Primary infection by HHV-6 variant B associated with a fatal case of hemophagocytic syndrome

New Microbiologica

Volumn 20, Issue 1, 1997, Pages 7-11

  Portolani, M ^a,b   Cermelli, C ^a   Meacci, M ^b   Pietrosemoli, P ^b   Pecorari, M ^b   Sabbatini, A M T ^b   Leoni, S ^b   Guerra, A ^b   Bonaccorsi, G ^b  

^a UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

^b UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

Author keywords

Hemophagocytic syndrome; HHV 6; PCR

Indexed keywords

IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; VIRUS ANTIBODY; VIRUS DNA;

ANIMAL; ARTICLE; CASE REPORT; CELL CULTURE; CERCOPITHECUS; CEREBROSPINAL FLUID; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FIBROBLAST; GENETICS; HERPES VIRUS; HISTIOCYTOSIS; HUMAN; HUMAN HERPESVIRUS 6; IMMUNOLOGY; INFANT; ISOLATION AND PURIFICATION; POLYMERASE CHAIN REACTION; VERO CELL;

ANIMALS; ANTIBODIES, VIRAL; CELLS, CULTURED; CERCOPITHECUS AETHIOPS; DNA, VIRAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FIBROBLASTS; HERPESVIRIDAE; HERPESVIRUS 6, HUMAN; HISTIOCYTOSIS, NON-LANGERHANS-CELL; HUMANS; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; INFANT; POLYMERASE CHAIN REACTION; VERO CELLS;

EID: 0030641155     PISSN: 11217138     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. ASANO, Y., and GROSE, C. Human herpesvirus type 6 infections. In: Glaser R., Jones J.F., Eds. Herpesvirus infections. New York: M. Dekker Inc., 1994, 227-244.
2. Di LUCA, D., DOLCETTI, P., MIRANDOLA, P., DE RE, V., SECCHIERO, P., CARBONE, A., BOIOCCHI, M., and CASSAI, E. (1994). Human herpesvirus 6: a survey of presence and variant distribution in normal peripheral lymphocytes and lymphoproliferative disorders. Journal of Infectious Diseases, 170, 211-215.
3. HUANG, L.M., LEE, C.Y., LIN, K.H., CHU, W.M., LEE, P.L., CHEN, R.I., CHEN, J.M., and LIN, D.T. (1990). Human herpesvirus 6 associated with fatal hemophagocytic syndrome. Lancet i, 60-61.
4. KONDO, K., KONDO, T., OKUNO, T., TAKAHASHI, M., and YAMANISHI, K. (1991). Latent human herpesvirus 6 infection of human monocytes/macrophages. Journal of General Virology, 72, 1401-1408.
5. KRUEGER, G.R.F. Pathology of Epstein-Barr virus (EBV)-associated disease (the lymphatic system). In: Levine, P.H., Ablashi, D.V., G.R. Pearson and Kottaridis S.D. eds. Epstein-Barr virus and associated diseases. Nijhoff. Boston. 1985, 106-130.
6. KRUEGER, G.R.F., KLUEPPELBERG, U., HOFFMANN, A., and ABLASHI, D.V. (1994). Clinical correlates of infection with human herpesvirus 6. In vivo, 8, 457-486.
7. Lusso, P., MARKHAM, P.D., TSCHACHLER, E., DI MARZO VERONESE, F., SALAHUDDIN, S.Z., AHLASHI, D.V., PAHWA, S., KROHN, K., and GALLO, R.C. (1988). In vitro cellular tropism of human B-lymphotropic virus (human herpesvirus-6). Journal of Experimental Medicine, 167, 1659-1670.
8. PORTOLANI, M., CERMELLI, C., PIETROSEMOLI, P., PECORARI, M., FARABEGOLI, F., CAVAZZUTI, G.R., BERTOLANI, M.F., and MICHELI, A. (1990). Isolation of HHV-6-related virus from children affected by infectious syndrome. Archives of Virology, 110, 143-149.
9. PORTOLANI, M., CERMELLI, C., MIRANDOLA. P., and DI LUCA, D. (1995). Isolation of human herpesvirus 7 from an infant with febrile syndrome. Journal of Medical Virology, 45, 282-283.
10. RISDALL, R.J., MCKENNA, R.W., and NESBIT, M.E. (1979). A benign histiocytic proliferation distinct from malignant histiocytosis. Cancer, 44, 993-1002.
11. ROZENBERG, F., and LEBON, P. (1991). Amplification and characterization of herpesvirus DNA in cerebrospinal fluid from patients with acute encephalitis. Journal of Clinical Microbiology, 29, 2412-2417.
12. SALAHUDDIN, S.Z., ABLASHI, D.V., MARKHAM, P.D., JOSEPHS, S.F., STURZNEGGER, S., KAPLAN, M., HALLIGAN, O., BIBERFELD, P., WONG-STAAL, F., KRAMARSKY, B., and GALLO, R.C. (1986). Isolation of a new virus, HBLV, in patients with lymphoproliferative disorders. Science, 234, 596-601.
13. SECCHIERO, P., CARRIGAN, D.R., ASANO, Y., BENEDETTI, L., CROWLEY, R.W., KOMAROFF, A.L., GALLO, R.C, and Lusso, P. (1995). Detection of human herpesvirus 6 in plasma of children with primary infection and immunosuppressed patients by polymerase chain reaction. Journal of Infectious Diseases, 171, 273280.
14. STEEPER, T.A., HORWITZ, C.A., ABLASHI, D.V., SALAHUDDIN, S.Z., SAXINGER, C., SALTZMAN, R., and SCHWARTZ, B. (1990). The spectrum of clinical and laboratory findings resulting from human herpesvirus-6 (HHV-6) in patients with mononucleosis-like illness not resulting from Epstein-Barr Virus or cytomegalovirus. American Journal of Clinical Pathology. 93, 776-783.
15. SU, I.J., HSIEH, H.J., and LEE, C.Y. (1989). Histiocytic medullary reticulosis: a lethal form of primary EBV infection in young children in Taiwan. Lancet, i, 389.
16. YAMANISHI, K., OKUNO, T., SHIRAKI, K., TAKAHASHI, M., ASANO, Y., and KURATA, T. (1988). Identification of human herpesvirus 6 as a causal agent for exanthem subitum. Lancet, i, 1065-1066.