Mutagenicity synergy between paraoxon and mammalian or plant-activated aromatic amines

Environmental and Molecular Mutagenesis

Volumn 30, Issue 3, 1997, Pages 312-320

  Wagner, Elizabeth D ^a   Repetny, Karen ^a   Tan, Jane S ^a   Gichner, Tomáš ^b   Plewa, Michael J ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b INSTITUTE OF EXPERIMENTAL BOTANY   (Czech Republic)

Author keywords

Arylamines; Dielhyl p nitrophenylphosphate; Plant activation; Promutagens; TX1MX

Indexed keywords

AROMATIC AMINE; BENZIDINE; N (2 FLUORENYL)ACETAMIDE; PARAOXON; PHENYLENEDIAMINE; PROMUTAGEN; 3 PHENYLENEDIAMINE; 3-PHENYLENEDIAMINE; MUTAGENIC AGENT; N ACETOXY N (2 FLUORENYL)ACETAMIDE; PHENYLENEDIAMINE DERIVATIVE;

AMES TEST; ARTICLE; DRUG ACTIVATION; DRUG INTERACTION; MUTAGENICITY; PLANT CELL; BIOTRANSFORMATION; DRUG POTENTIATION; GENETICS; MUTAGEN TESTING; PLANT; SALMONELLA TYPHI; TOBACCO;

ACETOXYACETYLAMINOFLUORENE; BIOTRANSFORMATION; DRUG SYNERGISM; MUTAGENICITY TESTS; MUTAGENS; PARAOXON; PHENYLENEDIAMINES; PLANTS, TOXIC; SALMONELLA TYPHI; TOBACCO;

EID: 0030613676     PISSN: 08936692     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2280(1997)30:3<312::AID-EM10>3.0.CO;2-G     Document Type: Article

References (26)

1. Butler AM, Murray M (1993): Inhibition and inactivation of constitutive cytochromes P450 in rat liver by parathion. Mol Pharmacol 43:902-908.
2. Davis JR, Brownson RC, Garcia R (1992): Family pesticide use in the home, garden, orchard and yard. Arch Environ Contam Toxicol 22:260-266.
3. Ecobichon DJ (1991): Toxic effects of pesticides. In Amdur MO, Doull J, Klassen CD (eds): "Cassarett and Doull's Toxicology, 4th ed." New York: Pergamon, pp 565-622.
4. Eling TH, Petry TW, Hughes MF, Krauss RS (1988): Aromatic amine metabolism catalyzed by prostaglandin H synthase. In King CM, Romano LJ, Schuetzle D (eds): "Carcinogenic and Mutagenic Responses to Aromatic Amines and Nitroarenes." New York: Elsevier, pp 161-172.
5. Flessel P, Quintana PJE, Hooper K (1993): Genetic toxicity of Malathion: A review. Environ Mol Mutagen 22:7-17.
6. Gichner T, Stavreva DA, Čeřovská N, Wagner ED, Plewa MJ (1995): Metabolic activation of m-phenylenediamine to products mutagenic in Salmonella typhimurium by medium isolated from tobacco suspension cell cultures. Mutat Res 331:127-132.
7. Gichner T, Velemínský J, Wagner ED, Plewa MJ (1996): Mutagenic synergy between paraoxon and plant-activated m-phenylenediamine or 2-acetoxyacetylaminofluorene. Environ Mol Mutagen 27:59-66.
8. Glatt H, Oesch F (1985): Activation of N-acetoxy-and N-hydroxy-2-acetylaminofluorene to mutagenic and cytotoxic metabolites by V79 Chinese hamster cells. Mutat Res 149:265-269.
9. Hatcher JF, Rao KP, Swaminathan S (1993): Mutagenic activation of 4-aminobiphenyl and its N-hydroxy derivatives by microsomes from cultured human uroepithelial cells. Mutagenesis 8:113-120.
10. Heflich RH, Djuric Z, Zhuo Z, Fullerton NF, Casciano DA, Beland FA (1988): Metabolism of 2-acetylaminofluorene in Chinese hamster ovary cell mutation assay. Environ Mol Mutagen 11:167-181.
11. Hongslo J, Haug LT, Wirth PJ, Moller M, Dybing E, Thorgeirsson SS (1983): Influence of conjugation reactions on the mutagenicity of aromatic amines. Mutat Res 107:239-247.
12. Irving CC (1966): Enzymatic deacetylation of N-hydroxy-2-acetylaminofluorene by liver microsomes. Cancer Res 26:1390-1396.
13. Ju YH, Plewa MJ (1997a): The plant-activation of the bicyclic aromatic amines benzidine and 4-aminobiphenyl. Environ Mol Mutagen 29:81-90.
14. Ju YH, Plewa MJ (1997b): Involvement of nitroreductase and O-acetyltransferase on the mutagenicity of plant-activated benzidine and 4-aminobipheyl. Environ Mol Mutagen 30:330-338.
15. Kutz FW, Cook BT, Carter-Pokras OD, Brody D, Murphy RS (1992): Selected pesticide residues and metabolites in urine from a survey of the U.S. general population. J Toxicol Environ Health 37:277-291.
16. Maron DM, Ames BN (1983): Revised methods for the Salmonella mutagenicity test. Mutat Res 113:173-215.
17. Mississippi State Department of Health (1996): "Agricultural Pesticide Emergency-December 27, 1996." http://www.msdh.state.m-s.us:80/breaknew.htm
18. Nakatsugawa T (1992): Hepatic disposition of organophosphorus insecticides: A synthesis of in vitro, in situ and in vivo data. In Chambers JE, Levi PE (eds): "Organophosphates: Chemistry, Fate and Effects." San Diego, CA: Academic Press, pp 201-227.
19. Plewa MJ, Gichner T, Xin H, Seo K-Y, Smith SR, Wagner ED (1993): Biochemical and mutagenic characterization of plant-activated aromatic amines. Environ Toxicol Chem 12:1353-1363.
20. Plewa MJ, Wagner ED, Stavreva DA, Gichner T (1995): Plant activation and its role in environmental mutagenesis and antimutagenesis. Mutat Res 350:163-171.
21. Plewa MJ, Wagner ED, Yu TW, Anderson D (1997): Paraoxon-mediated antimutagenicity and mutagenic synergy of dietary arylamines assayed in Salmonella typhimurium and human lymphocytes. J Environ Pathol Toxicol Oncol (in press).
22. Rodriguez-Ariza A, Diaz-Mendez FM, Navas JI, Pueyo C, Lopez-Barea J (1995): Metabolic activation of carcinogenic aromatic amines by fish exposed to environmental pollutants. Environ Mol Mutagen 25:50-57.
23. Seo K-Y, Riley J, Cortez D, Wagner ED, Plewa MJ (1993): Characterization of stable high molecular weight mutagenic product(s) of plant-activated m-phenylenediamine. Mutat Res 299:111-120.
24. Smith BJ, DeBruin L, Josephy PD, Eling TE (1992): Mutagenic activation of benzidine requires prior bacterial acetylation and subsequent conversion by prostaglandin H synthase to 4-nitro-4′-(acetylamino)biphenyl. Chem Res Toxicol 5:431-439.
25. Venkat JA, Shami S, Davis K, Nayak M, Plimmer JR, Pfeil R, Nair PP (1995): Relative genotoxic activities of pesticides evaluated by a modified SOS microplate assay. Environ Mol Mutagen 25:67-76.
26. Wagner ED, Smith SR, Xin H, Plewa MJ (1994): Comparative mutagenicity of plant-activated aromatic amines using Salmonella strains with different acetyltransferase activities. Environ Mol Mutagen 23:64-69.