CD4+ T lymphocytes contribute to protective immunity induced in sheep and goats by Haemonchus contortus gut antigens

Parasite Immunology

Volumn 19, Issue 10, 1997, Pages 435-445

  Karanu, Francis N ^a,b   McGuire, Travis C ^a   Davis, William C ^a   Besser, Thomas E ^a   Jasmer, Douglas P ^a  

^a WASHINGTON STATE UNIVERSITY   (United States)

^b KENYA AGRICULTURAL RESEARCH INSTITUTE   (Kenya)

Author keywords

CD4+ T lymphocytes; Gut antigens; Haemonchus contortus; Immunity; Nematode

Indexed keywords

CD4 ANTIGEN; PARASITE ANTIGEN; VACCINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY BLOOD LEVEL; ARTICLE; CELLULAR IMMUNITY; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; GOAT; HAEMONCHUS CONTORTUS; IMMUNIZATION; NONHUMAN; PRIORITY JOURNAL; SHEEP; T LYMPHOCYTE; ANIMAL; CD4+ T LYMPHOCYTE; HAEMONCHUS; IMMUNITY; IMMUNOLOGY; LYMPHOCYTE DEPLETION;

ANIMALS; ANTIGENS, CD4; ANTIGENS, HELMINTH; CD4-POSITIVE T-LYMPHOCYTES; GOATS; HAEMONCHUS; IMMUNITY; LYMPHOCYTE DEPLETION; SHEEP;

EID: 0030613789     PISSN: 01419838     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-3024.1997.d01-149.x     Document Type: Article

References (41)

