How do stem cells decide what to do?

CIBA Foundation Symposia

Volumn , Issue 204, 1997, Pages 3-18

  Cross, Michael A ^a   Heyworth, Clare M ^a   Dexter, T Michael ^a  

^a CHRISTIE HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH PROMOTOR; TRANSCRIPTION FACTOR;

ANIMAL; BONE MARROW CELL; CELL DIFFERENTIATION; CYTOLOGY; GENE EXPRESSION REGULATION; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; HUMAN; PHYSIOLOGY; REVIEW;

ANIMALS; BONE MARROW CELLS; CELL DIFFERENTIATION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GROWTH SUBSTANCES; HEMATOPOIESIS; HEMATOPOIETIC STEM CELLS; HUMANS; TRANSCRIPTION FACTORS;

EID: 0030637755     PISSN: 03005208     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (34)

1. Brady G, Billia F, Knox J et al 1995 Analysis of gene expression in a complex differentiation hierarchy by global amplification of cDNA from single cells. Curr Biol 5:909-922
2. Cross MA, Heyworth CM, Murrell AM, Bockamp EO, Dexter TM, Green AR 1994 Expression of lineage restricted transcription factors precedes lineage specific differentiation in a multipotent haemopoietic progenitor cell line. Oncogene 9:3013-3016
3. Dexter TM, Coutinho LH, Spooncer E et al 1990 Stromal cells in haemopoiesis. In: Molecular control of haemopoiesis. Wiley, Chichester (Ciba Found Symp 148) p 76-95
4. Ding DX, Rivas CI, Heaney ML, Raines MA, Vera JC, Golde DW 1994 The alpha subunit of the human granulocyte-macrophage colony-stimulating factor receptor signals for glucose transport via a phosphorylation-independent pathway. Proc Natl Acad Sci USA 91:2537-2541
5. Evan GI, Wyllie AH, Gilbert CS et al 1992 Induction of apoptosis in fibroblasts by c-myc protein. Cell 69:119-128
6. Fairbairn LJ, Cowling GJ, Reipert BM, Dexter TM 1993 Suppression of apoptosis allows differentiation and development of a multipotent hemopoietic cell line in the absence of added growth factors. Cell 74:823-832
7. 3 delta-chain gene enhancers are DNase I-hypersensitive in hemopoietic progenitor cells. Proc Natl Acad Sci USA 89:3424-3428
8. Heberlein C, Fischer KD, Stoffel M et al 1992 The gene for erythropoietin receptor is expressed in multipotential hematopoietic and embryonal stem cells: evidence for differentiation stage-specific regulation. Mol Cell Biol 12:1815-1826
9. Heyworth CM, Dexter TM, Kan O, Whetton AD 1990 The role of hemopoietic growth factors in self-renewal and differentiation of IL-3-dependent multipotential stem cells. Growth Factors 2:197-211
10. Heyworth CM, Whetton AD, Nicholls S, Zsebo K, Dexter TM 1992 Stem cell factor directly stimulates the development of enriched granulocyte-macrophage colony-forming cells and promotes the effects of other colony-stimulating factors. Blood 80:2230-2236
11. Heyworth CM, Dexter TM, Nicholls SE, Whetton AD 1993 Protein kinase C activators can interact synergistically with granulocyte colony-stimulating factor or interleukin-6 to stimulate colony formation from enriched granulocyte-macrophage colony-forming cells. Blood 81:894-900
12. Heyworth CM, Alauldin M, Cross MA, Fairbairn LJ, Dexter TM, Whetton AD 1995 Erythroid development of the FDCP-Mix A4 multipotent cell line is governed by the relative concentrations of erythropoietin and interleukin 3. Br J Haematol 91:15-22
13. Jiang J, Levine M 1993 Binding affinities and cooperative interactions with bHLH activators delimit threshold responses to the dorsal gradient morphogen. Cell 72:741-752
14. Keller JR, Ortiz M, Ruscetti FW 1995 Steel factor (c-kit ligand) promotes the survival of hematopoietic stem/progenitor cells in the absence of cell division. Blood 86:1757-1764
