α2-Adrenoceptor antagonists reverse the 5-HT2 receptor antagonist suppression of head-twitch behavior in mice

Pharmacology Biochemistry and Behavior

Volumn 56, Issue 3, 1997, Pages 417-422

  Matsumoto, Kinzo ^a   Mizowaki, Maho ^a   Thongpraditchote, Suchitra ^a   Murakami, Yukihisa ^a   Watanabe, Hiroshi ^a  

^a UNIVERSITY OF TOYAMA   (Japan)

Author keywords

2 adrenoceptor; 5 HT2 receptor; head twitch behavior; mice; noradrenaline

Indexed keywords

5 METHOXY N,N DIMETHYLTRYPTAMINE; ALPHA 2 ADRENERGIC RECEPTOR; ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT; CLONIDINE; FENCLONINE; IDAZOXAN; KETANSERIN; NOMIFENSINE; NORADRENALIN; OXIDOPAMINE; PRAZOSIN; RITANSERIN; SEROTONIN; SEROTONIN 2 RECEPTOR; SEROTONIN ANTAGONIST; YOHIMBINE; ALPHA ADRENERGIC RECEPTOR STIMULATING AGENT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN INJURY; CONTROLLED STUDY; HEAD TWITCH; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; MOUSE; NONHUMAN; NORADRENERGIC SYSTEM; PRIORITY JOURNAL; SEROTONINERGIC SYSTEM; ANIMAL; DRUG ANTAGONISM; DRUG EFFECT; DRUG SCREENING; HEAD MOVEMENT; MOUSE STRAIN; PHYSIOLOGY;

ADRENERGIC ALPHA-AGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANIMALS; CLONIDINE; DRUG EVALUATION, PRECLINICAL; FENCLONINE; HEAD MOVEMENTS; KETANSERIN; MALE; MICE; MICE, INBRED STRAINS; NOREPINEPHRINE; OXIDOPAMINE; RECEPTORS, ADRENERGIC, ALPHA-2; RITANSERIN; SEROTONIN; SEROTONIN ANTAGONISTS;

EID: 0030614808     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0091-3057(96)00223-7     Document Type: Article

References (24)

1. 2 receptor subtypes: A family re-united?; TIPS 16:105-110; 1995.
2. Bednarczyk, B.; Vetulani, J. Antagonism of clonidine to shaking behavior in morphine abstinence syndrome and to head twitches produced by serotonergic agents in the rat. Pol. J. Pharmacol. Pharm. 30:307-322; 1978.
3. Corne, S. J.; Pickering, R. W.; Warner, B. T. A method for assessing the effects of drugs on the central actions of 5-hydroxytryptamine. Br. J. Pharmacol. 20:106-120; 1963.
4. 2 receptors: Microdialysis studies in the awake and anaesthetized rat. Neuropharmacology 33:411-421; 1994.
5. 1A receptor agonists in the mouse. Br. J. Pharmacol. 109:1046-1052; 1993.
6. Frankhuijzen, A. L.; Wardeh, G.; Hogenboom, F.; Mulder, A. H. α2-Adrenoceptor mediated inhibition of release of radiolabelled 5-hydroxytryptamine and noradrenaline from slices of the dorsal region of the brain. Naunyn-Schmied. Arch. Pharmacol. 337:255-260; 1988.
7. 2 agonists or antagonists? Neuropsychopharmacology 3:509-517; 1990.
8. 2 involvement in the mechanism of action of hallucinogenic agents. Life Sci. 35:2505-2511; 1984.
9. 3H]5-hydroxytryptamine release from rat brain cortex synaptosomes. J. Pharm. Pharmacol. 45:811-814; 1993.
10. Green, A. R.; Heal, D. A. The effects of drugs on serotonin-mediated behavioural models. Neuropharmacology of Serotonin. A. R. Green, ed. Oxford: Oxford University Press;1985: 326-363.
11. 2 antagonist pirenperone. Neuropharmacology 22:573-578; 1983.
12. Haley, T. J.; McCormick, W. G. Pharmacological effects produced by intracerebral injection of drugs in the conscious mouse. Br. J. Pharmacol. 12:12-15; 1957.
13. Handley, S. L.; Brown, J. Effects on the 5-hydroxytryptamine-induced head-twitch of drugs with selective actions on alphal and alphα2-adrenoceptors. Neuropharmacology 21:507-510; 1982.
14. Handley, S. L.; Singh, L. Involvement of the locus coeruleus in the potentiation of the quipazine-induced head-twitch response by diazepam and beta-adrenoceptor agonists. Neuropharmacology 25:1315-1321; 1986.
15. Handley, S. L.; Singh, L. The modulation of head-twitch behaviour by drugs acting on beta-adrenoceptors: Evidence for the involvement of both betal- and betα2-adrenoceptors. Psychopharmacology 88:320-324; 1986.
16. 2-mediated head-twitch responses in mice: Possible implications for the actions of antidepressant drugs. Psychopharmacology 89:414-420; 1986.
17. 2 receptor binding sites. Mol. Pharmacol. 21:301-314; 1982.
18. Malick, J. B.; Doren, E.; Barnett, A. Quipazine-induced head-twitch in mice. Pharmacol. Biochem. Behav. 6:325-329; 1977.
19. Numazawa, R.; Yoshioka, M.; Matsumoto, M.; Togashi, H.; Kemmotsu, O.; Saito, H. Pharmacological characterization of α2-adrenoceptor regulated serotonin release in the rat hippocampus. Neurosci. Lett. 192:161-164; 1995.
20. Ojima, K.; Matsumoto, K.; Tohda, M.; Watanabe, H. Hyperactivity of central noradrenergic and CRF systems is involved in social isolation-induced decrease in pentobarbital sleep. Brain Res. 684:87-94; 1995.
21. Orikasa, S.; Sloley, B. D. Effects of 5,7-dihydroxytryptamine and 6-hydroxydopamine on head-twitch response induced by serotonin, p-chloroamphetamine, and tryptamine in mice. Psychopharmacology 95:124-131; 1988.
22. Ortmann, R.; Bischoff, S.; Radeke, E.; Buech, O.; Delini-Stula, A. Corrlations between different measures of antiserotonin activity of drugs: Study with neuroleptics and serotonin receptor blockers. Naunyn-Schmied. Arch. Pharmacol. 321:265-270; 1982.
23. Peroutka, S. J.; Lebovitz, R. M.; Snyder, S. H. Two distinct central serotonin receptors with different physiological functions. Science 212:827-829; 1981.
24. 2A receptors in antipsychotic activity. Life Sci 56:2209-2222; 1995.