Preparation of artificial ceroid/lipofuscin by UV-oxidation of subcellular organelles

Mechanisms of Ageing and Development

Volumn 99, Issue 1, 1998, Pages 61-78

  Nilsson, Evalill ^a   Yin, Dazhong ^a  

^a LINKÖPING UNIVERSITY   (Sweden)

Author keywords

Aging; Lipofuscin; Lysosomes; Oxygen radicals

Indexed keywords

CALCIUM; CEROID; CHLOROFORM; DODECYL SULFATE SODIUM; IRON; LIPOFUSCIN; METHANOL; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

ANIMAL TISSUE; ARTICLE; AUTOFLUORESCENCE; CELL GROWTH; CELL ORGANELLE; CONTROLLED STUDY; ENDOCYTOSIS; FIBROBLAST; GLYCATION; HUMAN; HUMAN CELL; LIVER CELL NUCLEUS; LIVER LYSOSOME; LIVER MICROSOME; LIVER MITOCHONDRION; MALE; MICROFLUOROMETRY; MICROSCOPY; NONHUMAN; OXIDATION; PHENOTYPE; PRIORITY JOURNAL; RAT; TECHNIQUE; THIN LAYER CHROMATOGRAPHY; TRANSMISSION ELECTRON MICROSCOPY; ULTRAVIOLET IRRADIATION; X RAY DIFFRACTION;

ANIMALS; CELLS, CULTURED; CEROID; FIBROBLASTS; FREE RADICALS; GLYCOSYLATION; LIPOFUSCIN; MALE; ORGANELLES; OXIDATION-REDUCTION; RATS; RATS, SPRAGUE-DAWLEY; ULTRAVIOLET RAYS;

ANIMALIA;

EID: 0030631569     PISSN: 00476374     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0047-6374(97)00091-2     Document Type: Article

References (45)

