Effects of PGE2 on amount and composition of high molecular weight glycoproteins released by human gastric mucous cells primary culture

Prostaglandins Leukotrienes and Essential Fatty Acids

Volumn 56, Issue 2, 1997, Pages 93-98

  Enss, M L ^a   Wagner, S ^a   Schmidt Wittig, U ^a   Heim, H K ^a   Beil, W ^a   Hedrich, H J ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOPROTEIN; PROSTAGLANDIN E2; 16,16 DIMETHYLPROSTAGLANDIN E2; CARBOHYDRATE; LECTIN; MANNOSE;

ARTICLE; CARBOHYDRATE ANALYSIS; CELL CULTURE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; GLYCOPROTEIN SYNTHESIS; HUMAN; HUMAN CELL; MUCOUS CELL; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN CONTENT; STOMACH MUCUS; CHEMISTRY; DRUG EFFECT; GLYCOSYLATION; MOLECULAR WEIGHT; PROTEIN BINDING; SECRETION; STOMACH MUCOSA;

16,16-DIMETHYLPROSTAGLANDIN E2; CARBOHYDRATES; CELLS, CULTURED; DINOPROSTONE; ENZYME-LINKED IMMUNOSORBENT ASSAY; GASTRIC MUCOSA; GLYCOPROTEINS; GLYCOSYLATION; HUMANS; LECTINS; MANNOSE; MOLECULAR WEIGHT; PROTEIN BINDING;

EID: 0030614955     PISSN: 09523278     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0952-3278(97)90503-2     Document Type: Article

References (29)

1. Strous G. J., Dekker J. Mucin-type glycoproteins. Crit Rev Biochem Mol Biol 1991; 27: 57-92.
2. 2 in gastric mucosa of children with Helicobacter pylon gastritis: relation to thickness of mucus gel layer. J Clin Pathol 1993; 836-839.
3. Carlstedt I., Sheeham J. K., Corfield A. P., Gallagher J. T. Mucous glycoproteins: A gel of a problem. Essays Biochem 1985; 20: 40-76.
4. Forstner G. Signal transduction, packaging and secretion of mucins. Annu Rev Physiol 1995; 57: 585-605.
5. Bansil R., Stanley E., LaMont J. T. Mucin biophysics. Annu Rev Physiol 1995; 57: 635-657.
6. 14C-labelled mucins from rat submandibular salivary acini in vitro. Arch Oral Biol 1987; 32: 719-722.
7. ++-dependent and -independent secretagogues action on gastric mucus secretion in rabbit mucosa explants. Am J Physiol 1989; 256: G739-G746.
8. 3H]L-leucine by isolated pig gastric mucosal cells. Digestion 1989; 44: 26-35.
9. Keates A. C., Hansen P. J. Regulation of mucus secretion by cells isolated from the rat gastric mucosa. J Physiol 1990; 423: 397-409.
10. McCool D. J., Marcon M. A., Forstner J. F., Forstner G. G. T84 human colonic adenocarcinoma cell line produces mucin in culture and releases it in response to various secretagogues. Biochem J 1990; 267: 491-500.
11. Heim H.-K., Sewing K.-F. Pharmacological regulation of gastric mucous glycoprotein secretion. Eur J Gastroenterol Hepatol 1995, in press.
12. Wagner S., Schumann S., Enss M.-L., Beil W., Mai U. E. H., Manns M. Regulation and time course of mucus and prostaglandin secretion in human gastric mucous cells in long-term primary culture. Gastroenterology 1995; 108: A251.
13. Enss M.-L., Grosse-Siestrup H., Schmidt-Wittig U., Gaertner K. Changes in colonic mucins of germfree rats in response to the introduction of a 'normal' rat microbial flora. J Exp Anim Sci 1992; 110-119.
14. 2 alters terminal glycosylation of high molecular weight glycoproteins, released by pig gastric mucous cells in vitro. Prostaglandins Leukot Essent Fatty Acids 1995; 52: 333-340.
15. 2 and carbeneoxolone. Gastroenterology 1981; 80: 770-775.
16. Seidler U., Knafla K, Kownatzki R., Sewing K.-F. Effects of endogenous and exogenous prostaglandins on glycoprotein synthesis and secretion in isolated rabbit gastric mucosa. Gastroenterology 1988; 95: 945-951.
17. Scheiman J. M., Kraus E. R., Boland C. R., Regulation of canine gestric mucin synthesis and phospholipid secretion by acid secretagogues. Gastroenterology 1992; 103: 1642-1650.
18. Terano A., Mach T., Stachura J., Sekhon S., Tarnawski A., Ivay K.J. A monolayer culture of human gastric epithelial cells. Dig Dis Sci 1983; 28: 595-603.
19. Brown J. F., Keates A. C., Hanson P. J., Whittle B.J.R. Nitric oxide generators and cGMP stimulate mucus secretion by rat gastric mucosal cells. Am J Physiol 1993; 265: G418-G422.
20. Raouf A., Parker N., Iddon D. et al. Ion-exchange chromatography of purified colonic mucus glycoproteins in inflammatory bowel disease: absence of a selective subclass defect. Gut 1991; 32: 1139-1145.
21. Kosmala M., Carter S., Konturek S.J., Slomiany A., Slomiany B. L. Mucus glycoprotein secretion by duodenal mucosa in response to luminal arachidonic acid. Biochim Biophys Acta 1986; 884: 419-428.
22. Terano A., Hiraishi H., Ota S., Sugimoto T. Arachidonic acid stimulation of mucus production by rat gastric cultured cells. Dig Dis Sci 1987; 32: 878-882.
23. 2 analogue, on human gastric acid secretion and soluble mucin output. Eur J Clin Invest 1987; 17: 1-6.
24. Rhodes J. M., Black R. R., Savage A. Altered lectin-binding by colonic epithelial glycoconjugates in ulcerative colitis and Crohn's disease. Dig Dis Sci 1988; 33: 1359-1363.
25. Ishikawa N., Horii Y., Nawa Y. Immun-mediated alteration of the terminal sugars of goblet cell mucins in the small intestine of Nippostrongylus brasiliensis-infected rats. Immunology 1991; 78: 303-307.
26. Hanski C., Hanisch F. G., Riecken E. O. Alteration of mucin-bound carbohydrate moieties in malignant transformation of colonic mucosa. Cancer J 1992; 5: 332-342.
27. Van Niew Amerongen A., Oderkerk C. H., Roukema P. A., Wolf J. H., Lisman J.J. W., Vliegenhardt J. F. G. Primary structure of O- and N-glycosydic carbohydrate chains derived from murine submandibular mucin. Carbohydr Res 1987; 64: 43-54.
28. Tse S.-K., Chadee K. The interaction between intestinal mucus glycoproteins and enteric infections. Parasitol Tod 1991; 7: 163-172.
29. Forstner J. F., Forstner G. G. Gastrointestinal mucus. In: Johnson L. R., ed. Physiology of the Gastrointestinal tract, 3rd edn. New York: Raven Press, 1994: 1255-1283.