-
1
-
-
0001413057
-
Evidence for the function of D-glucaric acid as an indicator for drug induced enhanced metabolism through the glucuronic acid pathway in man
-
Aarts E.M. Evidence for the function of D-glucaric acid as an indicator for drug induced enhanced metabolism through the glucuronic acid pathway in man. Biochem. Pharmacol. 14 (1964) 359-363
-
(1964)
Biochem. Pharmacol.
, vol.14
, pp. 359-363
-
-
Aarts, E.M.1
-
2
-
-
0015238212
-
D-glucaric-acid excretion as a test for hepatic enzyme induction
-
Aarts E.M. D-glucaric-acid excretion as a test for hepatic enzyme induction. Lancet 1 704 (1971) 859
-
(1971)
Lancet
, vol.1
, Issue.704
, pp. 859
-
-
Aarts, E.M.1
-
3
-
-
0014168787
-
Enzymatic synthesis of steroid sulphates. III. Isolation and properties of estrogen sulphotransferase of bovine adrenal glands
-
Adams J.B., and Poulos A. Enzymatic synthesis of steroid sulphates. III. Isolation and properties of estrogen sulphotransferase of bovine adrenal glands. Biochim. Biophys. Acta 146 (1967) 493-508
-
(1967)
Biochim. Biophys. Acta
, vol.146
, pp. 493-508
-
-
Adams, J.B.1
Poulos, A.2
-
4
-
-
0028047394
-
Abnormal bone mineral metabolism after long-term anticonvulsant treatment
-
Alderman C.P., and Hill C.L. Abnormal bone mineral metabolism after long-term anticonvulsant treatment. Ann. Pharmacother. 28 (1994) 47-48
-
(1994)
Ann. Pharmacother.
, vol.28
, pp. 47-48
-
-
Alderman, C.P.1
Hill, C.L.2
-
5
-
-
0024584510
-
Purification of two isozymes of rat liver microsomal cytochrome P450 with testosterone 7;ga-hydroxylase activity
-
Arlotto M.P., Greenway D.J., and Parkinson A. Purification of two isozymes of rat liver microsomal cytochrome P450 with testosterone 7;ga-hydroxylase activity. Arch. Biochem. Biophys. 270 (1989) 441-457
-
(1989)
Arch. Biochem. Biophys.
, vol.270
, pp. 441-457
-
-
Arlotto, M.P.1
Greenway, D.J.2
Parkinson, A.3
-
6
-
-
0027523486
-
Use of single sample clearance estimates of cytochrome P450 substrates to characterize human hepatic CYP status in vivo
-
Bachmann K.A., and Jauregui L. Use of single sample clearance estimates of cytochrome P450 substrates to characterize human hepatic CYP status in vivo. Xenobiotica 23 3 (1993) 307-315
-
(1993)
Xenobiotica
, vol.23
, Issue.3
, pp. 307-315
-
-
Bachmann, K.A.1
Jauregui, L.2
-
7
-
-
0030068752
-
Rifampin drastically reduces plasma concentrations and effects of oral midazolam
-
Backman J.T., Olkkola K.T., and Neuvonen P.J. Rifampin drastically reduces plasma concentrations and effects of oral midazolam. Clin. Pharmacol. Ther. 59 (1996) 7-13
-
(1996)
Clin. Pharmacol. Ther.
, vol.59
, pp. 7-13
-
-
Backman, J.T.1
Olkkola, K.T.2
Neuvonen, P.J.3
-
8
-
-
0020856024
-
Clinical utility of breath tests for the assessment of hepatic function
-
Baker A.L., Kotake A.N., and Schoeller D.A. Clinical utility of breath tests for the assessment of hepatic function. Semin. Liver Dis. 3 4 (1983) 318-329
-
(1983)
Semin. Liver Dis.
, vol.3
, Issue.4
, pp. 318-329
-
-
Baker, A.L.1
Kotake, A.N.2
Schoeller, D.A.3
-
9
-
-
0029018767
-
The hydroxylation of omeprazole correlates with S-mephenytoin metabolism: A population study
-
Balian J.D., Sukhova N., Harris J.W., Hewett J., Pickle L., Goldstein J.A., Woosley R.L., and Flockhart D.A. The hydroxylation of omeprazole correlates with S-mephenytoin metabolism: A population study. Clin. Pharmacol. Ther. 56 6 (1995) 662-669
-
(1995)
Clin. Pharmacol. Ther.
, vol.56
, Issue.6
, pp. 662-669
-
-
Balian, J.D.1
Sukhova, N.2
Harris, J.W.3
Hewett, J.4
Pickle, L.5
Goldstein, J.A.6
Woosley, R.L.7
Flockhart, D.A.8
-
10
-
-
0026680310
-
Divergent effects of different enzyme-inducing agents on endogenous and exogenous testosterone
-
Bammel A., van der Mee K., Ohnhaus E.E., and Kirch W. Divergent effects of different enzyme-inducing agents on endogenous and exogenous testosterone. Eur. J. Clin. Pharmacol. 42 (1992) 641-644
-
(1992)
Eur. J. Clin. Pharmacol.
, vol.42
, pp. 641-644
-
-
Bammel, A.1
van der Mee, K.2
Ohnhaus, E.E.3
Kirch, W.4
-
11
-
-
0025035723
-
Enzyme induction and inhibition
-
Barry M., and Freely J. Enzyme induction and inhibition. Pharmacol. Ther. 48 (1990) 71-94
-
(1990)
Pharmacol. Ther.
, vol.48
, pp. 71-94
-
-
Barry, M.1
Freely, J.2
-
12
-
-
0028095346
-
Reduction of thyroid hormone levels and alteration of thyroid function by four representative UDP-glucuronosyltransferase inducers in rats
-
Barter R.A., and Klaassen C.D. Reduction of thyroid hormone levels and alteration of thyroid function by four representative UDP-glucuronosyltransferase inducers in rats. Toxicol. Appl. Pharmacol. 128 (1994) 9-17
-
(1994)
Toxicol. Appl. Pharmacol.
, vol.128
, pp. 9-17
-
-
Barter, R.A.1
Klaassen, C.D.2
-
14
-
-
0028567499
-
Induction and autoinduction properties of rifamycin derivatives: A review of animal and human studies
-
Benedetti M.S., and Dostert P. Induction and autoinduction properties of rifamycin derivatives: A review of animal and human studies. Environ. Health Perspect. 102 9 (1994) 101-105
-
(1994)
Environ. Health Perspect.
, vol.102
, Issue.9
, pp. 101-105
-
-
Benedetti, M.S.1
Dostert, P.2
-
16
-
-
0029077901
-
Brain mitochondrial cytochromes P450: Xenobiotic metabolism, presence of multiple forms and their selective inducibility
-
Bhagwat S.V., Boyd M.R., and Ravindranath V. Brain mitochondrial cytochromes P450: Xenobiotic metabolism, presence of multiple forms and their selective inducibility. Arch. Biochem. Biophys. 320 1 (1995) 73-83
-
(1995)
Arch. Biochem. Biophys.
, vol.320
, Issue.1
, pp. 73-83
-
-
Bhagwat, S.V.1
Boyd, M.R.2
Ravindranath, V.3
-
17
-
-
0025992813
-
A simple non-invasive procedure for the investigation of cytochrome P-450 IIIA dependent enzymes in humans
-
Bienvenu T., Rey E., Pons G., D'Athis P., and Olive G. A simple non-invasive procedure for the investigation of cytochrome P-450 IIIA dependent enzymes in humans. Int. J. Clin. Pharmacol. Ther. Toxicol. 29 (1991) 441-445
-
(1991)
Int. J. Clin. Pharmacol. Ther. Toxicol.
, vol.29
, pp. 441-445
-
-
Bienvenu, T.1
Rey, E.2
Pons, G.3
D'Athis, P.4
Olive, G.5
-
18
-
-
0015926539
-
Effects of phenobarbital and 3-methylcholanthrene on substrate specificity of rat liver microsomal UDP-glucuronyltransferase
-
Bock K.W., Frohling W., Remmer H., and Rexer B. Effects of phenobarbital and 3-methylcholanthrene on substrate specificity of rat liver microsomal UDP-glucuronyltransferase. Biochim. Biophys. Acta 327 (1973) 46-56
-
(1973)
Biochim. Biophys. Acta
, vol.327
, pp. 46-56
-
-
Bock, K.W.1
Frohling, W.2
Remmer, H.3
Rexer, B.4
-
19
-
-
0018145527
-
Determination of microsomal UDP-glucuronyl-transferase in needle-biopsy specimens of human liver
-
Bock K.W., Brunner G., Hoensch H., Huber E., and Josting D. Determination of microsomal UDP-glucuronyl-transferase in needle-biopsy specimens of human liver. Eur. J. Clin. Pharmacol. 14 (1978) 367-373
-
(1978)
Eur. J. Clin. Pharmacol.
, vol.14
, pp. 367-373
-
-
Bock, K.W.1
Brunner, G.2
Hoensch, H.3
Huber, E.4
Josting, D.5
-
20
-
-
0025602894
-
Induction of drug-metabolizing enzymes by xenobiotics
-
Bock K.W., Lipp H.P., and Bock-Hennig B.S. Induction of drug-metabolizing enzymes by xenobiotics. Xenobiotica 20 (1990) 1101-1111
-
(1990)
Xenobiotica
, vol.20
, pp. 1101-1111
-
-
Bock, K.W.1
Lipp, H.P.2
Bock-Hennig, B.S.3
-
21
-
-
0028985925
-
The kinetics of the auto-induction of ifosfamide metabolism during continuous infusion
-
Boddy A.V., Cole M., Pearson A.D.J., and Idle J.R. The kinetics of the auto-induction of ifosfamide metabolism during continuous infusion. Cancer Chemother. Pharmacol. 36 (1995) 53-60
-
(1995)
Cancer Chemother. Pharmacol.
, vol.36
, pp. 53-60
-
-
Boddy, A.V.1
Cole, M.2
Pearson, A.D.J.3
Idle, J.R.4
-
22
-
-
0027074986
-
Anti-liver microsomes autoantibodies and dihydralazine-induced hepatitis: Specificity of autoantibodies and inductive capacity of the drug
-
Bourdi M., Gautier J.C., Mircheva J., Larrey D., Guillouzo A., Andre C., Belloc C., and Beaune P.H. Anti-liver microsomes autoantibodies and dihydralazine-induced hepatitis: Specificity of autoantibodies and inductive capacity of the drug. Mol. Pharmacol. 42 (1992) 280-285
-
(1992)
Mol. Pharmacol.
, vol.42
, pp. 280-285
-
-
Bourdi, M.1
Gautier, J.C.2
Mircheva, J.3
Larrey, D.4
Guillouzo, A.5
Andre, C.6
Belloc, C.7
Beaune, P.H.8
-
23
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72 (1976) 248-254
-
(1976)
Anal. Biochem.
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
24
-
-
0023215959
-
Enzyme induction in humans-clinical aspects-an overview
-
Breckenridge A. Enzyme induction in humans-clinical aspects-an overview. Pharmacol. Ther. 33 (1987) 95-99
-
(1987)
Pharmacol. Ther.
, vol.33
, pp. 95-99
-
-
Breckenridge, A.1
-
25
-
-
0021276491
-
Induction of cytochrome P450 by xenobiotics
-
Bresnick E., Foldes R., and Hines R.N. Induction of cytochrome P450 by xenobiotics. Pharmacol. Rev. 36 2 (1984) 43S-51S
-
(1984)
Pharmacol. Rev.
, vol.36
, Issue.2
-
-
Bresnick, E.1
Foldes, R.2
Hines, R.N.3
-
26
-
-
0028095629
-
Assessment of liver metabolic function-clinical implications
-
Brockmöller J., and Roots I. Assessment of liver metabolic function-clinical implications. Clin. Pharmacokinet. 27 3 (1994) 216-248
-
(1994)
Clin. Pharmacokinet.
