Long-term results of total lymphoid irradiation in the treatment of cardiac allograft rejection

International Journal of Radiation Oncology Biology Physics

Volumn 39, Issue 5, 1997, Pages 953-960

  Wolden, Suzanne L ^a   Tate, David J ^a   Hunt, Sharon A ^a   Strober, Samuel ^a   Hoppe, Richard T ^a,b  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b STANFORD UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Cardiac transplant; Rejection; Total lymphoid irradiation

Indexed keywords

AZATHIOPRINE; CYCLOPHOSPHAMIDE; IMMUNOSUPPRESSIVE AGENT; METHOTREXATE; OKT 3; PREDNISONE; THYMOCYTE ANTIBODY;

ADOLESCENT; ADULT; ARTICLE; BONE MARROW SUPPRESSION; CLINICAL ARTICLE; FEMALE; GRAFT REJECTION; HEART TRANSPLANTATION; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; LYMPH NODE IRRADIATION; MALE; NONHODGKIN LYMPHOMA; ORGAN TRANSPLANTATION; PRIORITY JOURNAL; RADIATION DOSE; SPLEEN; T LYMPHOCYTE SUBPOPULATION; TREATMENT OUTCOME;

ADOLESCENT; ADULT; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CAUSE OF DEATH; CD4-CD8 RATIO; CHILD; CHILD, PRESCHOOL; FEMALE; FOLLOW-UP STUDIES; GRAFT REJECTION; HEART TRANSPLANTATION; HUMANS; INFANT; INFECTION; LYMPHATIC IRRADIATION; MALE; MIDDLE AGED; PREDNISONE; RADIOTHERAPY DOSAGE; THROMBOCYTOPENIA;

EID: 0030657739     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0360-3016(97)00504-X     Document Type: Article

References (39)

