메뉴 건너뛰기




Volumn 43, Issue C, 1997, Pages 205-229

Experimental Models for Evaluating Enzyme Induction Potential of New Drug Candidates in Animals and Humans and a Strategy for Their Use

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450;

EID: 0030627337     PISSN: 10543589     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S1054-3589(08)60207-0     Document Type: Article
Times cited : (1)

References (177)
  • 1
    • 0001413057 scopus 로고
    • Evidence for the function of D-glucaric acid as an indicator for drug induced enhanced metabolism through the glucuronic acid pathway in man
    • Aarts E.M. Evidence for the function of D-glucaric acid as an indicator for drug induced enhanced metabolism through the glucuronic acid pathway in man. Biochem. Pharmacol. 14 (1964) 359-363
    • (1964) Biochem. Pharmacol. , vol.14 , pp. 359-363
    • Aarts, E.M.1
  • 2
    • 0015238212 scopus 로고
    • D-glucaric-acid excretion as a test for hepatic enzyme induction
    • Aarts E.M. D-glucaric-acid excretion as a test for hepatic enzyme induction. Lancet 1 704 (1971) 859
    • (1971) Lancet , vol.1 , Issue.704 , pp. 859
    • Aarts, E.M.1
  • 3
    • 0014168787 scopus 로고
    • Enzymatic synthesis of steroid sulphates. III. Isolation and properties of estrogen sulphotransferase of bovine adrenal glands
    • Adams J.B., and Poulos A. Enzymatic synthesis of steroid sulphates. III. Isolation and properties of estrogen sulphotransferase of bovine adrenal glands. Biochim. Biophys. Acta 146 (1967) 493-508
    • (1967) Biochim. Biophys. Acta , vol.146 , pp. 493-508
    • Adams, J.B.1    Poulos, A.2
  • 4
    • 0028047394 scopus 로고
    • Abnormal bone mineral metabolism after long-term anticonvulsant treatment
    • Alderman C.P., and Hill C.L. Abnormal bone mineral metabolism after long-term anticonvulsant treatment. Ann. Pharmacother. 28 (1994) 47-48
    • (1994) Ann. Pharmacother. , vol.28 , pp. 47-48
    • Alderman, C.P.1    Hill, C.L.2
  • 5
    • 0024584510 scopus 로고
    • Purification of two isozymes of rat liver microsomal cytochrome P450 with testosterone 7;ga-hydroxylase activity
    • Arlotto M.P., Greenway D.J., and Parkinson A. Purification of two isozymes of rat liver microsomal cytochrome P450 with testosterone 7;ga-hydroxylase activity. Arch. Biochem. Biophys. 270 (1989) 441-457
    • (1989) Arch. Biochem. Biophys. , vol.270 , pp. 441-457
    • Arlotto, M.P.1    Greenway, D.J.2    Parkinson, A.3
  • 6
    • 0027523486 scopus 로고
    • Use of single sample clearance estimates of cytochrome P450 substrates to characterize human hepatic CYP status in vivo
    • Bachmann K.A., and Jauregui L. Use of single sample clearance estimates of cytochrome P450 substrates to characterize human hepatic CYP status in vivo. Xenobiotica 23 3 (1993) 307-315
    • (1993) Xenobiotica , vol.23 , Issue.3 , pp. 307-315
    • Bachmann, K.A.1    Jauregui, L.2
  • 7
    • 0030068752 scopus 로고    scopus 로고
    • Rifampin drastically reduces plasma concentrations and effects of oral midazolam
    • Backman J.T., Olkkola K.T., and Neuvonen P.J. Rifampin drastically reduces plasma concentrations and effects of oral midazolam. Clin. Pharmacol. Ther. 59 (1996) 7-13
    • (1996) Clin. Pharmacol. Ther. , vol.59 , pp. 7-13
    • Backman, J.T.1    Olkkola, K.T.2    Neuvonen, P.J.3
  • 8
    • 0020856024 scopus 로고
    • Clinical utility of breath tests for the assessment of hepatic function
    • Baker A.L., Kotake A.N., and Schoeller D.A. Clinical utility of breath tests for the assessment of hepatic function. Semin. Liver Dis. 3 4 (1983) 318-329
    • (1983) Semin. Liver Dis. , vol.3 , Issue.4 , pp. 318-329
    • Baker, A.L.1    Kotake, A.N.2    Schoeller, D.A.3
  • 10
    • 0026680310 scopus 로고
    • Divergent effects of different enzyme-inducing agents on endogenous and exogenous testosterone
    • Bammel A., van der Mee K., Ohnhaus E.E., and Kirch W. Divergent effects of different enzyme-inducing agents on endogenous and exogenous testosterone. Eur. J. Clin. Pharmacol. 42 (1992) 641-644
    • (1992) Eur. J. Clin. Pharmacol. , vol.42 , pp. 641-644
    • Bammel, A.1    van der Mee, K.2    Ohnhaus, E.E.3    Kirch, W.4
  • 11
    • 0025035723 scopus 로고
    • Enzyme induction and inhibition
    • Barry M., and Freely J. Enzyme induction and inhibition. Pharmacol. Ther. 48 (1990) 71-94
    • (1990) Pharmacol. Ther. , vol.48 , pp. 71-94
    • Barry, M.1    Freely, J.2
  • 12
    • 0028095346 scopus 로고
    • Reduction of thyroid hormone levels and alteration of thyroid function by four representative UDP-glucuronosyltransferase inducers in rats
    • Barter R.A., and Klaassen C.D. Reduction of thyroid hormone levels and alteration of thyroid function by four representative UDP-glucuronosyltransferase inducers in rats. Toxicol. Appl. Pharmacol. 128 (1994) 9-17
    • (1994) Toxicol. Appl. Pharmacol. , vol.128 , pp. 9-17
    • Barter, R.A.1    Klaassen, C.D.2
  • 14
    • 0028567499 scopus 로고
    • Induction and autoinduction properties of rifamycin derivatives: A review of animal and human studies
    • Benedetti M.S., and Dostert P. Induction and autoinduction properties of rifamycin derivatives: A review of animal and human studies. Environ. Health Perspect. 102 9 (1994) 101-105
    • (1994) Environ. Health Perspect. , vol.102 , Issue.9 , pp. 101-105
    • Benedetti, M.S.1    Dostert, P.2
  • 16
    • 0029077901 scopus 로고
    • Brain mitochondrial cytochromes P450: Xenobiotic metabolism, presence of multiple forms and their selective inducibility
    • Bhagwat S.V., Boyd M.R., and Ravindranath V. Brain mitochondrial cytochromes P450: Xenobiotic metabolism, presence of multiple forms and their selective inducibility. Arch. Biochem. Biophys. 320 1 (1995) 73-83
    • (1995) Arch. Biochem. Biophys. , vol.320 , Issue.1 , pp. 73-83
    • Bhagwat, S.V.1    Boyd, M.R.2    Ravindranath, V.3
  • 17
    • 0025992813 scopus 로고
    • A simple non-invasive procedure for the investigation of cytochrome P-450 IIIA dependent enzymes in humans
    • Bienvenu T., Rey E., Pons G., D'Athis P., and Olive G. A simple non-invasive procedure for the investigation of cytochrome P-450 IIIA dependent enzymes in humans. Int. J. Clin. Pharmacol. Ther. Toxicol. 29 (1991) 441-445
    • (1991) Int. J. Clin. Pharmacol. Ther. Toxicol. , vol.29 , pp. 441-445
    • Bienvenu, T.1    Rey, E.2    Pons, G.3    D'Athis, P.4    Olive, G.5
  • 18
    • 0015926539 scopus 로고
    • Effects of phenobarbital and 3-methylcholanthrene on substrate specificity of rat liver microsomal UDP-glucuronyltransferase
    • Bock K.W., Frohling W., Remmer H., and Rexer B. Effects of phenobarbital and 3-methylcholanthrene on substrate specificity of rat liver microsomal UDP-glucuronyltransferase. Biochim. Biophys. Acta 327 (1973) 46-56
    • (1973) Biochim. Biophys. Acta , vol.327 , pp. 46-56
    • Bock, K.W.1    Frohling, W.2    Remmer, H.3    Rexer, B.4
  • 19
    • 0018145527 scopus 로고
    • Determination of microsomal UDP-glucuronyl-transferase in needle-biopsy specimens of human liver
    • Bock K.W., Brunner G., Hoensch H., Huber E., and Josting D. Determination of microsomal UDP-glucuronyl-transferase in needle-biopsy specimens of human liver. Eur. J. Clin. Pharmacol. 14 (1978) 367-373
    • (1978) Eur. J. Clin. Pharmacol. , vol.14 , pp. 367-373
    • Bock, K.W.1    Brunner, G.2    Hoensch, H.3    Huber, E.4    Josting, D.5
  • 20
    • 0025602894 scopus 로고
    • Induction of drug-metabolizing enzymes by xenobiotics
    • Bock K.W., Lipp H.P., and Bock-Hennig B.S. Induction of drug-metabolizing enzymes by xenobiotics. Xenobiotica 20 (1990) 1101-1111
    • (1990) Xenobiotica , vol.20 , pp. 1101-1111
    • Bock, K.W.1    Lipp, H.P.2    Bock-Hennig, B.S.3
  • 21
    • 0028985925 scopus 로고
    • The kinetics of the auto-induction of ifosfamide metabolism during continuous infusion
    • Boddy A.V., Cole M., Pearson A.D.J., and Idle J.R. The kinetics of the auto-induction of ifosfamide metabolism during continuous infusion. Cancer Chemother. Pharmacol. 36 (1995) 53-60
    • (1995) Cancer Chemother. Pharmacol. , vol.36 , pp. 53-60
    • Boddy, A.V.1    Cole, M.2    Pearson, A.D.J.3    Idle, J.R.4
  • 22
    • 0027074986 scopus 로고
    • Anti-liver microsomes autoantibodies and dihydralazine-induced hepatitis: Specificity of autoantibodies and inductive capacity of the drug