15. Kodama H, Nose M, Niida S, Nishikawa S, Nishikawa S 1994 Involvement of the c-kit receptor in the adhesion of hematopoietic stem cells to stromal cells. Exp Hematol 22:979-984
16. Lin EY, Orlofsky A, Wang H, Reed JC, Prystowsky MB 1996 A1, a Bcl-2 family member, prolongs cell survival and permits myeloid differentiation. Blood 87:983-992
17. Metcalf D 1980 Clonal analysis of proliferation and differentiation of paired daughter cells: action of granulocyte-macrophage colony-stimulating factor on granulocyte-macrophage precursors. Proc Natl Acad Sci USA 77:5327-5330
18. Metcalf D 1993 Hematopoietic regulators: redundancy or subtlety? Blood 82:3515-3523
19. Mollers B, Klages S, Wedel A et al 1992 The mouse M-lysozyme gene domain: identification of myeloid and differentiation specific DNase I-hypersensitive sites and of a 3′-cis acting regulatory element. Nucleic Acids Res 20:1917-1924
20. Nguyen HQ, Hoffman-Liebermann B, Liebermann DA 1993 The zinc finger transcription factor Egr-1 is essential for and restricts differentiation along the macrophage lineage. Cell 72:197-209
21. Nicholls SE, Heyworth CM, Dexter TM, Lord JM, Johnson GD, Whetton AD 1995 IL-4 promotes macrophage development by rapidly stimulating lineage restriction of bipotent granulocyte-macrophage colony-forming cells. J Immunol 155:845-853
22. Robb L, Lyons I, Li R et al 1995 Absence of yolk sac hematopoiesis from mice with a targeted disruption of the Scl gene. Proc Natl Acad Sci USA 92:7075-7079
23. Rodel JE, Link DC 1996 Suppression of apoptosis during cytokine deprivation of 32D cells is not sufficient to induce complete granulocytic differentiation. Blood 87:858-864
24. Scott EW, Simon MC, Anastasi J, Singh H 1994 Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages. Science 265:1573-1577
25. Spooncer E, Heyworth CM, Dunn A, Dexter TM 1986 Self-renewal and differentiation of interleukin-3-dependent multipotent stem cells are modulated by stromal cells and serum factors. Differentiation 31:111-118
26. Testa U, Pelosi E, Gabbianelli M et al 1993 Cascade transactivation of growth factor receptors in early human hematopoiesis. Blood 81:1442-1456
27. Tsai FY, Keller G, Kuo FC et al 1994 An early haematopoietic defect in mice lacking the transcription factor GATA-2. Nature 371:221-226
28. von Wangenheim HR, Schofield R, Kyffin S, Klein B 1977 Studies on erythroid-committed precursor cells in the polycythaemic mouse. Biomedicine 27:337-340
29. Walker F, Nicola NA, Metcalf D, Burgess AW 1985 Hierarchical down-modulation of hemopoietic growth factor receptors. Cell 43:269-276
30. Wentraub H 1993 The myoD family and myogenesis, networks and thresholds. Cell 75:1241-1244
31. Whetton AD, Heyworth CM, Nicholls SE et al 1994 Cytokine-mediated protein kinase C activation is a signal for lineage determination in bipotential granulocyte macrophage colony-forming cells. J Cell Biol 125:651-659
32. Williams GT, Smith CA, Spooncer E, Dexter TM, Taylor DR 1990 Haemopoietic colony stimulating factors promote cell survival by suppressing apoptosis. Nature 343:76-79
33. Wong A, Sakamoto KM 1995 Granulocyte-macrophage colony-stimulating factor induces the transcriptional activation of egr-1 through a protein kinase A-independent signaling pathway. J Biol Chem 270:30271-30273
34. Wu H, Lui X, Jaenisch R, Lodish HF 1995 Generation of committed erythroid BFU-e and CFU-e does not require erythropoietin or the erythropoietin receptor. Cell 83:59-67