Plasma nitric oxide in posttrauma critical illness: A function of "SEPSIS" and the physiologic state severity classification quantifying the probability of death

Shock

Volumn 7, Issue 1, 1997, Pages 17-28

  Rixen, Dieter ^b   Siegel, John H ^a   Espina, Noel ^a   Bertolini, Marie ^a  

^a RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF COLOGNE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CREATININE; NITRATE; NITRIC OXIDE;

ADULT; ADULT RESPIRATORY DISTRESS SYNDROME; ARTICLE; BLOOD; FEMALE; HOSPITALIZATION; HUMAN; MALE; MIDDLE AGED; MORTALITY; SEPSIS;

ADULT; CREATININE; FEMALE; HUMANS; MALE; MIDDLE AGED; NITRATES; NITRIC OXIDE; RESPIRATORY DISTRESS SYNDROME, ADULT; SEPSIS; SEVERITY OF ILLNESS INDEX;

EID: 0030640878     PISSN: 10732322     EISSN: None     Source Type: Journal    
DOI: 10.1097/00024382-199701000-00002     Document Type: Article

References (57)

1. Moncada S, Palmer RMJ, Higgs EA: Nitric oxide: physiology, pathophysiology and pharmacology. Pharmacol Reviews 43:109-142, 1991.
2. Fleming I, Furman BL, Gray GA, Guc MO, Julou-Schaeffer G, Bigaud M, Stoclet J-C, Parratt JR: Mechanisms of vascular impairment during endotoxaemia with special reference to the role of the L-arginine pathway. In Schlag G, Redl H, Siegel JH (eds): Second Wiggers-Bernard Conference on Shock, Sepsis and Organ Failure. Berlin, Heidelberg, New York: Springer, 1991, pp 399-424.
3. Leibovich SJ, Polverini PJ, Fong TW, Harlow LA, Koch AE: Production of angiogenic activity by human monocytes requires an L-arginine/nitric oxide-synthase-dependent effector mechanism. Proc Natl Acad Sci USA 91:4190-4194, 1994.
4. Knowles RG, Merrett M, Salter M, Moncada S: Differential induction of brain, lung and liver nitric oxide synthase by endotoxin in the rat. Biochem J 270:833-836, 1990.
5. Jorens PG, Vermeire PA, Herman AG: L-arginine-dependent nitric oxide synthase: A new metabolic pathway in the lung and airways. Eur Respir J 6:258-266,1993.
6. Szabo C: Alterations in nitric oxide production in various forms of circulatory shock. New Horizons 3:2-32, 1995.
7. Thiemermann C, Vane J: Inhibition of nitric oxide synthesis reduces the hypotension induced by bacterial lipopolysaccharides in rat in vivo. Eur J Pharmacol 182:591-595, 1990.
8. Thiemermann C, Szabo C, Mitchell JA, Vane JR: Vascular hyporeactivity to vasoconstrictor agents and haemodynamic decompensation in hemorrhagic shock is mediated by nitric oxide. Proc Natl Acad Sci USA 90: 267-271, 1993.
9. G-methyl-L-arginine restores arterial pressure in hemorrhaged rats. Circ Shock 40:47-52, 1993.
10. Lieberthal W, McGarry AE, Shells J, Valeri CR: Nitric oxide inhibition in rats improves blood pressure and renal function during hypovolemic shock. Am J Physiol 261:F868-F872, 1991.
11. Ochoa JB, Udekwu AO, Billiar TR, Curran RD, Cerra FB, Simmons RL, Peitzman AB: Nitrogen oxide levels in patients after trauma and during sepsis. Ann Surg 214:621-626, 1991.
12. Jacob TD, Ochoa JB, Udekwu AO, Wilkinson J, Murray T, Billiar TR, Simmons RL, Marion DW, Peitzman AB: Nitric oxide production is inhibited in trauma patients. J Trauma 35:590-597, 1993.
13. Rossaint R, Falke KJ, Lopez F, Slama K, Pison U, Zapol WM: Inhaled nitric oxide for the adult respiratory distress syndrome. N Engl J Med 328:399-405, 1993.
14. Weizberg E, Rudehill A, Lundberg JM: Nitric oxide inhalation attenuates pulmonary hypertension and improves gas exchange in endotoxin shock. Eur J Pharmacol 233:85-94, 1993.
15. Baker SP, O'Neill B, Haddon W, Long WB: The Injury Severity Score: A method for describing patients with multiple injuries and evaluating emergency care. J Trauma 14:187-196, 1974.
16. Teasdale G, Jennett B: Assessment of coma and impaired consciousness: A practical scale. Lancet 2:81-83, 1974.
