Leukotriene D4-induced Ca2+ mobilization in Ehrlich ascites tumor cells

Journal of Membrane Biology

Volumn 155, Issue 1, 1997, Pages 61-73

  Pedersen, S ^a   Hoffmann, E K ^a   Hougaard, C ^a   Jorgensen N K ^a   Wybrandt, G B ^a   Lambert, I H ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Ca2+ mobilization; Ins(1,4,5)P3; Leukotriene D4 receptor; Phospholipase C; Thapsigargin; U73122

Indexed keywords

1 [2 (4 METHOXYPHENYL) 2 [3 (4 METHOXYPHENYL)PROPOXY]ETHYL] 1H IMIDAZOLE; 1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; CALCIUM CHANNEL; GADOLINIUM; LEUKOTRIENE B4; LEUKOTRIENE C4; LEUKOTRIENE D4; LEUKOTRIENE RECEPTOR; PHOSPHOLIPASE C; THAPSIGARGIN; VERAPAMIL; 1 (6 ((3 METHOXYESTRA 1,3,5(10) TRIEN 17 YL)AMINO)HEXYL) 1H PYRROLE 2,5 DIONE; 1-(6-((3-METHOXYESTRA-1,3,5(10)-TRIEN-17-YL)AMINO)HEXYL)-1H-PYRROLE-2,5-DIONE; 2 PYRROLIDONE DERIVATIVE; CALCIUM; CYSTEINYL LEUKOTRIENE RECEPTOR 2; ENZYME INHIBITOR; ESTRANE DERIVATIVE; FLUORESCENT DYE; FURA 2; INOSITOL 1,4,5 TRISPHOSPHATE; LEUKOTRIENE D4 RECEPTOR; LEUKOTRIENE RECEPTOR BLOCKING AGENT; MEMBRANE PROTEIN;

ANIMAL CELL; ARTICLE; CALCIUM MOBILIZATION; CALCIUM TRANSPORT; CONTROLLED STUDY; DRUG EFFECT; EHRLICH ASCITES TUMOR CELL; MOUSE; NONHUMAN; ANIMAL; CELL CULTURE; DRUG ANTAGONISM; EHRLICH ASCITES TUMOR; METABOLISM;

ANIMALS; CALCIUM; CALCIUM CHANNELS; CARCINOMA, EHRLICH TUMOR; ENZYME INHIBITORS; ESTRENES; FLUORESCENT DYES; FURA-2; INOSITOL 1,4,5-TRISPHOSPHATE; LEUKOTRIENE ANTAGONISTS; LEUKOTRIENE D4; MEMBRANE PROTEINS; MICE; PHOSPHOLIPASE C; PYRROLIDINONES; RECEPTORS, LEUKOTRIENE; TUMOR CELLS, CULTURED;

EID: 0030614571     PISSN: 00222631     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002329900158     Document Type: Article

References (48)