1. Afonso L.C.C., Scharton T.M., Vieira L.Q., Wysocka M., Trinchieri G. & Scoll P. (1994) The adjuvant effect of lnterleukin-12 in a vaccine against Leishmania major. Science 263, 236-237
2. Andrews S.J., Hole N.J.K., Munn E.A. & Rolph T.P. (1995) Vaccination of sheep against haemonchosis with HI I, a gut membraneassociated protective antigen from the adult parasite: Prevention of periparturient rise and colostral transfer of protective immunity. International Journal for Parasitology 25, H39-846
3. Davis W.C., Marusic S., Lewin H.A., Splitter G.A., Perryman L.A., McGuire T.C. & Gorham J.R. (1987) The development and analysis of specific and cross reactive monoclonal antibodies to leukocytes differentiation antigens and antigens of the major histocompatibility complex for use in the study of the immune system in cattle and other species. Veterinary Immunology and Immunopathology 15, 337-376
4. Davis W.C., MacHugh N.D., Park Y.H., Hamilton M.J. & Wyatt C.R. (1993) Identification of a monoclonal antibody reactive with the bovine orthologue of CD3 (BoCD3). Veterinary Immunology and Immunopathology 39, 85-91
5. Davis W.C., Brown W.C., Hamilton M.J., Wyalt C.R., Orden J.A., Khalid A.M. & Naessens J. (1996) Analysis of monoclonal antibodies specific for the γδ TcR. Veterinary Immunology and Immunopathology 52, 275-283
6. Else K.J., Finkelman F.D., Maliszewski C.R. & Grencis R.K. (1994) Cytokine-mediated regulation of chronic intestinal helminth infection. Journal of Experimental Medicine 179, 347-351
7. Else K.J. & Grencis R.K. (1996) Antibody-independent effector mechanisms in resistance to the intestinal nematode parasite Trichuris muris. Infection and Immunity 64, 2950-2954
8. + T cells abrogates genetic resistance to Haemonchus contortus in sheep. Immunology 78, 43-49
9. Hall G.A., Sopp P. & Howard C.J. (1993) An investigation of temporary workshop clusters reacting with cells of the mononuclcar phagocytic system. Veterinary Immunology and lmmunopathology 39,225-236
10. Hopkins J. (1991) Workshop studies on the ovine CD4 homologue. Veterinary Immunology and Immunopatholony 27, 101-102
11. Jasmer D.P. & McGuire T.C. (1991) Protective immunity to a bloodfeeding nematode (Haemonchus contortus) induced by parasite gut antigens. Infection and Immunity 59, 4412-4417
12. Jasmer D.P., Perryman L.E., Conder G.A., Crow S. & McGuire T. (1993) Protective immunity to Haemonchus contortus induced by immunoaffimty isolated antigens that share a phylogenetically conserved carbohydrate gut surface epitope. Journal of Immunology 151, 5450-5460
13. Jasmer D.P., Perryman L. & McGuire T.C. (1996) Haemonchus contortus GA1 antigens: Related, phospholipasc C-sensitive, apical gut membrane proteins encoded as u polyprotein and released from the nematode during infection. Proceedings of the National Academy of Sciences, USA 93, 8642-8647
14. Katona I.M., Urban J.F., Jr & Finkelman F.D. (1988) The role of L3T4+ and LYT-2+ T cells in the IgE response and immunity to Nippostrongylus brasiliensis. Journal of Immunology 140, 3206-3211
15. Katona I.M., Urban J.F., Jr, Kang S.S., Paul W.E. & Finkelman F.D. (1991) IL-4 requirements for the generation of secondary in vivo IgE responses. Journal of Immunology 146, 4215-4221
16. Keech C.L. & Brandon M.R. (1991) Workshop findings on the ovine homologue of CD5. Veterinary Immunology anil Immumtputhology 27, 103-107
17. + T cells in protective immunity to the murine nematode parasite Trichuris muris. Parasite Immunology 17, 161-165
18. MacHugh N.D. & Sopp P. (1991) Bovine CDS (BoCD8). Veterinary Immunology and Iminunopathology 27,65-69
19. Madden K.B., Urban J.F., Jr., Ziltener H.J., Schrader J.W., Finkelmun F.D. & Katona I.M. (1991) Antibodies to IL-3 and IL-4 suppress helminth-induced intestinal mastocytosis. Journal of Immunology 147,1387-1391
20. Morrison W.I. & Davis W.C. (1991) Differentiation antigens expressed predominantly on CD4- CD8- T lymphocytes (WC1, WC2). Veterinary Immunology and Immunopathology 27, 71 -76
21. Munn E.A., Smith T.S., Graham M, Greenwood C.A., Tavcrnor A.S. & Coetzee G. (1993) Vaccination of merino lambs against haemonchosis with membrane-associated proteins from the adult parasite, Parasitology 106, 63-66
22. NaessensJ.& Howard C.J. (1991) Monoclonal antibodies reacting with bovine cells (BoWC3, BoWC4 und BoWC5). Veterinary Immunology and Immunopathotogy 27, 77-85
23. Naessens J. & Howard C.J. (1993) Summary of workshop findings for cattle. Veterinary Immunology and Immunopathology 39, 25-48
24. Newton S.E. (1995) Progress on vaccination against Haemonchus contortus. International Journal for Parasitology 25, 1281 -1289
25. Newton S.E., Morrish L.E., Martin P.J., Montague P.E. & Rolph T.P, (1995) Protection against multiply drug-resistant and geographically distinct strains of Haemonchus contortus by vaccination with H11, a gut membrane-derived protective antigen. International Journal for Parasitology 25, 511-521
26. Ott R.L. (1993a) The analysis of covariance. In: An Introduction to Statistical Methods and Data Analysis, pp 1020-1038, Duxbury Press, Belmont, CA, USA
27. Ott R.L. (1993b) Introduction to the analysis of variance. In: An Introduction to Statistical Methods and Data Analysis, pp 769- 806, Duxbury Press, Belmont, CA, USA
28. Scott P. (1991) IFN-γ modulates the early development of Th1 and Th2 responses in a murine model of cutaneous leishmaniasis, Journal of Immunology 147, 3149-3155
29. Sher A. & Coffmun R.L. (1992) Regulation of immunity to parasites by T cells and T cell-derived cytokines. Annual Review of Immunology 10, 385-409
30. Shompole S., Perryman L.A., Rurangirwa F.R. et al, (1995) Monoclonal antibody to a conserved epitope on proteins encoded by Babesia bigemina and present on the surface of intact infected erythrocytes. Infection and Immunity 63, 3507-3513
31. Smith W.D. (1993) Protection in lambs immunised with Haemonchus contotus gut membrane proteins. Research in Veterinary Science 54, 94-101
32. Smith W,D. & Smith S.K. (1993) Evaluation of aspects of the protection afforded to sheep immunised with a gut membrane protein of Haemonchus contortus. Research in Veterinary Science 55, 1-9
33. Smith W.D., Smith S.K. & Murray J.M. (1994) Protection studies with integral membrane fractions of Haemonchus contortus. Parasite Immunology 16, 231-241
34. Snedecor G.W. ( 1946) Two variates in two or more groups, covariance. In: Statistical Methods, pp 318-339, Iowa Slate College Press. Ames, IA, USA
35. Soulsby E.J.L. (1965) In: Textbook of Veterinary Clinical Parasitology, vol. I, Helminths, pp 621-704, F.A. Davis company, Philadelphia, PA, USA
36. Svetic A., Madden K.B., di Zhou X. et al. (1993) A primary intestinal helminthic infection rapidly induces a gut-associated elevation of Th2-associated cytokines and IL-3. Journal of Immunology 150, 3434-3441
37. Tavemor A.S., Smith T.S., Langford C.F., Munn E.A. & Graham M. (1992) Vaccination of young Dorset lambs against haemonchosis. Parasite Immunology 14, 645-655
38. + T cells regulate the IgE response and protective immunity in mice, Experimental Parasitology 73, 500511
39. Urban J.F. Jr., Katona I.M., Paul W.E. & Finkelman F.D. (1991) Interleukin 4 is important in protective immunity to a gastrointestinal nematode infection in mice. Proceedings of the National Academy of Sciences, USA 88, 5513-5517
40. Urban J.F. Jr., Madden K.B., Svetic A. et al. (1992) The importance of Th2 cytokines in protective immunity to nematodes. Immunological Reviews 127, 205-220
41. Urban J.F. Jr., Maliszewski C.R., Madden K.B., Katona I.M. & Finkelman F.D. (1995) IL-4 treatment can cure established gastrointestinal nematode infections in immunocompetent and immunedeficient mice. Journal of Immunology 154, 4675-4684