17. Siegel JH, Rivkind AI, Dalal S, Goodzari S: Early physiologic predictors of injury severity and death in blunt multiple trauma. Arch Surg 125:498-508, 1990.
18. Bone RC, Members of the American College of Chest Physicians/ Society of Critical Care Medicine Consensus Conference Committee: American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference: Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Crit Care Med 20:864-874, 1992.
19. Laghi F, Siegel JH, Rivkind AI, et al: Respiratory index/pulmonary shunt relationship: Quantification of severity and prognosis in the post-traumatic adult respiratory distress syndrome. Crit Care Med 17:1121-1128, 1989.
20. Siegel JH, Farrell EF, Goldwyn RM, Friedman HP: The surgical implications of physiologic patterns in myocardial infarction shock. Surgery 72:126-141, 1972.
21. Siegel JH, Cerra FB, Coleman B, et al: Physiological and metabolic correlations in human sepsis. Surgery 86:163-193, 1979.
22. Siegel JH, Goodzari S, Coleman WP, et al: Quantifying the severity of the human response to injury and sepsis as a guide to the interpretation of pathophysiologic cytokine effects. In Schlag G, Redl H, Traber D (eds): Third Wiggers Bernard Conference on Shock, Sepsis and Organ failure. Berlin, New York: Springer-Verlag, 1993, pp 163-204.
23. Siegel JH, Rixen D, Friedman HP: Physiologic classification and stratifi-cation of illness severity of posttrauma "sepsis" patients as a basis for randomization of clinical trials. J Endotox Res 2:177-188, 1995.
24. Rixen D, Siegel JH, Friedman HP: "Sepsis/SIRS", physiologic classification, severity stratification, relation to cytokine elaboration and outcome prediction in posttrauma critical illness. J Trauma 41:1-17, 1996.
25. Bone RC, Fisher CJ, Clemmer TP, et al: Sepsis syndrome: A valid clinical entity. Crit Care Med 17:389-393, 1989.
26. Bernard GR, Artigas A, Brigham KL, et al: The American-European Consensus Conference on ARDS: definitions, mechanisms, relevant outcomes, and clinical trial coordination. Am J Respir Crit Care Med 149: 818-824, 1994.
27. 15N-labelled nitrate in humans: Effect of diet supplementation with ascorbic acid. Cancer Res 43:1921-1925, 1983.
28. 15N nitrate in biological fluids. Anal Biochem 126:131-158, 1982.
29. + when the Griess reaction is used to assay for nitrite. Anal Biochem 224:502-508, 1995.
30. Moshage H, Kok B, Huizenga JR, Jansen PLM: Nitrite and nitrate determinations in plasma: A critical evaluation. Clin Chem 41:892-896, 1995.
31. Siegel JH, Fichthorn J, Monteferrante J, Moody E, Box N, Nolan C, Ardrey R: Computer-based consultation in "care" of the critically ill patient. Surgery 80:350-364, 1976.
32. Siegel JH, Goodzari S, Guadelupi P, et al: The host defense to trauma and sepsis: Multiple organ failure as a manifestation of host defense failure disease. In Schlag G, Redl H (eds): Pathophysiology of shock, sepsis, and organ failure. Berlin, New York: Springer-Verlag, 1993, pp 626-664.
33. Evans T, Carpenter A, Kinderman H, Cohen J: Evidence of increased nitric oxide production in patients with the sepsis syndrome. Circ Shock 41:77-81, 1993.
34. Gomez-Jimenez J, Salgado A, Mourelle M, et al: L-Arginine: nitric oxide pathway in endotoxemia and human septic shock. Crit Care Med 23:253-258, 1995.
35. Green HD, Lewis RN, Nicherson ND, Heller AL: Blood flow, peripheral resistance and vascular tone, with observations on relationship between blood flow and cutaneous temperature. Am J Physiol 141:518-536, 1944.
36. Siegel JH, Greenspan M, DelGuercio LRM: Abnormal vascular tone, defective oxygen transport and myocardial failure in human septic shock. Ann Surg 165:504, 1967.
37. Rixen D, Siegel JH, Abu-Salih A, Bertolini M, Panagakos F, Espina N: Physiologic State Severity Classification as an indicator of posttrauma cytokine response. Shock 4:27-38, 1995.