, vol.27
, Issue.3
, pp. 216-248
-
-
Brockmöller, J.1
Roots, I.2
-
27
-
-
0028558737
-
Induction of cytochrome P4501A by smoking or omeprazole in comparison with UDP-glucuronosyltransferase in biopsies of human duodenal mucosa
-
Buchthal J., Grund K.E., Buchmann A., Schrenk D., Beaune P., and Bock K.W. Induction of cytochrome P4501A by smoking or omeprazole in comparison with UDP-glucuronosyltransferase in biopsies of human duodenal mucosa. Eur. J. Clin. Pharmacol. 47 (1995) 431-435
-
(1995)
Eur. J. Clin. Pharmacol.
, vol.47
, pp. 431-435
-
-
Buchthal, J.1
Grund, K.E.2
Buchmann, A.3
Schrenk, D.4
Beaune, P.5
Bock, K.W.6
-
28
-
-
0029031411
-
Induction of liver microsomal cytochrome P450 in cynomolgus monkeys
-
Bullock P., Pearce R., Draper A., Podval J., Bracken W., Veltman J., Thomas P., and Parkinson A. Induction of liver microsomal cytochrome P450 in cynomolgus monkeys. Drug Metab. Dispos. 23 7 (1995) 736-748
-
(1995)
Drug Metab. Dispos.
, vol.23
, Issue.7
, pp. 736-748
-
-
Bullock, P.1
Pearce, R.2
Draper, A.3
Podval, J.4
Bracken, W.5
Veltman, J.6
Thomas, P.7
Parkinson, A.8
-
29
-
-
0016333916
-
Ethoxyresorufin: Direct fluorometric assay of a microsomal O-dealkylation which is preferentially inducible by 3-methylcholanthrene
-
Burke M.D., and Mayer R.T. Ethoxyresorufin: Direct fluorometric assay of a microsomal O-dealkylation which is preferentially inducible by 3-methylcholanthrene. Drug Metab. Dispos. 2 (1974) 583-588
-
(1974)
Drug Metab. Dispos.
, vol.2
, pp. 583-588
-
-
Burke, M.D.1
Mayer, R.T.2
-
30
-
-
0028106482
-
Cytochrome P450 specificities of alkoxyresorufin o-dealkylation in human and rat liver
-
Burke M.D., Thompson S., Weaver R.J., Wolf C.R., and Mayer R.T. Cytochrome P450 specificities of alkoxyresorufin o-dealkylation in human and rat liver. Biochem. Pharmacol. 48 5 (1994) 923-936
-
(1994)
Biochem. Pharmacol.
, vol.48
, Issue.5
, pp. 923-936
-
-
Burke, M.D.1
Thompson, S.2
Weaver, R.J.3
Wolf, C.R.4
Mayer, R.T.5
-
31
-
-
0020787408
-
A sensitive and specific stable isotope assy for warfarin and its metabolites
-
Bush E.D., Low L.K., and Trager W.F. A sensitive and specific stable isotope assy for warfarin and its metabolites. Biomed. Mass Spectrom. 10 7 (1983) 395-398
-
(1983)
Biomed. Mass Spectrom.
, vol.10
, Issue.7
, pp. 395-398
-
-
Bush, E.D.1
Low, L.K.2
Trager, W.F.3
-
32
-
-
0018824051
-
Glucuronidation of digitalis glycosides by rat liver microsomes: Stimulation by spironolactone and pregnenolone-16;ga-carbonitrile
-
Castle M.C. Glucuronidation of digitalis glycosides by rat liver microsomes: Stimulation by spironolactone and pregnenolone-16;ga-carbonitrile. Biochem. Pharmacol. 29 (1980) 1497-1502
-
(1980)
Biochem. Pharmacol.
, vol.29
, pp. 1497-1502
-
-
Castle, M.C.1
-
33
-
-
0017594533
-
Enzymatic sulfation of bile salts. Partial purification and characterization of an enzyme from rat liver that catalyzes the sulfation of bile salts
-
Chen L.J., Bolt R.J., and Admirand W.H. Enzymatic sulfation of bile salts. Partial purification and characterization of an enzyme from rat liver that catalyzes the sulfation of bile salts. Biochim. Biophys. Acta 480 (1977) 219-227
-
(1977)
Biochim. Biophys. Acta
, vol.480
, pp. 219-227
-
-
Chen, L.J.1
Bolt, R.J.2
Admirand, W.H.3
-
34
-
-
0014125542
-
Pharmacological implications of microsomal enzyme induction
-
Conney A.H. Pharmacological implications of microsomal enzyme induction. Pharmacol. Rev. 19 3 (1967) 317-366
-
(1967)
Pharmacol. Rev.
, vol.19
, Issue.3
, pp. 317-366
-
-
Conney, A.H.1
-
35
-
-
0025368026
-
Omeprazole is an aryl hydrocarbon-like inducer of human hepatic cytochrome P450
-
Diaz D., Fabre I., Daujat M., Saint Aubert B., Bories P., Michel H., and Maurel P. Omeprazole is an aryl hydrocarbon-like inducer of human hepatic cytochrome P450. Gastroenterology 99 (1990) 737-747
-
(1990)
Gastroenterology
, vol.99
, pp. 737-747
-
-
Diaz, D.1
Fabre, I.2
Daujat, M.3
Saint Aubert, B.4
Bories, P.5
Michel, H.6
Maurel, P.7
-
36
-
-
0029024968
-
Relative potencies of induction of hepatic drug-metabolizing enzyme genes by individual PCB congeners
-
Dragnev K.H., Nims R.W., Fox S.D., Lindahl R., and Lubet R.A. Relative potencies of induction of hepatic drug-metabolizing enzyme genes by individual PCB congeners. Toxicol. Appl. Pharmacol. 132 2 (1995) 334-342
-
(1995)
Toxicol. Appl. Pharmacol.
, vol.132
, Issue.2
, pp. 334-342
-
-
Dragnev, K.H.1
Nims, R.W.2
Fox, S.D.3
Lindahl, R.4
Lubet, R.A.5
-
37
-
-
0023722925
-
Differential gene expression in response to 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD). Noncoordinate regulation of a TCDD-induced aldehyde dehydrogenase and cytochrome P-450c in the rat
-
Dunn T.J., Lindahl R., and Pitot H.C. Differential gene expression in response to 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD). Noncoordinate regulation of a TCDD-induced aldehyde dehydrogenase and cytochrome P-450c in the rat. J. Biol. Chem. 263 22 (1988) 10878-10886
-
(1988)
J. Biol. Chem.
, vol.263
, Issue.22
, pp. 10878-10886
-
-
Dunn, T.J.1
Lindahl, R.2
Pitot, H.C.3
-
38
-
-
0022968251
-
Induction of mixed function oxidase activity in man by rifapentine (MDL 473), a long-acting rifamycin derivative
-
Durand D., Hampden C., Boobis A.R., Park B.K., and Davies D.S. Induction of mixed function oxidase activity in man by rifapentine (MDL 473), a long-acting rifamycin derivative. Br. J. Clin. Pharmacol. 21 (1986) 1-7
-
(1986)
Br. J. Clin. Pharmacol.
, vol.21
, pp. 1-7
-
-
Durand, D.1
Hampden, C.2
Boobis, A.R.3
Park, B.K.4
Davies, D.S.5
-
39
-
-
0024559081
-
Reduction of 7-alkoxyresorufins by NADPH-cytochrome P450 reductase and its differential effects on their O-dealkylation by rat liver microsomal cytochrome P450
-
Dutton D.R., and Parkinson A. Reduction of 7-alkoxyresorufins by NADPH-cytochrome P450 reductase and its differential effects on their O-dealkylation by rat liver microsomal cytochrome P450. Arch. Biochem. Biophys. 268 (1989) 617-629
-
(1989)
Arch. Biochem. Biophys.
, vol.268
, pp. 617-629
-
-
Dutton, D.R.1
Parkinson, A.2
-
40
-
-
0029683112
-
Antipyrine as a probe for human oxidative drug metabolism: Identification of the cytochrome P450 enzymes catalyzing 4-hydroxyantipyrine, 3-hydroxymethylantipyrine, and norantipyrine formation
-
Engel G., Hofmann U., Heidemann H., Cosme J., and Eichelbaum M. Antipyrine as a probe for human oxidative drug metabolism: Identification of the cytochrome P450 enzymes catalyzing 4-hydroxyantipyrine, 3-hydroxymethylantipyrine, and norantipyrine formation. Clin. Pharmacol. Ther. 59 (1996) 613-623
-
(1996)
Clin. Pharmacol. Ther.
, vol.59
, pp. 613-623
-
-
Engel, G.1
Hofmann, U.2
Heidemann, H.3
Cosme, J.4
Eichelbaum, M.5
-
41
-
-
0025316892
-
Human cytochrome P450 Isoforms-their genetic heterogeneity and induction by omeprazole
-
Farrell G.C., and Murray M. Human cytochrome P450 Isoforms-their genetic heterogeneity and induction by omeprazole. Gastroenterology 99 (1990) 885-889
-
(1990)
Gastroenterology
, vol.99
, pp. 885-889
-
-
Farrell, G.C.1
Murray, M.2
-
42
-
-
0025986720
-
Oral contraceptive drug interactions: Important considerations (see comments) (review)
-
Fazio A. Oral contraceptive drug interactions: Important considerations (see comments) (review). South. Med. J. 84 8 (1991) 997-1002
-
(1991)
South. Med. J.
, vol.84
, Issue.8
, pp. 997-1002
-
-
Fazio, A.1
-
43
-
-
0028937507
-
Phenytoin causes a rapid increase in 6;gb-hydroxycortisol urinary excretion in humans-a putative measure of CYP3A induction
-
Fleishaker J.C., Pearson L.K., and Peters G.R. Phenytoin causes a rapid increase in 6;gb-hydroxycortisol urinary excretion in humans-a putative measure of CYP3A induction. J. Pharm. Sci. 84 3 (1995) 292-294
-
(1995)
J. Pharm. Sci.
, vol.84
, Issue.3
, pp. 292-294
-
-
Fleishaker, J.C.1
Pearson, L.K.2
Peters, G.R.3
-
44
-
-
0028942623
-
Microsomal enzyme inducers raise plasma high-density lipoprotein cholesterol levels in healthy control subjects but not in patients with primary hypoalphalipoproteinemia
-
Franceschini G., D'Werba J.P., Acquarica A.L., Gianfranceshi G., Michelagnoli S., and Sirtori C.R. Microsomal enzyme inducers raise plasma high-density lipoprotein cholesterol levels in healthy control subjects but not in patients with primary hypoalphalipoproteinemia. Clin. Pharmacol. Ther. 57 (1995) 434-440
-
(1995)
Clin. Pharmacol. Ther.
, vol.57
, pp. 434-440
-
-
Franceschini, G.1
D'Werba, J.P.2
Acquarica, A.L.3
Gianfranceshi, G.4
Michelagnoli, S.5
Sirtori, C.R.6
-
45
-
-
0026584261
-
Differentiation of cytochrome P-450 inducers on the basis of 7-alkoxycoumarin O-dealkylase activities
-
Fry J.R., Garle M.J., and Lal K. Differentiation of cytochrome P-450 inducers on the basis of 7-alkoxycoumarin O-dealkylase activities. Xenobiotica 22 2 (1992) 211-215
-
(1992)
Xenobiotica
, vol.22
, Issue.2
, pp. 211-215
-
-
Fry, J.R.1
Garle, M.J.2
Lal, K.3
-
46
-
-
0024427759
-
The increase in urinary excretion of 6;gb-hydroxycortisol as a marker of human hepatic cytochrome P450IIIA induction
-
Ged C., Rouillon J.M., Pichard L., Combalbert J., Bressot N., Bories P., Michel H., Beaune P., and Maurel P. The increase in urinary excretion of 6;gb-hydroxycortisol as a marker of human hepatic cytochrome P450IIIA induction. Br. J. Clin. Pharmacol. 28 (1989) 373-387
-
(1989)
Br. J. Clin. Pharmacol.
