Anticonvulsant activity, adverse effects and plasma levels of conventional antiepileptic drugs at different times after single administration

Polish Journal of Pharmacology

Volumn 49, Issue 1, 1997, Pages 69-

  Borowicz, Kinga K ^a   Gqsior, Maciej ^a   Kocki, T ^a   Blaszczak, P ^a   Turski, Waldemar A ^a   Kleinrok, Zdzislcnv ^a   Czuczvar, Stanislaw J ^a  

^a MEDICAL UNIVERSITY OF LUBLIN   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICONVULSIVE AGENT; CARBAMAZEPINE; PHENYTOIN; VALPROIC ACID;

ANIMAL; ARTICLE; BLOOD; ELECTRIC SHOCK; MOUSE; TIME;

ANIMALS; ANTICONVULSANTS; CARBAMAZEPINE; ELECTROSHOCK; MICE; PHENYTOIN; TIME FACTORS; VALPROIC ACID;

EID: 0030622178     PISSN: 12306002     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (4)

1. Borowicz K. K., Ga_sior M., Kleinrok Z., Czuczwar S. J.: The non-competitive AMPA/kainate receptor antagonist, GYKI 524, potentiates the anticonvulsant activity of conventional antiepileptics. Eur. J. Pharmacol., 1995,281,319-326.
2. Borowicz K. K., Gasior M., Kleinrok Z., Czuczwar S. J.: Competitive NMDA-receptor antagonists, LY 235959 and LY 233053, enhance the protective efficacy of various antiepileptic drugs agains maximal electroshock-induced seizures in mice. Epilepsia, 1996, 37, 618-624.
3. Löscher W., Fassbender C.P., Nolting B.: The role of technical, biological and pharmacological factors in the laboratory evaluation of anticonvulsant drugs. II. Maximal electroshock seizure models. Epilepsy Res., 1991,8,79-94.
4. Pietrasiewicz T., Czechowska G., Dziki M., Turski W. A., Kleinrok Z., Czuczwar S. J.: Competitive NMDA antagonists enhance the antielectroshock activity of various antiepileptics. Eur. J. Pharmacol. 1993, 250, 1-7.