Inhibition of shivering increases core temperature afterdrop and attenuates rewarming in hypothermic humans

Journal of Applied Physiology

Volumn 83, Issue 5, 1997, Pages 1630-1634

  Giesbrecht, Gordon G ^a   Goheen, M S L ^a   Johnston, C E ^a   Kenny, G P ^a   Bristow, Gerald K ^a   Hayward, John S ^b  

^a UNIVERSITY OF MANITOBA   (Canada)

^b UNIVERSITY OF VICTORIA   (Canada)

Author keywords

First aid; Hypothermia treatment; Rate of rewarming; Shivering thermogenesis

Indexed keywords

PETHIDINE;

ADULT; ARTICLE; CLINICAL PROTOCOL; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORE TEMPERATURE; DOSE RESPONSE; DRUG MECHANISM; FEMALE; HUMAN; HUMAN EXPERIMENT; HYPOTHERMIA; MALE; NONSHIVERING THERMOGENESIS; NORMAL HUMAN; PRIORITY JOURNAL; SHIVERING; WARMING;

EID: 0030657481     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/jappl.1997.83.5.1630     Document Type: Article

References (28)

1. Alexander, L. The Treatment of Shock From Prolonged Exposure to Cold, Especially in Water. Washington, DC: Office of Publ. Bd., Dept. of Commerce, 1946. (Combined Intelligence Objectives Subcommittee. Target 24. Rep. 250)
2. Bristow, G. K. Clinical aspects of accidental hypothermia. In: Living in the Cold. Physiological and Biochemical Adaptations, edited by C. Heller, X. J. Musacchia, and L. Wang. New York: Elsevier, 1985, p. 513-522.
3. Bristow, G. K., D. I. Sessler, and G. G. Giesbrecht. Leg temperature and heat content in humans during immersion hypothermia and rewarming. Aviat. Space Environ. Med. 65: 220-226, 1994.
4. Burton, A. C., and O. G. Edholm. Hypothermia and resuscitation. In: Man in a Cold Environment. London: Arnold, 1955, p. 200-222.
5. Collis, M. L., A. M. Steinman, and R. D. Chaney. Accidental hypothermia: an experimental study of practical rewarming methods. Aviat. Space Environ. Med. 48: 625-632, 1977.
6. Cooper, K. E., H. M. Ferres, J. R. Kenyon, and F. Wendt. A comparison of oesophageal, rectal and para-aortic temperatures during hypothermia in man. Br. J. Surg. 44: 616-619, 1957.
7. Delaunay, L., F. Bonnet, N. Liu, L. Beydon, P. Catoire, and D. I. Sessler. Clonidine comparably decreases the thermoregulatory threshold for vasoconstriction and shivering in humans. Anesthesiology 79: 470-474, 1993.
8. Durnin, J. V. G. A., and J. Womersley. Body fat assessed from total body density and its estimation from skinfold thickness: measurements on 481 men and women aged from 16 to 72 years. Br. J. Nutr. 32: 77-97, 1974.
9. Fox, E. L., and D. K. Mathews. Measurement of energy, work, and power. In: The Physiological Basis of Physical Education and Athletics. Philadelphia, PA: Saunders, 1981, p. 55-77.
10. Giesbrecht, G. G., and G. K. Bristow. A second postcooling afterdrop: more evidence for a convective mechanism. J. Appl. Physiol. 73: 1253-1258, 1992.
11. Giesbrecht, G. G., and G. K. Bristow. Influence of body composition on rewarming from immersion hypothermia. Aviat. Space Environ. Med. 66: 1144-1150, 1995.
12. Giesbrecht, G. G., and G. K. Bristow. Recent advances in hypothermia research. In: Thermoregulation: Tenth International Symposium on the Pharmacology of Thermoregulation, edited by C. M. Blatteis. New York: NY Acad Sci., 1997, p. 663-675.
13. Giesbrecht, G. G., G. K. Bristow, A. Uin, A. E. Ready, and R. A. Jones. Effectiveness of three field treatments for induced mild (33.0°C) hypothermia. J. Appl. Physiol. 63: 2375-2379, 1987.
14. Giesbrecht, G. G., M. B. Ducharme, and J. P. McGuire. Comparison of forced-air patient warming systems for perioperative use. Anesthesiology 80: 1-9, 1994.
15. Giesbrecht, G. G., M. Schroeder, and G. K. Bristow. Treatment of mild immersion hypothermia by forced-air warming. Aviat. Space Environ. Med. 65: 803-808, 1994.
16. Giesbrecht, G. G., D. I. Sessler, I. B. Mekjavic, M. Schroeder, and G. K. Bristow. Treatment of mild immersion hypothermia by direct body-to-body contact. J. Appl. Physiol. 76: 2373-2379, 1994.
17. Goheen, M. S. L., M. B. Ducharme, G. P. Kenny, C. E. Johnston, J. Frim, G. K. Bristow, and G. G. Giesbrecht. Efficacy of forced-air and inhalation rewarming by using a human model for severe hypothermia. J. Appl. Physiol. 83: 1635-1640, 1997.
18. Golden, G. S. C., and G. R. Hervey. The mechanism of the after-drop following immersion hypothermia in pigs. J. Physiol. (Lond.) 272: 26-27, 1977.
19. Hayward, J. S., J. D. Eckerson, and D. Kemna. Thermal and cardiovascular changes during three methods of resuscitation from mild hypothermia. Resuscitation 11: 21-33, 1984.
20. Jaffe, J. H., and W. R. Martin. Opioid analgesics and antagonists. In: Goodman and Gilman's The Pharmacological Basis of Therapeutics, edited by A. G. Gilman, T. W. Rall, A. S. Nies, and P. Taylor. New York: McGraw-Hill, 1990, p. 485-521.
21. Layton, R. P., W. H. J. Mints, J. F. Annis, M. J. Rack, and P. Webb. Calorimetry with heat flux transducers: comparison with a suit calorimeter. J. Appl. Physiol. 54: 1361-1367, 1983.
22. Macintyre, P. E., E. G. Pavlin, and J. F. Dwersteg. Effect of meperidine on oxygen consumption, carbon dioxide production, and respiratory gas exchange in postanesthesia shivering. Anesth. Analg. 66: 751-755, 1987.
23. Mekjavic, I. B., and O. Eiken. Inhalation rewarming from hypothermia: an evaluation in -20°C simulated field conditions. Aviat. Space Environ. Med. 66: 424-429, 1995.
24. 2O). J. Appl. Physiol. 73: 2246-2254, 1992.
25. Nicolaou, G., A. A. Chen, C. E. Johnston, G. P. Kenny, G. K. Bristow, and G. G. Giesbrecht. Clonidine decreases the vasoconstriction and shivering thresholds, without affecting the sweating threshold. Can. J. Anaesth. 44: 636-642, 1997.
26. Romet, T. T., and R. W. Hoskin. Temperature and metabolic responses to inhalation and bath rewarming protocols. Aviat. Space Environ. Med. 59: 630-634, 1988.
27. Webb, P. Afterdrop of body temperature during rewarming: an alternative explanation. J. Appl. Physiol. 60: 385-390, 1986.
28. White, J. D., A. B. Butterfield, K. A. Greer, S. Schoem, C. Johnson, and R. R. Holloway. Comparison of rewarming by radio wave regional hyperthermia and warm humidified inhalation. Aviat. Space Environ. Med. 55: 1103-1106, 1984.