    • Bourdi M., Gautier J.C., Mircheva J., Larrey D., Guillouzo A., Andre C., Belloc C., and Beaune P.H. Anti-liver microsomes autoantibodies and dihydralazine-induced hepatitis: Specificity of autoantibodies and inductive capacity of the drug. Mol. Pharmacol. 42 (1992) 280-285
    • (1992) Mol. Pharmacol. , vol.42 , pp. 280-285
    • Bourdi, M.1    Gautier, J.C.2    Mircheva, J.3    Larrey, D.4    Guillouzo, A.5    Andre, C.6    Belloc, C.7    Beaune, P.H.8
  • 23
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72 (1976) 248-254
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 24
    • 0023215959 scopus 로고
    • Enzyme induction in humans-clinical aspects-an overview
    • Breckenridge A. Enzyme induction in humans-clinical aspects-an overview. Pharmacol. Ther. 33 (1987) 95-99
    • (1987) Pharmacol. Ther. , vol.33 , pp. 95-99
    • Breckenridge, A.1
  • 25
    • 0021276491 scopus 로고
    • Induction of cytochrome P450 by xenobiotics
    • Bresnick E., Foldes R., and Hines R.N. Induction of cytochrome P450 by xenobiotics. Pharmacol. Rev. 36 2 (1984) 43S-51S
    • (1984) Pharmacol. Rev. , vol.36 , Issue.2
    • Bresnick, E.1    Foldes, R.2    Hines, R.N.3
  • 26
    • 0028095629 scopus 로고
    • Assessment of liver metabolic function-clinical implications
    • Brockmöller J., and Roots I. Assessment of liver metabolic function-clinical implications. Clin. Pharmacokinet. 27 3 (1994) 216-248
    • (1994) Clin. Pharmacokinet. , vol.27 , Issue.3 , pp. 216-248
    • Brockmöller, J.1    Roots, I.2
  • 27
    • 0028558737 scopus 로고
    • Induction of cytochrome P4501A by smoking or omeprazole in comparison with UDP-glucuronosyltransferase in biopsies of human duodenal mucosa
    • Buchthal J., Grund K.E., Buchmann A., Schrenk D., Beaune P., and Bock K.W. Induction of cytochrome P4501A by smoking or omeprazole in comparison with UDP-glucuronosyltransferase in biopsies of human duodenal mucosa. Eur. J. Clin. Pharmacol. 47 (1995) 431-435
    • (1995) Eur. J. Clin. Pharmacol. , vol.47 , pp. 431-435
    • Buchthal, J.1    Grund, K.E.2    Buchmann, A.3    Schrenk, D.4    Beaune, P.5    Bock, K.W.6
  • 29
    • 0016333916 scopus 로고
    • Ethoxyresorufin: Direct fluorometric assay of a microsomal O-dealkylation which is preferentially inducible by 3-methylcholanthrene
    • Burke M.D., and Mayer R.T. Ethoxyresorufin: Direct fluorometric assay of a microsomal O-dealkylation which is preferentially inducible by 3-methylcholanthrene. Drug Metab. Dispos. 2 (1974) 583-588
    • (1974) Drug Metab. Dispos. , vol.2 , pp. 583-588
    • Burke, M.D.1    Mayer, R.T.2
  • 30
    • 0028106482 scopus 로고
    • Cytochrome P450 specificities of alkoxyresorufin o-dealkylation in human and rat liver
    • Burke M.D., Thompson S., Weaver R.J., Wolf C.R., and Mayer R.T. Cytochrome P450 specificities of alkoxyresorufin o-dealkylation in human and rat liver. Biochem. Pharmacol. 48 5 (1994) 923-936
    • (1994) Biochem. Pharmacol. , vol.48 , Issue.5 , pp. 923-936
    • Burke, M.D.1    Thompson, S.2    Weaver, R.J.3    Wolf, C.R.4    Mayer, R.T.5
  • 31
    • 0020787408 scopus 로고
    • A sensitive and specific stable isotope assy for warfarin and its metabolites
    • Bush E.D., Low L.K., and Trager W.F. A sensitive and specific stable isotope assy for warfarin and its metabolites. Biomed. Mass Spectrom. 10 7 (1983) 395-398
    • (1983) Biomed. Mass Spectrom. , vol.10 , Issue.7 , pp. 395-398
    • Bush, E.D.1    Low, L.K.2    Trager, W.F.3
  • 32
    • 0018824051 scopus 로고
    • Glucuronidation of digitalis glycosides by rat liver microsomes: Stimulation by spironolactone and pregnenolone-16;ga-carbonitrile
    • Castle M.C. Glucuronidation of digitalis glycosides by rat liver microsomes: Stimulation by spironolactone and pregnenolone-16;ga-carbonitrile. Biochem. Pharmacol. 29 (1980) 1497-1502
    • (1980) Biochem. Pharmacol. , vol.29 , pp. 1497-1502
    • Castle, M.C.1
  • 33
    • 0017594533 scopus 로고
    • Enzymatic sulfation of bile salts. Partial purification and characterization of an enzyme from rat liver that catalyzes the sulfation of bile salts
    • Chen L.J., Bolt R.J., and Admirand W.H. Enzymatic sulfation of bile salts. Partial purification and characterization of an enzyme from rat liver that catalyzes the sulfation of bile salts. Biochim. Biophys. Acta 480 (1977) 219-227
    • (1977) Biochim. Biophys. Acta , vol.480 , pp. 219-227
    • Chen, L.J.1    Bolt, R.J.2    Admirand, W.H.3
  • 34
    • 0014125542 scopus 로고
    • Pharmacological implications of microsomal enzyme induction
    • Conney A.H. Pharmacological implications of microsomal enzyme induction. Pharmacol. Rev. 19 3 (1967) 317-366
    • (1967) Pharmacol. Rev. , vol.19 , Issue.3 , pp. 317-366
    • Conney, A.H.1
  • 36
    • 0029024968 scopus 로고
    • Relative potencies of induction of hepatic drug-metabolizing enzyme genes by individual PCB congeners
    • Dragnev K.H., Nims R.W., Fox S.D., Lindahl R., and Lubet R.A. Relative potencies of induction of hepatic drug-metabolizing enzyme genes by individual PCB congeners. Toxicol. Appl. Pharmacol. 132 2 (1995) 334-342
    • (1995) Toxicol. Appl. Pharmacol. , vol.132 , Issue.2 , pp. 334-342
    • Dragnev, K.H.1    Nims, R.W.2    Fox, S.D.3    Lindahl, R.4    Lubet, R.A.5
  • 37
    • 0023722925 scopus 로고
    • Differential gene expression in response to 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD). Noncoordinate regulation of a TCDD-induced aldehyde dehydrogenase and cytochrome P-450c in the rat
    • Dunn T.J., Lindahl R., and Pitot H.C. Differential gene expression in response to 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD). Noncoordinate regulation of a TCDD-induced aldehyde dehydrogenase and cytochrome P-450c in the rat. J. Biol. Chem. 263 22 (1988) 10878-10886
    • (1988) J. Biol. Chem. , vol.263 , Issue.22 , pp. 10878-10886
    • Dunn, T.J.1    Lindahl, R.2    Pitot, H.C.3
  • 38
    • 0022968251 scopus 로고
    • Induction of mixed function oxidase activity in man by rifapentine (MDL 473), a long-acting rifamycin derivative
    • Durand D., Hampden C., Boobis A.R., Park B.K., and Davies D.S. Induction of mixed function oxidase activity in man by rifapentine (MDL 473), a long-acting rifamycin derivative. Br. J. Clin. Pharmacol. 21 (1986) 1-7
    • (1986) Br. J. Clin. Pharmacol. , vol.21 , pp. 1-7
    • Durand, D.1    Hampden, C.2    Boobis, A.R.3    Park, B.K.4    Davies, D.S.5
  • 39
    • 0024559081 scopus 로고
    • Reduction of 7-alkoxyresorufins by NADPH-cytochrome P450 reductase and its differential effects on their O-dealkylation by rat liver microsomal cytochrome P450
    • Dutton D.R., and Parkinson A. Reduction of 7-alkoxyresorufins by NADPH-cytochrome P450 reductase and its differential effects on their O-dealkylation by rat liver microsomal cytochrome P450. Arch. Biochem. Biophys. 268 (1989) 617-629
    • (1989) Arch. Biochem. Biophys. , vol.268 , pp. 617-629
    • Dutton, D.R.1    Parkinson, A.2
  • 40
    • 0029683112 scopus 로고    scopus 로고
    • Antipyrine as a probe for human oxidative drug metabolism: Identification of the cytochrome P450 enzymes catalyzing 4-hydroxyantipyrine, 3-hydroxymethylantipyrine, and norantipyrine formation
    • Engel G., Hofmann U., Heidemann H., Cosme J., and Eichelbaum M. Antipyrine as a probe for human oxidative drug metabolism: Identification of the cytochrome P450 enzymes catalyzing 4-hydroxyantipyrine, 3-hydroxymethylantipyrine, and norantipyrine formation. Clin. Pharmacol. Ther. 59 (1996) 613-623
    • (1996) Clin. Pharmacol. Ther. , vol.59 , pp. 613-623
    • Engel, G.1    Hofmann, U.2    Heidemann, H.3    Cosme, J.4    Eichelbaum, M.5
  • 41
    • 0025316892 scopus 로고
    • Human cytochrome P450 Isoforms-their genetic heterogeneity and induction by omeprazole
    • Farrell G.C., and Murray M. Human cytochrome P450 Isoforms-their genetic heterogeneity and induction by omeprazole. Gastroenterology 99 (1990) 885-889
    • (1990) Gastroenterology , vol.99 , pp. 885-889
    • Farrell, G.C.1    Murray, M.2
  • 42
    • 0025986720 scopus 로고
    • Oral contraceptive drug interactions: Important considerations (see comments) (review)
    • Fazio A. Oral contraceptive drug interactions: Important considerations (see comments) (review). South. Med. J. 84 8 (1991) 997-1002
    • (1991) South. Med. J. , vol.84 , Issue.8 , pp. 997-1002
    • Fazio, A.1
  • 43
    • 0028937507 scopus 로고