1. Bieber, C. P.; Jamieson, S.; Rainey, A.; Burton, N.; Bogarty, S.; Hoppe, R. T.; Kaplan, H. S.; Strober, S.; Stinson, E. B. Cardiac allograft survival in rhesus primates treated with combined total lymphoid irradiation and rabbit antithymocyte globulin. Transplantation 28:347-350; 1979.
2. Billingham, M. E.; Cary N. R. B.; Hammond, M. E.; Kemnitz, J.; Marboe, C.; McCallister, H. A.; Snovar, D. C.; Winters, G. L.; Zerbe, A. A Working formulatiion for the standardization of nomenclature in the diagnosis of heart and lung rejection: Heart Rejection Study Group. J. Heart Transplant. 9:587-593; 1990.
3. Chandler, C.; Passaro, E. Transplant rejection, mechanisms and treatment. Arch. Surg. 128:279-283; 1993.
4. Costanzo-Nordin, M. R.; O'Sullivan, J.; Hubbell, E. A.; Zucker, M. J.; Pifarre, R.; McManus, B. M.; Winters, G. L.; Scanlon, P. J.; Robinson, J. A. Long-term follow-up of heart transplant recipients treated with murine antihuman mature T cell monoclonal antibody (OKT3): The Loyola experience. J. Heart Transplant. 8:288-295; 1989.
5. Engleman, E. G.; Benike, C. J.; Hoppe, R. T.; et al. Autologous mixed lymphocyte reaction in patients with Hodgkin's disease: Evidence for a T-cell defect. J. Clin. Invest. 66:149; 1980.
6. Evans, B. A.; Schomberg, P. J.; Rodeheffer, R. J.; Katzman, J. A.; Schnell, W. A.; Tazelaar. H. D.; McGregor, C. G. A.; Edwards, B. S. Total lymphoid irradiation: A novel and successful therapy for resistant cardiac allograft rejection. Mayo Clin. Proc. 67:785-790; 1992.
7. Frist, W. H.; Biggs, V. J. Chronic myelogenous leukemia after lymphoid irradiation and heart transplantation. Ann. Thorac. Surg. 57:214-216; 1994.
8. Frist, W. H.; Winterlan, A. W.; Gerhardt, E. B.; Merrill, W. H.; Atkinson, J. B.; Eastburn, T. E.; Stewart, J. R.; Eisert, D. R. Total lymphoid irradiation in heart transplantation: Adjunctive treatment for recurrent rejection. Ann. Thorac. Surg. 48:863-864; 1989.
9. Fuks, Z.; Strober, S.; Bobrove, A. M.; Sasazuki, T.; Mc-Michael, A.; Kaplan, H. S. Long term effects of radiation on T and B lymphocytes in peripheral blood of patients with Hodgkin's disease. J. Clin. Invest. 58:803-814; 1976.
10. Halperin, E. C. Total lymphoid irradiation as an immunosuppressive agent for transplantation and the treatment of "autoimmune" disease: A review. Clin. Radiol. 36:125-130; 1985.
11. Halperin, E. C.; Knechtle, S. J.; Harland, R. C.; Yamaguchi, Y.; Sontag, M.; Bollinger, R. R. Irradiation for xenogeneic transplantation. Radiother. Oncol. 18:29-37; 1990.
12. Hancock, S. L.; Cox, R. S.; McDougall, I. R. Thyroid diseases after treatment of Hodgkin's disease. N. Engl. J. Med. 325: 599-605; 1991.
13. Hauptman, P. J.; Mechanick, J.; Lansman, S.; Gass, A. Fatal hyperthyroidism after amiodarone treatment and total lymphoid irradiation in a heart transplant recipient. J. Heart Lung Transplant. 12:513-516; 1993.
14. Herskowitz, A.; Soule, L. M.; Ueda, K.; Achuff, S. C.; Baumgartner, W. A.; Borkon, A. M.; Reitz, B. A.; Traill, T. A.; Baughman, K. L. Arteriolar vasculitis on endomyocardial biopsy: A histologic predictor of poor outcome in cyclosporin treated cardiac transplant recipients. Heart Transplant. 4:592; 1985.
15. Hosenpud, J. D.; Novick R. J.; Bennett, L. E.; Keck B. M.; Fiol B.; Daily, O. P. The Registry of the International Society for Heart and Lung Transplantation: Thirteenth official report - 1996. J. Heart Lung Transplant. 15:655-674; 1996.
16. Hunt, S. A.; Strober, S.; Hoppe, R. T.; Stinson, E. B. Total lymphoid irradition for treatment of intractable cardiac allograft rejection. J. Heart Lung Transplant. 10:211-216; 1991.
17. Janossy, G.; Tidman, N.; Selby, W. S.; Thomas, J. A.; Granger, S.; Kung, P. C.; Goldstein, G. Human T lymphocytes of inducer and suppressor type occupy different microenvironments. Nature 388:81-84; 1980.
18. Jarcho, J.; Naftel D. C.; Shroyer, T. W.; Kirklin, J. K.; Bourge, R. C.; Barr, M. L.; Pitts, D. G.; Starling, R. C.; The Cardiac Transplant Research Database Group. Influence of HLA mismatch on rejection after heart transplantation: A multiinstitutional study. J. Heart Lung Transplant. 13:583-596; 1994.
19. Kahn, D. R.; Hong, R.; Greenberg, A. J.; Gilbert, E. F.; Dacumos, G. C.; Dufek, J. H. Total lymphatic irradiation and bone marrow in human heart transplantation. Ann. Thorac. Surg. 38:160-171; 1984.
