Quantification of proopiomelanocortin mRNA in peripheral lymphocytes of alcoholics

Alcohol

Volumn 15, Issue 1, 1998, Pages 43-50

  Winkler, A ^a   Schmidt, L G ^b   Rommelspacher, H ^b   Melzig, M F ^a  

^a LEIBNIZ INSTITUT FÜR MOLEKULARE PHARMAKOLOGIE   (Germany)

^b FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

Alcoholism; Gene expression; Lymphocytes; POMC; Endorphin

Indexed keywords

MESSENGER RNA;

ADULT; ALCOHOL CONSUMPTION; ALCOHOLISM; ARTICLE; CELL LEVEL; CLINICAL ARTICLE; CONTROLLED STUDY; DETOXIFICATION; DIAGNOSTIC VALUE; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; HYPOPHYSIS CELL; LYMPHOCYTE; MALE;

EID: 0030627452     PISSN: 07418329     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0741-8329(97)00096-7     Document Type: Article

References (31)

1. 1. Angeli, A.; Masera, R. G.; Staurenghi, A. H.; Solomon, S.; Bateman, A.; Sartori, M. L.; Lazzero, A.; Griot, G.: The expanding field of hypothalamic-pituitary-adrenal modulation of human natural killer cell activity. Ann. NY Acad. Sci. 719:328-342; 1994.
2. 2. Bateman, A.; Singh, A.; Kral, T.; Solomon, S.: The immune-hypothalamic-pituitary-adrenal axis. Endocr. Rev. 10:92-100; 1989.
3. 3. Blalock, J. E.; Smith, E. M.: Human leucocyte Interferon: Structural and biological retatedness to adrenocorticotropic hormone and endorphins. Proc. Natl. Acad. Sci. USA 77:5972-5974; 1980.
4. 4. Blalock, J. E.: Production of peptide hormones and neurotransmitters by the immune system. In: Blalock, J. E., ed. Neuroimmunoendocrinology, vol. 52. 1992:1-24.
5. 5. Buzzetti, R.; Giovannini, C.; Mcloughlin, L.; Rees, L. H.: Proopiomelanocortin gene expression in cells of the immune system. In: Negri, M.; Lotti, G.; Grossman, A., eds. Clinical perspectives in endogenous opioid peptides. 1992:15-28.
6. 6. del Arbol, J. L.; Aguirre, J. C.; Raya, J.; Rico, J.; Ruiz-Requena, M. E.; Miranda, T.: Plasma concentrations of fl-endorphin, adrenocorticotropic hormone, and cortisol in drinking and abstinent chronic alcoholics. Alcohol 12:525-529; 1995.
7. 7. Froehlich, J. C.; Harts, J.; Lumeng, L.; Li, T.-K.: Naloxone attenuates voluntary ethanol intake in rats selectively bred for high ethanol preference. Pharmacol. Biochem. Behav. 35:385-390; 1990.
8. 8. Gianoulakis, C.; Barcomb, A.: Effect of acute ethanol in vivo and in vitro on the β-endorphin system in the rat. Life Sci. 40:19-28; 1987.
9. 9. Gianoulakis, C.; de Waele, J.-P.: Genetics of alcoholism: Role of the endogenous opioid system. Metab. Brain Dis. 9:105-131; 1994.
10. 10. Gianoulakis, C.; De Waele, J.-P.; Thavundayil, J.: Implication of the endogenous opioid system in excessive ethanol consumption. Alcohol 13:19-23; 1996.
11. 11. Gordis, E.; Tabakoff, B.; Goldman, D.; Berg, K.: Finding gene(s) for alcoholism. JAMA 263:2094-2095; 1990.
12. 12. Harbour-McMenamin, D.; Smith, E. M.; Blalock, J. E.: Bacterial lipopolysaccharide induction of leucocyte derived ACTH and endorphins. Infect. Immun. 48:813-817; 1985.
13. 13. Heijnen, C. J.; Kavelaars, A.; Ballieux, R. E.: β-Endorphin: Cytokine and neuropeptide. Immunol. Rev. 119:41-63; 1991.
14. 14. Hyytiä, P.; Sinclair, J. D.: Responding for oral ethanol after naloxone treatment by alcohol-preferring AA rats. Alcohol. Clin. Exp. Res. 17:631-636; 1993.