    • Phenytoin causes a rapid increase in 6;gb-hydroxycortisol urinary excretion in humans-a putative measure of CYP3A induction
    • Fleishaker J.C., Pearson L.K., and Peters G.R. Phenytoin causes a rapid increase in 6;gb-hydroxycortisol urinary excretion in humans-a putative measure of CYP3A induction. J. Pharm. Sci. 84 3 (1995) 292-294
    • (1995) J. Pharm. Sci. , vol.84 , Issue.3 , pp. 292-294
    • Fleishaker, J.C.1    Pearson, L.K.2    Peters, G.R.3
  • 44
    • 0028942623 scopus 로고
    • Microsomal enzyme inducers raise plasma high-density lipoprotein cholesterol levels in healthy control subjects but not in patients with primary hypoalphalipoproteinemia
    • Franceschini G., D'Werba J.P., Acquarica A.L., Gianfranceshi G., Michelagnoli S., and Sirtori C.R. Microsomal enzyme inducers raise plasma high-density lipoprotein cholesterol levels in healthy control subjects but not in patients with primary hypoalphalipoproteinemia. Clin. Pharmacol. Ther. 57 (1995) 434-440
    • (1995) Clin. Pharmacol. Ther. , vol.57 , pp. 434-440
    • Franceschini, G.1    D'Werba, J.P.2    Acquarica, A.L.3    Gianfranceshi, G.4    Michelagnoli, S.5    Sirtori, C.R.6
  • 45
    • 0026584261 scopus 로고
    • Differentiation of cytochrome P-450 inducers on the basis of 7-alkoxycoumarin O-dealkylase activities
    • Fry J.R., Garle M.J., and Lal K. Differentiation of cytochrome P-450 inducers on the basis of 7-alkoxycoumarin O-dealkylase activities. Xenobiotica 22 2 (1992) 211-215
    • (1992) Xenobiotica , vol.22 , Issue.2 , pp. 211-215
    • Fry, J.R.1    Garle, M.J.2    Lal, K.3
  • 47
    • 0025755576 scopus 로고
    • Induction of drug-metabolizing enzymes
    • Gibaldi M. Induction of drug-metabolizing enzymes. Perspect. Clin. Pharm. 9 6 (1991) 41-46
    • (1991) Perspect. Clin. Pharm. , vol.9 , Issue.6 , pp. 41-46
    • Gibaldi, M.1
  • 48
    • 0025827880 scopus 로고
    • Inducing effect of oxfendazole on cytochrome P4501A2 in rabbit liver. Consequences on cytochrome P450 dependent monooxygenases
    • Gleizes C., Eeckhoutte C., Pineau T., Alvinerie M., and Galtier P. Inducing effect of oxfendazole on cytochrome P4501A2 in rabbit liver. Consequences on cytochrome P450 dependent monooxygenases. Biochem. Pharmacol. 41 12 (1991) 1813-1820
    • (1991) Biochem. Pharmacol. , vol.41 , Issue.12 , pp. 1813-1820
    • Gleizes, C.1    Eeckhoutte, C.2    Pineau, T.3    Alvinerie, M.4    Galtier, P.5
  • 49
    • 0018092881 scopus 로고
    • Genetic variation in N-acetylation of carcinogenic arylamines by human and rabbit liver
    • Glowinski I.B., Radtke H.E., and Weber W.W. Genetic variation in N-acetylation of carcinogenic arylamines by human and rabbit liver. Mol. Pharmacol. 14 (1978) 940-949
    • (1978) Mol. Pharmacol. , vol.14 , pp. 940-949
    • Glowinski, I.B.1    Radtke, H.E.2    Weber, W.W.3
  • 50
    • 0018933224 scopus 로고
    • The expanding role of microsomal enzyme induction, and its implications for clinical chemistry
    • Goldberg D.M. The expanding role of microsomal enzyme induction, and its implications for clinical chemistry. Clin. Chem. 26 6 (1980) 691-699
    • (1980) Clin. Chem. , vol.26 , Issue.6 , pp. 691-699
    • Goldberg, D.M.1
  • 51
    • 0028272001 scopus 로고
    • Role of human cytochromes P450 in the metabolic activation of chemical carcinogens and toxins
    • Gonzalez F.J., and Gelboin H.V. Role of human cytochromes P450 in the metabolic activation of chemical carcinogens and toxins. Drug Metab. Rev. 26 1&2 (1994) 165-183
    • (1994) Drug Metab. Rev. , vol.26 , Issue.1-2 , pp. 165-183
    • Gonzalez, F.J.1    Gelboin, H.V.2
  • 52
    • 0027409436 scopus 로고
    • Regulation of cytochrome P450 genes: Molecular mechanisms
    • Liu Gonzalez F.J., and Yano S.Y.M. Regulation of cytochrome P450 genes: Molecular mechanisms. Pharmacogenetics 3 (1993) 51-57
    • (1993) Pharmacogenetics , vol.3 , pp. 51-57
    • Liu Gonzalez, F.J.1    Yano, S.Y.M.2
  • 53
    • 0028031172 scopus 로고
    • Clinically significant drug interactions with antituberculosis agents
    • Grange J.M., Winstanley P.A., and Davies P.D.O. Clinically significant drug interactions with antituberculosis agents. Drug Saf. 11 4 (1994) 242-251
    • (1994) Drug Saf. , vol.11 , Issue.4 , pp. 242-251
    • Grange, J.M.1    Winstanley, P.A.2    Davies, P.D.O.3
  • 54
    • 0025878351 scopus 로고
    • Role of persistent, non-genotoxic tissue damage in rodent cancer and relevance to humans
    • Grasso P., Sharratt M., and Cohen A.J. Role of persistent, non-genotoxic tissue damage in rodent cancer and relevance to humans. Annu. Rev. Pharmacol. Toxicol. 31 (1991) 253-287
    • (1991) Annu. Rev. Pharmacol. Toxicol. , vol.31 , pp. 253-287
    • Grasso, P.1    Sharratt, M.2    Cohen, A.J.3
  • 55
    • 0028965804 scopus 로고
    • Activity of hepatic drug metabolizing enzymes following oxazepam-dosed feed treatment in B6C3F1 mice
    • Griffin R.J., Burka L.T., and Cunningham M.L. Activity of hepatic drug metabolizing enzymes following oxazepam-dosed feed treatment in B6C3F1 mice. Toxicol. Lett. 76 (1995) 251-256
    • (1995) Toxicol. Lett. , vol.76 , pp. 251-256
    • Griffin, R.J.1    Burka, L.T.2    Cunningham, M.L.3
  • 56
    • 0020028678 scopus 로고
    • Estimation of isozymes of microsomal cytochrome P-450 in rats, rabbits, and humans using immunochemical staining coupled with sodium dodecyl sulfate-polyacrylamide gel electrophoresis
    • Guengerich F.P., Wang P., and Davidson N.K. Estimation of isozymes of microsomal cytochrome P-450 in rats, rabbits, and humans using immunochemical staining coupled with sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Biochemistry 21 (1982) 1698-1706
    • (1982) Biochemistry , vol.21 , pp. 1698-1706
    • Guengerich, F.P.1    Wang, P.2    Davidson, N.K.3
  • 57
    • 0016275313 scopus 로고
    • Glutathione transferases: The first step in mercapturic acid formation
    • Habig W.H., Pabst M.J., and Jakoby W.B. Glutathione transferases: The first step in mercapturic acid formation. J. Biol. Chem. 249 (1974) 7130-7139
    • (1974) J. Biol. Chem. , vol.249 , pp. 7130-7139
    • Habig, W.H.1    Pabst, M.J.2    Jakoby, W.B.3
  • 58
    • 0015597281 scopus 로고
    • Multiple N-acetyltransferases and drug metabolism, tissue distribution, characterization and significance of mammalian N-acetyltransferase
    • Hearse D.J., and Weber W.W. Multiple N-acetyltransferases and drug metabolism, tissue distribution, characterization and significance of mammalian N-acetyltransferase. Biochem. J. 132 (1973) 519-526
    • (1973) Biochem. J. , vol.132 , pp. 519-526
    • Hearse, D.J.1    Weber, W.W.2
  • 59
    • 0000747053 scopus 로고
    • Carboxylesterases and amidases
    • Jakoby W.B. (Ed), Academic Press, New York
    • Heymann E. Carboxylesterases and amidases. In: Jakoby W.B. (Ed). "Enzymatic Basis of Detoxication" 2 (1980), Academic Press, New York 291-323
    • (1980) "Enzymatic Basis of Detoxication" , vol.2 , pp. 291-323
    • Heymann, E.1
  • 60
    • 0018863127 scopus 로고
    • Effect of administration route of 3-methylcholanthrene on the inducibility of intestinal drug-metabolizing enzymes
    • Hietanen E., Laitinen M., and Koivusaari U. Effect of administration route of 3-methylcholanthrene on the inducibility of intestinal drug-metabolizing enzymes. Enzyme 25 (1980) 153-157
    • (1980) Enzyme , vol.25 , pp. 153-157
    • Hietanen, E.1    Laitinen, M.2    Koivusaari, U.3
  • 62
    • 0023180455 scopus 로고
    • Multiplicity and regulation of hepatic microsomal carboxylesterases in rats
    • Hosokawa M., Maki T., and Satoh T. Multiplicity and regulation of hepatic microsomal carboxylesterases in rats. Mol. Pharmacol. 31 (1987) 579-584
    • (1987) Mol. Pharmacol. , vol.31 , pp. 579-584
    • Hosokawa, M.1    Maki, T.2    Satoh, T.3
  • 63
    • 0025261405 scopus 로고
    • Characterization of molecular species of liver microsomal carboxylesterases of several animal species and humans
    • Hosokawa M., Maki T., and Satoh T. Characterization of molecular species of liver microsomal carboxylesterases of several animal species and humans. Arch. Biochem. Biophys. 277 (1990) 219-227
    • (1990) Arch. Biochem. Biophys. , vol.277 , pp. 219-227
    • Hosokawa, M.1    Maki, T.2    Satoh, T.3
  • 64
    • 0028072775 scopus 로고
    • Species differences in the induction of hepatic microsomal carboxylesterases caused by dietary exposure to di(2-ethlhexyl)phthalate, a peroxisome proliferator
