Triggering of Motile Behavior in T Lymphocytes via Cross-Linking of α4β1 and αLβ2

Journal of Immunology

Volumn 158, Issue 1, 1997, Pages 76-84

  Hauzenberger, Dan ^a,b   Klominek, Julius ^b   Holgersson, Jan ^b   Bergström, Sten Erik ^b   Sundqvist, Karl Gösta ^a,b  

^a UMEÅ UNIVERSITY HOSPITAL   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CD3 ANTIGEN; HOMING RECEPTOR; INTEGRIN; LIGAND; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; MONOCLONAL ANTIBODY; VERY LATE ACTIVATION ANTIGEN; VERY LATE ACTIVATION ANTIGEN 4;

ADULT; ARTICLE; BIOSYNTHESIS; CELL ADHESION; CELL CLONE; CELL LINE; CELL MOTION; HUMAN; IMMUNOLOGY; METABOLISM; PROTEIN BINDING; T LYMPHOCYTE;

ADULT; ANTIBODIES, MONOCLONAL; ANTIGENS, CD3; CELL ADHESION; CELL LINE; CELL MOVEMENT; CLONE CELLS; HUMANS; INTEGRIN ALPHA4BETA1; INTEGRINS; LIGANDS; LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN-1; PROTEIN BINDING; RECEPTORS, LYMPHOCYTE HOMING; RECEPTORS, VERY LATE ANTIGEN; T-LYMPHOCYTES;

EID: 0030636791     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (39)