, vol.28
, pp. 373-387
-
-
Ged, C.1
Rouillon, J.M.2
Pichard, L.3
Combalbert, J.4
Bressot, N.5
Bories, P.6
Michel, H.7
Beaune, P.8
Maurel, P.9
-
47
-
-
0025755576
-
Induction of drug-metabolizing enzymes
-
Gibaldi M. Induction of drug-metabolizing enzymes. Perspect. Clin. Pharm. 9 6 (1991) 41-46
-
(1991)
Perspect. Clin. Pharm.
, vol.9
, Issue.6
, pp. 41-46
-
-
Gibaldi, M.1
-
48
-
-
0025827880
-
Inducing effect of oxfendazole on cytochrome P4501A2 in rabbit liver. Consequences on cytochrome P450 dependent monooxygenases
-
Gleizes C., Eeckhoutte C., Pineau T., Alvinerie M., and Galtier P. Inducing effect of oxfendazole on cytochrome P4501A2 in rabbit liver. Consequences on cytochrome P450 dependent monooxygenases. Biochem. Pharmacol. 41 12 (1991) 1813-1820
-
(1991)
Biochem. Pharmacol.
, vol.41
, Issue.12
, pp. 1813-1820
-
-
Gleizes, C.1
Eeckhoutte, C.2
Pineau, T.3
Alvinerie, M.4
Galtier, P.5
-
49
-
-
0018092881
-
Genetic variation in N-acetylation of carcinogenic arylamines by human and rabbit liver
-
Glowinski I.B., Radtke H.E., and Weber W.W. Genetic variation in N-acetylation of carcinogenic arylamines by human and rabbit liver. Mol. Pharmacol. 14 (1978) 940-949
-
(1978)
Mol. Pharmacol.
, vol.14
, pp. 940-949
-
-
Glowinski, I.B.1
Radtke, H.E.2
Weber, W.W.3
-
50
-
-
0018933224
-
The expanding role of microsomal enzyme induction, and its implications for clinical chemistry
-
Goldberg D.M. The expanding role of microsomal enzyme induction, and its implications for clinical chemistry. Clin. Chem. 26 6 (1980) 691-699
-
(1980)
Clin. Chem.
, vol.26
, Issue.6
, pp. 691-699
-
-
Goldberg, D.M.1
-
51
-
-
0028272001
-
Role of human cytochromes P450 in the metabolic activation of chemical carcinogens and toxins
-
Gonzalez F.J., and Gelboin H.V. Role of human cytochromes P450 in the metabolic activation of chemical carcinogens and toxins. Drug Metab. Rev. 26 1&2 (1994) 165-183
-
(1994)
Drug Metab. Rev.
, vol.26
, Issue.1-2
, pp. 165-183
-
-
Gonzalez, F.J.1
Gelboin, H.V.2
-
52
-
-
0027409436
-
Regulation of cytochrome P450 genes: Molecular mechanisms
-
Liu Gonzalez F.J., and Yano S.Y.M. Regulation of cytochrome P450 genes: Molecular mechanisms. Pharmacogenetics 3 (1993) 51-57
-
(1993)
Pharmacogenetics
, vol.3
, pp. 51-57
-
-
Liu Gonzalez, F.J.1
Yano, S.Y.M.2
-
53
-
-
0028031172
-
Clinically significant drug interactions with antituberculosis agents
-
Grange J.M., Winstanley P.A., and Davies P.D.O. Clinically significant drug interactions with antituberculosis agents. Drug Saf. 11 4 (1994) 242-251
-
(1994)
Drug Saf.
, vol.11
, Issue.4
, pp. 242-251
-
-
Grange, J.M.1
Winstanley, P.A.2
Davies, P.D.O.3
-
54
-
-
0025878351
-
Role of persistent, non-genotoxic tissue damage in rodent cancer and relevance to humans
-
Grasso P., Sharratt M., and Cohen A.J. Role of persistent, non-genotoxic tissue damage in rodent cancer and relevance to humans. Annu. Rev. Pharmacol. Toxicol. 31 (1991) 253-287
-
(1991)
Annu. Rev. Pharmacol. Toxicol.
, vol.31
, pp. 253-287
-
-
Grasso, P.1
Sharratt, M.2
Cohen, A.J.3
-
55
-
-
0028965804
-
Activity of hepatic drug metabolizing enzymes following oxazepam-dosed feed treatment in B6C3F1 mice
-
Griffin R.J., Burka L.T., and Cunningham M.L. Activity of hepatic drug metabolizing enzymes following oxazepam-dosed feed treatment in B6C3F1 mice. Toxicol. Lett. 76 (1995) 251-256
-
(1995)
Toxicol. Lett.
, vol.76
, pp. 251-256
-
-
Griffin, R.J.1
Burka, L.T.2
Cunningham, M.L.3
-
56
-
-
0020028678
-
Estimation of isozymes of microsomal cytochrome P-450 in rats, rabbits, and humans using immunochemical staining coupled with sodium dodecyl sulfate-polyacrylamide gel electrophoresis
-
Guengerich F.P., Wang P., and Davidson N.K. Estimation of isozymes of microsomal cytochrome P-450 in rats, rabbits, and humans using immunochemical staining coupled with sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Biochemistry 21 (1982) 1698-1706
-
(1982)
Biochemistry
, vol.21
, pp. 1698-1706
-
-
Guengerich, F.P.1
Wang, P.2
Davidson, N.K.3
-
57
-
-
0016275313
-
Glutathione transferases: The first step in mercapturic acid formation
-
Habig W.H., Pabst M.J., and Jakoby W.B. Glutathione transferases: The first step in mercapturic acid formation. J. Biol. Chem. 249 (1974) 7130-7139
-
(1974)
J. Biol. Chem.
, vol.249
, pp. 7130-7139
-
-
Habig, W.H.1
Pabst, M.J.2
Jakoby, W.B.3
-
58
-
-
0015597281
-
Multiple N-acetyltransferases and drug metabolism, tissue distribution, characterization and significance of mammalian N-acetyltransferase
-
Hearse D.J., and Weber W.W. Multiple N-acetyltransferases and drug metabolism, tissue distribution, characterization and significance of mammalian N-acetyltransferase. Biochem. J. 132 (1973) 519-526
-
(1973)
Biochem. J.
, vol.132
, pp. 519-526
-
-
Hearse, D.J.1
Weber, W.W.2
-
59
-
-
0000747053
-
Carboxylesterases and amidases
-
Jakoby W.B. (Ed), Academic Press, New York
-
Heymann E. Carboxylesterases and amidases. In: Jakoby W.B. (Ed). "Enzymatic Basis of Detoxication" 2 (1980), Academic Press, New York 291-323
-
(1980)
"Enzymatic Basis of Detoxication"
, vol.2
, pp. 291-323
-
-
Heymann, E.1
-
60
-
-
0018863127
-
Effect of administration route of 3-methylcholanthrene on the inducibility of intestinal drug-metabolizing enzymes
-
Hietanen E., Laitinen M., and Koivusaari U. Effect of administration route of 3-methylcholanthrene on the inducibility of intestinal drug-metabolizing enzymes. Enzyme 25 (1980) 153-157
-
(1980)
Enzyme
, vol.25
, pp. 153-157
-
-
Hietanen, E.1
Laitinen, M.2
Koivusaari, U.3
-
61
-
-
77957181978
-
Thyroid follicular cell carcinogenesis
-
Hill R.N., Erdreich L.S., Paynter O.E., Roberts P.A., Rosenthal S.L., and Wilkinson C.F. Thyroid follicular cell carcinogenesis. Fundam. Appl. Toxicol. 12 4 (1989) 629-697
-
(1989)
Fundam. Appl. Toxicol.
, vol.12
, Issue.4
, pp. 629-697
-
-
Hill, R.N.1
Erdreich, L.S.2
Paynter, O.E.3
Roberts, P.A.4
Rosenthal, S.L.5
Wilkinson, C.F.6
-
62
-
-
0023180455
-
Multiplicity and regulation of hepatic microsomal carboxylesterases in rats
-
Hosokawa M., Maki T., and Satoh T. Multiplicity and regulation of hepatic microsomal carboxylesterases in rats. Mol. Pharmacol. 31 (1987) 579-584
-
(1987)
Mol. Pharmacol.
, vol.31
, pp. 579-584
-
-
Hosokawa, M.1
Maki, T.2
Satoh, T.3
-
63
-
-
0025261405
-
Characterization of molecular species of liver microsomal carboxylesterases of several animal species and humans
-
Hosokawa M., Maki T., and Satoh T. Characterization of molecular species of liver microsomal carboxylesterases of several animal species and humans. Arch. Biochem. Biophys. 277 (1990) 219-227
-
(1990)
Arch. Biochem. Biophys.
, vol.277
, pp. 219-227
-
-
Hosokawa, M.1
Maki, T.2
Satoh, T.3
-
64
-
-
0028072775
-
Species differences in the induction of hepatic microsomal carboxylesterases caused by dietary exposure to di(2-ethlhexyl)phthalate, a peroxisome proliferator
-
Hosokawa M., Hirata K., Nakata F., Suga T., and Satoh T. Species differences in the induction of hepatic microsomal carboxylesterases caused by dietary exposure to di(2-ethlhexyl)phthalate, a peroxisome proliferator. Drug Metab. Dispos. 22 6 (1994) 889-894
-
(1994)
Drug Metab. Dispos.
, vol.22
, Issue.6
, pp. 889-894
-
-
Hosokawa, M.1
Hirata, K.2
Nakata, F.3
Suga, T.4
Satoh, T.5
-
65
-
-
0025741754
-
Comparative biochemical and morphometric changes associated with induction of the hepatic mixed function oxidase system in the rat
-
Howard M.O., Schwartz L.W., Newton J.F., Qualls C.W., Yodis L.A.P., and Ventre J.R. Comparative biochemical and morphometric changes associated with induction of the hepatic mixed function oxidase system in the rat. Toxicol. Pathol. 19 2 (1991) 115-122
-
(1991)
Toxicol. Pathol.
, vol.19
, Issue.2
, pp. 115-122
-
-
Howard, M.O.1
Schwartz, L.W.2
Newton, J.F.3
Qualls, C.W.4
Yodis, L.A.P.5
Ventre, J.R.6
-
66
-
-
0026691486
-
Studies on the biochemical effects of the aldose reductase inhibitor 2, 7-difluorospirofluorene- 9, 5′-imidazolidine-2′, 4′-dione (A1 1576, HOE 843). Detection of D-glucaric and D-glucuronic acid excretion by high resolution 1H and 13C NMR spectroscopy
-
Hoyle V.R., Gilbert P.J., Troke J.A., Vose C.W., and Nicholson J.K. Studies on the biochemical effects of the aldose reductase inhibitor 2, 7-difluorospirofluorene- 9, 5′-imidazolidine-2′, 4′-dione (A1 1576, HOE 843). Detection of D-glucaric and D-glucuronic acid excretion by high resolution 1H and 13C NMR spectroscopy. Biochem. Pharmacol. 44 2 (1992) 231-241
-
(1992)
Biochem. Pharmacol.
, vol.44
, Issue.2
, pp. 231-241
-
-
Hoyle, V.R.1
Gilbert, P.J.2
Troke, J.A.3
Vose, C.W.4
Nicholson, J.K.5
-
67
-
-
0015233470
-
Urinary D-glucaric-acid excretion as a test for hepatic enzyme induction in man
-
Hunter J., Maxwell J.D., Carrella M., Stewart D.A., and Williams R. Urinary D-glucaric-acid excretion as a test for hepatic enzyme induction in man. Lancet 1 699 (1971) 572-575
-
(1971)
Lancet
, vol.1
, Issue.699
, pp. 572-575
-
-
Hunter, J.1
Maxwell, J.D.2
Carrella, M.3
Stewart, D.A.4
Williams, R.5
-
68
-
-
0023706607
-
Aminopyrine metabolism by multiple forms of cytochrome P-450 from rat liver microsomes: Simultaneous quantitation of four aminopyrine metabolites by high-performance liquid chromatography
-
Imaoka S., Inoue K., and Funae Y. Aminopyrine metabolism by multiple forms of cytochrome P-450 from rat liver microsomes: Simultaneous quantitation of four aminopyrine metabolites by high-performance liquid chromatography. Arch. Biochem. Biophys. 265 1 (1988) 159-170
-
(1988)
Arch. Biochem. Biophys.