    • Hosokawa M., Hirata K., Nakata F., Suga T., and Satoh T. Species differences in the induction of hepatic microsomal carboxylesterases caused by dietary exposure to di(2-ethlhexyl)phthalate, a peroxisome proliferator. Drug Metab. Dispos. 22 6 (1994) 889-894
    • (1994) Drug Metab. Dispos. , vol.22 , Issue.6 , pp. 889-894
    • Hosokawa, M.1    Hirata, K.2    Nakata, F.3    Suga, T.4    Satoh, T.5
  • 65
    • 0025741754 scopus 로고
    • Comparative biochemical and morphometric changes associated with induction of the hepatic mixed function oxidase system in the rat
    • Howard M.O., Schwartz L.W., Newton J.F., Qualls C.W., Yodis L.A.P., and Ventre J.R. Comparative biochemical and morphometric changes associated with induction of the hepatic mixed function oxidase system in the rat. Toxicol. Pathol. 19 2 (1991) 115-122
    • (1991) Toxicol. Pathol. , vol.19 , Issue.2 , pp. 115-122
    • Howard, M.O.1    Schwartz, L.W.2    Newton, J.F.3    Qualls, C.W.4    Yodis, L.A.P.5    Ventre, J.R.6
  • 66
    • 0026691486 scopus 로고
    • Studies on the biochemical effects of the aldose reductase inhibitor 2, 7-difluorospirofluorene- 9, 5′-imidazolidine-2′, 4′-dione (A1 1576, HOE 843). Detection of D-glucaric and D-glucuronic acid excretion by high resolution 1H and 13C NMR spectroscopy
    • Hoyle V.R., Gilbert P.J., Troke J.A., Vose C.W., and Nicholson J.K. Studies on the biochemical effects of the aldose reductase inhibitor 2, 7-difluorospirofluorene- 9, 5′-imidazolidine-2′, 4′-dione (A1 1576, HOE 843). Detection of D-glucaric and D-glucuronic acid excretion by high resolution 1H and 13C NMR spectroscopy. Biochem. Pharmacol. 44 2 (1992) 231-241
    • (1992) Biochem. Pharmacol. , vol.44 , Issue.2 , pp. 231-241
    • Hoyle, V.R.1    Gilbert, P.J.2    Troke, J.A.3    Vose, C.W.4    Nicholson, J.K.5
  • 67
    • 0015233470 scopus 로고
    • Urinary D-glucaric-acid excretion as a test for hepatic enzyme induction in man
    • Hunter J., Maxwell J.D., Carrella M., Stewart D.A., and Williams R. Urinary D-glucaric-acid excretion as a test for hepatic enzyme induction in man. Lancet 1 699 (1971) 572-575
    • (1971) Lancet , vol.1 , Issue.699 , pp. 572-575
    • Hunter, J.1    Maxwell, J.D.2    Carrella, M.3    Stewart, D.A.4    Williams, R.5
  • 68
    • 0023706607 scopus 로고
    • Aminopyrine metabolism by multiple forms of cytochrome P-450 from rat liver microsomes: Simultaneous quantitation of four aminopyrine metabolites by high-performance liquid chromatography
    • Imaoka S., Inoue K., and Funae Y. Aminopyrine metabolism by multiple forms of cytochrome P-450 from rat liver microsomes: Simultaneous quantitation of four aminopyrine metabolites by high-performance liquid chromatography. Arch. Biochem. Biophys. 265 1 (1988) 159-170
    • (1988) Arch. Biochem. Biophys. , vol.265 , Issue.1 , pp. 159-170
    • Imaoka, S.1    Inoue, K.2    Funae, Y.3
  • 69
    • 0028138480 scopus 로고
    • Simultaneous high performance liquid chromatographic determination of 6β-hydroxycortisol and cortisol in urine with fluorescence detection and its application for estimating hepatic drug-metabolizing enzyme induction
    • Inoue S., Inokuma M., Harada T., Shibutani Y., Yoshitake T., Charles B., Ishida J., and Yamaguchi M. Simultaneous high performance liquid chromatographic determination of 6β-hydroxycortisol and cortisol in urine with fluorescence detection and its application for estimating hepatic drug-metabolizing enzyme induction. J. Chromatogr. B: Biomed. Appl. 661 (1994) 15-23
    • (1994) J. Chromatogr. B: Biomed. Appl. , vol.661 , pp. 15-23
    • Inoue, S.1    Inokuma, M.2    Harada, T.3    Shibutani, Y.4    Yoshitake, T.5    Charles, B.6    Ishida, J.7    Yamaguchi, M.8
  • 70
    • 0023522162 scopus 로고
    • Commentary: The cytochromes P-448-a unique family of enzymes involved in chemical toxicity and carcinogenesis
    • Ioannides C., and Parke D.V. Commentary: The cytochromes P-448-a unique family of enzymes involved in chemical toxicity and carcinogenesis. Biochem. Pharmacol. 36 24 (1987) 4197-4207
    • (1987) Biochem. Pharmacol. , vol.36 , Issue.24 , pp. 4197-4207
    • Ioannides, C.1    Parke, D.V.2
  • 71
    • 0027751340 scopus 로고
    • Induction of cytochrome P4501 as an indicator of potential chemical carcinogenesis
    • Ioannides C., and Parke D.V. Induction of cytochrome P4501 as an indicator of potential chemical carcinogenesis. Drug Metab. Rev. 25 4 (1993) 485-501
    • (1993) Drug Metab. Rev. , vol.25 , Issue.4 , pp. 485-501
    • Ioannides, C.1    Parke, D.V.2
  • 72
    • 0027970864 scopus 로고
    • Liver enzyme induction and serum lipid levels after replacement of carbamazepine with oxcarbazepine
    • Isojärvi J.I.T., Pakarinen A.J., Rautio A., Pelkonen O., and Myllylä V.V. Liver enzyme induction and serum lipid levels after replacement of carbamazepine with oxcarbazepine. Epilepsia 35 6 (1994) 1217-1220
    • (1994) Epilepsia , vol.35 , Issue.6 , pp. 1217-1220
    • Isojärvi, J.I.T.1    Pakarinen, A.J.2    Rautio, A.3    Pelkonen, O.4    Myllylä, V.V.5
  • 73
    • 0021922120 scopus 로고
    • Microsomal cytochrome P-450 "handprints": Five fractions from anion-exchange high-pressure liquid chromatography provide a rapid preliminary screen for selectivity in the induction and destruction of rat hepatic cytochrome P-450 subpopulations
    • Iversen P.L., and Franklin M.R. Microsomal cytochrome P-450 "handprints": Five fractions from anion-exchange high-pressure liquid chromatography provide a rapid preliminary screen for selectivity in the induction and destruction of rat hepatic cytochrome P-450 subpopulations. Toxicol. Appl. Pharmacol. 78 (1985) 1-9
    • (1985) Toxicol. Appl. Pharmacol. , vol.78 , pp. 1-9
    • Iversen, P.L.1    Franklin, M.R.2
  • 74
    • 0025872863 scopus 로고
    • Identification of the cytochrome P-450 IIIA family as the enzymes involved in the N-demethylation of tamoxifen in human liver microsomes
    • Jacolot F., Simon I., Dreano Y., Beaune P., Riche C., and Berthou F. Identification of the cytochrome P-450 IIIA family as the enzymes involved in the N-demethylation of tamoxifen in human liver microsomes. Biochem. Pharmacol. 41 (1991) 1911-1919
    • (1991) Biochem. Pharmacol. , vol.41 , pp. 1911-1919
    • Jacolot, F.1    Simon, I.2    Dreano, Y.3    Beaune, P.4    Riche, C.5    Berthou, F.6
  • 75
    • 0026907361 scopus 로고
    • Induction of various cytochromes CYP2B, CYP2C and CYP3A by phenobarbitone in non-human primates
    • Jones C.R., Guengerich F.P., Rice J.M., and Lubet R.A. Induction of various cytochromes CYP2B, CYP2C and CYP3A by phenobarbitone in non-human primates. Pharmacogenetics 2 (1992) 160-172
    • (1992) Pharmacogenetics , vol.2 , pp. 160-172
    • Jones, C.R.1    Guengerich, F.P.2    Rice, J.M.3    Lubet, R.A.4
  • 76
    • 0025969276 scopus 로고
    • Caffeine as a metabolic probe: Exploration of the enzymeinducing effect of cigarette smoking
    • Kalow W., and Tang B.K. Caffeine as a metabolic probe: Exploration of the enzymeinducing effect of cigarette smoking. Clin. Pharmacol. Ther. 49 (1991) 44-48
    • (1991) Clin. Pharmacol. Ther. , vol.49 , pp. 44-48
    • Kalow, W.1    Tang, B.K.2
  • 78
    • 0027159323 scopus 로고
    • Single-dose disulfiram inhibition of chlorzoxazone metabolism: A clinical probe for P450 2E1
    • Kharasch E.D., Thummel K.E., Mhyre J., and Lillibridge J.H. Single-dose disulfiram inhibition of chlorzoxazone metabolism: A clinical probe for P450 2E1. Clin. Pharmacol. Ther. 53 6 (1993) 643-650
    • (1993) Clin. Pharmacol. Ther. , vol.53 , Issue.6 , pp. 643-650
    • Kharasch, E.D.1    Thummel, K.E.2    Mhyre, J.3    Lillibridge, J.H.4
  • 79
    • 0028918996 scopus 로고
    • Comparative analysis of cytochrome P4503A induction in primary cultures of rat, rabbit, and human hepatocytes
    • Kocarek T.A., Schuetz E.G., Strom S.C., Fisher R.A., and Guzelian P.S. Comparative analysis of cytochrome P4503A induction in primary cultures of rat, rabbit, and human hepatocytes. Drug Metab. Dispos. 23 3 (1995) 415-421
    • (1995) Drug Metab. Dispos. , vol.23 , Issue.3 , pp. 415-421
    • Kocarek, T.A.1    Schuetz, E.G.2    Strom, S.C.3    Fisher, R.A.4    Guzelian, P.S.5
  • 80
    • 0022494453 scopus 로고
    • Hydroxylation of para-nitrophenol by rabbit ethanol inducible cytochrome P-450 isozyme 3A
