Identification of A(2a) adenosine receptor domains involved in selective coupling to Gs: Analysis of chimeric A1/A(2a) adenosine receptors

Journal of Biological Chemistry

Volumn 272, Issue 1, 1997, Pages 337-344

  Olah, Mark E ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE A2 RECEPTOR; ADENOSINE DERIVATIVE; ADENYLATE CYCLASE; GUANINE NUCLEOTIDE BINDING PROTEIN; RECEPTOR SUBTYPE; ADENOSINE RECEPTOR; HYBRID PROTEIN; LIGAND; STIMULATORY GUANINE NUCLEOTIDE BINDING PROTEIN;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CHIMERA; CHO CELL; ENZYME ACTIVITY; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; ANIMAL; BINDING SITE; CHEMISTRY; CYTOPLASM; DOG; HUMAN; METABOLISM; MOLECULAR GENETICS; SEQUENCE ALIGNMENT; STRUCTURE ACTIVITY RELATION;

ANIMALIA; CRICETINAE; CRICETULUS GRISEUS;

ADENYLATE CYCLASE; AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CYTOPLASM; DOGS; GTP-BINDING PROTEIN ALPHA SUBUNITS, GS; HUMANS; LIGANDS; MOLECULAR SEQUENCE DATA; RECEPTORS, PURINERGIC P1; RECOMBINANT FUSION PROTEINS; SEQUENCE ALIGNMENT; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0030614454     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.1.337     Document Type: Article

References (58)