, vol.265
, Issue.1
, pp. 159-170
-
-
Imaoka, S.1
Inoue, K.2
Funae, Y.3
-
69
-
-
0028138480
-
Simultaneous high performance liquid chromatographic determination of 6β-hydroxycortisol and cortisol in urine with fluorescence detection and its application for estimating hepatic drug-metabolizing enzyme induction
-
Inoue S., Inokuma M., Harada T., Shibutani Y., Yoshitake T., Charles B., Ishida J., and Yamaguchi M. Simultaneous high performance liquid chromatographic determination of 6β-hydroxycortisol and cortisol in urine with fluorescence detection and its application for estimating hepatic drug-metabolizing enzyme induction. J. Chromatogr. B: Biomed. Appl. 661 (1994) 15-23
-
(1994)
J. Chromatogr. B: Biomed. Appl.
, vol.661
, pp. 15-23
-
-
Inoue, S.1
Inokuma, M.2
Harada, T.3
Shibutani, Y.4
Yoshitake, T.5
Charles, B.6
Ishida, J.7
Yamaguchi, M.8
-
70
-
-
0023522162
-
Commentary: The cytochromes P-448-a unique family of enzymes involved in chemical toxicity and carcinogenesis
-
Ioannides C., and Parke D.V. Commentary: The cytochromes P-448-a unique family of enzymes involved in chemical toxicity and carcinogenesis. Biochem. Pharmacol. 36 24 (1987) 4197-4207
-
(1987)
Biochem. Pharmacol.
, vol.36
, Issue.24
, pp. 4197-4207
-
-
Ioannides, C.1
Parke, D.V.2
-
71
-
-
0027751340
-
Induction of cytochrome P4501 as an indicator of potential chemical carcinogenesis
-
Ioannides C., and Parke D.V. Induction of cytochrome P4501 as an indicator of potential chemical carcinogenesis. Drug Metab. Rev. 25 4 (1993) 485-501
-
(1993)
Drug Metab. Rev.
, vol.25
, Issue.4
, pp. 485-501
-
-
Ioannides, C.1
Parke, D.V.2
-
72
-
-
0027970864
-
Liver enzyme induction and serum lipid levels after replacement of carbamazepine with oxcarbazepine
-
Isojärvi J.I.T., Pakarinen A.J., Rautio A., Pelkonen O., and Myllylä V.V. Liver enzyme induction and serum lipid levels after replacement of carbamazepine with oxcarbazepine. Epilepsia 35 6 (1994) 1217-1220
-
(1994)
Epilepsia
, vol.35
, Issue.6
, pp. 1217-1220
-
-
Isojärvi, J.I.T.1
Pakarinen, A.J.2
Rautio, A.3
Pelkonen, O.4
Myllylä, V.V.5
-
73
-
-
0021922120
-
Microsomal cytochrome P-450 "handprints": Five fractions from anion-exchange high-pressure liquid chromatography provide a rapid preliminary screen for selectivity in the induction and destruction of rat hepatic cytochrome P-450 subpopulations
-
Iversen P.L., and Franklin M.R. Microsomal cytochrome P-450 "handprints": Five fractions from anion-exchange high-pressure liquid chromatography provide a rapid preliminary screen for selectivity in the induction and destruction of rat hepatic cytochrome P-450 subpopulations. Toxicol. Appl. Pharmacol. 78 (1985) 1-9
-
(1985)
Toxicol. Appl. Pharmacol.
, vol.78
, pp. 1-9
-
-
Iversen, P.L.1
Franklin, M.R.2
-
74
-
-
0025872863
-
Identification of the cytochrome P-450 IIIA family as the enzymes involved in the N-demethylation of tamoxifen in human liver microsomes
-
Jacolot F., Simon I., Dreano Y., Beaune P., Riche C., and Berthou F. Identification of the cytochrome P-450 IIIA family as the enzymes involved in the N-demethylation of tamoxifen in human liver microsomes. Biochem. Pharmacol. 41 (1991) 1911-1919
-
(1991)
Biochem. Pharmacol.
, vol.41
, pp. 1911-1919
-
-
Jacolot, F.1
Simon, I.2
Dreano, Y.3
Beaune, P.4
Riche, C.5
Berthou, F.6
-
75
-
-
0026907361
-
Induction of various cytochromes CYP2B, CYP2C and CYP3A by phenobarbitone in non-human primates
-
Jones C.R., Guengerich F.P., Rice J.M., and Lubet R.A. Induction of various cytochromes CYP2B, CYP2C and CYP3A by phenobarbitone in non-human primates. Pharmacogenetics 2 (1992) 160-172
-
(1992)
Pharmacogenetics
, vol.2
, pp. 160-172
-
-
Jones, C.R.1
Guengerich, F.P.2
Rice, J.M.3
Lubet, R.A.4
-
76
-
-
0025969276
-
Caffeine as a metabolic probe: Exploration of the enzymeinducing effect of cigarette smoking
-
Kalow W., and Tang B.K. Caffeine as a metabolic probe: Exploration of the enzymeinducing effect of cigarette smoking. Clin. Pharmacol. Ther. 49 (1991) 44-48
-
(1991)
Clin. Pharmacol. Ther.
, vol.49
, pp. 44-48
-
-
Kalow, W.1
Tang, B.K.2
-
78
-
-
0027159323
-
Single-dose disulfiram inhibition of chlorzoxazone metabolism: A clinical probe for P450 2E1
-
Kharasch E.D., Thummel K.E., Mhyre J., and Lillibridge J.H. Single-dose disulfiram inhibition of chlorzoxazone metabolism: A clinical probe for P450 2E1. Clin. Pharmacol. Ther. 53 6 (1993) 643-650
-
(1993)
Clin. Pharmacol. Ther.
, vol.53
, Issue.6
, pp. 643-650
-
-
Kharasch, E.D.1
Thummel, K.E.2
Mhyre, J.3
Lillibridge, J.H.4
-
79
-
-
0028918996
-
Comparative analysis of cytochrome P4503A induction in primary cultures of rat, rabbit, and human hepatocytes
-
Kocarek T.A., Schuetz E.G., Strom S.C., Fisher R.A., and Guzelian P.S. Comparative analysis of cytochrome P4503A induction in primary cultures of rat, rabbit, and human hepatocytes. Drug Metab. Dispos. 23 3 (1995) 415-421
-
(1995)
Drug Metab. Dispos.
, vol.23
, Issue.3
, pp. 415-421
-
-
Kocarek, T.A.1
Schuetz, E.G.2
Strom, S.C.3
Fisher, R.A.4
Guzelian, P.S.5
-
80
-
-
0022494453
-
Hydroxylation of para-nitrophenol by rabbit ethanol inducible cytochrome P-450 isozyme 3A
-
Koop D.R. Hydroxylation of para-nitrophenol by rabbit ethanol inducible cytochrome P-450 isozyme 3A. Mol. Pharmacol. 29 (1986) 399-404
-
(1986)
Mol. Pharmacol.
, vol.29
, pp. 399-404
-
-
Koop, D.R.1
-
81
-
-
0029146509
-
Ethanol and isopentanol increase CYP3A and CYP2E in primary cultures of human hepatocytes
-
Kostrubsky V.E., Strom S.C., Wood S.G., Wrighton S.A., Sinclair P.R., and Sinclair J.F. Ethanol and isopentanol increase CYP3A and CYP2E in primary cultures of human hepatocytes. Arch. Biochem. Biophys. 322 (1995) 516-520
-
(1995)
Arch. Biochem. Biophys.
, vol.322
, pp. 516-520
-
-
Kostrubsky, V.E.1
Strom, S.C.2
Wood, S.G.3
Wrighton, S.A.4
Sinclair, P.R.5
Sinclair, J.F.6
-
82
-
-
0020331435
-
The caffeine CO2 breath test: Dose response and route of N-demethylation in smokers and nonsmokers
-
Kotake A.N., Schoeller D.A., Lambert G.H., Baker A.L., Schaffer D.D., and Josephs H. The caffeine CO2 breath test: Dose response and route of N-demethylation in smokers and nonsmokers. Clin. Pharmacol. Ther. 32 2 (1982) 261-269
-
(1982)
Clin. Pharmacol. Ther.
, vol.32
, Issue.2
, pp. 261-269
-
-
Kotake, A.N.1
Schoeller, D.A.2
Lambert, G.H.3
Baker, A.L.4
Schaffer, D.D.5
Josephs, H.6
-
83
-
-
0022511846
-
Use of a low-speed iso-density Percoll centrifugation method to increase the viability of isolated hepatocyte preparations
-
Kreamer B.L., Staecker J.L., Sawada N., Sattler G.L., Hsia M.T.S., and Pitot H.C. Use of a low-speed iso-density Percoll centrifugation method to increase the viability of isolated hepatocyte preparations. In Vitro 22 (1986) 201
-
(1986)
In Vitro
, vol.22
, pp. 201
-
-
Kreamer, B.L.1
Staecker, J.L.2
Sawada, N.3
Sattler, G.L.4
Hsia, M.T.S.5
Pitot, H.C.6
-
84
-
-
0026724265
-
Autoinduction and steady-state pharmacokinetics of carbamazepine and its major metabolites
-
Kudriakova T.B., Sirota L.A., Rozova G.I., and Gorkov V.A. Autoinduction and steady-state pharmacokinetics of carbamazepine and its major metabolites. Br. J. Clin. Pharmacol. 33 (1992) 611-615
-
(1992)
Br. J. Clin. Pharmacol.
, vol.33
, pp. 611-615
-
-
Kudriakova, T.B.1
Sirota, L.A.2
Rozova, G.I.3
Gorkov, V.A.4
-
85
-
-
0014949207
-
Cleavage of structural proteins during the assembly of the head of bacteriophage T4
-
Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (London) 227 (1970) 680-685
-
(1970)
Nature (London)
, vol.227
, pp. 680-685
-
-
Laemmli, U.K.1
-
86
-
-
0027212381
-
Induction of cytochrome P-450-dependent enzyme activities in cultured rat liver slices
-
Lake B.G., Beamand J.A., Japenga A.C., Renwick A., Davies S., and Price R.J. Induction of cytochrome P-450-dependent enzyme activities in cultured rat liver slices. Food Chem. Toxicol. 31 5 (1993) 377-386
-
(1993)
Food Chem. Toxicol.
