The significant role of endothelial-3 in potentiating electrically stimulated contractions in the rat iris sphincter

General Pharmacology

Volumn 28, Issue 3, 1997, Pages 365-369

  Shinkai Goromaru, Michiko ^a   Samejima, Hirohisa ^a   Takayanagi, Issei ^a  

^a TOHO UNIVERSITY   (Japan)

Author keywords

bosentan; electrical stimulation; endothelin; rat iris sphincter; sarafotoxin S6c

Indexed keywords

ATROPINE; BIG ENDOTHELIN 1; BIG ENDOTHELIN 3; BOSENTAN; CARBACHOL; ENDOTHELIN; ENDOTHELIN 1; ENDOTHELIN 3; ENDOTHELIN A RECEPTOR ANTAGONIST; ENDOTHELIN B RECEPTOR AGONIST; ENDOTHELIN B RECEPTOR ANTAGONIST; ENDOTHELIN RECEPTOR; ENDOTHELIN RECEPTOR AGONIST; ENDOTHELIN RECEPTOR ANTAGONIST; RECEPTOR SUBTYPE; SARAFOTOXIN S6C; TETRODOTOXIN; TTA 386; UNCLASSIFIED DRUG; PROTEIN PRECURSOR; SARAFOTOXINS S6; SULFONAMIDE; VIPER VENOM;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DESENSITIZATION; DRUG ANTAGONISM; ELECTROSTIMULATION; ENZYME IMMUNOASSAY; FACILITATION; MALE; NERVOUS TISSUE; NONHUMAN; PRIORITY JOURNAL; RAT; SMOOTH MUSCLE CONTRACTION; SPHINCTER PUPILLAE MUSCLE; ANIMAL; COMPARATIVE STUDY; DRUG EFFECT; IRIS; METABOLISM; MUSCLE CONTRACTION; PHYSIOLOGY; SMOOTH MUSCLE; WISTAR RAT;

ANIMALS; ELECTRIC STIMULATION; ENDOTHELIN-1; ENDOTHELIN-3; ENDOTHELINS; IRIS; MALE; MUSCLE CONTRACTION; MUSCLE, SMOOTH; PROTEIN PRECURSORS; RATS; RATS, WISTAR; RECEPTORS, ENDOTHELIN; SULFONAMIDES; VIPER VENOMS;

EID: 0030615193     PISSN: 03063623     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-3623(96)00291-1     Document Type: Article

References (22)

