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Volumn 20, Issue 1, 1997, Pages 61-65
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β-adrenoceptor antagonistic actions and mutagenicities of R(+)- and S(- )-enantiomers of N-desisopropylpropranolol and its N-acetyl conjugate
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Author keywords
chiral metabolite; enantiospecificity; mutagenicity; N acetyl conjugation; propranolol; adrenoceptor antagonistic action
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Indexed keywords
1 AMINO 3 (1 NAPHTHYLOXY) 2 PROPANOL;
BETA ADRENERGIC RECEPTOR BLOCKING AGENT;
DEISOPROPYLPROPRANOLOL;
ISOPRENALINE;
PROPRANOLOL;
UNCLASSIFIED DRUG;
DRUG DERIVATIVE;
MUTAGENIC AGENT;
N-DESISOPROPYLPROPRANOLOL;
PROPANOLAMINE DERIVATIVE;
ADRENERGIC RECEPTOR BLOCKING;
AMES TEST;
ARTICLE;
CHIRALITY;
CHRONOTROPISM;
DRUG CONJUGATION;
ENANTIOMER;
GUINEA PIG;
HEART ATRIUM;
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;
INOTROPISM;
MUTAGENESIS;
TRACHEA;
ANIMAL;
IN VITRO STUDY;
MALE;
RAT;
STEREOISOMERISM;
WISTAR RAT;
ADRENERGIC BETA-ANTAGONISTS;
ANIMALS;
GUINEA PIGS;
MALE;
MUTAGENS;
PROPANOLAMINES;
PROPRANOLOL;
RATS;
RATS, WISTAR;
STEREOISOMERISM;
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EID: 0030614398
PISSN: 09186158
EISSN: None
Source Type: Journal
DOI: 10.1248/bpb.20.61 Document Type: Article |
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Times cited : (5)
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References (7)
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