, vol.31
, Issue.5
, pp. 377-386
-
-
Lake, B.G.1
Beamand, J.A.2
Japenga, A.C.3
Renwick, A.4
Davies, S.5
Price, R.J.6
-
87
-
-
0020624033
-
Induction of hepatic drug-metabolizing enzymes in rats, dogs, and monkeys after repeated administration of an anti-inflammatory hexahydroindazole
-
Lan S.J., Weinstein S.H., Keim G.R., and Migdalof B.H. Induction of hepatic drug-metabolizing enzymes in rats, dogs, and monkeys after repeated administration of an anti-inflammatory hexahydroindazole. Xenobiotica 13 6 (1983) 329-335
-
(1983)
Xenobiotica
, vol.13
, Issue.6
, pp. 329-335
-
-
Lan, S.J.1
Weinstein, S.H.2
Keim, G.R.3
Migdalof, B.H.4
-
88
-
-
0022649901
-
Drug pharmacokinetics and the carbon dioxide breath test
-
Lane E.A., and Parashos I. Drug pharmacokinetics and the carbon dioxide breath test. J. Pharmacokinet. Biopharm. 14 1 (1986) 29-49
-
(1986)
J. Pharmacokinet. Biopharm.
, vol.14
, Issue.1
, pp. 29-49
-
-
Lane, E.A.1
Parashos, I.2
-
89
-
-
0001025688
-
Isolation and culturing of hepatocytes from human liver
-
Li A.P., Roque M.A., Beck D.J., and Kaminski D.L. Isolation and culturing of hepatocytes from human liver. J. Tissue Cult, Methods 14 (1992) 139-146
-
(1992)
J. Tissue Cult, Methods
, vol.14
, pp. 139-146
-
-
Li, A.P.1
Roque, M.A.2
Beck, D.J.3
Kaminski, D.L.4
-
90
-
-
0029021932
-
Rifampincin induction of lidocaine metabolism in cultured human hepatocytes
-
Li A.P., Rasmussen A., Xu L., and Kaminiski D.L. Rifampincin induction of lidocaine metabolism in cultured human hepatocytes. J. Pharmacol. Exp. Ther. 274 (1995) 673-677
-
(1995)
J. Pharmacol. Exp. Ther.
, vol.274
, pp. 673-677
-
-
Li, A.P.1
Rasmussen, A.2
Xu, L.3
Kaminiski, D.L.4
-
91
-
-
0029584276
-
Substrates of human hepatic cytochrome P450 3A4
-
Li A.P., Kaminski D.L., and Rasmussen A. Substrates of human hepatic cytochrome P450 3A4. Toxicology 104 (1995) 1-8
-
(1995)
Toxicology
, vol.104
, pp. 1-8
-
-
Li, A.P.1
Kaminski, D.L.2
Rasmussen, A.3
-
92
-
-
0028847788
-
Pharmacokinetics and drug disposition. The erythromycin breath test predicts the clearance of midazolam
-
Lown K.S., Thummel K.E., Benedict P.E., Shen D.D., Turgeon D.K., Berent S., and Watkins P.B. Pharmacokinetics and drug disposition. The erythromycin breath test predicts the clearance of midazolam. Clin. Pharmacol. Ther. 57 (1995) 16-24
-
(1995)
Clin. Pharmacol. Ther.
, vol.57
, pp. 16-24
-
-
Lown, K.S.1
Thummel, K.E.2
Benedict, P.E.3
Shen, D.D.4
Turgeon, D.K.5
Berent, S.6
Watkins, P.B.7
-
94
-
-
0022350885
-
Dealkylation of pentoxyresorufin: A rapid and sensitive assay for measuring induction of cytochrome(s) P-450 by phenobarbital and other xenobiotics in the rat
-
Lubet R.A., Mayer R.T., Cameron J.W., Nims R.W., Burke M.D., Wolff T., and Guengerich F.P. Dealkylation of pentoxyresorufin: A rapid and sensitive assay for measuring induction of cytochrome(s) P-450 by phenobarbital and other xenobiotics in the rat. Arch. Biochem. Biophys. 238 1 (1985) 43-48
-
(1985)
Arch. Biochem. Biophys.
, vol.238
, Issue.1
, pp. 43-48
-
-
Lubet, R.A.1
Mayer, R.T.2
Cameron, J.W.3
Nims, R.W.4
Burke, M.D.5
Wolff, T.6
Guengerich, F.P.7
-
95
-
-
0024524508
-
Induction of cytochrome P450b and its relationship to liver tumor promotion
-
Lubet R.A., Nims R.W., Ward J.M., Rice J.M., and Diwan B.A. Induction of cytochrome P450b and its relationship to liver tumor promotion. J. Am. Coll. Toxicol. 8 2 (1989) 259-268
-
(1989)
J. Am. Coll. Toxicol.
, vol.8
, Issue.2
, pp. 259-268
-
-
Lubet, R.A.1
Nims, R.W.2
Ward, J.M.3
Rice, J.M.4
Diwan, B.A.5
-
96
-
-
0023940612
-
Microsomal enzyme induction, lipoproteins and atherosclerosis
-
Luoma P.V. Microsomal enzyme induction, lipoproteins and atherosclerosis. Pharmacol. Toxicol. 62 (1988) 243-249
-
(1988)
Pharmacol. Toxicol.
, vol.62
, pp. 243-249
-
-
Luoma, P.V.1
-
97
-
-
0019969512
-
Preparation of human hepatocytes from primary culture
-
Maekubo H., Ozaki S., Mitmaker B., and Kalant N. Preparation of human hepatocytes from primary culture. In Vitro 18 (1982) 483-491
-
(1982)
In Vitro
, vol.18
, pp. 483-491
-
-
Maekubo, H.1
Ozaki, S.2
Mitmaker, B.3
Kalant, N.4
-
98
-
-
0030028139
-
In vivo induction of cytochrome P450 CYP3A expression in rat leukocytes using various inducers
-
Mahnke A., Roos P.H., Hanstein W.G., and Chabot G.G. In vivo induction of cytochrome P450 CYP3A expression in rat leukocytes using various inducers. Biochem. Pharmacol. 51 (1996) 1579-1582
-
(1996)
Biochem. Pharmacol.
, vol.51
, pp. 1579-1582
-
-
Mahnke, A.1
Roos, P.H.2
Hanstein, W.G.3
Chabot, G.G.4
-
99
-
-
0003009327
-
Experiments illustrating drug metabolism in vitro
-
LaDu B.N., Mandel H.G., and Way E.L. (Eds), Williams & Wilkins, Baltimore
-
Mazel P. Experiments illustrating drug metabolism in vitro. In: LaDu B.N., Mandel H.G., and Way E.L. (Eds). "Fundamentals of Drug Metabolism and Disposition" (1971), Williams & Wilkins, Baltimore 546-550
-
(1971)
"Fundamentals of Drug Metabolism and Disposition"
, pp. 546-550
-
-
Mazel, P.1
-
100
-
-
0023785943
-
Drug interactions that matter. A critical reappraisal
-
McInnes G.T., and Brodie M.J. Drug interactions that matter. A critical reappraisal. Drugs 36 (1988) 83-110
-
(1988)
Drugs
, vol.36
, pp. 83-110
-
-
McInnes, G.T.1
Brodie, M.J.2
-
101
-
-
0022384124
-
Effects of phenobarbitone and β-naphthoflavone on hepatic microsomal drug metabolising enzymes of the male beagle dog
-
McKillop D. Effects of phenobarbitone and β-naphthoflavone on hepatic microsomal drug metabolising enzymes of the male beagle dog. Biochem. Pharmacol. 34 17 (1985) 3137-3142
-
(1985)
Biochem. Pharmacol.
, vol.34
, Issue.17
, pp. 3137-3142
-
-
McKillop, D.1
-
102
-
-
84973743864
-
Is enzyme induction good for you? A problem of epidemiology and toxicology
-
McLean A.E.M. Is enzyme induction good for you? A problem of epidemiology and toxicology. Hum. Toxicol. 7 (1988) 419-422
-
(1988)
Hum. Toxicol.
, vol.7
, pp. 419-422
-
-
McLean, A.E.M.1
-
103
-
-
0025367754
-
Expression of cytochrome P-450 enzymes in cultured human hepatocytes
-
Morel F., Beaune P.H., Ratanasavanh D., Flinois J.P., and Yang C.S. Expression of cytochrome P-450 enzymes in cultured human hepatocytes. Eur. J. Biochem. 191 2 (1990) 437-444
-
(1990)
Eur. J. Biochem.
, vol.191
, Issue.2
, pp. 437-444
-
-
Morel, F.1
Beaune, P.H.2
Ratanasavanh, D.3
Flinois, J.P.4
Yang, C.S.5
-
104
-
-
77049138167
-
The colorimetric estimation of formaldehyde by means of the Hantzsch reaction
-
Nash T. The colorimetric estimation of formaldehyde by means of the Hantzsch reaction. J. Biol. Chem. 55 (1953) 416-421
-
(1953)
J. Biol. Chem.
, vol.55
, pp. 416-421
-
-
Nash, T.1
-
105
-
-
0018680603
-
Multiple forms of inducible drug-metabolizing enzymes: A reasonable mechanism by which any organism can cope with adversity
-
Nebert D.W. Multiple forms of inducible drug-metabolizing enzymes: A reasonable mechanism by which any organism can cope with adversity. Mol. Cell. Biochem. 27 1 (1979) 27-46
-
(1979)
Mol. Cell. Biochem.
, vol.27
, Issue.1
, pp. 27-46
-
-
Nebert, D.W.1
-
106
-
-
0028662025
-
P450 in the rat and man: Methods of investigation, substrate specificities and relevance to cancer
-
Nedelcheva V., and Gut I. P450 in the rat and man: Methods of investigation, substrate specificities and relevance to cancer. Xenobiotica 24 12 (1994) 1151-1175
-
(1994)
Xenobiotica
, vol.24
, Issue.12
, pp. 1151-1175
-
-
Nedelcheva, V.1
Gut, I.2
-
107
-
-
0028960240
-
Comparative metabolism of 3′-azido-3′-deoxythymidine in cultured hepatocytes from rats, dogs, monkeys, and humans
-
Nicolas F., De Sousa G., Thomas P., Placidi M., Lorenzon G., and Rahmani R. Comparative metabolism of 3′-azido-3′-deoxythymidine in cultured hepatocytes from rats, dogs, monkeys, and humans. Drug Metab. Dispos. 23 3 (1995) 308-313
-
(1995)
Drug Metab. Dispos.
, vol.23
, Issue.3
, pp. 308-313
-
-
Nicolas, F.1
De Sousa, G.2
Thomas, P.3
Placidi, M.4
Lorenzon, G.5
Rahmani, R.6
-
108
-
-
0027092472
-
Induction of hepatic CYP1A in male F344/NCr rats by dietary exposure to Aroclor 1254: Examination of immunochemical, RNA, catalytic, and pharmacokinetic endpoints
-
Nims R.W., Beebe L.E., Dragnev K.H., Thomas P.E., Fox S.D., Issaq H.J., Jones C.R., and Lubet R.A. Induction of hepatic CYP1A in male F344/NCr rats by dietary exposure to Aroclor 1254: Examination of immunochemical, RNA, catalytic, and pharmacokinetic endpoints. Environ. Res. 59 2 (1992) 447-466
-
(1992)
Environ. Res.
, vol.59
, Issue.2
, pp. 447-466
-
-
Nims, R.W.1
Beebe, L.E.2
Dragnev, K.H.3
Thomas, P.E.4
Fox, S.D.5
Issaq, H.J.6
Jones, C.R.7
Lubet, R.A.8
-
109
-
-
0015217363
-
A radiometric assay for hepatic epoxide hydrase activity with {7-3H}styrene oxide
-
Oesch F., Jerina D.M., and Daly J. A radiometric assay for hepatic epoxide hydrase activity with {7-3H}styrene oxide. Biochim. Biophys. Acta 227 (1971) 685-691
-
(1971)
Biochim. Biophys. Acta
, vol.227
, pp. 685-691
-
-
Oesch, F.1
Jerina, D.M.2
Daly, J.3
-
110
-
-
0018386160
-
Measurement of urinary 6-;gb-hydroxycortisol excretion as an in vivo parameter in the clinical assessment of the microsomal enzyme-inducing capacity of antipyrine, phenobarbitone and rifampicin
-
Ohnhaus E.E., and Park B.K. Measurement of urinary 6-;gb-hydroxycortisol excretion as an in vivo parameter in the clinical assessment of the microsomal enzyme-inducing capacity of antipyrine, phenobarbitone and rifampicin. Eur. J. Pharmacol. 15 2 (1979) 139-145
-
(1979)
Eur. J. Pharmacol.
, vol.15
, Issue.2
, pp. 139-145
-
-
Ohnhaus, E.E.1
Park, B.K.2
-
111
-
-
0025055648
-
Enzyme induction in the cytochrome P-450 system
-
Okey A.B. Enzyme induction in the cytochrome P-450 system. Pharmacol. Ther. 45 (1990) 241-298
-
(1990)
Pharmacol. Ther.