1. Amber I., Klog Y., Schvartz I., Hazum E. and Sokolovsky M. (1989) Competitive interaction between endothelin and sarafotoxin: binding and phosphoinositides hydrolysis in rat atria and brain. Biochem. Biophys. Res. Commun. 158, 195-201.
2. Arai H., Hori S., Aramori I., Ohkubo H. and Nakanishi S. (1990) Cloning and expression of a cDNA encoding an endothelin receptor. Nature (Lond) 348, 730-732.
3. Bax W. A. and Saxena P. R. (1994) The current endothelin receptor classification: time for reconsideration? Trends Pharmacol. Sci. 15, 379-386.
4. Borges R., Von Grafenstein R. and Knight D. E. (1989) Tissue selectivity of endothelin. Eur. J. Pharmacol. 165, 223-230.
5. Clozel M., Ereu V., Gray G. A., Kalina B., Loffler B.-M., Burri K., Cassal J.-M., Hirth G., Muller M., Neidhart W. and Ramuz H. (1994) Pharmacological characterization of bosentan, a new potent orally active non-peptide endothelin receptor antagonist. J. Pharmacol. Exp. Ther. 270, 228-235.
6. D'Orleans-Juste P., Lidbery P. S., Warner T. D. and Vane J. R. (1990) Intravascular big endothelin increases circulating levels of endothelin and prostanoids in the rabbit. Biochem. Pharmacol. 39, R21-22.
7. Eglen R. M., Michel N. A., Sharif N. A., Swank S. R. and Whiting R. L. (1989) The pharmacological properties of the peptide, endothelin. Br. J. Pharmacol. 97, 1297-1307.
8. Fukuroda T., Noguchi K., Tsuchida S., Nishikibe M., Ikemoto F., Okada K. and Yano M. (1990) Inhibition of biological actions of big endothelin-1 by phosphoramidon. Biochem. Biophys. Res. Commun. 172, 390-395.
9. Geppetti P., Patacchini R., Meini S. and Manzini S. (1989) Contractile effect of endothelin on isolated iris sphincter muscle of the pig. Eur. J. Pharmacol. 168, 119-121.
10. Giad A., Gibson S. J., Ibrahim N. B. M., Legon S., Bloom S. R., Yanagisawa M., Masaki T., Varndell I. M. and Polak J. M. (1989) Endothelin 1, an endothelium-derived peptide, is expressed in neurons of the human spinal cord and dorsal root ganglia. Proc. Natl. Acad. Sci. USA 86, 7634-7638.
11. Granstam E., Wang L. and Bill A. (1990) Effect of endothelin on pupil size and intraocular pressure in the rabbit and the cat. Acta. Physiol. Scand. 140, 5A-C4.
12. Kashiwabara T., Inagaki Y., Ohta H., Iwamatsu A., Nomizu M., Morita A. and Nishikori K. (1989) Putative precursors of endothelin have less vasoconstrictor activity in vitro but a potent pressor effect in vivo. FEBS Lett. 247, 73-76.
13. A receptor distribution. J. Cardiovasc. Pharmacol. 22(suppl. 8), S128-S131.
14. Lawrence E. and Brain S. D. (1993) Big endothelin-1 and big endothelin-3 are constrictor agents in the microvasculature: evidence for the local phosphoramidon-sensitive conversion of big endothelin-1. Eur. J. Pharmacol. 223, 243-250.
15. MacCumber M. W., Ross C. A., Glaser B. M. and Snyder S. H. (1989) Endothelin: visualization of mRNAs by in situ hybridization provides evidence for local action. Proc. Natl. Acad. Sci. USA 86, 7285-7289.
16. Panek R. L., Major T. C., Hingotani G. P., Doherty A. M., Taylor D. G. and Rapundalo S. T. (1992) Endothelin and structurally related analogs distinguish between endothelin receptor subtypes. Biochem. Biophysical. Res. Commun. 183, 566-571.
17. Sakurai T., Yanagisawa M., Takuwa Y., Miyazaki H., Kimura S., Goto K. and Masaki T. (1990) Cloning of a cDNA encoding a non-isopeptide-selective subtype of the endothelin receptor. Nature (Lond) 348, 732-735.
18. Shinkai M., Tsuruoka H., Wakabayashi S., Yamamoto Y. and Takayanagi I. (1994) Pre- and postjunctional actions of endothelin in the rat iris sphincter preparation. Naunyn Schmiedebergs Arch. Pharmacol. 350, 63-67.
19. Uchida Y., Nishinomiya M., Saotome A., Nomura M., Ohtsuka M., Yanagisawa M. and Goto K. (1988) Endothelin, a novel vasoconstrictor peptide, as potent bronchoconstrictor. Eur. J. Pharmacol. 154, 227-232.
20. Warner T. D., Budzik G. P., Matsumoto T., Mitchell J. A. and Murad F. (1992) Regional difference of endothelin converting enzyme activity in rat brain: inhibition by phosphoramidon and EDTA. Br. J. Pharmacol. 106, 948-952.
21. Yanagisawa M., Kurihara M., Kimura S., Tomobe Y., Kobayashi M., Misui Y., Yazaki Y., Goto K. and Masaki T. (1988) A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature (Lond) 332, 411-415.
22. Yoshizawa T., Kimura S., Kanazawa I., Uchiyama Y., Yanagisawa M. and Masaki T. (1989) Endothelin localizes in the dorsal horn and acts on the spinal neurons: possible involvement of dihydropyndine-sensitive calcium channels and substance P release. Neurosci. Lett. 103, 179-184.