1. Badr, K.F., Mong, S., Hoover, R.L., Schwartzberg, M., Eben, J., Jacobson, H.R., Harris, R.C. 1989. Am. J. Physiol. 257:F280-F287
2. 4 of increases in cytosolic concentration of calcium in dimethylsulfoxide-differentiated HL-60 cells. J. Clin. Invest. 80:983-991
3. Bennett, V. 1985. The membrane skeleton of human erythrocytes and its implications for more complex cells. Annu. Rev. Biochem. 54:273-304
4. Berridge, M.J. 1993. Inositol trisphosphate and calcium signalling. Nature 361:315-325
5. 2+ inflow. Biochem. Pharmacol. 49:1373-1379
6. Brain, S.D., Williams, T.J. 1990. Leukotrienes and inflammation. Pharmac. Ther. 46:57-66
7. 4 receptor antagonists. J. Pharmacol. Exp. Ther. 269:891-896
8. - channels as well as a nonselective, stretch-activated cation channels in Ehrlich ascites tumors cells. J. Membrane Biol. 129:13-36
9. Clapham, D.E. 1995. Replenishing the stores. Nature 375:634-635
10. 4 receptor. Trends Pharm. Sci. 10:103-107
11. Dean, N.M., Beaven, M.A. 1989. Methods for the analysis of inositol phosphates. Anal. Biochem. 183:199-209
12. s function. FEBS lett. 357:13-15
13. Franzius, D., Hoth, M., Penner, R. 1994. Nonspecific effects of calcium entry antagonists in mast cells. Eur. J. Physiol. 428:433-438
14. 2+ pool is sensitive to both inositol 1,4,5-triphosphate and thapsigargin. Cell Calcium 17:431-441
15. Gardiner, P.J., Abram, T.S., Cuthbert, N.J. 1990. Evidence for two leukotriene receptor types in guinea-pig isolated ileum. Eur. J. Pharmacol. 182:291-299
16. β blocker, via multiple mechanisms. Br. J. Pharmacol. 115:11-14
17. 4-induced calcium influx in human epithelial cells involves protein tyrosine phosphorylation. Cell Calcium 17:177-186
18. 2+ indicators with greatly improved fluorescence properties. J. Biol. Chem. 260:3440-3450
19. Hay, D.W.P., Torphy, R.J., Undem, B.J. 1995. Cysteinyl leukotrienes in asthma: Old mediators up to new tricks. TIPS 16:304-309
20. Hoffmann, E.K., Dunham, P. 1995. Membrane mechanisms and intracellular signaling in cell volume regulation. Intern. Rev. Cyt. 161:173-262
21. - transport pathways in Ehrlich ascites tumor cells. J. Membrane Biol. 91:227-244
22. Holtzman, M.J. 1992. Arachidonic acid metabolism in airway epithelial cells. Annu. Rev. Physiol. 54:303-329
23. 4 involve a pertussis toxin sensitive G-protein. Eur. J. Pharmacol. 227:123-129
24. 4 in the regulatory volume decrease response in Ehrlich ascites tumors cells. J. Membrane Biol. 151:159-173
25. Lambert, I.H. 1987. Effect of arachidonic acid, fatty acids, prostaglandins, and leukotrienes on volume regulation in Ehrlich ascites tumor cells. J. Membrane Biol. 98:207-221
26. 4 induced cell shrinkage in Ehrlich ascites tumor cells. J. Membrane Biol. 108: 165-176
27. Lambert, I.H. 1994. Eicosanoids and cell volume regulation. In: Cellular and molecular physiology of cell volume regulation pp. 279-298. CRC Press, Boca Raton, FL
28. Lambert, I.H., Hoffmann, E.K. 1993. Regulation of taurine transport in Ehrlich ascites tumor cells. J. Membrane Biol. 131:67-79
29. Lambert, I.H., Hoffmann, E.K., Christensen, P. 1987. Role of prostaglandins and leukotrienes in volume regulation by Ehrlich ascites tumor cells. J. Membrane Biol. 98:247-256
30. Merritt, J.E., Armstrong, W.P., Benham, C.D., Hallam, T.J., Jacob, R., Jaxa-Chamiec, A., Leigh, B.K., McCarthy, S., Moores, K.E., Rink, T.J. 1990. SK&F 96365, a novel inhibitor of receptor-mediated calcium entry. Biochem. J. 271:515-522
31. Merritt, J.E., Armstrong, W.P., Hallam, T.J., Jaxa-Chamiec, A., Leigh, B.K., Moores, K.E., Rink, T.J. 1989. SK&F 96365, a novel inhibitor of receptor-mediated calcium entry and aggregation in Quin2-loaded human platelets. Br. J. Pharmacol. 98:674P
32. 4 receptors. Molecular Pharmacol. 31:35-41
33. 4 receptor-mediated hydrolysis of phosphoinositide and mobilization of calcium in sheep tracheal smooth muscle cells. J. Pharmacol. Exp. Ther. 244:508-515
34. Nicosia, S., Patrono, C. 1989. Eicosanoid biosynthesis and action: Novel opportunities for pharmacological intervention. FASEB J. 3:1941-1948
35. 4 receptor in Ehrlich Ascites Tumour Cells. Acta Physiol. Scand. 155:22A
36. 4 receptor in the human THP-1 cell line. Biochim. Biophys. Acta 1177:283-290
37. Samuelsson, B., Dahlén, S., Lindgren, J.Å., Rouzer, C.A., Serhan, C.N. 1987. Leukotrienes and lipoxins: structures, biosynthesis, and biological effects. Science 237:1171-1176
38. 4 receptors and signal transduction processes in rat basophilic leukemia cells. J. Biol. Chem. 262:4034-4041
39. 4 partial agonist activity at leukotriene D4 receptors in differentiated U-937 cells. J. Biol. Chem. 33: 19845-19855
40. 2+-ATPase. Biochim. Biophys. Acta 772:29-36
41. Serhan, C.N. 1991. Lipoxins: Eicosanoids carrying intra- and intercellular messages. J. Bioenergetics and Biomembranes 23:105-122
42. 32P incorporation into phosphorylated metabolites in cultured cells. Anal. Biochem. 124:421-424
43. Simonsen, L.O., Brown, A.M., Christensen, S., Harbak, H., Svane, P.C., Hoffmann, E.K. 1990. Thrombin and bradykinin mimic the volume response induced by cell swelling in Ehrlich mouse ascites tumor cells. Renal Physiol. Biochem. 13:176
44. 4-induced signal transduction. In: Cellular generation, transport, and effects of eicosanoids. Ann. New York Acad. Sci. 744:155-160
45. 4 induce transmembrane signalling in human epithelial cells. J. Biol. Chem. 34:20976-20981
46. Smith, R.J., Sam, L.M., Justen, J.M., Bundy, G.L., Bala, G.A., Bleasdale, J.E. 1990. Receptor-coupled signal transduction in human polymorphonuclear neutrophils: Effects of a novel inhibitor of phospholipase C-dependent processes on cell responsiveness. J. Pharmacol. Exp. Ther. 253:688-697
47. 4 receptor heterogenity. J. Pharmacol Exp. Ther. 249:805-811
48. 2+-ATPase. Proc. Natl. Acad. Sci. 87:2466-2470