Mapping the inside of the ribosome with an RNA helical ruler

Science

Volumn 278, Issue 5340, 1997, Pages 1093-1098

  Joseph, Simpson ^a   Weiser, Bryn ^a   Noller, Harry F ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CROSS LINKING; DNA HELIX; EPITOPE MAPPING; GENE LOCATION; PRIORITY JOURNAL; RIBOSOME; RNA STRUCTURE; RNA TRANSLATION;

ANTICODON; BASE COMPOSITION; BASE SEQUENCE; EDETIC ACID; FERROUS COMPOUNDS; HYDROXYL RADICAL; MOLECULAR SEQUENCE DATA; NUCLEIC ACID CONFORMATION; ORGANOMETALLIC COMPOUNDS; RIBOSOMES; RNA PROBES; RNA, RIBOSOMAL; RNA, RIBOSOMAL, 16S; RNA, RIBOSOMAL, 23S; RNA, RIBOSOMAL, 5S; RNA, TRANSFER; RNA, TRANSFER, PHE;

EID: 0030657775     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.278.5340.1093     Document Type: Article

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65. We thank C. R. Woese for suggesting the internal calibration strategy; D. P. Greiner, J. Moran, and C. F. Meares for helping with synthesis of BABE and for providing samples of BABE used in early experiments; members of the Puglisi lab for providing T7 RNA polymerase; M.I. Recht for help with EXCEL; K. Lieberman and R. Green for discussions; and J. Cate, G. Culver, L. Newcomb, R. Green, K. Wilson, K. Lieberman, and L. Holmberg for review of the manuscript. Supported by grant GM-17129 from the NIH and from a grant to the Center for Molecular Biology of RNA from the Lucille P. Markey Charitable Trust.