The EDB test - A clinical test for the detection of antibodies to botulinum toxin type A

Movement Disorders

Volumn 12, Issue 1, 1997, Pages 95-99

  Kessler, Kirn R ^a   Benecke, Reiner ^a,b  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b UNIVERSITY OF ROSTOCK   (Germany)

Author keywords

Antibodies; Botulinum toxin A; Cervical dystonia; Electrical nerve stimulation; Electromyography

Indexed keywords

ANTIBODY; BOTULINUM TOXIN A; NEUROTOXIN;

ADULT; ANTIBODY BLOOD LEVEL; ANTIBODY DETECTION; ARTICLE; BIOASSAY; CONTROLLED STUDY; DYSTONIA; EXTENSOR MUSCLE; FEMALE; HUMAN; IMMUNOASSAY; INTRAMUSCULAR DRUG ADMINISTRATION; MAJOR CLINICAL STUDY; MALE; MOUSE; MUSCLE ACTION POTENTIAL; NONHUMAN; PERONEUS NERVE; PRIORITY JOURNAL; ANIMAL; BLOOD; COHORT ANALYSIS; DRUG EFFECT; ELECTROMYOGRAPHY; IMMUNOLOGY; TORTICOLLIS; TREATMENT OUTCOME;

ANIMALS; ANTIBODIES; BIOLOGICAL ASSAY; BOTULINUM TOXIN TYPE A; COHORT STUDIES; ELECTROMYOGRAPHY; HUMANS; INJECTIONS, INTRAMUSCULAR; MICE; TORTICOLLIS; TREATMENT OUTCOME;

EID: 0030614321     PISSN: 08853185     EISSN: None     Source Type: Journal    
DOI: 10.1002/mds.870120116     Document Type: Article

References (13)

1. Fiock MA, Cordella MA, Gearinger NF. Studies on immunity to toxins of Clostridium botulinum. IX. Immunologic response of man to purified pentavalent ABCDE botulinum toxoid. J Immunol 1963;90:697-702.
2. Greene P, Fahn S, Diamond B. Development of resistance to botulinum toxin type A in patients with torticollis. Mov Disord 1994;9(2):213-217.
3. Greene PE, Fahn S. Use of botulinum toxin F injections to treat torticollis in patients with immunity to botulinum toxin type A. Mov Disord 1993;8(4):479-183.
4. Hatheway CL, Dang C. Immunogenicity of the neurotoxins of Clostridium botulinum. In: Jankovic J, Hallett M, ed. Therapy with botulinum toxin. New York: Marcel Dekker, 1994:93-107.
5. Zuber M, Sebald M, Bathien N, de Recondo J, Rondot P. Botulinum antibodies in dystonic patients treated with type A botulinum toxin: frequency and significance. Neurology 1993;43:1715-1718.
6. Hamjian JA, Walker FO. Serial neurophysiological studies of intramuscular botulinum-A toxin in humans. Muscle Nerve 1994;17:1385-1392.
7. Kessler KR, Benecke R. Long-term treatment of cervical dystonia with botulinum toxin A: a study of 200 patients. Mov Disord 1994;9(suppl 1):26.
8. Tsui JK, Eisen A, Stoessel AJ, Calne S, Calne DB. Double-blind study of botulinum toxin in spasmodic torticollis. Lancet 1986;2:245-247.
9. Hambleton P, Cohen HE, Palmer BJ, Melling J. Antitoxin and botulinum toxin treatment. Br Med J 1992;304:959-960.
10. Borodic GE, Pearce B, Duane DD, Johnson E. Antibodies to botulinum toxin [Letter]. Neurology 1995;45:204.
11. Gelb DJ, Yoshimura DM, Olney RK, et al. Change in pattern of muscle activity following botulinum toxin injections for torticollis. Ann Neurol 1991;29:370-376.
12. Poewe W, Wissel J. Experience with botulinum toxin in cervical dystonia. In: Jankovic J, Hallett M, eds. Therapy with botulinum toxin. New York: Dekker, 1994:267-278.
13. 125I-Iabelled botulinum neurotoxins with nerve terminals. I. Ultrastructural autoradiographic localization and quantification of distinct membrane acceptors for types A and B on motor nerves. J Cell Biol 1986;103:521-533.