemic cerebrovascular disease. Stroke 1993; 24: 2104-2107.
23. Halbmayer W, Hanshofer A, Schon R, Fischer M. The prevalence of poor anticoagulant response to activated protein C (APC resistance) among patients suffering from stroke or venous thrombosis and among healthy subjects. Blood Coag Fibrinol 1994; 5: 51-57.
24. Simioni P, de Ronde H, Prandoni P, Saladini M, Bertina R, Girolami A. Ischemic stroke in young patients with activated protein C resistance. A report of three cases belonging to three different kindreds. Stroke 1995; 26: 885-890.
25. Ganesan V, Kelsey H, Cookson J, Osborn A, Kirkham FJ. Activated protein C resistance in childhood stroke. Lancet 1996; 347: 260.
26. De Lucia D, Cerbone AM, Belli A, Di Mauro C, Renis V, Conte M, et al. Resistance to activated protein C in adults with a history of juvenile transient ischemic attacks. Thromb Haemost 1996; 76: 627-628.
27. Barinagarrementeria F, Cantu-Brito C, De La Pena A, Izaguirre R. Prothrombotic states in young people with idiopathic stroke. A prospective study. Stroke 1994; 25: 287-290.
28. Mayer SA, Sacco RL, Hurlet-Jensen A, Shi T, Mohr JP. Free protein S deficiency in acute ischemic stroke. A case-control study. Stroke 1993; 24: 224-227.
29. Muir KW, Squire IB, Alwan W, Lees KR. Anti-cardiolipin antibodies in an unselected stroke population. Lancet 1994; 344: 452-456.
30. Nencini P, Baruffi MC, Abbate R, Massai G, Amaducci L, Inzitari D. Lupus anticoagulant and anti-cardiolipin antibodies in young adults with cerebral ischemia. Stroke 1992; 23: 189-193.
31. Dolan G, Forsyth PD. Activated protein C resistance in cases of cerebral infarction. Lancet 1995; 345: 795.
32. Kontula K, Ylikorkala A, Miettinen H, Vuorio A, Kauppinen-Makelin R, Hamalainen L, et al. Arg506Gln Factor V (Factor V Leiden) in patients with ischaemic cerebrevascular disease and survivors of myocardial infarction. Thromb Haemost 1995; 73: 558-560.
33. Ridker PM, Hennekens CH, Lindpaintner K, Stampfer MJ, Eisenberg PR, Miletich JP. Mutation in the gene coding for coagulation Factor V and the risk of myocardial infarction, stroke, and venous thrombosis in apparently healthy men. N Engl J Med 1995; 332: 912-917.
34. Rose GA. The diagnosis of ischemic heart pain and intermittent claudication in field surveys. Bull WHO 1962; 27: 645-658.
35. The ARIC Investigators. The Atherosclerosis Risk In Communities (ARIC) study: design and objectives. Am J Epidemiol 1989; 129: 687-702.
36. Frezzato M, Tosetto A, Rodeghiero F. Validated questionnaire for the identification of previous personal or familial venous thromboembolism. Am J Epidemiol 1996; 143: 1257-1265.
37. Rodeghiero F, Tosetto A. The VITA Project: population-based distribution of protein C, antithrombin III, heparin cofactor II and plasminogen. Relationship with physiological variables and establishment of reference ranges. Thromb Haemost 1996; 76: 226-233.
38. Kahn HA, Sempos CT. Statistical Methods in Epidemiology. Oxford: Oxford University Press, 1989.
39. Rossi E, Mondonico P, Lombardi A, Preda L. Method for the determination of functional (clottable) fibrinogen by the new family of ACL coagulometers. Thromb Res 1988; 52: 453-468.
40. Tosetto A, Rodeghiero F. Diagnosis of APC resistance in patients on oral anticoagulant therapy. Thromb Haemost 1995; 73: 732-733.
41. Tosetto A, Missiaglia E, Gatto E, Rodeghiero F. The Vita Project: phenotypic resistance to activated protein C and FV Leiden mutation in the general population. Thromb Haemost 1997; 78: 859-863.
42. Hubbard AR. Standardization of protein C in plasma: establishment of an international standard. Thromb Haemost 1988; 59: 464-467.
43. Afifi AA, Clark VA. Computer-aided Multivariate Analysis. London: Chapman & Hall, 1990.
44. Kleinbaum DG, Kupper LL, Morgenstern H. Epidemiologic Research. Belmont, Calif: Lifetime Learning Publ., 1982.
45. StataCorp. Stata Statistical Software: Release 5.0, 1997.
46. Schafer AI. Hypercoagulable states: molecular genetics to clinical practice. Lancet 1994; 344: 1739-1742.
47. Rodeghiero F, Tosetto A. Some remarks on the epidemiology of thrombotic disorders. Thromb Haemost 1993; 69: 527-528.
48. Tosetto A, Gatto E, Rodeghiero F. Influence of cholesterol, triglycerides and fibrinogen on AT-III, PC, HC-II and plasminogen measurement. Thromb Haemost 1997; 77: 804.
49. Allaart CF, Rosendaal FR, Noteboom WM, Vandenbroucke JP, Briet E. Survival in families with hereditary protein C deficiency, 1820 to 1993. Br Med J 1995; 311: 910-913.
50. van Boven HH, Olds RJ, Thein SL, Reitsma PH, Lane DA, Briet E, et al. Hereditary antithrombin deficiency: heterogeneity of the molecular basis and mortality in Dutch families. Blood 1994; 84: 4209-4213.
51. Rosendaal FR, Heijboer H, Briet E, Buller HR, Brandjes DP, de Bruin K, et al. Mortality in hereditary antithrombin-III deficiency - 1830 to 1989. Lancet 1991; 337: 260-262.
52. Hille ET, Westendorp RG, Vandenbroucke JP, Rosendaal FR. Mortality and causes of death in families with the factor V Leiden mutation (resistance to activated protein C). Blood 1997; 89: 1963-1967.
53. De Stefano V, Leone G, Mastrangelo S, Tripodi A, Rodeghiero F, Castaman G, et al. Clinical manifestations and management of inherited thrombophilia: retrospective analysis and follow-up after diagnosis of 238 patients with congenital deficiency of antithrombin III, protein C, protein S. Thromb Haemost 1994; 72: 352-358.
54. Meade TW, Cooper J, Miller GJ, Howarth DJ, Stirling Y. Antithrombin III and arterial disease. Lancet 1991; 337: 850-851.
55. Cortellaro M, Boschetti C, Confrancesco E, Zanussi C, Catalano M, de Gaetano G, et al. The PLAT Study: hemostatic function in relation to atherothrombotic ischemic events in vascular disease patients: principal results. Arterioscler Thromb 1992; 12: 1063-1070.
56. Folsom AR, Wu KK, Shahar E, Davis CE. Association of hemostatic variables with prevalent cardiovascular disease and asymptomatic carotid artery atherosclerosis. Arterioscler Thromb 1993; 13: 1829-1836.
57. Fuster V, Badimon L, Badimon JJ, Chesebro JH. The pathogenesis of coronary artery disease and the acute coronary syndromes. N Engl J Med 1992; 326: 242-250.
58. Franken DG, Vreugdenhil A, Boers GH, Verrips A, Blom HJ, Novakova IR. Familial cerebrovascular accidents due to concomitant hyperhomocysteinemia and protein C deficiency type 1. Stroke 1993; 24: 1599-1600.