1. Abok K., Fredriksson B., Brunk U. An experimental model system for leishmaniasis. An ultrastructural study on cultured macrophages exposed to Leishmania parasites and sodium stibogluconate. APMIS. 96:1988;589-595.
2. Baynes, J.W., Monnier, V.M., 1989. The Maillard Reaction in Aging, Diabetes, and Nutrition. Alan R. Liss, New York.
3. Brizzee K.R., Cancilla P.A., Sherwood N., Timiris P.S. The amount and distribution of pigments in neurons and glia of the cerebral cortex. J. Gerontol. 24:1969;127-135.
4. Brunk U., Ericsson J.L.E. Electron microscopical studies on rat brain neurons. Localization of acid phosphatase and mode of formation of lipid bodies. J. Ultrastruct Res. 38:1972;1-15.
5. Brunk U.T., Jones C.B., Sohal R.J. A novel hypothesis of lipofuscinogenesis and cellular aging based on interactions between oxidative stress and autophagocytosis. Mutat. Res. 275:1992;395-403.
6. Buege J.A., Aust S.D. Microsomal lipid peroxidation. Methods Enzymol. 52:1977;302-310.
7. Chio K.S., Reiss U., Fletcher B., Tappel A.L. Peroxidation of subcellular organelles: formation of lipofuscinlike fluorescent pigments. Science. 166:1969;1535-1536.
8. Costanzo L.L., Guidi G.D., Giuffrida S., Sortino S., Condorelli G. Antioxidant effect of inorganic ions on UVC and UVB induced lipid peroxidation. J. Inorg. Bioch. 59:1995;1-13.
9. Cutler, R.G., 1995. Longevity determinant genes, dysdifferentiation and oxidative stress. In: Cutler, R.G., Packer, L., Bertram, J., Mori, A. (Eds.), Oxidative Stress and Aging. Birkhäuser Verlag Basel, Switzerland, pp. 15-19.
10. Davies K.J.A. A secondary antioxidant defense role for proteolytic systems. Basic Life Sci. 49:1988;575-585.
11. deDuve C., deBarsy T., Poole B., Trouet A., Tulkens P., van Hoof F. Lysosomotropic agents. Biochem. Pharmacol. 23:1974;2495-2631.
12. Eldred G.E., Katz M.L. Fluorophores of the human retinal pigment epithelium: separation and spectral characterization. Exp. Eye Res. 47:1988;71-86.
13. Eldred G.E., Katz M.L. The autofluorescent products of lipid peroxidation may not be lipofuscin-like. Free Radic. Biol. Med. 7:1989;157-163.
14. Eldred G.E., Lasky M.R. Retinal age pigments generated by self-assembling lysosomotropic detergents. Nature. 361:1993;724-726.
15. Eldred, G.E., 1987. Questioning the nature of the fluorophores in age pigments. In: Totaro, E.A., Glees, P., Pisanti, F.A. (Eds.), Advances in Age Pigments Research. Pergamon, Oxford, pp. 23-36.
16. Eldred G.E. Lipofuscin fluorophore inhibits lysosomal protein degradation and may cause early stages of macular degeneration. Gerontology. 41(Suppl. 2):1995;15-28.
17. Elleder, M., 1981. Chemical characterization of age pigment. In: Sohal, R.S. (Ed.), Age Pigments. Elsvier, Amsterdam, pp. 204-241.
18. Esterbauer H., Schaur R.J., Zollner H. Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes. Free Radic. Biol. Med. 11:1991;81-128.
19. Gao G., Johansson U., Rundquist I, Öllinger K Lipofuscin-induced autofluorescence of living neonatal rat cardiomyocytes in culture. Mech. Ageing Dev. 73:1994;79-86.
20. Girotti A.W. Photodynamic lipid peroxidation in biological systems. Photochem. Photobiol. 51:1990;497-509.
21. Glees, P., Hasan, M., 1976. Lipofuscin. In: Neuronal Aging and Diseases, Chapter 6. Georg Thieme, Stuttgart, pp. 30-33.
22. Gutteridge J.M.C., Heys A.D., Lunec J. Fluorescent malondialdehyde polymers from hydrolysed 1,1,3,3-tetramethoxypropane. Anal. Chim. Acta. 94:1977;209-211.
23. Janero D.R. Malondialdehyde and thiobarbituric acid-reactivity as diagnostic indices of lipid peroxidation and peroxidative tissue injury. Free Radic. Biol. Med. 9:1990;515-540.
24. Jazwinski S.M. Longevity, genes, and aging. Science. 273:1996;54-59.
25. Jolly R.D., Douglas B.V., Davey P.M., Roiri J.E. Lipofuscin in bovine muscle and brain: a model for studying age pigment. Gerontology. 41(Supplement 2):1995;283-293.
26. Kikugawa, K., 1990. Involvement of lipid oxidation products in the formation of fluorescent and cross-linked membrane proteins. In: Vigo-pelfrey, C. (Ed.), Membrane Lipid Oxidation, vol. 2. CRC Press, Boca Raton, FL, pp. 171-189.
27. Labuza, T.P., Reineccius, G.A., Monnier, V., O'Brien, J., Baynes, J.W. (Eds.), 1994. Maillard Reaction in Chemistry, Food, and Health. The Royal Society of Chemistry.
28. Matsumoto Y., Watanabe T., Suga T., Fujitani H. Inhibitory effects of quaternary ammonium compounds on lysosomal degradation of endogenous proteins. Chem. Pharm. Bull. 37:1989;516-518.
29. Porta, E.A., Hartroft, W.S., 1969. Lipid pigments in relation to aging and dietary factors. In: Wolman, M. (Ed.), Pigments in Pathology. Academic press, New York, pp. 191-235.
30. Reichel W., Hollander J., Clark J.H., Strehler B.L. Lipofuscin pigment accumulation as a function of age and distribution in rodent brain. J. Gerontol. 23:1968;71-78.
31. Reichel W. Lipofuscin pigment accumulation and distribution in five rat organs as a function of age. J. Gerontol. 23:1968;145-153.
32. Rubin, E., Farber, J.L. (Eds.), 1994. Pathology, Chap. 1, 2nd ed. J.B. Lippincott, pp. 1-31.
33. Seglen P.O. Inhibitions of lysosomal function. Methods Enzymol. 96:1983;937-964.
34. Siakotos, A.N., Armstrong, D., 1975. Age pigment, a biochemical indicator of intracellular aging. In: Ordy, J.M., Brizzee, K.R. (Eds.), Neurobiology of Aging. Plenum, New York, pp. 369-399.
35. Sohal, R.S., 1987. Quantification of lipofuscin: a critique of the current methodology. In: Totaro, E.A., Glees, P., Pisanti, F.A. (Eds.), Advances in Age Pigments Research. Pergamon, Oxford, pp. 85-91.
36. Sohal R.S. Oxidative stress, caloric restriction, and aging. Science. 273:1996;59-63.
37. Strehler B.L., Mark D.D., Mildvan A.S., Gee M.V. Rate of magnitude of age pigment accumulation in the human myocardium. J. Gerontol. 14:1959;430-439.
38. Strehler, B.L., 1964. On the histochemistry and ultrastructure of age pigment. In: Strehler, B.L. (Ed.), Advances in Gerontological Research, vol. 1. Academic Press, New York, pp. 343-384.
39. Tappel, A.L., 1975. Lipid peroxidation and fluorescent molecular damage to membranes. In: Trump, B.F., Arstila, A.U. (Eds.), Pathobiology of Cell Membranes, vol. 1. Academic Press, New York, pp. 145-170.
40. Wihlmark U., Wrigstad A., Roberg K., Brunk U.T., Nilsson S.E.G. Formation of lipofuscin in cultured retinal pigment epithelial cell exposed to pre-oxidized photoreceptor outer segments. APMIS. 104:1996;272-279.
41. Yin D., Brunk U.T. Oxidized ascorbic acid and reaction products between ascorbic and amino acids might constitute part of age pigments. Mech. Ageing Dev. 61:1991;99-112.
42. Yin, D., Brunk, U.T., 1995. Carbonyl toxification hypothesis of biological aging. In: Macieira-Coelho, A. (Ed), Molecular Basis of Aging. CRC Press, London, pp. 421-436.
43. Yin, D., Brunk, U.T., 1997. Autofluorescent ceroid/lipofuscin. In: Armstrong, D. (Ed.), Methods of Molecular Biology. Humana Press, (in press).
44. Yin D. Aging, age pigments, and concentration-dependent shift of autofluorescence. Age. 17:1994;53-58.
45. Yin D. Biochemical basis of lipofuscin, ceroid, and age pigment-like fluorophores. Free Radic. Biol. Med. 21:1996;871-888.