, vol.45
, pp. 241-298
-
-
Okey, A.B.1
-
112
-
-
0022472879
-
Induction of drugmetabolising enzymes: Mechanisms and consequences
-
Okey A.B., Roberts E.A., Harper P.A., and Denison M.S. Induction of drugmetabolising enzymes: Mechanisms and consequences. Clin. Biochem. 19 (1986) 132-141
-
(1986)
Clin. Biochem.
, vol.19
, pp. 132-141
-
-
Okey, A.B.1
Roberts, E.A.2
Harper, P.A.3
Denison, M.S.4
-
113
-
-
0025277085
-
Induction and developmental expression of cytochrome P450IA1 messenger RNA in rat and human tissues: Detection by the polymerase chain reaction
-
Omiecinski C.J., Redlich C.A., and Costa P. Induction and developmental expression of cytochrome P450IA1 messenger RNA in rat and human tissues: Detection by the polymerase chain reaction. Cancer Res. 50 (1990) 4315-4321
-
(1990)
Cancer Res.
, vol.50
, pp. 4315-4321
-
-
Omiecinski, C.J.1
Redlich, C.A.2
Costa, P.3
-
114
-
-
78651165715
-
The carbon monoxide-binding pigment of liver microsomes
-
Omura T., and Sato R. The carbon monoxide-binding pigment of liver microsomes. J. Biol. Chem. 239 7 (1964) 2370-2378
-
(1964)
J. Biol. Chem.
, vol.239
, Issue.7
, pp. 2370-2378
-
-
Omura, T.1
Sato, R.2
-
115
-
-
0028942964
-
The pharmacokinetics of teniloxazine in healthy subjects and patients with hepatic cirrhosis
-
Orlando R., Benvenuti C., Mazzo M., and Palatini P. The pharmacokinetics of teniloxazine in healthy subjects and patients with hepatic cirrhosis. Br. J. Clin. Pharmacol. 39 4 (1995) 445-448
-
(1995)
Br. J. Clin. Pharmacol.
, vol.39
, Issue.4
, pp. 445-448
-
-
Orlando, R.1
Benvenuti, C.2
Mazzo, M.3
Palatini, P.4
-
116
-
-
0026536336
-
On the nature of nongenotoxic carcinogens. A unified theory including NGCs, co-carcinogens and promotors
-
Paolini M., Biagi G.L., Bauer C., and Cantelli-Forti G. On the nature of nongenotoxic carcinogens. A unified theory including NGCs, co-carcinogens and promotors. Mutat. Res. 281 4 (1992) 245-246
-
(1992)
Mutat. Res.
, vol.281
, Issue.4
, pp. 245-246
-
-
Paolini, M.1
Biagi, G.L.2
Bauer, C.3
Cantelli-Forti, G.4
-
117
-
-
0019832026
-
Clinical implications of enzyme induction and enzyme inhibition
-
Park B.K., and Breckenridge A.M. Clinical implications of enzyme induction and enzyme inhibition. Clin. Pharmacokinet. 6 (1981) 1-24
-
(1981)
Clin. Pharmacokinet.
, vol.6
, pp. 1-24
-
-
Park, B.K.1
Breckenridge, A.M.2
-
118
-
-
0026095802
-
The role of the cytochromes P450 in the detoxication and activation of drugs and other chemicals
-
Parke D.V., Ioannides C., and Lewis D.F.V. The role of the cytochromes P450 in the detoxication and activation of drugs and other chemicals. Can. J. Physiol. Pharmacol. 69 (1991) 537-549
-
(1991)
Can. J. Physiol. Pharmacol.
, vol.69
, pp. 537-549
-
-
Parke, D.V.1
Ioannides, C.2
Lewis, D.F.V.3
-
120
-
-
0025793209
-
Omeprazole and the induction of human cytochrome P-450: A response to concerns about potential adverse effects
-
Parkinson A., and Hurwitz A. Omeprazole and the induction of human cytochrome P-450: A response to concerns about potential adverse effects. Gastroenterology 100 4 (1991) 1157-1164
-
(1991)
Gastroenterology
, vol.100
, Issue.4
, pp. 1157-1164
-
-
Parkinson, A.1
Hurwitz, A.2
-
121
-
-
0028864296
-
Comparison of chloroguanide and mephenytoin for the in vivo assessment of genetically determined CYP2C19 activity in humans
-
Partovian C., Jacqz-Aigrain E., Keundjian A., Jaillon P., and Funck-Brentano C. Comparison of chloroguanide and mephenytoin for the in vivo assessment of genetically determined CYP2C19 activity in humans. Clin. Pharmacol. Ther. 58 3 (1995) 257-263
-
(1995)
Clin. Pharmacol. Ther.
, vol.58
, Issue.3
, pp. 257-263
-
-
Partovian, C.1
Jacqz-Aigrain, E.2
Keundjian, A.3
Jaillon, P.4
Funck-Brentano, C.5
-
122
-
-
0023184313
-
Clinical implications of hepatic microsomal enzyme induction by antiepileptic drugs
-
Perucca E. Clinical implications of hepatic microsomal enzyme induction by antiepileptic drugs. Pharmacol. Ther. 33 (1987) 139-144
-
(1987)
Pharmacol. Ther.
, vol.33
, pp. 139-144
-
-
Perucca, E.1
-
123
-
-
0025223625
-
Hydroxylation of chlorzoxazone as a specific probe for human liver cytochrome P-450IIE1
-
Peter R., Bocker R., Beaune P.H., Iwasaki M., Guengerich F.P., and Yang C.S. Hydroxylation of chlorzoxazone as a specific probe for human liver cytochrome P-450IIE1. Chem. Res. Toxicol. 3 6 (1990) 566-573
-
(1990)
Chem. Res. Toxicol.
, vol.3
, Issue.6
, pp. 566-573
-
-
Peter, R.1
Bocker, R.2
Beaune, P.H.3
Iwasaki, M.4
Guengerich, F.P.5
Yang, C.S.6
-
124
-
-
0025857783
-
-
Peter R., Bocker R., Beaune P.H., Iwasaki M., Guengerich F.P., and Yang C.S. Chem. Res. Toxicol. 4 3 (1991) 389
-
(1991)
Chem. Res. Toxicol.
, vol.4
, Issue.3
, pp. 389
-
-
Peter, R.1
Bocker, R.2
Beaune, P.H.3
Iwasaki, M.4
Guengerich, F.P.5
Yang, C.S.6
-
125
-
-
0025134337
-
Cyclosporin A drug interactions. Screening for inducers and inhibitors of cytochrome P-450 (cyclosporin A oxidase) in primary cultures of human hepatocytes and in liver microsomes
-
Pichard L., Fabre I., Fabre G., Domergue J., Saint Aubert B., Mourad G., and Maurel P. Cyclosporin A drug interactions. Screening for inducers and inhibitors of cytochrome P-450 (cyclosporin A oxidase) in primary cultures of human hepatocytes and in liver microsomes. Drug Metab. Dispos. 18 5 (1990) 595-606
-
(1990)
Drug Metab. Dispos.
, vol.18
, Issue.5
, pp. 595-606
-
-
Pichard, L.1
Fabre, I.2
Fabre, G.3
Domergue, J.4
Saint Aubert, B.5
Mourad, G.6
Maurel, P.7
-
126
-
-
0019219257
-
A rapid method for assaying the metabolism of 7-ethoxyresorufin by microsomal subcellular fractions
-
Pohl R., and Fouts J.R. A rapid method for assaying the metabolism of 7-ethoxyresorufin by microsomal subcellular fractions. Anal. Biochem. 107 (1980) 150-155
-
(1980)
Anal. Biochem.
, vol.107
, pp. 150-155
-
-
Pohl, R.1
Fouts, J.R.2
-
127
-
-
0020439501
-
Induction of the drug-metabolizing enzymes (review)
-
Poland A. Induction of the drug-metabolizing enzymes (review). IARC Sci. Publ. 39 (1982) 351-364
-
(1982)
IARC Sci. Publ.
, vol.39
, pp. 351-364
-
-
Poland, A.1
-
128
-
-
0015152279
-
The metabolism of aminopyrine in chick embryo hepatic cell culture: Effects of competitive substrates and carbon monoxide
-
Poland A., and Kappas A. The metabolism of aminopyrine in chick embryo hepatic cell culture: Effects of competitive substrates and carbon monoxide. Mol. Pharmacol. 7 6 (1971) 697-705
-
(1971)
Mol. Pharmacol.
, vol.7
, Issue.6
, pp. 697-705
-
-
Poland, A.1
Kappas, A.2
-
129
-
-
0019813219
-
Changes in the metabolic profiles of R-and S-warfarin and R- and S-phenprocoumon as a probe to categorize the effect of inducing agents on microsomal hydroxylases
-
Porter W.R., Wheeler C., and Trager W.F. Changes in the metabolic profiles of R-and S-warfarin and R- and S-phenprocoumon as a probe to categorize the effect of inducing agents on microsomal hydroxylases. Biochem. Pharmacol. 30 22 (1981) 3099-3104
-
(1981)
Biochem. Pharmacol.
, vol.30
, Issue.22
, pp. 3099-3104
-
-
Porter, W.R.1
Wheeler, C.2
Trager, W.F.3
-
130
-
-
0017070851
-
An improved assay for steroid glucuronyltransferase in rat liver microsomes
-
Rao G.S., Haueter G., Rao M.L., and Breuer H. An improved assay for steroid glucuronyltransferase in rat liver microsomes. Anal. Biochem. 74 (1976) 35-40
-
(1976)
Anal. Biochem.
, vol.74
, pp. 35-40
-
-
Rao, G.S.1
Haueter, G.2
Rao, M.L.3
Breuer, H.4
-
131
-
-
0023182895
-
Induction and its influence on human cancer
-
Remmer H. Induction and its influence on human cancer. Pharmacol. Ther. 33 (1987) 89-94
-
(1987)
Pharmacol. Ther.
, vol.33
, pp. 89-94
-
-
Remmer, H.1
-
132
-
-
0028208696
-
Enhancement of hepatocarcinogenesis and induction of specific cytochrome P450-dependent monooxygenase activities by the barbiturates allobarbital, aprobarbital, pentobarbital, secobarbital and 5-phenyl- and 5-ethylbarbituric acids
-
Rice J.M., Diwan B.A., Hu H., Ward J.M., Nims R.W., and Lubet R.A. Enhancement of hepatocarcinogenesis and induction of specific cytochrome P450-dependent monooxygenase activities by the barbiturates allobarbital, aprobarbital, pentobarbital, secobarbital and 5-phenyl- and 5-ethylbarbituric acids. Carcinogenesis (London) 15 2 (1994) 395-402
-
(1994)
Carcinogenesis (London)
, vol.15
, Issue.2
, pp. 395-402
-
-
Rice, J.M.1
Diwan, B.A.2
Hu, H.3
Ward, J.M.4
Nims, R.W.5
Lubet, R.A.6
-
133
-
-
0028114740
-
Use of in vitro human metabolism studies in drug development. An industrial perspective
-
Rodrigues A.D. Use of in vitro human metabolism studies in drug development. An industrial perspective. Biochem. Pharmacol 48 12 (1994) 2147-2156
-
(1994)
Biochem. Pharmacol
, vol.48
, Issue.12
, pp. 2147-2156
-
-
Rodrigues, A.D.1
-
134
-
-
0023875216
-
Determination of microsomal lauric acid hydroxylase activity by HPLC with flow-through radiochemical quantitation
-
Romano M.C., Straub K.M., Yodis Y.A.D., Eckardt R.D., and Newton J.F. Determination of microsomal lauric acid hydroxylase activity by HPLC with flow-through radiochemical quantitation. Anal. Biochem. 170 (1988) 83-93
-
(1988)
Anal. Biochem.
