Human succinic semialdeyde dehydrogenase: Molecular cloning and chromosomal localization

Advances in Experimental Medicine and Biology

Volumn 414, Issue , 1997, Pages 253-260

  Trettel, Flavia ^a   Malaspina, Patrizia ^a   Jodice, Carla ^a   Novelletto, Andrea ^a   Slaughter, Clive A ^b   Caudle, Deborah L ^c   Hinson, Debra D ^c   Chambliss, Ken L ^c   Gibson, K Michael ^c,d,e  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^c BAYLOR UNIVERSITY MEDICAL CENTER   (United States)

^d UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^e BAYLOR RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID; SUCCINATE SEMIALDEHYDE DEHYDROGENASE; ALDEHYDE DEHYDROGENASE; ALDH5A1 PROTEIN, HUMAN; ALDH5A1 PROTEIN, RAT; RECOMBINANT PROTEIN;

AMINO ACID SEQUENCE; BRAIN TISSUE; CHROMOSOMAL LOCALIZATION; CONFERENCE PAPER; DNA SEQUENCE; HYBRIDIZATION; MOLECULAR CLONING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SOUTHERN BLOTTING; ANIMAL; ARTICLE; BIOSYNTHESIS; BRAIN; CHEMISTRY; CHROMOSOME 6; CHROMOSOME MAP; ENZYMOLOGY; GENETICS; HAMSTER; HUMAN; HYBRID CELL; LIVER; MOLECULAR GENETICS; OPEN READING FRAME; POLYMERASE CHAIN REACTION; RAT; YEAST ARTIFICIAL CHROMOSOME;

ALDEHYDE OXIDOREDUCTASES; AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BRAIN; CHROMOSOME MAPPING; CHROMOSOMES, ARTIFICIAL, YEAST; CHROMOSOMES, HUMAN, PAIR 6; CLONING, MOLECULAR; CRICETINAE; HUMANS; HYBRID CELLS; LIVER; MOLECULAR SEQUENCE DATA; OPEN READING FRAMES; POLYMERASE CHAIN REACTION; RATS; RECOMBINANT PROTEINS; SUCCINATE-SEMIALDEHYDE DEHYDROGENASE;

EID: 0030640401     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: None     Document Type: Conference Paper

References (15)

1. Chambliss, K.L. and Gibson, K.M.: Succinic semialdhyde dehydrogenase from mammalian brain: subunit analysis using polyclonal antiserum. Int.J.Biochem. 24 (1992) 1493-1499.
2. +-dependent succinic semialdehyde dehydrogenase from rat and human: cDNA isolation, evolutionary homology, and tissue expression. J.Biol.Chem. 270 (1995) 461-467.
3. Chambliss, K.L., Zhang, Y.-A., Rossier, E., Vollmer, B. and Gibson, K.M.: Enzymatic and immunologic identification of succinic semialdehyde dehydrogenase in rat and human neural and nonneural tissues. J.Neurochem. 65 (1995) 851-855.
4. Gibson, K.M., Christensen, E., Jakobs, C., Fowler, B., Clarke, M.A., Wallace, G., Hammersen, G., Raab, K., Kobori, J., Moosa, A., Vollmer, B., Rossier, E., Iafolla, A.K., Matern, D., Brouwer, O.F., Hofman, K., Aksu, F., Weber, H.-P., Bakkeren, J.A.J.M., Gabreels, F., Bluestone, D., Barron, T.F., Beauvais, P., Rabier, D., Santos, C., Umansky, R. and Lehnen, W.: The clinical phenotype of succinic semialdehyde dehydrogenase deficiency (4-hydroxybutyric aciduria): case reports of 23 new patients, in press.
5. Hempel J, Nicholas H. and Lindahl, R.: Aldehyde dehydrogenases: widespread structural and functional diversity within a shared framework. Protein Sci. 2 (1993) 1890-1900.
6. 1-pyrroline-5-carboxylate dehydrogenase. J.Biol.Chem. 271 (1996) 9795-9800.
7. Jakobs, C., Jaeken, J. and Gibson, K.M.: Inherited disorders of GABA metabolism. J.Inher.Metab.Dis. 16 (1993) 704-715.
8. Kurys, G., Shah, P.C., Kikonygo, A., Reed, D., Ambroziak, W., Pietruszko, R.: Human aldehyde dehydrogenase: cDNA cloning and primary structure of the enzyme that catalyzes dehydrogenation of 4-aminobutyraldehyde. Eur.J.Biochem. 218 (1993) 311-320.
9. Malaspina, P., Roetto, A., Trettel, F., Jodice, C., Blasi, P., Frontali, M., Carella, M., Franco, B., Camaschella, C. and Novelletto, A.: Construction of YAC contig covering human chromosome 6p22, in press.
10. +-dependent succinic semialdehyde dehydrogenase. Arch.Biochem.Biophys. 266 (1988) 386-396.
11. Scriver, C.R. and Gibson, K.M.: Disorders of β- and γ- amino acids in free and peptide-linked forms. In Scriver, C.R., Beaudet, A.L., Sly, W.S. and Valle, D. (Eds.), The Metabolic and Molecular Basis of Inherited Disease. 7th ed. McGraw-Hill, N.Y., 1995, pp. 1349-1368.
12. Snead, O.C.: Antiabsence seizure activity of specific GABA (B) and gamma-hydroxybutyric acid receptor antagonists. Pharmacol.Biochem.Behav. 53 (1996) 73-79.
13. Tillakaratne, N.J.K., Medina-Kauwe, L. and Gibson, K.M.: Gamma-amniobutyric acid (GABA) metabolism in mammalian neural and nonneural tissues. Comp.Biochem.Physiol. 112A (1995) 247-263.
14. 1-pyrroline-5-carboxylic acid dehydrogenase activity. Science 185 (1974) 1053-1054.
15. Wahle E., Keller W.: The biochemistry of 3′-end cleavage and polyadenylation of messenger RNA precursors. Annu.Rev.Biochem. 61 (1992) 419-440.