1. Olsson, R. A., and Pearson, J. D. (1990) Physiol. Rev. 70, 761-845
2. Olah, M. E.. and Stiles, G. L. (1992) Annu. Rev. Physiol. 54, 211-225
3. Downey, J. M., Cohen, M. V., Ytrehus, K., and Liu, Y. (1994) Ann. N. Y. Acad. Sci. 723, 82-98
4. Rudolphi, K. A., Schuber, P., Parkinson, F. E., and Fredholm, B. B. (1992) Trends Pharmacol. Sci. 13, 439-445
5. Olah, M. E., and Stiles, G. L. (1995) Annu. Rev. Pharmacol. Toxicol. 35, 581-606
6. Tucker, A. L., and Linden, J. (1993) Cardiovasc. Res. 27, 62-67
7. Munshi R., Pang, I.-H., Sternweis, P. C., and Linden, J. (1991) J. Biol. Chem. 266, 22285-22289
8. Jockers, R., Linder, M. E., Hohenegger, M., Nanoff, C., Bertin, B., Strosberg, A. D., Marullo, S., and Freissmuth, M. (1994) J. Biol. Chem. 269, 32077-32084
9. Zhou, Q.-Y., Li, C., Olah, M. E., Johnson, R. A., Stiles, G. L., and Civelli, O. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 7432-7436
10. Palmer, T. M., Gettys, T. W., and Stiles, G. L (1995) J. Biol. Chem. 270, 16895-16902
11. Ramkumar, V., Stiles, G. L., Beaven, M. A., and Ali, H. (1993) J. Biol. Chem. 268, 16887-16890
12. Gushing, D. J., Brown, G. L., Sabouni, M. H., and Mustafa, S. J. (1991) Am. J. Physiol. 261, H343-H348
13. Kleppisch, T., and Nelson, M. T. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 12441-12445
14. Zhang, Y., and Wells, J. N. (1990) J. Pharmacol. Exp. Ther. 254, 270-276
15. Bullough, D. A., Magill, M. J., Firestein, G. S., and Mullane, K. M. (1995) J. Immunol. 155, 2579-2586
16. Mullane, K., and Bullough, D. (1995) J. Mol. Cell. Cardiol. 27, 1041-1054
17. Taylor, J. M., Jacob-Mosier, G. G., Lawton, R. G., VanDort, M., and Neubig, R. R. (1996) J. Biol. Chem. 271, 3336-3339
18. Strader, C. D., Dixon, R. A. F., Cheung, A. H., Candelore, M. R., Blake, A. D., and Sigal, I. S. (1987) J. Biol. Chem. 262, 16439-16443
19. O'Dowd, B. F., Hnatowich, M., Regan, J. W., Leader, W. M., Caron, M. G., and Lefkowitz, R. J. (1988) J. Biol. Chem. 263, 15985-15992
20. Liggett, S. B., Caron, M. G., Lefkowitz, R. J., and Hnatowich, M. (1991) J. Biol. Chem. 266, 4816-4821
21. Cheung, A. H., Huang, R.-R. C., and Strader, C. D. (1992) Mol. Pharmacol. 41, 1061-1065
22. Cotecchia, S., Exum, S., Caron, M. G., and Lefkowitz, R. J. (1990) Proc. Natl. Acad. Sci. U. S. A. 87, 2896-2900
23. Cotecchia, S., Ostrowski, J., Kjelsberg, M. A., Caron, M. G., and Lefkowitz, R. J. (1992) J. Biol. Chem. 267, 1633-1639
24. Eason, M. G., and Liggett, S. B. (1995) J. Biol. Chem. 270, 24753-24760
25. Wong, S. K.-F., Parker, E. M., and Ross, E. M. (1990) J. Biol. Chem. 265, 6219-6224
26. Lechleiter, J., Hellmiss, R., Duerson, K., Ennulat, D., David, N., Clapham, D., and Peralta, E. (1990) EMBO J. 13, 4381-4390
27. Wess, J., Bonner, T. I., Dörje, F., and Brann, M. R. (1990) Mol. Pharmacol. 38, 517-523
28. Blüml, K., Mutschler, E., and Wess, J. (1994) J. Biol. Chem. 269, 402-405
29. Wong, S. K.-F., and Ross, E. M. (1994) J. Biol. Chem. 269, 18968-18976
30. Hill-Eubanks, D., Burstein, E. S., Spalding, T. A., Bräuner-Osborne, H., and Brann, M. R. (1996) J. Biol. Chem. 271, 3058-3065
31. Dalman, H. M., and Neubig, R. R. (1991) J. Biol. Chem. 266, 11025-11029
32. Okamoto, T., and Nishimoto, I. (1992) J. Biol. Chem. 267, 8342-8346
33. Malek, D., Munch, G., and Palm, D. (1993) FEBS Lett. 325, 215-219
34. McClue, S. J., Baron, B. M., and Harris, B. A. (1994) Eur. J. Pharmacol. 267, 185-193
35. Moro, O., Lameh, J., Högger, P., and Sadée, W. (1993) J. Biol. Chem. 268, 22273-22276
36. Nussenzveig, D. R., Thaw, C. N., and Gershengorn, M. C. (1994) J. Biol. Chem. 269, 28123-28129
37. Hunyady, L., Bor, M., Balla, T., and Catt, K. J. (1995) J. Biol. Chem. 270, 9702-9705
38. Negishi, M., Irie, A., Sugimoto, Y., Namba, T., and Ichikawa, A. (1995) J. Biol. Chem. 270, 16122-16127
39. Palmer, T. M., Poucher, S. M., Jacobson, K. A., and Stiles, G. L. (1995) Mol. Pharmacol. 48, 970-974
40. Maenhaut, C., Van Sande, J., Libert, F., Abramowicz, M., Parmentier, M., Vanderhaegen, J.-J., Dumont, J. E., Vassart, G., and Schiffmann, S. (1990) Biochem. Biophys. Res. Commun. 173, 1169-1178
41. Townsend-Nicholson, A., and Shine, J. (1992) Mol. Brain Res. 16, 365-370
42. Olah, M. E., Jacobson, K. A., and Stiles, G. L. (1994) J. Biol. Chem. 269, 24692-24698
43. Maniatis, T., Fritsch, E. F., and Sambrook, J. (1989) Molecular Cloning: A Laboratory Manual, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
44. Salomon, Y., Londos, C., and Rodbell, M. (1974) Anal. Biochem. 58, 541-548
45. Olah, M. E., Gallo-Rodriguez, C., Jacobson, K. A., and Stiles, G. L. (1994) Mol. Pharmacol. 45, 978-982
46. Bradford, M. M. (1976) Anal. Biochem. 72, 248-254
47. DeLean, A., Hancock, A. A., and Lefkowitz, R. J. (1982) Mol. Pharmacol, 21, 5-16
48. Whaley, B. S., Yuan, N., Birnbaumer, L., Clark, R. B., and Barber, R. (1994) Mol. Pharmacol. 45, 481-489
49. MacEwan, D. J., Kim, G. D., and Milligan, G. (1995) Mol. Pharmacol. 48, 316-325
50. Vogel, W. K., Mosser, V. A., Bulseco, D. A., and Schimerlik, M. I. (1995) J. Biol. Chem. 270, 15485-15493
51. Barrington, W. W., Jacobson, K. A., Hutchison, A. J., Williams, M., and Stiles, G. L. (1989) Proc. Natl. Acad. Sci. U. S. A. 86, 6572-6576
52. Nanoff, C., Jacobson, K. A., and Stiles, G. L. (1991) Mol. Pharmacol. 39, 130-135
53. Palmer, T. M., Benovic, J. L., and Stiles, G. L. (1996) J. Biol. Chem. 271, 15272-15278
54. Namba, T., Sugimoto, Y., Negishi, M., Irie, A., Ushikubi, F., Kakizuka, A., Ito, S., Ichikawa, A., and Narumiya, S. (1993) Nature 365, 166-170
55. Takagi, Y., Ninomiya, H., Sakamoto, A., Miwa, S., and Masaki, T. (1995) J. Biol. Chem. 270, 10072-10078
56. Liu, J., and Wess, J. (1996) J. Biol. Chem. 271, 8772-8778
57. Burstein, E. S., Spalding, T. A., and Brann, M. R. (1996) J. Biol. Chem. 271, 2882-2885
58. Högger, P., Shockley, M. S., Lameh, J., and Sadée, W. (1995) J. Biol. Chem. 270, 7405-7410