    • Koop D.R. Hydroxylation of para-nitrophenol by rabbit ethanol inducible cytochrome P-450 isozyme 3A. Mol. Pharmacol. 29 (1986) 399-404
    • (1986) Mol. Pharmacol. , vol.29 , pp. 399-404
    • Koop, D.R.1
  • 83
    • 0022511846 scopus 로고
    • Use of a low-speed iso-density Percoll centrifugation method to increase the viability of isolated hepatocyte preparations
    • Kreamer B.L., Staecker J.L., Sawada N., Sattler G.L., Hsia M.T.S., and Pitot H.C. Use of a low-speed iso-density Percoll centrifugation method to increase the viability of isolated hepatocyte preparations. In Vitro 22 (1986) 201
    • (1986) In Vitro , vol.22 , pp. 201
    • Kreamer, B.L.1    Staecker, J.L.2    Sawada, N.3    Sattler, G.L.4    Hsia, M.T.S.5    Pitot, H.C.6
  • 84
    • 0026724265 scopus 로고
    • Autoinduction and steady-state pharmacokinetics of carbamazepine and its major metabolites
    • Kudriakova T.B., Sirota L.A., Rozova G.I., and Gorkov V.A. Autoinduction and steady-state pharmacokinetics of carbamazepine and its major metabolites. Br. J. Clin. Pharmacol. 33 (1992) 611-615
    • (1992) Br. J. Clin. Pharmacol. , vol.33 , pp. 611-615
    • Kudriakova, T.B.1    Sirota, L.A.2    Rozova, G.I.3    Gorkov, V.A.4
  • 85
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (London) 227 (1970) 680-685
    • (1970) Nature (London) , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 86
  • 87
    • 0020624033 scopus 로고
    • Induction of hepatic drug-metabolizing enzymes in rats, dogs, and monkeys after repeated administration of an anti-inflammatory hexahydroindazole
    • Lan S.J., Weinstein S.H., Keim G.R., and Migdalof B.H. Induction of hepatic drug-metabolizing enzymes in rats, dogs, and monkeys after repeated administration of an anti-inflammatory hexahydroindazole. Xenobiotica 13 6 (1983) 329-335
    • (1983) Xenobiotica , vol.13 , Issue.6 , pp. 329-335
    • Lan, S.J.1    Weinstein, S.H.2    Keim, G.R.3    Migdalof, B.H.4
  • 88
    • 0022649901 scopus 로고
    • Drug pharmacokinetics and the carbon dioxide breath test
    • Lane E.A., and Parashos I. Drug pharmacokinetics and the carbon dioxide breath test. J. Pharmacokinet. Biopharm. 14 1 (1986) 29-49
    • (1986) J. Pharmacokinet. Biopharm. , vol.14 , Issue.1 , pp. 29-49
    • Lane, E.A.1    Parashos, I.2
  • 90
    • 0029021932 scopus 로고
    • Rifampincin induction of lidocaine metabolism in cultured human hepatocytes
    • Li A.P., Rasmussen A., Xu L., and Kaminiski D.L. Rifampincin induction of lidocaine metabolism in cultured human hepatocytes. J. Pharmacol. Exp. Ther. 274 (1995) 673-677
    • (1995) J. Pharmacol. Exp. Ther. , vol.274 , pp. 673-677
    • Li, A.P.1    Rasmussen, A.2    Xu, L.3    Kaminiski, D.L.4
  • 91
    • 0029584276 scopus 로고
    • Substrates of human hepatic cytochrome P450 3A4
    • Li A.P., Kaminski D.L., and Rasmussen A. Substrates of human hepatic cytochrome P450 3A4. Toxicology 104 (1995) 1-8
    • (1995) Toxicology , vol.104 , pp. 1-8
    • Li, A.P.1    Kaminski, D.L.2    Rasmussen, A.3
  • 94
    • 0022350885 scopus 로고
    • Dealkylation of pentoxyresorufin: A rapid and sensitive assay for measuring induction of cytochrome(s) P-450 by phenobarbital and other xenobiotics in the rat
    • Lubet R.A., Mayer R.T., Cameron J.W., Nims R.W., Burke M.D., Wolff T., and Guengerich F.P. Dealkylation of pentoxyresorufin: A rapid and sensitive assay for measuring induction of cytochrome(s) P-450 by phenobarbital and other xenobiotics in the rat. Arch. Biochem. Biophys. 238 1 (1985) 43-48
    • (1985) Arch. Biochem. Biophys. , vol.238 , Issue.1 , pp. 43-48
    • Lubet, R.A.1    Mayer, R.T.2    Cameron, J.W.3    Nims, R.W.4    Burke, M.D.5    Wolff, T.6    Guengerich, F.P.7
  • 95
    • 0024524508 scopus 로고
    • Induction of cytochrome P450b and its relationship to liver tumor promotion
    • Lubet R.A., Nims R.W., Ward J.M., Rice J.M., and Diwan B.A. Induction of cytochrome P450b and its relationship to liver tumor promotion. J. Am. Coll. Toxicol. 8 2 (1989) 259-268
    • (1989) J. Am. Coll. Toxicol. , vol.8 , Issue.2 , pp. 259-268
    • Lubet, R.A.1    Nims, R.W.2    Ward, J.M.3    Rice, J.M.4    Diwan, B.A.5
  • 96
    • 0023940612 scopus 로고
    • Microsomal enzyme induction, lipoproteins and atherosclerosis
    • Luoma P.V. Microsomal enzyme induction, lipoproteins and atherosclerosis. Pharmacol. Toxicol. 62 (1988) 243-249
    • (1988) Pharmacol. Toxicol. , vol.62 , pp. 243-249
    • Luoma, P.V.1
  • 97
    • 0019969512 scopus 로고
    • Preparation of human hepatocytes from primary culture
    • Maekubo H., Ozaki S., Mitmaker B., and Kalant N. Preparation of human hepatocytes from primary culture. In Vitro 18 (1982) 483-491
    • (1982) In Vitro , vol.18 , pp. 483-491
    • Maekubo, H.1    Ozaki, S.2    Mitmaker, B.3    Kalant, N.4
  • 98
    • 0030028139 scopus 로고    scopus 로고
    • In vivo induction of cytochrome P450 CYP3A expression in rat leukocytes using various inducers
    • Mahnke A., Roos P.H., Hanstein W.G., and Chabot G.G. In vivo induction of cytochrome P450 CYP3A expression in rat leukocytes using various inducers. Biochem. Pharmacol. 51 (1996) 1579-1582
    • (1996) Biochem. Pharmacol. , vol.51 , pp. 1579-1582
    • Mahnke, A.1    Roos, P.H.2    Hanstein, W.G.3    Chabot, G.G.4
  • 99
    • 0003009327 scopus 로고
    • Experiments illustrating drug metabolism in vitro
    • LaDu B.N., Mandel H.G., and Way E.L. (Eds), Williams & Wilkins, Baltimore
    • Mazel P. Experiments illustrating drug metabolism in vitro. In: LaDu B.N., Mandel H.G., and Way E.L. (Eds). "Fundamentals of Drug Metabolism and Disposition" (1971), Williams & Wilkins, Baltimore 546-550
    • (1971) "Fundamentals of Drug Metabolism and Disposition" , pp. 546-550
    • Mazel, P.1
  • 100
    • 0023785943 scopus 로고
    • Drug interactions that matter. A critical reappraisal
    • McInnes G.T., and Brodie M.J. Drug interactions that matter. A critical reappraisal. Drugs 36 (1988) 83-110
    • (1988) Drugs , vol.36 , pp. 83-110
    • McInnes, G.T.1    Brodie, M.J.2
  • 101
    • 0022384124 scopus 로고
    • Effects of phenobarbitone and β-naphthoflavone on hepatic microsomal drug metabolising enzymes of the male beagle dog
    • McKillop D. Effects of phenobarbitone and β-naphthoflavone on hepatic microsomal drug metabolising enzymes of the male beagle dog. Biochem. Pharmacol. 34 17 (1985) 3137-3142
    • (1985) Biochem. Pharmacol. , vol.34 , Issue.17 , pp. 3137-3142
    • McKillop, D.1
  • 102
    • 84973743864 scopus 로고
    • Is enzyme induction good for you? A problem of epidemiology and toxicology
    • McLean A.E.M. Is enzyme induction good for you? A problem of epidemiology and toxicology. Hum. Toxicol. 7 (1988) 419-422
    • (1988) Hum. Toxicol. , vol.7 , pp. 419-422
    • McLean, A.E.M.1
  • 104
    • 77049138167 scopus 로고
    • The colorimetric estimation of formaldehyde by means of the Hantzsch reaction
    • Nash T. The colorimetric estimation of formaldehyde by means of the Hantzsch reaction. J. Biol. Chem. 55 (1953) 416-421
    • (1953) J. Biol. Chem. , vol.55 , pp. 416-421
    • Nash, T.1
  • 105
    • 0018680603 scopus 로고
    • Multiple forms of inducible drug-metabolizing enzymes: A reasonable mechanism by which any organism can cope with adversity
    • Nebert D.W. Multiple forms of inducible drug-metabolizing enzymes: A reasonable mechanism by which any organism can cope with adversity. Mol. Cell. Biochem. 27 1 (1979) 27-46
    • (1979) Mol. Cell. Biochem. , vol.27 , Issue.1 , pp. 27-46
    • Nebert, D.W.1
  • 106
    • 0028662025 scopus 로고
    • P450 in the rat and man: Methods of investigation, substrate specificities and relevance to cancer
    • Nedelcheva V., and Gut I. P450 in the rat and man: Methods of investigation, substrate specificities and relevance to cancer. Xenobiotica 24 12 (1994) 1151-1175
    • (1994) Xenobiotica , vol.24 , Issue.12 , pp. 1151-1175
    • Nedelcheva, V.1    Gut, I.2
  • 107
    • 0028960240 scopus 로고
    • Comparative metabolism of 3′-azido-3′-deoxythymidine in cultured hepatocytes from rats, dogs, monkeys, and humans
    • Nicolas F., De Sousa G., Thomas P., Placidi M., Lorenzon G., and Rahmani R. Comparative metabolism of 3′-azido-3′-deoxythymidine in cultured hepatocytes from rats, dogs, monkeys, and humans. Drug Metab. Dispos. 23 3 (1995) 308-313
    • (1995) Drug Metab. Dispos. , vol.23 , Issue.3 , pp. 308-313