20. Kaplan, H. S. Hodgkin's disease, 2nd ed. Cambridge, MA: Harvard University Press; 1980.
21. Kirklin, J. K.; George, J. F.; McGriffin, D. C.; Naftel, D. C.; Salter, M. M.; Bourge, R. C. Total lymphoid irradiation: Is there a role in pediatric heart transplantation. J. Heart Lung Transplant. 12:S293-S300; 1993.
22. Kirklin, J. K.; Naftel, D. C.; McGiffin, D. C.; McVay. R. F.; Blackstone, E. H.; Karp, R. B. Analysis of morbid events and risk factors for death after cardiac transplantation. J. Am. Coll. Cardiol. 11:917-924; 1988.
23. Knechtle, S. J.; Halperin, E. C.; Bollinger, R. R. Xenograft survival in two species combinations using total lymphoid irradiation and cyclosporin. Transplantation. 43:173-175; 1987.
24. Koretz, S. H.; Gottlieb, M. S.; Strober, S.; Pennock, J.; Bieber, C P.; Hoppe, R. T.; Reitz, B. A.; Kaplan, H. S. Organ transplantation in mongrel dogs using total lymphoid irradiation (TLI). Transplant. Proc. 13:443-445; 1981.
25. Lauria, F.; Foa, R.; Gobbi, M.; Camaschella, C.; Lusso, P.; Raspadori, D.; Tura, S. Increased propertion of suppressor cytotoxic (OKT8 + ) cells in patients with Hodgkin's disease in long-lasting remission. Cancer 52:1385-1388; 1983.
26. Levin, B.; Bohannon, L.; Warvariv, V.; Bry, W.; Collins, G. Total lymphoid irradiation (TLI) in the cyclosporine era - Use of TLI in resistant cardiac allograft rejection. Transplant. Proc. 21:1793-1795; 1989.
27. Myburgh, J. A. Total lymphoid irradiation in transplantation. Transplant. Proc. 20:118-121; 1988.
28. Najarian, J. S.; Ferguson, R. M.; Sutherland, D. E.; Slavin, S.; Kim, T.; Kersey, K.; Simmonds, R. L. Fractionated total lymphoid irradiation as preparative immunosuppression in high-risk renal transplantation: Clinical and immunological studies. Ann. Surg. 196:442-452; 1982.
29. Opelz, G.; Henderson R.; for the Collaborative Transplant Study. Incidence of non-Hodgkin's lymphoma in kidney and heart transplant recipients. Lancet 342:1514-1516; 1993.
30. Pennock, J. L.; Reitz, B. A.; Bieber, C. P.; Aziz, S.; Oyer, P. E.; Strober, S.; Hoppe, R. T.; Kaplan, H. S.; Stinson, E. B.; Shumway, N. E. Survival of primates following orthotopic cardiac transplantation treated with total lymphoid irradiation and chemical immune suppression. Surgical Forum 32:467-473; 1981.
31. Rynasiewicz, J. J.; Sutherland, D. E. R.; Kawahara, R.; Najarian, J. S. Total lymphoid irradiation: Critical timing and combination with cyclosporin A for immunosuppression in a rat heart allograft model. J. Surg. Res. 30:365-371; 1981.
32. Salter, M. M.; Kirklin, J. K.; Bourge, R. C.; Naftel, D. C.; White-Williams, C.; Tarkka, M.; Waits, E.; Bucy, R. P. Total lymphoid irradiation in the treatment of early or recurrent heart rejection. J. Heart Lung Transplant. 11:902-911; 1992.
33. Salter, S. P.; Salter, M. M.; Kirklin, J. K.; Bourge, R. C.; Naftel, D. C. Total lymphoid irradiation in the treatment of early or recurrent heart transplant rejection. Int. J. Radiat. Oncol. Biol. Phys. 33:83-88; 1995.
34. Slavin, S.; Reitz, B.; Bieber, C. P.; Kaplan, H. S.; Strober, S. Transplantation tolerance in adult rats using total lymphoid irradiation: Permanent survival of skin, heart, and marrow allografts. J. Exp. Med. 147:700-707; 1978.
35. Slavin, S.; Strober, S.; Fuks, Z.; Kaplan, H. S. Long-term survival of skin allografts in mice treated with fractionated total lymphoid irradiation. Science 193:1252-1254; 1976.
36. Smith, S. H.; Kirklin, J. K.; Geer, J. C.; Caulfield, J. B.; McGiffin, D. C. Arteritis in cardiac rejection after transplantation. Am. J. Cardiol. 59:1171-1173; 1987.
37. Strober, S.; Modry, D. L.; Hoppe, R. T.; Pennock, J. L.; Bieber, C. P.; Holm, B. I.; Jamieson, S. W.; Stinson, E. B.; Schroder, J.; Suomalainen, H.; Kaplan, H. S. Induction of specific unresponsiveness to heart allografts in mongrel dogs treated with total lymphoid iradiation and anti-thymocyte globulin. J. Immunol. 132:1013-1017; 1984.
38. Swinnen, L. J.; Costanzo-Nordin, M. R.; Fisher, S. G.; O'Sullivan, E. J.; Johnson, M. R.; Heroux, A. L.; Dizikes, G. J.; Pifarre, R.; Fisher, R. I. Increased incidence of lymphoproliferative disorder after immunosuppression with the monoclonal antibody OKT3 in cardiac-transplant recipients. N. Eng J. Med. 323:1723-1728; 1990.
39. Tucker, M. A.; Coleman, C. N.; Cox, R. S., Varghese, A.; Rosenberg, S. A. Risk of second cancers after treatment for Hodgkin's disease. N. Engl. J. Med. 318:76-81; 1988.