Actions of riluzole in animal models of CNS ischaemia and trauma

Reviews in Contemporary Pharmacotherapy

Volumn 8, Issue 4, 1997, Pages 227-235

  Obrenovitch, Tihomir P ^a,c   Urenjak, Jutta ^b  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

^c UNIVERSITY OF BRADFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

NEUROPROTECTIVE AGENT; RILUZOLE;

ANIMAL EXPERIMENT; ANIMAL MODEL; BRAIN INJURY; BRAIN ISCHEMIA; DISEASE SEVERITY; DOSE RESPONSE; ENERGY; INTRAPERITONEAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; NONHUMAN; REVIEW; SODIUM CURRENT; STROKE;

EID: 0030656213     PISSN: 09548602     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (20)

1. Araki H, Nojiri M, Kimura M, Aihara H. Effect of minaprine on 'delayed neuronal death' in Mongolian gerbils with occluded common carotid arteries. J Pharmacol Exp Ther 1987; 242: 686-691.
2. Artru AA, Michenfelder JD. Cerebral protective, metabolic, and vascular effects of phenytoin. Stroke 1980; 11: 377-382.
3. Barone FC, Feuerstein GZ, White RF. Brain cooling during transient focal ischaemia provides complex neuroprotection. Neurosci Biobehav Rev 1997; 21: 31-44.
4. Bramlett HM, Green EJ, Dietrich WD, Busto R, Globus MY-T, Ginsberg MD. Post-traumatic brain hypothermia provides protection from sensorimotor and cognitive-behavioral deficits. J Neurotrauma 1995; 12: 289-298.
5. Bullock R, Povlishock JT. The role of antiseizure prophylaxis following head injury. J Neurotrauma 1996; 13: 731-734.
6. Levine S, Payan H. Effect of ischemia and other procedures on the brain and retina of the gerbil (Meriones unguiculatus). Exp Neurol 1966; 16: 255-262.
7. Malgouris C, Bardot F, Daniel M et al. Riluzole, a novel antiglutamate, prevents memory loss and hippocampal neuronal damage in ischemic gerbils. J Neurosci 1989; 9: 3720-3727.
8. Mantz J, Chéramy A, Thierry A-M, Glowinski J, Desmonts J-M. Anesthetic properties of riluzole (54274 RP), a new inhibitor of glutamate neurotransmission. Anesthesiology 1992; 76: 844-848.
9. Massagli TL. Neurobehavioral effects of phenytoin, carbamazepine, and valproic acid. Implications for use in traumatic brain injury. Arch Phys Med Rehabil 199; 72: 219-226.
10. McIntosh TK. Novel pharmacologic therapies in the treatment of experimental traumatic brain injury: a review. J Neurotrauma 1993; 10: 215-261.
11. McIntosh TK, Vink R, Noble L et al. Traumatic brain injury in the rat: characterization of a lateral fluid-percussion model. Neuroscience 1989; 28: 233-234.
12. McIntosh TK, Smith DH, Voddi M, Perri BR, Stutzmann J-M. Riluzole, a novel neuroprotective agent, attenuates both neurologic motor and cognitive dysfunction following experimental brain injury in the rat. J Neurotrauma 1996; 13: 767-780.
13. Mizoule J, Meldrum B, Mazadier M et al. 2-Amino-6-trifluoromethoxy benzothiazole, a possible antagonist of excitatory amino acid neurotransmission. I. Anticonvulsant properties. Neuropharmacology 1985; 24: 767-773.
14. Nikolov R, Scheller D, Nikolova M. Study on the cerebral effects of sabeluzole. Methods Find Exp Clin Pharmacol 1991; 13: 385-390.
15. Nurse S, Corbett D. Neuroprotection after several days of mild, drug-induced hypothermia. J Cereb Blood Flow Metabol 1996; 16: 474-480.
16. Obrenovitch TP, Richards DA. Extracellular neurotransmitter changes in cerebral ischaemia. Cerebrovasc Brain Metab Rev 1995; 7: 1-54.
17. Onodera H, Sato G, Kogure K. Quantitative autoradiographic analysis of muscarinic cholinergic and adenosine A1 binding sites after transient forebrain ischemia in the gerbil. Brain Res 1987; 415: 309-322.
18. Pratt J, Ratuad J, Bardot F et al. Neuroprotective actions of riluzole in rodent models of global and focal cerebral ischaemia. Neurosci Lett 1992; 140: 225-230.
19. Pulsinelli WA, Brierley JB. A new model of bilateral hemispheric ischemia in the unanesthetized rat. Stroke 1979; 10: 267-272.
20. Rataud J, Debarnot F, Mary V, Pratt J, Stutzmann J-M. Comparative study of voltage-sensitive sodium channel blockers in focal ischaemia and electric convulsions in rodents. Neurosci Lett 1994; 172: 19-23.