38. Billiar TR, Curran RD, Stuehr DJ, West MA, Bentz BG, Simmons RL: An L-arginine dependent mechanism mediates Kupffer cell inhibition of hepatocyte protein synthesis in vitro. J Exp Med 169:1467-1472, 1989.
39. Neugebauer E, Holaday J: Handbook of mediators in septic shock. Boca Raton: CRC Press, 1993.
40. Wang P, Ba Z, Chaudry IH: Endothelial cell dysfunction occurs very early following trauma-hemorrhage and persists despite fluid resuscitation. Am J Physiol 265:H973-H979, 1993.
41. Symington PA, Ma XL, Lefer AM: Protective actions of S-nitroso-N-acetylpenicillamine (SNAP) in a rat model of hemonhagic shock. Meth Find Exp Clin Pharmacol 14:789-797, 1992.
42. Altura BM, Gebrewold A, Buron RW: Failure of microscopic metarterioles to elicit vasodilator responses to acetylcholine, bradykinin, histamine and substance P after ischemic shock, endotoxemia and trauma: possible role of endothelial cells. Microcirc Endothelium Lymphatics 2:121-127, 1985.
43. Ellison MD, Erb DE, Kontos HA, Povlishock JT: Recovery of impaired endothelium-dependent relaxation after fluid percussion injury in cats. Stroke 20:911-917, 1989.
44. Preiser J-C, Reper P, Vlasselaer D, Vray B, Zhang H, Metz G, Vanderkelen A, Vincent J-L: Nitric oxide production is increased in patients after burn injury. J Trauma 40:368-371, 1996.
45. Ochoa JB, Billiar TR, Peitzman AB: The role of nitric oxide in hemorrhagic shock and trauma. In Schlag G, Redl H (eds): Shock, sepsis, and organ failure-nitric oxide. New York: Springer Verlag, 1995, pp 84-101.
46. Rixen D, Siegel JH, Bertolini M, Espina N: Histamine and cytokine relationships in posttrauma critical illness. Shock 3(Suppl 2):29-30, 1995.
47. Thiemermann C, Wu C-C, Szabo C, Perretti M, Vane JR: Role of tumour necrosis factor in the induction of nitric oxide synthase in a rat model of endotoxin shock. Br J Pharmacol 110:177-182, 1993.
48. Szabo C, Wu C-C, Gross SS, Thiemermann C, Vane JR: Interleukin-1 contributes to the induction of nitric oxide synthase by endotoxin in vivo. Eur J Pharmacol 250:157-160, 1993.
49. Harbrecht BG, Di Silvio M, Demetris AJ, Simmons RL, Billiar TR: Tumor necrosis factor alpha regulates in vivo nitric oxide synthesis and induces liver injury during endotoxemia. Hepatology 20:1055-1060, 1994.
50. Cunha FQ, Assreuy J, Moss DW, Rees D, Leal LMC, Moncada S, Carrier M, O'Donnell CA, Liew FY: Differential induction of nitric oxide synthase in various organs of the mouse during endotoxaemia: Role of TNF-alpha and IL-1-beta. Immunology 81:211-215, 1994.
51. Geller DA, de Vera ME, Russell DA, Shapiro RA, Nussler AK, Simmons RL, Billiar TR: A central role for IL-1β in the in vitro and in vivo regulation of hepatic inducible nitric oxide synthase: IL-1β induces hepatic nitric oxide synthesis. J Immunol 155:4890-4898, 1995.
52. Lamparter B, Gross SS, Levi R: Nitric oxide and the cardiovascular actions of histamine. Agents Actions, Special Conference Issue. C187-C190, 1992.
53. Sganga G, Siegel JH, Brown G, Coleman B, Wiles CE III, Beizberg H, Wedel S, Placko R: Reprioritization of hepatic plasma protein release in trauma and sepsis. Arch Surg 120:187-199, 1985.
54. Stadler J, Bentz BG, Harbrecht BG, et al: Tumor necrosis factor alpha inhibits hepatocyte mitochondrial respiration. Ann Surg 216:539-554, 1991.
55. Geng Y, Hansson GK, Holme E: Interferon-gamma and tumor necrosis factor synergize to induce nitric oxide production and inhibit mitochondrial respiration in vascular smooth muscle cells. Circ Res 71:1268-1276, 1992.
56. Sherman MP, Loro ML, Wong VZ, Tashkin DP: Cytokine-and Pneumocystis carinii induced L-arginine oxidation by murine and human pulmonary alveolar macrophages. J Protozool 38:2349-2369, 1991.
57. Gaboury J, Woodman RC, Granger DN, Reinhardt P, Kubes P: Nitric oxide prevents leukocyte adherence: role of superoxide. Am J Physiol 265:H862-H867, 1993.