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Schwab W, Bilgicyildirim, Funk RHW: Microphotography of the autonomic nerves in the rat knee: a fluorescence microscopic study. Anat Rec 1997, 247:109-118. This is the first study demonstrating nerve fibers in articular cartilage. Neurokinin A- and CGRP-immunoreactive fibers were found in the outer layer of articular cartilage of the rat knee joint. The findings may reflect a neurogenic pathway in the pathogenesis of rheumatoid arthritis.
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(1997)
Anat Rec
, vol.247
, pp. 109-118
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Schwab, W.1
Bilgicyildirim2
Funk, R.H.W.3
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103
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0031013118
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Calcitonin gene-related peptide enhances bone colony development in vitro
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Shin C, Bernard GW: Calcitonin gene-related peptide enhances bone colony development in vitro. Clin Orthop 1997, 334:335-344. This in vitro study demonstrates a stimulatory effect of CGRP on bone colony cells.
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(1997)
Clin Orthop
, vol.334
, pp. 335-344
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Shin, C.1
Bernard, G.W.2
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104
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0031032889
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Sensory and sympathetic innervation of the vertebral endplate in patients with degenerative disc disease
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Brown MF, Hukkanen MVJ, McCarthy ID, Redfern DRM, Batten JJ, Crock HV, Hughes SPF, Polak JM: Sensory and sympathetic innervation of the vertebral endplate in patients with degenerative disc disease. J Bone Joint Surg Br 1997, 79:147-153. An immunohistochemical study showing an increase in CGRP-positive nerve fibers in the endplate region of vertebral bodies in patients with degenerative disk disease. The authors speculate that the endplates and vertebral bodies are the probable sources of low back pain.
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(1997)
J Bone Joint Surg Br
, vol.79
, pp. 147-153
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Brown, M.F.1
Hukkanen, M.V.J.2
McCarthy, I.D.3
Redfern, D.R.M.4
Batten, J.J.5
Crock, H.V.6
Hughes, S.P.F.7
Polak, J.M.8
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