, vol.170
, pp. 83-93
-
-
Romano, M.C.1
Straub, K.M.2
Yodis, Y.A.D.3
Eckardt, R.D.4
Newton, J.F.5
-
135
-
-
0026620605
-
Dose dependent induction of CYP1A2 activity by omeprazole (Antra)
-
Rost K., Brösicke H., Scheffler M., and Roots I. Dose dependent induction of CYP1A2 activity by omeprazole (Antra). Int. J. Clin. Pharmacol. Ther. Toxicol. 30 11 (1992) 542-543
-
(1992)
Int. J. Clin. Pharmacol. Ther. Toxicol.
, vol.30
, Issue.11
, pp. 542-543
-
-
Rost, K.1
Brösicke, H.2
Scheffler, M.3
Roots, I.4
-
136
-
-
0028051743
-
Specific and dose-dependent enzyme induction by omeprazole in human beings
-
Rost K.L., Brösicke H., Heinemeyer G., and Roots I. Specific and dose-dependent enzyme induction by omeprazole in human beings. Hepatology 20 (1994) 1204-1212
-
(1994)
Hepatology
, vol.20
, pp. 1204-1212
-
-
Rost, K.L.1
Brösicke, H.2
Heinemeyer, G.3
Roots, I.4
-
137
-
-
0025139447
-
Purification and characterization of hepatic microsomal cytochrome P-450
-
Ryan D.E., and Levin W. Purification and characterization of hepatic microsomal cytochrome P-450. Pharmacol. Ther. 45 (1990) 153-239
-
(1990)
Pharmacol. Ther.
, vol.45
, pp. 153-239
-
-
Ryan, D.E.1
Levin, W.2
-
138
-
-
0018405140
-
Separation and characterization of highly purified forms of liver microsomal cytochrome P-450 from rats treated with polychlorinated biphenyls, phenobarbital, and 3-methylcholanthrene
-
Ryan D.E., Thomas P.E., Korzeniowski D., and Levin W. Separation and characterization of highly purified forms of liver microsomal cytochrome P-450 from rats treated with polychlorinated biphenyls, phenobarbital, and 3-methylcholanthrene. J. Biol. Chem. 254 (1979) 1365-1374
-
(1979)
J. Biol. Chem.
, vol.254
, pp. 1365-1374
-
-
Ryan, D.E.1
Thomas, P.E.2
Korzeniowski, D.3
Levin, W.4
-
139
-
-
0019161825
-
Hepatic microsomal cytochrome P-450 form rats treated with isosafrole
-
Ryan D.E., Thomas P.E., and Levin W. Hepatic microsomal cytochrome P-450 form rats treated with isosafrole. J. Biol. Chem. 255 (1980) 7941-7955
-
(1980)
J. Biol. Chem.
, vol.255
, pp. 7941-7955
-
-
Ryan, D.E.1
Thomas, P.E.2
Levin, W.3
-
140
-
-
0027208730
-
Urinary D-glucaric acid, a marker substance for microsomal enzyme induction. Methodological aspects, responses to alcohol and findings in workers exposed to toluene
-
Sandstad O., Osnes T., Skar V., and Osnes M. Urinary D-glucaric acid, a marker substance for microsomal enzyme induction. Methodological aspects, responses to alcohol and findings in workers exposed to toluene. Scand. J. Clin. Lab. Invest. 53 (1993) 327-333
-
(1993)
Scand. J. Clin. Lab. Invest.
, vol.53
, pp. 327-333
-
-
Sandstad, O.1
Osnes, T.2
Skar, V.3
Osnes, M.4
-
141
-
-
0027425138
-
Influence of rifampin on fleroxacin pharmacokinetics
-
Schrenzel J., Dayer P., Leemann T., Weidekamm E., Portmann R., and Lew D.P. Influence of rifampin on fleroxacin pharmacokinetics. Antimicrob. Agents Chemother. 37 10 (1993) 2132-2138
-
(1993)
Antimicrob. Agents Chemother.
, vol.37
, Issue.10
, pp. 2132-2138
-
-
Schrenzel, J.1
Dayer, P.2
Leemann, T.3
Weidekamm, E.4
Portmann, R.5
Lew, D.P.6
-
142
-
-
0018786980
-
Phenol sulfotransferases
-
Sekura R.D., and Jakoby W.B. Phenol sulfotransferases. J. Biol. Chem. 254 (1979) 5658-5663
-
(1979)
J. Biol. Chem.
, vol.254
, pp. 5658-5663
-
-
Sekura, R.D.1
Jakoby, W.B.2
-
144
-
-
0028231149
-
Mechanisms of non-genotoxic carcinogenesis
-
Shaw I.C., and Jones H.B. Mechanisms of non-genotoxic carcinogenesis. Trends Pharmacol. Sci. 15 (1994) 89-93
-
(1994)
Trends Pharmacol. Sci.
, vol.15
, pp. 89-93
-
-
Shaw, I.C.1
Jones, H.B.2
-
145
-
-
0028237729
-
Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: Studies with liver microsomes of 30 Japanese and 30 Caucasians
-
Shimada T., Yamazaki H., Mimura M., Inui Y., and Guengerich F.P. Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: Studies with liver microsomes of 30 Japanese and 30 Caucasians. J. Pharmacol. Exp. Ther. 270 1 (1994) 414-423
-
(1994)
J. Pharmacol. Exp. Ther.
, vol.270
, Issue.1
, pp. 414-423
-
-
Shimada, T.1
Yamazaki, H.2
Mimura, M.3
Inui, Y.4
Guengerich, F.P.5
-
146
-
-
0023836094
-
Induction of plasma and tissue enzymes by drugs: Significance in toxicological studies
-
Siest G., Batt A.M., Fournel-Gigleux S., Galteau M.M., Wellman-Bednawska M., Minn A., and Costesec A.A. Induction of plasma and tissue enzymes by drugs: Significance in toxicological studies. Xenobiotica 18 Suppl. 1 (1988) 21-34
-
(1988)
Xenobiotica
, vol.18
, Issue.SUPPL. 1
, pp. 21-34
-
-
Siest, G.1
Batt, A.M.2
Fournel-Gigleux, S.3
Galteau, M.M.4
Wellman-Bednawska, M.5
Minn, A.6
Costesec, A.A.7
-
147
-
-
0029932214
-
Time for a consistent approach to preparing and culturing hepatocytes
-
Skett P., and Bayliss M. Time for a consistent approach to preparing and culturing hepatocytes. Xenobiotica 26 1 (1996) 1-7
-
(1996)
Xenobiotica
, vol.26
, Issue.1
, pp. 1-7
-
-
Skett, P.1
Bayliss, M.2
-
148
-
-
0018581336
-
Classes of hepatic microsomal mixed function oxidase inducers
-
Snyder R., and Remmer H. Classes of hepatic microsomal mixed function oxidase inducers. Pharmacol. Ther. 7 (1979) 203-244
-
(1979)
Pharmacol. Ther.
, vol.7
, pp. 203-244
-
-
Snyder, R.1
Remmer, H.2
-
149
-
-
0023654735
-
Regulation of testosterone hydroxylation by rat liver microsomal cytochrome P-450
-
Sonderfan A.J., Arlotto M.P., Dutton D.R., McMillen S.M., and Parkinson A. Regulation of testosterone hydroxylation by rat liver microsomal cytochrome P-450. Arch. Biochem. Biophys. 255 (1987) 27-41
-
(1987)
Arch. Biochem. Biophys.
, vol.255
, pp. 27-41
-
-
Sonderfan, A.J.1
Arlotto, M.P.2
Dutton, D.R.3
McMillen, S.M.4
Parkinson, A.5
-
150
-
-
0026569805
-
Cytochromes P-450 in rats: Structures, functions, properties and relevant human forms (review)
-
Soucek P., and Gut I. Cytochromes P-450 in rats: Structures, functions, properties and relevant human forms (review). Xenobiotica 22 1 (1992) 83-103
-
(1992)
Xenobiotica
, vol.22
, Issue.1
, pp. 83-103
-
-
Soucek, P.1
Gut, I.2
-
151
-
-
0026703155
-
Cytochrome P-450 induction in human lung tumor-derived cell lines. Characterization and effect of inflammatory mediators
-
Stanley L.A., Carmichael J., and Wolf C.R. Cytochrome P-450 induction in human lung tumor-derived cell lines. Characterization and effect of inflammatory mediators. Eur. J. Biochem. 208 (1992) 521-529
-
(1992)
Eur. J. Biochem.
, vol.208
, pp. 521-529
-
-
Stanley, L.A.1
Carmichael, J.2
Wolf, C.R.3
-
152
-
-
0028953763
-
Induction of cytochrome P4501A1 by aryl hydrocarbon receptor agonists in porcine aorta endothelial cells in culture and cytochrome P4501A1 activity in intact cells
-
Stegeman J.J., Hahn M.E., Weisbrod R., Woodin B.R., Joy J.S., Najibi S., and Cohen R.A. Induction of cytochrome P4501A1 by aryl hydrocarbon receptor agonists in porcine aorta endothelial cells in culture and cytochrome P4501A1 activity in intact cells. Mol. Pharmacol. 47 (1995) 296-306
-
(1995)
Mol. Pharmacol.
, vol.47
, pp. 296-306
-
-
Stegeman, J.J.1
Hahn, M.E.2
Weisbrod, R.3
Woodin, B.R.4
Joy, J.S.5
Najibi, S.6
Cohen, R.A.7
-
153
-
-
0025937736
-
A novel rat hepatic clofibrate-inducible cytochrome P450 that is not a lauric acid hydroxylase
-
Swinney D.C., Webb A.S., and Freedman R. A novel rat hepatic clofibrate-inducible cytochrome P450 that is not a lauric acid hydroxylase. Biochem. Pharmacol. 42 12 (1991) 2341-2349
-
(1991)
Biochem. Pharmacol.
, vol.42
, Issue.12
, pp. 2341-2349
-
-
Swinney, D.C.1
Webb, A.S.2
Freedman, R.3
-
154
-
-
0029151384
-
Ancillary approaches to toxicokinetic evaluations
-
Takacs A.R. Ancillary approaches to toxicokinetic evaluations. Toxicol. Pathol. 23 2 (1995) 179-186
-
(1995)
Toxicol. Pathol.
, vol.23
, Issue.2
, pp. 179-186
-
-
Takacs, A.R.1
-
155
-
-
0029558313
-
Chemoprotection against cancer by Phase 2 enzyme induction
-
Talalay P., Fahey J.W., Holtzclaw W.D., Prestera T., and Zhang Y. Chemoprotection against cancer by Phase 2 enzyme induction. Toxicol. Lett. 82/83 (1995) 173-179
-
(1995)
Toxicol. Lett.
, vol.82-83
, pp. 173-179
-
-
Talalay, P.1
Fahey, J.W.2
Holtzclaw, W.D.3
Prestera, T.4
Zhang, Y.5
-
156
-
-
0026460228
-
Co-regulation of phenytoin and tolbutamide metabolism in humans
-
Tassaneeyakul W., Veronese M.E., Birkett D.J., Doecke C.J., McManus M.E., Sansom L.N., and Miners J.O. Co-regulation of phenytoin and tolbutamide metabolism in humans. Br. J. Clin. Pharmacol. 34 6 (1992) 494-498
-
(1992)
Br. J. Clin. Pharmacol.
, vol.34
, Issue.6
, pp. 494-498
-
-
Tassaneeyakul, W.1
Veronese, M.E.2
Birkett, D.J.3
Doecke, C.J.4
McManus, M.E.5
Sansom, L.N.6
Miners, J.O.7
-
157
-
-
0021339284
-
Characterization of nine monoclonal antibodies against rat hepatic cytochrome P-450c
-
Thomas P.E., Reik L.M., Ryan D.E., and Levin W. Characterization of nine monoclonal antibodies against rat hepatic cytochrome P-450c. J. Biol. Chem. 259 (1984) 3890-3899
-
(1984)
J. Biol. Chem.
, vol.259
, pp. 3890-3899
-
-
Thomas, P.E.1
Reik, L.M.2
Ryan, D.E.3
Levin, W.4
-
158
-
-
0020422902
-
Effect of microsomal enzyme inducers on the soluble enzymes of hepatic phase II biotransformation
-
Thompson T.N., Watkins J.B., Gregus Z., and Klaassen C.D. Effect of microsomal enzyme inducers on the soluble enzymes of hepatic phase II biotransformation. Toxicol. Appl. Pharmacol. 66 (1982) 400-408
-
(1982)
Toxicol. Appl. Pharmacol.