    • Nicolas, F.1    De Sousa, G.2    Thomas, P.3    Placidi, M.4    Lorenzon, G.5    Rahmani, R.6
  • 108
    • 0027092472 scopus 로고
    • Induction of hepatic CYP1A in male F344/NCr rats by dietary exposure to Aroclor 1254: Examination of immunochemical, RNA, catalytic, and pharmacokinetic endpoints
    • Nims R.W., Beebe L.E., Dragnev K.H., Thomas P.E., Fox S.D., Issaq H.J., Jones C.R., and Lubet R.A. Induction of hepatic CYP1A in male F344/NCr rats by dietary exposure to Aroclor 1254: Examination of immunochemical, RNA, catalytic, and pharmacokinetic endpoints. Environ. Res. 59 2 (1992) 447-466
    • (1992) Environ. Res. , vol.59 , Issue.2 , pp. 447-466
    • Nims, R.W.1    Beebe, L.E.2    Dragnev, K.H.3    Thomas, P.E.4    Fox, S.D.5    Issaq, H.J.6    Jones, C.R.7    Lubet, R.A.8
  • 109
    • 0015217363 scopus 로고
    • A radiometric assay for hepatic epoxide hydrase activity with {7-3H}styrene oxide
    • Oesch F., Jerina D.M., and Daly J. A radiometric assay for hepatic epoxide hydrase activity with {7-3H}styrene oxide. Biochim. Biophys. Acta 227 (1971) 685-691
    • (1971) Biochim. Biophys. Acta , vol.227 , pp. 685-691
    • Oesch, F.1    Jerina, D.M.2    Daly, J.3
  • 110
    • 0018386160 scopus 로고
    • Measurement of urinary 6-;gb-hydroxycortisol excretion as an in vivo parameter in the clinical assessment of the microsomal enzyme-inducing capacity of antipyrine, phenobarbitone and rifampicin
    • Ohnhaus E.E., and Park B.K. Measurement of urinary 6-;gb-hydroxycortisol excretion as an in vivo parameter in the clinical assessment of the microsomal enzyme-inducing capacity of antipyrine, phenobarbitone and rifampicin. Eur. J. Pharmacol. 15 2 (1979) 139-145
    • (1979) Eur. J. Pharmacol. , vol.15 , Issue.2 , pp. 139-145
    • Ohnhaus, E.E.1    Park, B.K.2
  • 111
    • 0025055648 scopus 로고
    • Enzyme induction in the cytochrome P-450 system
    • Okey A.B. Enzyme induction in the cytochrome P-450 system. Pharmacol. Ther. 45 (1990) 241-298
    • (1990) Pharmacol. Ther. , vol.45 , pp. 241-298
    • Okey, A.B.1
  • 112
    • 0022472879 scopus 로고
    • Induction of drugmetabolising enzymes: Mechanisms and consequences
    • Okey A.B., Roberts E.A., Harper P.A., and Denison M.S. Induction of drugmetabolising enzymes: Mechanisms and consequences. Clin. Biochem. 19 (1986) 132-141
    • (1986) Clin. Biochem. , vol.19 , pp. 132-141
    • Okey, A.B.1    Roberts, E.A.2    Harper, P.A.3    Denison, M.S.4
  • 113
    • 0025277085 scopus 로고
    • Induction and developmental expression of cytochrome P450IA1 messenger RNA in rat and human tissues: Detection by the polymerase chain reaction
    • Omiecinski C.J., Redlich C.A., and Costa P. Induction and developmental expression of cytochrome P450IA1 messenger RNA in rat and human tissues: Detection by the polymerase chain reaction. Cancer Res. 50 (1990) 4315-4321
    • (1990) Cancer Res. , vol.50 , pp. 4315-4321
    • Omiecinski, C.J.1    Redlich, C.A.2    Costa, P.3
  • 114
    • 78651165715 scopus 로고
    • The carbon monoxide-binding pigment of liver microsomes
    • Omura T., and Sato R. The carbon monoxide-binding pigment of liver microsomes. J. Biol. Chem. 239 7 (1964) 2370-2378
    • (1964) J. Biol. Chem. , vol.239 , Issue.7 , pp. 2370-2378
    • Omura, T.1    Sato, R.2
  • 115
    • 0028942964 scopus 로고
    • The pharmacokinetics of teniloxazine in healthy subjects and patients with hepatic cirrhosis
    • Orlando R., Benvenuti C., Mazzo M., and Palatini P. The pharmacokinetics of teniloxazine in healthy subjects and patients with hepatic cirrhosis. Br. J. Clin. Pharmacol. 39 4 (1995) 445-448
    • (1995) Br. J. Clin. Pharmacol. , vol.39 , Issue.4 , pp. 445-448
    • Orlando, R.1    Benvenuti, C.2    Mazzo, M.3    Palatini, P.4
  • 116
    • 0026536336 scopus 로고
    • On the nature of nongenotoxic carcinogens. A unified theory including NGCs, co-carcinogens and promotors
    • Paolini M., Biagi G.L., Bauer C., and Cantelli-Forti G. On the nature of nongenotoxic carcinogens. A unified theory including NGCs, co-carcinogens and promotors. Mutat. Res. 281 4 (1992) 245-246
    • (1992) Mutat. Res. , vol.281 , Issue.4 , pp. 245-246
    • Paolini, M.1    Biagi, G.L.2    Bauer, C.3    Cantelli-Forti, G.4
  • 117
    • 0019832026 scopus 로고
    • Clinical implications of enzyme induction and enzyme inhibition
    • Park B.K., and Breckenridge A.M. Clinical implications of enzyme induction and enzyme inhibition. Clin. Pharmacokinet. 6 (1981) 1-24
    • (1981) Clin. Pharmacokinet. , vol.6 , pp. 1-24
    • Park, B.K.1    Breckenridge, A.M.2
  • 118
    • 0026095802 scopus 로고
    • The role of the cytochromes P450 in the detoxication and activation of drugs and other chemicals
    • Parke D.V., Ioannides C., and Lewis D.F.V. The role of the cytochromes P450 in the detoxication and activation of drugs and other chemicals. Can. J. Physiol. Pharmacol. 69 (1991) 537-549
    • (1991) Can. J. Physiol. Pharmacol. , vol.69 , pp. 537-549
    • Parke, D.V.1    Ioannides, C.2    Lewis, D.F.V.3
  • 120
    • 0025793209 scopus 로고
    • Omeprazole and the induction of human cytochrome P-450: A response to concerns about potential adverse effects
    • Parkinson A., and Hurwitz A. Omeprazole and the induction of human cytochrome P-450: A response to concerns about potential adverse effects. Gastroenterology 100 4 (1991) 1157-1164
    • (1991) Gastroenterology , vol.100 , Issue.4 , pp. 1157-1164
    • Parkinson, A.1    Hurwitz, A.2
  • 121
    • 0028864296 scopus 로고
    • Comparison of chloroguanide and mephenytoin for the in vivo assessment of genetically determined CYP2C19 activity in humans
    • Partovian C., Jacqz-Aigrain E., Keundjian A., Jaillon P., and Funck-Brentano C. Comparison of chloroguanide and mephenytoin for the in vivo assessment of genetically determined CYP2C19 activity in humans. Clin. Pharmacol. Ther. 58 3 (1995) 257-263
    • (1995) Clin. Pharmacol. Ther. , vol.58 , Issue.3 , pp. 257-263
    • Partovian, C.1    Jacqz-Aigrain, E.2    Keundjian, A.3    Jaillon, P.4    Funck-Brentano, C.5
  • 122
    • 0023184313 scopus 로고
    • Clinical implications of hepatic microsomal enzyme induction by antiepileptic drugs
    • Perucca E. Clinical implications of hepatic microsomal enzyme induction by antiepileptic drugs. Pharmacol. Ther. 33 (1987) 139-144
    • (1987) Pharmacol. Ther. , vol.33 , pp. 139-144
    • Perucca, E.1
  • 123
  • 125
    • 0025134337 scopus 로고
    • Cyclosporin A drug interactions. Screening for inducers and inhibitors of cytochrome P-450 (cyclosporin A oxidase) in primary cultures of human hepatocytes and in liver microsomes
    • Pichard L., Fabre I., Fabre G., Domergue J., Saint Aubert B., Mourad G., and Maurel P. Cyclosporin A drug interactions. Screening for inducers and inhibitors of cytochrome P-450 (cyclosporin A oxidase) in primary cultures of human hepatocytes and in liver microsomes. Drug Metab. Dispos. 18 5 (1990) 595-606
    • (1990) Drug Metab. Dispos. , vol.18 , Issue.5 , pp. 595-606
    • Pichard, L.1    Fabre, I.2    Fabre, G.3    Domergue, J.4    Saint Aubert, B.5    Mourad, G.6    Maurel, P.7
  • 126
    • 0019219257 scopus 로고
    • A rapid method for assaying the metabolism of 7-ethoxyresorufin by microsomal subcellular fractions
    • Pohl R., and Fouts J.R. A rapid method for assaying the metabolism of 7-ethoxyresorufin by microsomal subcellular fractions. Anal. Biochem. 107 (1980) 150-155
    • (1980) Anal. Biochem. , vol.107 , pp. 150-155
    • Pohl, R.1    Fouts, J.R.2
  • 127
    • 0020439501 scopus 로고
    • Induction of the drug-metabolizing enzymes (review)
    • Poland A. Induction of the drug-metabolizing enzymes (review). IARC Sci. Publ. 39 (1982) 351-364
    • (1982) IARC Sci. Publ. , vol.39 , pp. 351-364
    • Poland, A.1
  • 128
    • 0015152279 scopus 로고
    • The metabolism of aminopyrine in chick embryo hepatic cell culture: Effects of competitive substrates and carbon monoxide
    • Poland A., and Kappas A. The metabolism of aminopyrine in chick embryo hepatic cell culture: Effects of competitive substrates and carbon monoxide. Mol. Pharmacol. 7 6 (1971) 697-705
    • (1971) Mol. Pharmacol. , vol.7 , Issue.6 , pp. 697-705
    • Poland, A.1    Kappas, A.2
  • 129
    • 0019813219 scopus 로고
    • Changes in the metabolic profiles of R-and S-warfarin and R- and S-phenprocoumon as a probe to categorize the effect of inducing agents on microsomal hydroxylases
