Effect of Somatotropin and Insulin-Like Growth Factor-1 on Milk Lipid and Protein Synthesis in Vitro

Journal of Dairy Science

Volumn 80, Issue 1, 1997, Pages 37-45

  Keys, J E ^a   Van Zyl, J P ^b   Farrell Jr , H M ^c  

^a AGRICULTURAL RESEARCH SERVICE   (United States)

^b AGRICULTURAL RESEARCH COUNCIL   (South Africa)

^c AGRICULTURAL RESEARCH SERVICE   (United States)

Author keywords

Bovine somatotropin; Deoxyribonucleic acid; Insulin like growth factor I; Milk protein

Indexed keywords

BOVINAE;

DNA; FATTY ACID; GROWTH HORMONE; LIPID; MILK PROTEIN; RNA; SOMATOMEDIN C;

ADIPOSE TISSUE; ANIMAL; ARTICLE; BIOSYNTHESIS; CATTLE; CHEMISTRY; COCULTURE; CULTURE TECHNIQUE; DRUG EFFECT; FEMALE; FLOW CYTOMETRY; LIVER; METABOLISM; MILK; UDDER;

ADIPOSE TISSUE; ANIMALS; CATTLE; COCULTURE TECHNIQUES; CULTURE TECHNIQUES; DNA; FATTY ACIDS, NONESTERIFIED; FEMALE; FLOW CYTOMETRY; GROWTH HORMONE; INSULIN-LIKE GROWTH FACTOR I; LIPIDS; LIVER; MAMMARY GLANDS, ANIMAL; MILK; MILK PROTEINS; RNA;

EID: 0030636386     PISSN: 00220302     EISSN: None     Source Type: Journal    
DOI: 10.3168/jds.S0022-0302(97)75910-1     Document Type: Article

References (24)

1. Banerjee, M. R., J. E. Wagner, and D. L. Kinder. 1971. DNA synthesis in the absence of cell reproduction during functional differentiation of mouse mammary gland. Life Sci. 10:867.
2. Bauman, D. E., and R. G. Vernon. 1993. Effects of exogenous bovine somatotropin on lactation. Annu. Rev. Nutr. 13:437.
3. Baumrucker, C. R., and B. H. Stemberger. 1989. Insulin and insulin-like growth factor-I stimulate DNA synthesis in bovine mammary tissue in vitro. J. Anim. Sci. 67:3503.
4. Disenhaus, C., L. Belair, and J. Djiane. 1988. Characterisation et evolution physiologique des recepteurs pour les insulin-like growth factors I et II (IGFs) dans la glande mammaire de brebis. Reprod. Nutr. Dev. 28:241.
5. Eppard, P. J., D. E. Bauman, J. Bitman, D. L. Wood, R. M. Akers, and W. A. House. 1985. Effect of dose of bovine growth hormone on milk composition: α-lactalbumin, fatty acids, and mineral elements. J. Dairy. Sci. 68:3047.
6. 14C] acetate into lipids by co-cultures of bovine mammary, liver, and adipose tissue explants. Domest. Anim. Endocrinol. 6:87.
7. Flint, D. J., E. Tonner, J. Beattie, and M. Gardner. 1994. Several insulin-like growth factor I analogues and complexes of insulin-like growth factors-I and -II with insulin-like growth factor-binding protein-3 fail to mimic the effect of growth hormone upon lactation in the rat. J. Endocrinol. 140:211.
8. Gertler, A., N. Cohen, and A. Maoz. 1983. Human growth hormone but not ovine or bovine growth hormone exhibits galactopoietic prolactin-like activity in organ culture from bovine lactating mammary gland. Mol. Cell. Endocrinol. 33:169.
9. Goodman, G. T., R. M. Akers, K. H. Friderici, and H. A. Tucker. 1983. Hormonal regulation of α-lactalbumin secretion from bovine mammary tissue cultured in vitro. Endocrinology 112: 1324.
10. Kerr, D. E., B. Laarveld, R. K. Chaplin, and J. G. Manns. 1991. Effects of a somatotropin challenge on serum IGF-I concentrations and short-term milk production response in dairy cows. Can. J. Anim. Sci. 71:683.
11. Kerr, D. E., B. Laarveld, M. I. Fehr, and J. G. Manns. 1991. Profiles of serum IGF-I concentrations in calves from birth to eighteen months of age and in cows throughout the lactation cycle. Can. J. Anim. Sci. 71:695.
12. Keys, J. E., A. V. Capuco, and D. L. Wood. 1991. Lipid synthesis by co-cultures of mammary, liver, and adipose tissue explants from sometribove (recombinant methionyl bovine somatotropin)-treated dairy cows. In Vitro Cell. Dev. Biol. 27A:249.
13. Keys, J. E., and J. Djiane. 1988. Somatotrophic and lactogenic binding sites in mammary and liver tissue of lactating cows. J. Recept. Res. 8:731.
14. 14C]thymidine uptake versus flow cytometry cell cycle analysis. In Vitro Cell. Dev. Biol. 30A:50.
15. Peel, C. J., L. D. Sandles, K. J. Quelch, and A. C. Herington. 1985. The effects of long-term administration of bovine growth hormone on the lactational performance of identical-twin dairy cows. Anim. Prod. 41:135.
16. Pell, J. M., and P. C. Bates. 1992. Differential actions of growth hormone and insulin-like growth factor-I on tissue protein metabolism in dwarf mice. Endocrinology 130:1942.
17. Peri, I., A. Shamay, M. F. McGrath, R. J. Collier, and A. Gertler. 1992. Comparative mitogenic and galactopoietic effects of IGF-I, IGF-II and DES-3-IGF-I in bovine mammary gland in vitro. Cell Biol. Int. Rep. 16:359.
18. Prosser, C. G., C. Royle, I. R. Fleet, and T. B. Mepham. 1991. The galactopoietic effect of bovine growth hormone in goats is associated with increased concentrations of insulin-like growth factor-I in milk and mammary tissue. J. Endocrinol. 128:457.
19. ® Guide for Personal Computers, Version 6 Edition. 1987. SAS Inst. Inc., Cary, NC.
20. Schams, D., F. Graf, B. Graule, M. Abele, and S. Prokopp. 1991. Hormonal changes during lactation in cows of three different breeds. Livest. Prod. Sci. 27:285.
21. Smith, G. H., and B. K. Vonderhaar. 1981. Functional differentiation in mouse mammary gland epithelium is attained through DNA synthesis, inconsequent of mitosis. Dev. Biol. 88: 167.
22. Sod-Moriah, U. A., and G. H. Schmidt. 1968. Deoxyribonucleic acid content and proliferative activity of rabbit mammary gland epithelial cells. Exp. Cell Res. 49:584.
23. Trippel, S. B., M. T. Corvol, M. F. Dumontier, R. Rapparort, H. H. Hung, and H. J. Mankin. 1989. Effect of somatomedin-C/ insulin-like growth factor I and growth hormone on cultured growth plate and articular chondrocytes. Pediatr. Res. 25:76.
24. Tucker, H. A., and R. A. Merkel, 1987. Applications of hormones in the metabolic regulation of growth and lactation in ruminants. Fed. Proc. 46:300.