Binding of the [125I]3β-(iodophenyl)tropan-2β-carboxylic acid isopropyl ester to the dopamine transporter at a physiologically relevant temperature: Mutually exclusive binding and different ionic requirements for various uptake blockers and substrates

Synapse

Volumn 25, Issue 2, 1997, Pages 155-162

  Chen, Nian Hang ^a   Wang, You Lin ^a   Reith, Maarten E A ^b  

^a NANJING MEDICAL UNIVERSITY   (China)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

cocaine; dopamine transporter; ion dependence; rat striatum; RTI 121 binding

Indexed keywords

1 [1 (2 BENZO[B]THIENYL)CYCLOHEXYL]PIPERIDINE; 1 [2 (BENZHYDRYLOXY)ETHYL] 4 (3 PHENYLPROPYL)PIPERAZINE; 3BETA (4 FLUOROPHENYL) 2BETA TROPANECARBOXYLIC ACID METHYL ESTER; 3BETA (4 IODOPHENYL) 2BETA TROPANECARBOXYLIC ACID ISOPROPYL ESTER; AMPHETAMINE; CITALOPRAM; COCAINE; COCAINE DERIVATIVE; DOPAMINE TRANSPORTER; DOPAMINE UPTAKE INHIBITOR; IODINE 125; MAZINDOL; SODIUM CHLORIDE; CARRIER PROTEIN; DRUG DERIVATIVE; MEMBRANE PROTEIN; NERVE PROTEIN; SLC6A3 PROTEIN, RAT;

ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BRAIN SYNAPTOSOME; CONTROLLED STUDY; CORPUS STRIATUM; DOPAMINE UPTAKE; DRUG BINDING SITE; DRUG RECEPTOR BINDING; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR DENSITY; SYNAPTIC MEMBRANE; TEMPERATURE; ANIMAL; BINDING COMPETITION; DOSE RESPONSE; DRUG EFFECT; SPRAGUE DAWLEY RAT; SYNAPTOSOME;

ANIMALS; BINDING, COMPETITIVE; CARRIER PROTEINS; COCAINE; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; MALE; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; NERVE TISSUE PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; SYNAPTOSOMES;

EID: 0030614932     PISSN: 08874476     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2396(199702)25:2<155::AID-SYN6>3.0.CO;2-B     Document Type: Article

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