15. 15. Ikonen, E.; Manninen, T.; Peltonen, L.; Syvänen, A.-C.: Quantitative determination of rare mRNA species by PCR and solid-phase minisequencing. PCR Methods Appl. 1:234-240; 1992.
16. 16. Kavelaars, A.; Berkenbosch, F.; Croiset, G.; Ballieux, R. E.; Heijnen, C. J.: Induction of β-endorphin secretion by lymphocytes after SC administration of corticotropin-releasing factor. Endocrinology 126:759-764; 1990.
17. 17. Lavender, P.; Johnson, M.; Rees, L.; Clark, A.: Expression of the short proopiomelanocortin message in transfected rat somatotrophs. J. Endocrinol. 123:51; 1989.
18. 18. Law, V.; Payne, L. C.; Weigent, D. A.: Effects of streptozotocin-induced diabetes on lymphocyte POMC and growth hormone gene expression in the rat. J. Neuroimmunol. 49:35-44; 1994.
19. 19. Maier, C. C.; Blalock, J. E.: PCR-based cloning, sequencing, and exon mapping of lymphocyte-derived neuroendocrine peptides. Immunomethods 5:3-7; 1994.
20. 20. Meadows, G. G.; Wallendal, M.; Kosugi, A.; Wunderlich, J.; Singer, D. S.: Ethanol induces marked changes in lymphocyte populations and natural killer cell activity in mice. Alcohol. Clin. Exp. Res. 16:474-479; 1992.
21. 21. Payne, L. C.; Weigent, D. A.; Blalock, J. E.: Induction of pituitary sensitivity to interleukin-1: A new function for corticotropin-releasing hormone. Biochem. Biophys. Res. Commun. 198:480-484;1994.
22. 22. Przewlocki, R.; Hassan, A. H. S.; Lason, W.; Epplen, C.; Herz, A.; Stein, C.: Gene expression and localization of opioid peptides in immune cells of inflamed tissue: Functional role in antinociception. Neuroscience 48:491-500; 1992.
23. 23. Schäfer, M.; Carter, L.; Stein, C.: Interleukin 1β and corticotropin-releasing factor inhibit pain by releasing opioids from immune cells in inflamed tissue. Proc. Natl. Acad. Sci. USA 91:4219-4223; 1994.
24. 24. Smith, E. M.; Shawn Galin, F.; LeBoeuf, R. D.; Coppenhaver, D. H.; Harbour, D. V.; Blalock, J. E.: Nucleotide and amino acid sequence of lymphocyte-derived corticotropin: Endotoxin induction of a truncated peptide. Proc. Natl. Acad. Sci. USA 87:1057-1060; 1990.
25. 25. Syvänen, A.-C.: Detection of point mutations in human genes by the solid-phase minisequencing method. Clin. Chim. Acta 226: 225-236; 1994.
26. 26. Takahashi, H.; Hakamata, Y.; Watanabe, Y.; Kikuno, R.; Miyata, T.; Numa, S.; Complete nucleotide sequence of the human corticotropin-beta-lipotropin precursor gene. Nucleic Acid. Res. 11:6847-6858; 1983.
27. 27. Topel, H.: Beta-endorphin genetics in the etiology of alcoholism. Alcohol 5:159-165; 1988.
28. 28. van Woudenberg, A. D.; Metzelaar, M. J.; van der Kleij, A. A. M.; de Wied, D.; Burbach, J. P. H.; Wiegant, V. M.: Analysis of proopiomelanocortin (POMC) messenger ribonucleic acid and POMC-derived peptides in humanperipheral blood mononuclear cells: No evidence for a lymphocyte-derived POMC system. Endocrinology 133:1922-1933; 1993.
29. 29. Wajs, E.; Gupta, D.: Pineal gland participates in the regulation of POMC gene expression in the immune system of the rat. Neuroendocrinol. Lett. 17:63-70; 1995.
30. 30. Weigent, D. A.; Blalock, J. E.: Growth hormone and the immune system. Prog. Neuroendocrinimmunol. 3:231-241; 1990.
31. 31. Winkler, A.; Roske, I.; Furkert, J.; Fickel, J.; Melzig, M. F.: Effects of various kinds of chronic ethanol treatment on the POMC gene expression in the rat pituitary and the plasma β-endorphin content. Alcohol Alcohol. 30:231-238; 1995.