P53 overexpression in squamous cell carcinoma of the esophagus

Annals of Surgical Oncology

Volumn 4, Issue 1, 1997, Pages 37-45

  Baron, Paul L ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

P53 esophageal cancer; Risk factors; Tumor suppressor gene

Indexed keywords

MONOCLONAL ANTIBODY; PROTEIN P53;

ARTICLE; BIOSYNTHESIS; CASE CONTROL STUDY; ESOPHAGUS TUMOR; FEMALE; GENETICS; HUMAN; IMMUNOHISTOCHEMISTRY; MALE; MUTATION; NEGRO; PATHOLOGY; PHYSIOLOGY; RISK FACTOR; SQUAMOUS CELL CARCINOMA; TUMOR SUPPRESSOR GENE; UNITED STATES;

AFRICAN CONTINENTAL ANCESTRY GROUP; ANTIBODIES, MONOCLONAL; CARCINOMA, SQUAMOUS CELL; CASE-CONTROL STUDIES; ESOPHAGEAL NEOPLASMS; FEMALE; GENES, P53; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MUTATION; RISK FACTORS; SOUTH CAROLINA; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0030636966     PISSN: 10689265     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02316809     Document Type: Article

References (5)

1. Brown LM, Blot WJ, Schuman SH, Smith VM, Ershow AG, Marks RD, Fraumeni JF. Environmental factors and high risk of esophageal cancer among men in coastal South Carolina. J Natl Cancer Inst 1988;80:1620-5.
2. Hollstein MC, Peri L, Mandard AM, et al. Genetic analysis of human esophageal tumors from two high incidence geographic areas: frequent p53 base substitutions and absence of ras mutations. Cancer Res 1991;51:4102-6.
3. Audrezet MP, Robaszkiewicz M, Mercier B, et al. TP53 gene mutation profile in esophageal squamous cell carcinomas. Cancer Res 1993;53:5745-9.
4. Gates CE, Reed CE, Bromberg JS, Everett ET, Baron PL. p53 mutations found with high incidence in patients with squamous cell carcinoma of the esophagus. J Thorac Cardiovasc Surg 1994;108:148-52.
5. Harris CC, Hollstein M. Clinical implications of the p55 tumor-suppressor gene. N Engl J Med 1993;329:1318-26.