1. Picker, L. J. 1994. Control of lymphocyte homing. Curr. Opin. Immunol. 6:394.
2. Picker, L. J., and E. C. Butcher. 1992. Physiological and molecular mechanisms of lymphocyte homing. Annu. Rev. Immunol. 10:561.
3. Butcher, E. C. 1990. Warner-Lambert/Parke-Davis Award lecture: cellular and molecular mechanisms that direct leukocyte traffic. Am. J. Pathol. 136:3.
4. Lawrence, M. B., and T. A. Springer. 1991. Leukocytes roll on a selectin at physiologic flow rates: distinction from and prerequisite for adhesion through integrins. Cell 65:859.
5. Butcher, E. C. 1991. Leukocyte-endothelial cell recognition: three (or more) steps to specificity and diversity. Cell 67:1033.
6. Springer, T. A. 1994. Traffic signals for lymphocyte recirculation and leucocyte emigration: the multistep paradigm. Cell 76:301.
7. Springer, T. A. 1990. Adhesion receptors of the immune system. Nature 346:425.
8. Lasky, L. A., M. S. Singer, D. Dowbenko, Y. Imai, W. J. Henzel, C. Grimley, C. Fennie, N. Gillett, S. R. Watson, and S. D. Rosen. 1992. An endothelial ligand for L-selectin is a novel mucin-like molecule. Cell 69:927.
9. Baumhueter, S., M. S. Singer, W. Henzel, S. Hemmerich, M. Renz, S. D. Rosen, and L. A. Lasky. 1993. Binding of L-selectin to the vascular sialomucin CD34. Science 262:436.
10. Berg, E. L., L. M. McEvoy, C. Berlin, R. F. Bargatze, and E. C. Butcher. 1993. L-selectin-mediated lymphocyte rolling on MadCAM-1. Nature 366:695.
11. Oppenheimer-Marks, N., L. S. Davis, and P. E. Lipsky. 1990. Human T lymphocyte adhesion to endothelial cells and transendothelial migration: alteration of receptor use relates to the activation status of both the T cell and endothelial cell. J. Immunol. 145:140.
12. + T cells that exhibit a transendothelial migratory capacity. J. Immunol. 154:3062.
13. Oppenheimer-Marks, N., and M. Ziff. 1988. Migration of lymphocytes through endothelial cell monolayers: augmentation by interferon-gamma. Cell. Immunol. 114:307.
14. Kavanaugh, A. F., E. Lightfool, P. E. Lipsky, and N. Oppenheimer-Marks. 1991. Role of CD11/CD18 in adhesion and transendothelial migration of T cells: analysis utilizing CD18-deficient T cell clones. J. Immunol. 146:4149.
15. Miller, M. D., and M. S. Krangel. 1992. Biology and biochemistry of the chemokines: a family of chemotactic and inflammatory cytokines. CRC Crit. Rev. Immunol. 12:17.
16. Campanero, M. R., R. Pulido, M. A. Ursa, M. Rodriguez-Moya, M. O. de Landazuri, and F. Sanchez-Madrid. 1990. Regulation of the VLA integrin-ligand interactions through the β1 subunit. J. Cell Biol. 110:2157.
17. + lymphocytes. Nature 339:152.
18. Juliano, R. L., and S. Haskill. 1993. Signal transduction from the extracellular matrix. J. Cell Biol. 120:577.
19. Kornberg, L. J., H. S. Earp, C. E. Turner, C. Prockop, and R. L. Juliano. 1991. Signal transduction by integrins: increased protein tyrosine phosphorylation caused by clustering of the beta 1 integrins. Proc. Natl. Acad. Sci. USA 88:3892.
20. Dustin, M. L., and T. A. Springer. 1989. T-cell receptor cross-linking transiently stimulates adhesiveness through LFA-1. Nature 341:619.
21. Shimizu, Y., G. A. Van Seventer, K. J. Horgan, and S. Shaw. 1990. Regulated expression and binding of three VLA β1: integrin receptors on T-cells. Nature 345:250.
22. Hauzenberger, D., J. Klominek, and K. G. Sundqvist. 1994. Functional specialization of fibronectin-binding β1-integrins in T lymphocyte migration. J. Immunol. 153:960.
23. Engvall, E., and E. Ruoslahti. 1977. Binding of soluble form of fibroblast surface protein, fibronectin, to collagen. Int. J. Cancer 20:1.
24. Aruffo, A., I. Stamenkovic, M. Melnick, C. B. Underhill, and B. Seed. 1990. CD44 is the principal cell surface receptor for hyaluronate. Cell 61:1303.
25. Van Reijsen, F. C., C. A. F. M. Bruijnzeel-Koomen, F. S. Kalthoff, E. Maggi, S. Romagnani, J. K. T. Westland, and G. C. Mudde. 1992. Skin-derived aeroallergen-specific T-cell clones of Th2 phenotype in patients with atopic dermatitis. J. Allergy Clin. Immunol. 90:184.
26. Klominek, J., K.-H. Robért, and K.-G. Sundqvist. 1993. Chemotaxis and haptotaxis of human malignant mesothelioma cells: effects of fibronectin, laminin, type IV collagen and an autocrine motility factor-like substance. Cancer Res. 53:4376.
27. Schwartz, M. A. 1993. Signaling by integrins: implications for tumorigenesis. Cancer Res. 53:1503.
28. Ruoslahti, E., and J. C. Reed. 1994. Anchorage dependence, integrins and apoptosis. Cell 77:477.
29. Gilman, A. G. 1987. G proteins: transducers of receptor-generated signals. Annu. Rev. Biochem. 56:615.
30. de Sousa, M. 1981. Lymphocyte Circulation: Experimental and Clinical Aspects. John Wiley and Sons, Chichester.
31. Bargatze, R. F., and E. C. Butcher. 1993. Rapid G protein-regulated activation event involved in lymphocyte binding to high endothelial venules. J. Exp. Med. 178:367.
32. DeFranco, A. L. 1993. Signalling pathways activated by protein tyrosine phosphorylation in lymphocytes. Curr. Opin. Cell Biol. 6:364.
33. Kobayashi, E., H. Nakano, M. Morimoto, and T. Tamaoki. 1989. Calphostin C UCN-1028C., a novel microbial compound, is a highly potent and specific inhibitor of protein kinase C. Biochem. Biophys. Res. Commun. 159:548.
34. Castagna, M., Y. Takai, K. Kaibuchi, K. Sano, U. Kikkawa, and Y. Nishizuka. 1982. Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters. J. Biol. Chem. 257:7847.
35. Wedgwood, J. F., L. Hatam, and V. R. Bonagura. 1988. Effect of interferon-gamma and tumor necrosis factor on the expression of class I and class II major histocompatibility molecules by cultured human umbilical vein endothelial cells. Cell. Immunol. 111:1.
36. Ruszczak, Z., M. Detmar, E. Imcke, and C. E. Orfanos. 1990. Effects of rIFN alpha, beta, and gamma on the morphology, proliferation, and cell surface antigen expression of human dermal microvascular endothelial cells in vitro. J. Invest. Dermatol. 95:693.
37. May, M. J., G. Entwistle, M. J. Humphries, and A. Ager. 1993. VCAM-1 is a CS1 peptide-inhibitable adhesion molecule expressed by lymph node high endothelium. J. Cell Sci. 106:109.
38. Dustin, M. L., R. Rothlein, A. K. Bhan, C. A. Dinarello, and T. A. Springer. 1986. Induction by IL-1 and interferon-γ: tissue distribution, biochemistry, and function of a natural adherence molecule ICAM-1. J. Immunol. 137:245.
39. Romanic, A. M., and J. A. Madri. 1994. The induction of 72-kD gelatinase in T cells upon adhesion to endothelial cells is VCAM-1 dependent. J. Cell Biol. 125:1165.