    • Porter W.R., Wheeler C., and Trager W.F. Changes in the metabolic profiles of R-and S-warfarin and R- and S-phenprocoumon as a probe to categorize the effect of inducing agents on microsomal hydroxylases. Biochem. Pharmacol. 30 22 (1981) 3099-3104
    • (1981) Biochem. Pharmacol. , vol.30 , Issue.22 , pp. 3099-3104
    • Porter, W.R.1    Wheeler, C.2    Trager, W.F.3
  • 130
    • 0017070851 scopus 로고
    • An improved assay for steroid glucuronyltransferase in rat liver microsomes
    • Rao G.S., Haueter G., Rao M.L., and Breuer H. An improved assay for steroid glucuronyltransferase in rat liver microsomes. Anal. Biochem. 74 (1976) 35-40
    • (1976) Anal. Biochem. , vol.74 , pp. 35-40
    • Rao, G.S.1    Haueter, G.2    Rao, M.L.3    Breuer, H.4
  • 131
    • 0023182895 scopus 로고
    • Induction and its influence on human cancer
    • Remmer H. Induction and its influence on human cancer. Pharmacol. Ther. 33 (1987) 89-94
    • (1987) Pharmacol. Ther. , vol.33 , pp. 89-94
    • Remmer, H.1
  • 132
    • 0028208696 scopus 로고
    • Enhancement of hepatocarcinogenesis and induction of specific cytochrome P450-dependent monooxygenase activities by the barbiturates allobarbital, aprobarbital, pentobarbital, secobarbital and 5-phenyl- and 5-ethylbarbituric acids
    • Rice J.M., Diwan B.A., Hu H., Ward J.M., Nims R.W., and Lubet R.A. Enhancement of hepatocarcinogenesis and induction of specific cytochrome P450-dependent monooxygenase activities by the barbiturates allobarbital, aprobarbital, pentobarbital, secobarbital and 5-phenyl- and 5-ethylbarbituric acids. Carcinogenesis (London) 15 2 (1994) 395-402
    • (1994) Carcinogenesis (London) , vol.15 , Issue.2 , pp. 395-402
    • Rice, J.M.1    Diwan, B.A.2    Hu, H.3    Ward, J.M.4    Nims, R.W.5    Lubet, R.A.6
  • 133
    • 0028114740 scopus 로고
    • Use of in vitro human metabolism studies in drug development. An industrial perspective
    • Rodrigues A.D. Use of in vitro human metabolism studies in drug development. An industrial perspective. Biochem. Pharmacol 48 12 (1994) 2147-2156
    • (1994) Biochem. Pharmacol , vol.48 , Issue.12 , pp. 2147-2156
    • Rodrigues, A.D.1
  • 134
    • 0023875216 scopus 로고
    • Determination of microsomal lauric acid hydroxylase activity by HPLC with flow-through radiochemical quantitation
    • Romano M.C., Straub K.M., Yodis Y.A.D., Eckardt R.D., and Newton J.F. Determination of microsomal lauric acid hydroxylase activity by HPLC with flow-through radiochemical quantitation. Anal. Biochem. 170 (1988) 83-93
    • (1988) Anal. Biochem. , vol.170 , pp. 83-93
    • Romano, M.C.1    Straub, K.M.2    Yodis, Y.A.D.3    Eckardt, R.D.4    Newton, J.F.5
  • 136
    • 0028051743 scopus 로고
    • Specific and dose-dependent enzyme induction by omeprazole in human beings
    • Rost K.L., Brösicke H., Heinemeyer G., and Roots I. Specific and dose-dependent enzyme induction by omeprazole in human beings. Hepatology 20 (1994) 1204-1212
    • (1994) Hepatology , vol.20 , pp. 1204-1212
    • Rost, K.L.1    Brösicke, H.2    Heinemeyer, G.3    Roots, I.4
  • 137
    • 0025139447 scopus 로고
    • Purification and characterization of hepatic microsomal cytochrome P-450
    • Ryan D.E., and Levin W. Purification and characterization of hepatic microsomal cytochrome P-450. Pharmacol. Ther. 45 (1990) 153-239
    • (1990) Pharmacol. Ther. , vol.45 , pp. 153-239
    • Ryan, D.E.1    Levin, W.2
  • 138
    • 0018405140 scopus 로고
    • Separation and characterization of highly purified forms of liver microsomal cytochrome P-450 from rats treated with polychlorinated biphenyls, phenobarbital, and 3-methylcholanthrene
    • Ryan D.E., Thomas P.E., Korzeniowski D., and Levin W. Separation and characterization of highly purified forms of liver microsomal cytochrome P-450 from rats treated with polychlorinated biphenyls, phenobarbital, and 3-methylcholanthrene. J. Biol. Chem. 254 (1979) 1365-1374
    • (1979) J. Biol. Chem. , vol.254 , pp. 1365-1374
    • Ryan, D.E.1    Thomas, P.E.2    Korzeniowski, D.3    Levin, W.4
  • 139
    • 0019161825 scopus 로고
    • Hepatic microsomal cytochrome P-450 form rats treated with isosafrole
    • Ryan D.E., Thomas P.E., and Levin W. Hepatic microsomal cytochrome P-450 form rats treated with isosafrole. J. Biol. Chem. 255 (1980) 7941-7955
    • (1980) J. Biol. Chem. , vol.255 , pp. 7941-7955
    • Ryan, D.E.1    Thomas, P.E.2    Levin, W.3
  • 140
    • 0027208730 scopus 로고
    • Urinary D-glucaric acid, a marker substance for microsomal enzyme induction. Methodological aspects, responses to alcohol and findings in workers exposed to toluene
    • Sandstad O., Osnes T., Skar V., and Osnes M. Urinary D-glucaric acid, a marker substance for microsomal enzyme induction. Methodological aspects, responses to alcohol and findings in workers exposed to toluene. Scand. J. Clin. Lab. Invest. 53 (1993) 327-333
    • (1993) Scand. J. Clin. Lab. Invest. , vol.53 , pp. 327-333
    • Sandstad, O.1    Osnes, T.2    Skar, V.3    Osnes, M.4
  • 142
    • 0018786980 scopus 로고
    • Phenol sulfotransferases
    • Sekura R.D., and Jakoby W.B. Phenol sulfotransferases. J. Biol. Chem. 254 (1979) 5658-5663
    • (1979) J. Biol. Chem. , vol.254 , pp. 5658-5663
    • Sekura, R.D.1    Jakoby, W.B.2
  • 144
    • 0028231149 scopus 로고
    • Mechanisms of non-genotoxic carcinogenesis
    • Shaw I.C., and Jones H.B. Mechanisms of non-genotoxic carcinogenesis. Trends Pharmacol. Sci. 15 (1994) 89-93
    • (1994) Trends Pharmacol. Sci. , vol.15 , pp. 89-93
    • Shaw, I.C.1    Jones, H.B.2
  • 145
    • 0028237729 scopus 로고
    • Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: Studies with liver microsomes of 30 Japanese and 30 Caucasians
    • Shimada T., Yamazaki H., Mimura M., Inui Y., and Guengerich F.P. Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: Studies with liver microsomes of 30 Japanese and 30 Caucasians. J. Pharmacol. Exp. Ther. 270 1 (1994) 414-423
    • (1994) J. Pharmacol. Exp. Ther. , vol.270 , Issue.1 , pp. 414-423
    • Shimada, T.1    Yamazaki, H.2    Mimura, M.3    Inui, Y.4    Guengerich, F.P.5
  • 147
    • 0029932214 scopus 로고    scopus 로고
    • Time for a consistent approach to preparing and culturing hepatocytes
    • Skett P., and Bayliss M. Time for a consistent approach to preparing and culturing hepatocytes. Xenobiotica 26 1 (1996) 1-7
    • (1996) Xenobiotica , vol.26 , Issue.1 , pp. 1-7
    • Skett, P.1    Bayliss, M.2
  • 148
    • 0018581336 scopus 로고
    • Classes of hepatic microsomal mixed function oxidase inducers
    • Snyder R., and Remmer H. Classes of hepatic microsomal mixed function oxidase inducers. Pharmacol. Ther. 7 (1979) 203-244
    • (1979) Pharmacol. Ther. , vol.7 , pp. 203-244
    • Snyder, R.1    Remmer, H.2
  • 150
    • 0026569805 scopus 로고
    • Cytochromes P-450 in rats: Structures, functions, properties and relevant human forms (review)
    • Soucek P., and Gut I. Cytochromes P-450 in rats: Structures, functions, properties and relevant human forms (review). Xenobiotica 22 1 (1992) 83-103
    • (1992) Xenobiotica , vol.22 , Issue.1 , pp. 83-103
    • Soucek, P.1    Gut, I.2
  • 151
    • 0026703155 scopus 로고
    • Cytochrome P-450 induction in human lung tumor-derived cell lines. Characterization and effect of inflammatory mediators
    • Stanley L.A., Carmichael J., and Wolf C.R. Cytochrome P-450 induction in human lung tumor-derived cell lines. Characterization and effect of inflammatory mediators. Eur. J. Biochem. 208 (1992) 521-529
    • (1992) Eur. J. Biochem. , vol.208 , pp. 521-529
    • Stanley, L.A.1    Carmichael, J.2    Wolf, C.R.3
  • 152
    • 0028953763 scopus 로고
    • Induction of cytochrome P4501A1 by aryl hydrocarbon receptor agonists in porcine aorta endothelial cells in culture and cytochrome P4501A1 activity in intact cells
    • Stegeman J.J., Hahn M.E., Weisbrod R., Woodin B.R., Joy J.S., Najibi S., and Cohen R.A. Induction of cytochrome P4501A1 by aryl hydrocarbon receptor agonists in porcine aorta endothelial cells in culture and cytochrome P4501A1 activity in intact cells. Mol. Pharmacol. 47 (1995) 296-306
    • (1995) Mol. Pharmacol. , vol.47 , pp. 296-306
    • Stegeman, J.J.1    Hahn, M.E.2    Weisbrod, R.3    Woodin, B.R.4    Joy, J.S.5    Najibi, S.6    Cohen, R.A.7
  • 153
