Cytochrome P4S0 2E1 polymorphism as a risk factor for lung cancer: In relation to p53 gene mutation

Anticancer Research

Volumn 17, Issue 1 B, 1997, Pages 583-587

  Oyama, Tsunehiro ^a,d   Kawamoto, Toshihiro ^a   Mizoue, Tetsuya ^a   Sugio, Kenji ^b   Kodama, Yasushi ^a   Mitsudomi, Tetsuya ^c   Yasumoto, Kosei ^a  

^a UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

^c AICHI CANCER CENTER HOSPITAL   (Japan)

^d Carbone LAB ^*  (United States)

Author keywords

CYP2E1 polymorphism; Genetic susceptibility; Lung cancer; p53 gene mutation; Prevention

Indexed keywords

CARCINOGEN; CYTOCHROME P450; PROTEIN P53; CYTOCHROME P450 2E1;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; DNA POLYMORPHISM; FEMALE; GENE MUTATION; HUMAN; HUMAN CELL; INCIDENCE; LUNG ADENOCARCINOMA; LUNG NON SMALL CELL CANCER; MAJOR CLINICAL STUDY; MALE; METABOLISM; PRIORITY JOURNAL; RISK FACTOR; SQUAMOUS CELL CARCINOMA; ADENOCARCINOMA; ENZYMOLOGY; GENETIC POLYMORPHISM; GENETICS; GENOTYPE; LUNG TUMOR; MIDDLE AGED; TUMOR SUPPRESSOR GENE;

ADENOCARCINOMA; ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, NON-SMALL-CELL LUNG; CARCINOMA, SQUAMOUS CELL; CYTOCHROME P-450 CYP2E1; FEMALE; GENES, P53; GENOTYPE; HUMANS; LUNG NEOPLASMS; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC; RISK FACTORS;

EID: 0030615114     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Kalo S, Shields PG, Caporaso NE, Hoover RN, Trump BF, Sugimura H, Weston A and Harris CC: Cytochrome P450IIE1 genetic polymorphisms, racial variation, and lung cancer risk. Cancer Res 52: 6712-6715, 1992.
2. Smith CAD, Smith G and Wolf CR: Genomic polymorphisms in xenobiotic metabolism. Eur J Cancer 30A: 1921-1935, 1994.
3. Hirvonen A, Husgatvel-Pursiainen K, Antlila S, Kavjaiainen A and Vainio H: The human CYP2E1 gene and lung cancer: Dra I and Rsa I restriction fragment length polymorphisms in a Finnish study population. Carcinogenesis 14: 85-88, 1993.
4. Uematsu F, Ikawa S, Kikuchi H, Sagami I, Kanamaru R, Abe T, Satoh K, Motomiya M and Watanabe M: Restriction fragment length polymorphism of the human CYP2E1 (cytochrome P450) gene and susceptibility to iung cancer: possible relevance to low smoking exposure. Pharmacogenetics 4: 58-65, 1994.
5. Hayashi S-I, Watanabe J and Kawajiri K: Genetic polymorphisms in 5′-flanking region change transcriptional reguiation of the human cytochrome P450IIE1 gene. J Biochem 110: 559-569, 1991.
6. Uematsu F, Kikuchi H. Motomiya M, Abe T Sagami I Ohmachi T, Wakui A, Kanamaru R and Watanabe M: Association between restriclion fragment length polymorphism of the human cytvchrome P450IIE1 gene and susceptibility to lung cancer. Jpn J Cancer Res 82: 254-256, 1991.
7. Doll R and Peto R: "Causes of cancer." 1981 Oxford University Press. New York.
8. Minna JD: The molecular biology of lung cancer pathogenesis. Chesl 103: 445S-456S, 1993.
9. Minna JD, Pass H, Glatstein E and Ihde DC: Cancer of the lung. In: VT De Vita, 5 Hellman and SA Rosenberg (eds). Cancer: Principles and Practice of Oncology, pp. 591-705 Philadelphia: J. B. Lippincott, 1989.
10. Davis LG, Dibner MD and Battey JF: "Basic methods in molecular biology." 1986 Elsevier. New York.
11. Mitsudomi T, Oyama T, Kusano T, Osaki T, Nakanishi R and Shirakusa T: Mutations of the p53 gene as a predictor of poor prognosis in patients with non-small cell lung cancer. J Natl Cancer Inst 85: 2018-2023, 1993.
12. SAS Institute 'The GLM Procedure." In: SAS/STAT™ User's Guide Release 6.03, pp. 519-548 Cary, NC: SAS Institute, 1988.
13. Tokuhata GK and Lilienfield AM: Familial aggregation of lung cancer in humans. J Natl Cancer Inst 30: 289-312, 1963.
14. Ooi WL, Elston RC, Chen VW, Bailey-Wilson JE and Rothschild H: Increased familial risk for lung cancer. J Natl Cancer Inst 76: 217-222, 1986.
15. Caporaso NG, Tucker MA, Hoover RN, Hayes RB, Pickle LW, Issaq HJ, Muschik GM, Green-Gallo L, Buivys D, Aisner S, Resau JH, Trump BF, Tollerud D, Waston A and Harris CC: Lung cancer and the debrisoquine metabolic phenotype. J Natl Cancer Inst 82: 1268-1272, 1990.
16. Hayashi S-I, Watanabe J and Kawajiri K: High susceptibility to lung cancer analyzed in terms of combined genotypes of P450IA1 and Muclass Glutathione S-Transferase gene. Jpn J Cancer Res 83: 866-870, 1992.
17. Nakachi K, Imai K, Hayashi S-I and Kwajiri K: Polymorphisms of the CYPIA1 and Glutathione S-Transferase genes associated with susceptihility to lung cancer in relation to cigarette dose in a Japanese population. Cancer Res 53: 2994-2999, 1993.
18. Greenblatt MS, Benrtt WP, Hollstein M and Harris CC: Mutations in the p53 tumor suppressor gene; Clues to cancer etiology and molecular pathogenesis. Cancer Res 54: 4855-4878, 1994.
19. Suzuki H, Takashi T, Kuroishi T, Suyama M, Anyoshi Y, Takahashi T and Uedla R: p53 mutations in non-small cell lung cancer in Japan: association between mutations and smoking. Cancer Res 52: 734-736, 1992.