, vol.66
, pp. 400-408
-
-
Thompson, T.N.1
Watkins, J.B.2
Gregus, Z.3
Klaassen, C.D.4
-
159
-
-
77956774753
-
-
T.N. Thompson J.G. Geary S.E. Unwin J.J. Dunn P.W. Brown D.R. Osborne K.K. Hwang 1990. Evaluation of ML 1012 as an hepatic enzyme inducer in rats, dogs, and monkeys. Abstr., North Am. International Society for the Study of Xenobiotics (ISSX) Meet., 3rd, San Diego, Ca, 1990, Abstr. No. 185
-
T.N. Thompson J.G. Geary S.E. Unwin J.J. Dunn P.W. Brown D.R. Osborne K.K. Hwang 1990). Evaluation of ML 1012 as an hepatic enzyme inducer in rats, dogs, and monkeys. Abstr., North Am. International Society for the Study of Xenobiotics (ISSX) Meet., 3rd, San Diego, Ca, 1990, Abstr. No. 185
-
-
-
-
160
-
-
0028114619
-
Use of midazolam as a human cytochrome P450 3A probe: I. In vitroin vivo correlations in liver transplant patients
-
Thummel K.E., Shen D.D., Podall T.D., Kunze K.L., Trager W.F., Hartwell P.S., Raisys V.A., Marsh C.L., McVicor J.P., Barr D.M., Perkins J.D., and Carithers Jr. R.L. Use of midazolam as a human cytochrome P450 3A probe: I. In vitroin vivo correlations in liver transplant patients. J. Pharmacol. Exp. Ther. 271 1 (1994) 549-556
-
(1994)
J. Pharmacol. Exp. Ther.
, vol.271
, Issue.1
, pp. 549-556
-
-
Thummel, K.E.1
Shen, D.D.2
Podall, T.D.3
Kunze, K.L.4
Trager, W.F.5
Hartwell, P.S.6
Raisys, V.A.7
Marsh, C.L.8
McVicor, J.P.9
Barr, D.M.10
Perkins, J.D.11
Carithers Jr., R.L.12
-
161
-
-
0009482260
-
Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications
-
Towbin H., Staehelin T., and Gordon J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications. Proc. Natl. Acad. Sci. U. S. A. 76 (1979) 4350-4354
-
(1979)
Proc. Natl. Acad. Sci. U. S. A.
, vol.76
, pp. 4350-4354
-
-
Towbin, H.1
Staehelin, T.2
Gordon, J.3
-
162
-
-
77956760629
-
-
J.E. Turner J.H. Leighton M. Cunningham S.L. Cox L.B. Hogan M.J. O'Sullivan 1994. The development of enzyme linked immunoadsorbent assays (ELISA's) for cytochrome P450's. Abstr. North Am. ISSX Meet., 6th, Raleigh, NC, 1994, Abstr. No. 180
-
J.E. Turner J.H. Leighton M. Cunningham S.L. Cox L.B. Hogan M.J. O'Sullivan 1994). The development of enzyme linked immunoadsorbent assays (ELISA's) for cytochrome P450's. Abstr. North Am. ISSX Meet., 6th, Raleigh, NC, 1994, Abstr. No. 180
-
-
-
-
163
-
-
0028168331
-
Metabolism of [3- 14C] coumarin by human liver microsomes
-
Van Iersel M.L., Henderson P.S.C.I., Walters D.G., Price R.J., Wolf C.R., and Lake B.G. Metabolism of [3- 14C] coumarin by human liver microsomes. Xenobiotica 24 8 (1994) 795-803
-
(1994)
Xenobiotica
, vol.24
, Issue.8
, pp. 795-803
-
-
Van Iersel, M.L.1
Henderson, P.S.C.I.2
Walters, D.G.3
Price, R.J.4
Wolf, C.R.5
Lake, B.G.6
-
164
-
-
0014269889
-
Determination of bilirubin glucuronide and assay of glucuronyltransferase with bilirubin as acceptor
-
VanRoy F.P., and Heirwegh K.P.M. Determination of bilirubin glucuronide and assay of glucuronyltransferase with bilirubin as acceptor. Biochem. J. 107 (1968) 507-518
-
(1968)
Biochem. J.
, vol.107
, pp. 507-518
-
-
VanRoy, F.P.1
Heirwegh, K.P.M.2
-
165
-
-
0026531077
-
Pharmacokinetic drug interactions with rifampicin
-
Venkatesan K. Pharmacokinetic drug interactions with rifampicin. Clin. Pharmacokinet. 22 1 (1992) 47-65
-
(1992)
Clin. Pharmacokinet.
, vol.22
, Issue.1
, pp. 47-65
-
-
Venkatesan, K.1
-
166
-
-
0021363165
-
Induction of cytosolic and microsomal epoxide hydrolases by the hypolipidaemic compound nafenopin in the mouse liver
-
Waechter F., Bieri F., Staubli W., and Bentley P. Induction of cytosolic and microsomal epoxide hydrolases by the hypolipidaemic compound nafenopin in the mouse liver. Biochem. Pharmacol. 33 1 (1984) 31-34
-
(1984)
Biochem. Pharmacol.
, vol.33
, Issue.1
, pp. 31-34
-
-
Waechter, F.1
Bieri, F.2
Staubli, W.3
Bentley, P.4
-
167
-
-
0023791757
-
Organ distribution of epoxide hydrolases in cytosolic and microsomal fractions of normal and nafenopin-treated male DBA/2 mice
-
Waechter F., Bentley P., Bieri F., Muakkassah-Kelly S., Staubli W., and Villermain M. Organ distribution of epoxide hydrolases in cytosolic and microsomal fractions of normal and nafenopin-treated male DBA/2 mice. Biochem. Pharmacol. 37 20 (1988) 3897-3903
-
(1988)
Biochem. Pharmacol.
, vol.37
, Issue.20
, pp. 3897-3903
-
-
Waechter, F.1
Bentley, P.2
Bieri, F.3
Muakkassah-Kelly, S.4
Staubli, W.5
Villermain, M.6
-
168
-
-
0020044727
-
Effect of inducers and inhibitors of glucuronidation on the biliary excretion and choleretic action of valproic acid in the rat
-
Watkins J.B., and Klaassen C.D. Effect of inducers and inhibitors of glucuronidation on the biliary excretion and choleretic action of valproic acid in the rat. J. Pharmacol. Exp. Ther. 220 (1982) 305-310
-
(1982)
J. Pharmacol. Exp. Ther.
, vol.220
, pp. 305-310
-
-
Watkins, J.B.1
Klaassen, C.D.2
-
169
-
-
0019943588
-
Induction studies on the functional heterogeneity of rat liver UDP-glucuronosyltransferases
-
Watkins J.B., Gregus Z., Thompson T.N., and Klaassen C.D. Induction studies on the functional heterogeneity of rat liver UDP-glucuronosyltransferases. Toxicol. Appl. Pharmacol. 64 (1982) 439-446
-
(1982)
Toxicol. Appl. Pharmacol.
, vol.64
, pp. 439-446
-
-
Watkins, J.B.1
Gregus, Z.2
Thompson, T.N.3
Klaassen, C.D.4
-
170
-
-
0025688972
-
Role of cytochromes P450 in drug metabolism and hepatoxicity
-
Watkins P.B. Role of cytochromes P450 in drug metabolism and hepatoxicity. Semin. Liver Dis. 10 4 (1990) 235-250
-
(1990)
Semin. Liver Dis.
, vol.10
, Issue.4
, pp. 235-250
-
-
Watkins, P.B.1
-
171
-
-
0025063782
-
The erythromycin breath test as a predictor of cyclosporine blood levels
-
Watkins P.B., Hamilton R.A., Annesley T.M., Ellis C.N., Kolars J.C., and Voorhees J.J. The erythromycin breath test as a predictor of cyclosporine blood levels. Clin. Pharmacol. Ther. 48 (1990) 120-129
-
(1990)
Clin. Pharmacol. Ther.
, vol.48
, pp. 120-129
-
-
Watkins, P.B.1
Hamilton, R.A.2
Annesley, T.M.3
Ellis, C.N.4
Kolars, J.C.5
Voorhees, J.J.6
-
172
-
-
0026732029
-
Comparison of urinary 6-β-cortisol and the erythromycin breath test as measures of hepatic P450IIIA (CYP3A) activity
-
Watkins P.B., Turgeon D.K., Saenger P., Lown K.S., Kolars J.C., Hamilton T., Fishman K., Guzelian P.S., and Voorhees J.J. Comparison of urinary 6-β-cortisol and the erythromycin breath test as measures of hepatic P450IIIA (CYP3A) activity. Clin. Pharmacol. Ther. 52 (1992) 265-273
-
(1992)
Clin. Pharmacol. Ther.
, vol.52
, pp. 265-273
-
-
Watkins, P.B.1
Turgeon, D.K.2
Saenger, P.3
Lown, K.S.4
Kolars, J.C.5
Hamilton, T.6
Fishman, K.7
Guzelian, P.S.8
Voorhees, J.J.9
-
173
-
-
0026512675
-
Phenobarbital induction of cytochrome P-450 gene expression
-
Waxman D.J., and Azaroff L. Phenobarbital induction of cytochrome P-450 gene expression. Biochem. J. 281 (1992) 577-592
-
(1992)
Biochem. J.
, vol.281
, pp. 577-592
-
-
Waxman, D.J.1
Azaroff, L.2
-
174
-
-
0000978314
-
N-acetyltransferase (mammalian liver)
-
Tabor H., and Tabor C.W. (Eds), Academic Press, New York
-
Weber W.W. N-acetyltransferase (mammalian liver). In: Tabor H., and Tabor C.W. (Eds). "Methods in Enzymology" 17B (1971), Academic Press, New York 805-811
-
(1971)
"Methods in Enzymology"
, vol.17 B
, pp. 805-811
-
-
Weber, W.W.1
-
175
-
-
0022975512
-
Rat liver NAD(P)H: quinone reductase. Construction of a quinone reductase cDNA clone and regulation of quinone reductase mRNA by 3-methylcholanthrene and in persistent hepatocyte nodules induced by chemical carcinogens
-
Williams J.B., Lu A.Y., Cameron R.G., and Pickett C.B. Rat liver NAD(P)H: quinone reductase. Construction of a quinone reductase cDNA clone and regulation of quinone reductase mRNA by 3-methylcholanthrene and in persistent hepatocyte nodules induced by chemical carcinogens. J. Biol. Chem. 261 12 (1986) 5524-5528
-
(1986)
J. Biol. Chem.
, vol.261
, Issue.12
, pp. 5524-5528
-
-
Williams, J.B.1
Lu, A.Y.2
Cameron, R.G.3
Pickett, C.B.4
-
176
-
-
0014664072
-
Studies on the activation in vitro of glucuronyltransferase
-
Winsnes A. Studies on the activation in vitro of glucuronyltransferase. Biochim. Biophys. Acta 191 (1969) 279-291
-
(1969)
Biochim. Biophys. Acta
, vol.191
, pp. 279-291
-
-
Winsnes, A.1
-
177
-
-
0017837214
-
Chloramphenicol glucuronyltransferase: Assay, ontogeny, and inducibility
-
Young W.S., and Lietman P.S. Chloramphenicol glucuronyltransferase: Assay, ontogeny, and inducibility. J. Pharmacol. Exp. Ther. 204 (1978) 203-211
-
(1978)
J. Pharmacol. Exp. Ther.
, vol.204
, pp. 203-211
-
-
Young, W.S.1
Lietman, P.S.2
|