    • 0025937736 scopus 로고
    • A novel rat hepatic clofibrate-inducible cytochrome P450 that is not a lauric acid hydroxylase
    • Swinney D.C., Webb A.S., and Freedman R. A novel rat hepatic clofibrate-inducible cytochrome P450 that is not a lauric acid hydroxylase. Biochem. Pharmacol. 42 12 (1991) 2341-2349
    • (1991) Biochem. Pharmacol. , vol.42 , Issue.12 , pp. 2341-2349
    • Swinney, D.C.1    Webb, A.S.2    Freedman, R.3
  • 154
    • 0029151384 scopus 로고
    • Ancillary approaches to toxicokinetic evaluations
    • Takacs A.R. Ancillary approaches to toxicokinetic evaluations. Toxicol. Pathol. 23 2 (1995) 179-186
    • (1995) Toxicol. Pathol. , vol.23 , Issue.2 , pp. 179-186
    • Takacs, A.R.1
  • 157
    • 0021339284 scopus 로고
    • Characterization of nine monoclonal antibodies against rat hepatic cytochrome P-450c
    • Thomas P.E., Reik L.M., Ryan D.E., and Levin W. Characterization of nine monoclonal antibodies against rat hepatic cytochrome P-450c. J. Biol. Chem. 259 (1984) 3890-3899
    • (1984) J. Biol. Chem. , vol.259 , pp. 3890-3899
    • Thomas, P.E.1    Reik, L.M.2    Ryan, D.E.3    Levin, W.4
  • 158
    • 0020422902 scopus 로고
    • Effect of microsomal enzyme inducers on the soluble enzymes of hepatic phase II biotransformation
    • Thompson T.N., Watkins J.B., Gregus Z., and Klaassen C.D. Effect of microsomal enzyme inducers on the soluble enzymes of hepatic phase II biotransformation. Toxicol. Appl. Pharmacol. 66 (1982) 400-408
    • (1982) Toxicol. Appl. Pharmacol. , vol.66 , pp. 400-408
    • Thompson, T.N.1    Watkins, J.B.2    Gregus, Z.3    Klaassen, C.D.4
  • 159
    • 77956774753 scopus 로고    scopus 로고
    • T.N. Thompson J.G. Geary S.E. Unwin J.J. Dunn P.W. Brown D.R. Osborne K.K. Hwang 1990. Evaluation of ML 1012 as an hepatic enzyme inducer in rats, dogs, and monkeys. Abstr., North Am. International Society for the Study of Xenobiotics (ISSX) Meet., 3rd, San Diego, Ca, 1990, Abstr. No. 185
    • T.N. Thompson J.G. Geary S.E. Unwin J.J. Dunn P.W. Brown D.R. Osborne K.K. Hwang 1990). Evaluation of ML 1012 as an hepatic enzyme inducer in rats, dogs, and monkeys. Abstr., North Am. International Society for the Study of Xenobiotics (ISSX) Meet., 3rd, San Diego, Ca, 1990, Abstr. No. 185
  • 161
    • 0009482260 scopus 로고
    • Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications
    • Towbin H., Staehelin T., and Gordon J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications. Proc. Natl. Acad. Sci. U. S. A. 76 (1979) 4350-4354
    • (1979) Proc. Natl. Acad. Sci. U. S. A. , vol.76 , pp. 4350-4354
    • Towbin, H.1    Staehelin, T.2    Gordon, J.3
  • 162
    • 77956760629 scopus 로고    scopus 로고
    • J.E. Turner J.H. Leighton M. Cunningham S.L. Cox L.B. Hogan M.J. O'Sullivan 1994. The development of enzyme linked immunoadsorbent assays (ELISA's) for cytochrome P450's. Abstr. North Am. ISSX Meet., 6th, Raleigh, NC, 1994, Abstr. No. 180
    • J.E. Turner J.H. Leighton M. Cunningham S.L. Cox L.B. Hogan M.J. O'Sullivan 1994). The development of enzyme linked immunoadsorbent assays (ELISA's) for cytochrome P450's. Abstr. North Am. ISSX Meet., 6th, Raleigh, NC, 1994, Abstr. No. 180
  • 164
    • 0014269889 scopus 로고
    • Determination of bilirubin glucuronide and assay of glucuronyltransferase with bilirubin as acceptor
    • VanRoy F.P., and Heirwegh K.P.M. Determination of bilirubin glucuronide and assay of glucuronyltransferase with bilirubin as acceptor. Biochem. J. 107 (1968) 507-518
    • (1968) Biochem. J. , vol.107 , pp. 507-518
    • VanRoy, F.P.1    Heirwegh, K.P.M.2
  • 165
    • 0026531077 scopus 로고
    • Pharmacokinetic drug interactions with rifampicin
    • Venkatesan K. Pharmacokinetic drug interactions with rifampicin. Clin. Pharmacokinet. 22 1 (1992) 47-65
    • (1992) Clin. Pharmacokinet. , vol.22 , Issue.1 , pp. 47-65
    • Venkatesan, K.1
  • 166
    • 0021363165 scopus 로고
    • Induction of cytosolic and microsomal epoxide hydrolases by the hypolipidaemic compound nafenopin in the mouse liver
    • Waechter F., Bieri F., Staubli W., and Bentley P. Induction of cytosolic and microsomal epoxide hydrolases by the hypolipidaemic compound nafenopin in the mouse liver. Biochem. Pharmacol. 33 1 (1984) 31-34
    • (1984) Biochem. Pharmacol. , vol.33 , Issue.1 , pp. 31-34
    • Waechter, F.1    Bieri, F.2    Staubli, W.3    Bentley, P.4
  • 167
    • 0023791757 scopus 로고
    • Organ distribution of epoxide hydrolases in cytosolic and microsomal fractions of normal and nafenopin-treated male DBA/2 mice
    • Waechter F., Bentley P., Bieri F., Muakkassah-Kelly S., Staubli W., and Villermain M. Organ distribution of epoxide hydrolases in cytosolic and microsomal fractions of normal and nafenopin-treated male DBA/2 mice. Biochem. Pharmacol. 37 20 (1988) 3897-3903
    • (1988) Biochem. Pharmacol. , vol.37 , Issue.20 , pp. 3897-3903
    • Waechter, F.1    Bentley, P.2    Bieri, F.3    Muakkassah-Kelly, S.4    Staubli, W.5    Villermain, M.6
  • 168
    • 0020044727 scopus 로고
    • Effect of inducers and inhibitors of glucuronidation on the biliary excretion and choleretic action of valproic acid in the rat
    • Watkins J.B., and Klaassen C.D. Effect of inducers and inhibitors of glucuronidation on the biliary excretion and choleretic action of valproic acid in the rat. J. Pharmacol. Exp. Ther. 220 (1982) 305-310
    • (1982) J. Pharmacol. Exp. Ther. , vol.220 , pp. 305-310
    • Watkins, J.B.1    Klaassen, C.D.2
  • 169
    • 0019943588 scopus 로고
    • Induction studies on the functional heterogeneity of rat liver UDP-glucuronosyltransferases
    • Watkins J.B., Gregus Z., Thompson T.N., and Klaassen C.D. Induction studies on the functional heterogeneity of rat liver UDP-glucuronosyltransferases. Toxicol. Appl. Pharmacol. 64 (1982) 439-446
    • (1982) Toxicol. Appl. Pharmacol. , vol.64 , pp. 439-446
    • Watkins, J.B.1    Gregus, Z.2    Thompson, T.N.3    Klaassen, C.D.4
  • 170
    • 0025688972 scopus 로고
    • Role of cytochromes P450 in drug metabolism and hepatoxicity
    • Watkins P.B. Role of cytochromes P450 in drug metabolism and hepatoxicity. Semin. Liver Dis. 10 4 (1990) 235-250
    • (1990) Semin. Liver Dis. , vol.10 , Issue.4 , pp. 235-250
    • Watkins, P.B.1
  • 173
    • 0026512675 scopus 로고
    • Phenobarbital induction of cytochrome P-450 gene expression
    • Waxman D.J., and Azaroff L. Phenobarbital induction of cytochrome P-450 gene expression. Biochem. J. 281 (1992) 577-592
    • (1992) Biochem. J. , vol.281 , pp. 577-592
    • Waxman, D.J.1    Azaroff, L.2
  • 174
    • 0000978314 scopus 로고
    • N-acetyltransferase (mammalian liver)
    • Tabor H., and Tabor C.W. (Eds), Academic Press, New York
    • Weber W.W. N-acetyltransferase (mammalian liver). In: Tabor H., and Tabor C.W. (Eds). "Methods in Enzymology" 17B (1971), Academic Press, New York 805-811
    • (1971) "Methods in Enzymology" , vol.17 B , pp. 805-811
    • Weber, W.W.1
  • 175
    • 0022975512 scopus 로고
    • Rat liver NAD(P)H: quinone reductase. Construction of a quinone reductase cDNA clone and regulation of quinone reductase mRNA by 3-methylcholanthrene and in persistent hepatocyte nodules induced by chemical carcinogens
    • Williams J.B., Lu A.Y., Cameron R.G., and Pickett C.B. Rat liver NAD(P)H: quinone reductase. Construction of a quinone reductase cDNA clone and regulation of quinone reductase mRNA by 3-methylcholanthrene and in persistent hepatocyte nodules induced by chemical carcinogens. J. Biol. Chem. 261 12 (1986) 5524-5528
    • (1986) J. Biol. Chem. , vol.261 , Issue.12 , pp. 5524-5528
    • Williams, J.B.1    Lu, A.Y.2    Cameron, R.G.3    Pickett, C.B.4
  • 176
    • 0014664072 scopus 로고
    • Studies on the activation in vitro of glucuronyltransferase
    • Winsnes A. Studies on the activation in vitro of glucuronyltransferase. Biochim. Biophys. Acta 191 (1969) 279-291
    • (1969) Biochim. Biophys. Acta , vol.191 , pp. 279-291
    • Winsnes, A.1
  • 177
    • 0017837214 scopus 로고
    • Chloramphenicol glucuronyltransferase: Assay, ontogeny, and inducibility
    • Young W.S., and Lietman P.S. Chloramphenicol glucuronyltransferase: Assay, ontogeny, and inducibility. J. Pharmacol. Exp. Ther. 204 (1978) 203-211
    • (1978) J. Pharmacol. Exp. Ther. , vol.204 , pp. 203-211
    • Young, W.S.1    Lietman, P.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.