A(2A) adenosine receptors inhibit ATP-induced Ca2+ influx in PC12 cells by involving protein kinase A

Journal of Neurochemistry

Volumn 68, Issue 5, 1997, Pages 2177-2185

  Park, Tae Ju ^a   Song, Sook Keun ^a   Kim, Kyong Tai ^a  

^a Pohang University of Science and Technology (POSTECH)   (South Korea)

Author keywords

ATP; ATP gated cation channels; CGS 2168O; PC12 cells; Protein kinase A

Indexed keywords

ADENOSINE A2A RECEPTOR; ADENOSINE TRIPHOSPHATE; CALCIUM ION; CYCLIC AMP DEPENDENT PROTEIN KINASE; 2 [4 (2 CARBOXYETHYL)PHENETHYLAMINO]ADENOSINE 5' (N ETHYLCARBOXAMIDE); ADENOSINE; ADENOSINE RECEPTOR; CALCIUM; CALCIUM CHANNEL; CATION; DRUG DERIVATIVE; INOSITOL 1,4,5 TRISPHOSPHATE; ION CHANNEL; PHENETHYLAMINE DERIVATIVE; PROTEIN KINASE C; PURINE RECEPTOR;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM MOBILIZATION; CELL MEMBRANE PERMEABILITY; CHANNEL GATING; CONTROLLED STUDY; NONHUMAN; PHEOCHROMOCYTOMA CELL; PRIORITY JOURNAL; RAT; ANIMAL; BIOSYNTHESIS; CELL STRAIN; DRUG EFFECT; DRUG POTENTIATION; ELECTROPHYSIOLOGY; INTRACELLULAR MEMBRANE; METABOLISM; OSMOLARITY; PHYSIOLOGY;

ANIMALIA;

ADENOSINE; ADENOSINE TRIPHOSPHATE; ANIMALS; CALCIUM; CALCIUM CHANNELS; CATIONS; CYCLIC AMP-DEPENDENT PROTEIN KINASES; ELECTROPHYSIOLOGY; INOSITOL 1,4,5-TRISPHOSPHATE; INTRACELLULAR MEMBRANES; ION CHANNEL GATING; ION CHANNELS; OSMOLAR CONCENTRATION; PC12 CELLS; PHENETHYLAMINES; PROTEIN KINASE C; RATS; RECEPTORS, PURINERGIC; RECEPTORS, PURINERGIC P1;

EID: 0030612686     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1997.68052177.x     Document Type: Article

References (44)

1. Bean B. P. (1992) Pharmacology and electrophysiology of ATP-activated ion channels. Trends Pharmacol. Sci. 13, 87-90.
2. Brake A. J., Wagenbach M. J., and Julius D. (1994) New structural motif for ligand-gated ion channels defined by an ionotropic ATP receptor. Nature 371, 519-523.
3. Burnstock G. (1978) A basis for distinguishing two types of purinergic receptor, in Cell Membrane Receptors for Drugs and Hormones: A Multidisciplinary Approach (Bolis L. and Straub R. W., eds), pp. 107-118. Raven Press, New York.
4. 3H]inositol 1,4,5-triphosphate binding sites in adrenal-cortical membranes. Biochem. J. 265, 421-427.
5. Charest R., Blackmore P. F., and Exton J. H. (1985) Characterization of responses of isolated rat hepatocytes to ATP and ADP. J. Biol. Chem. 260, 15789-15794.
6. Clapham D. E. (1996) TRP is cracked but is CRAC TRP? Neuron 16, 1069-1072.
7. 2+ influx is regulated via a pertussis toxin-sensitive mechanism in a PC12 cell clone. Biochem. Biophys. Res. Commun. 188, 1184-1190.
8. Collis M. and Hourani M. O. (1993) Adenosine receptor subtypes. Trends Pharmacol. Sci. 14, 360-366.
9. Daly J. W. (1982) Adenosine receptors: targets for future drugs. J. Med. Chem. 25, 197-207.
10. Di Virgilio F., Fasolato C., and Steinberg T. H. (1988) Inhibitors of membrane transport system for organic anions block fura-2 excretion from PC12 and N2A cells. Biochem. J. 256, 959-963.
11. 2-purinergic receptors for extracellular ATP. Am. J. Respir. Cell Mol. Biol. 4, 295-300.
12. El-Moatassim C., Dornand J., and Mani J.-C. (1992) Extracellular ATP and cell signalling. Biochim. Biophys. Acta 1134, 31-45.
13. Fasolato C., Pizzo P., and Pozzan T. (1990) Receptor-mediated calcium influx in PC12 cells. J. Biol. Chem. 265, 20351-20355.
14. 2+ indicators with greatly improved fluorescence properties. J. Biol. Chem. 260, 3440-3450.
15. 2A adenosine receptors from rat striatum and rat pheochromocytoma PC12 cells: characterization with radioligand binding and by activation of adenylyl cyclase. Mol. Pharmacol. 41, 352-359.
16. Inoue K., Nakazawa K., Fujimori K., and Takanaka A. (1989) Extracellular adenosine 5′-triphosphate-evoked norepinephrine secretion not relating to voltage-gated Ca channels in pheochromocytoma PC12 cells. Neurosci. Lett. 106, 294-299.
17. Inoue K., Nakazawa K., Ohara-Imaizumi M., Obama T., Fujimori K., and Takanaka A. (1991) Antagonism by reactive blue 2 but not by brillant blue G of extracellular ATP-evoked responses in PC12 phaeochromocytoma cells. Br. J. Pharmacol. 102, 851-854.
18. Inoue K., Watano T., Koizumi S., Nakazawa K., and Burnstock G. (1994) Dual modulation of adenosine of ATP-activated channels through GTP-binding proteins in rat pheochromocytoma PC12 cells. Eur. J. Pharmacol 268, 223-229.
19. 2a-adenosine receptors: stability and antagonist binding. Arch. Biochem. Biophys. 305, 611-617.
20. 2a adenosine receptor. J. Biol. Chem. 270, 13987-13997.
21. 2 receptors in PC12 cells. J. Biol. Chem. 269, 6471-6477.
22. 2+ influx and phosphoinositide hydrolysis by extracellular adenosine triphosphate in rat PC12 pheochromocytoma cells. Endocrinology 133, 166-170.
23. Kuroki M., Takeshige K., and Minakami S. (1989) ATP-induced calcium mobilization in human neutrophils. Biochim. Biophys. Acta 1012, 103-106.
24. Majid M. A., Okajima F., and Kondo Y. (1992) Characterization of ATP receptor which mediates norepinephrine release in PC12 cells. Biochim. Biophys. Acta 1136, 283-289.
25. 2+ system through a receptor different from the 53-kDa ATP receptor in PC12 cells. Biochem. Biophys. Res. Commun. 195, 415-421.
26. Murrin R. J. A. and Boarder M. R. (1992) Neuronal "nucleotide" receptor linked to phospholipase C and phospholipase D? Stimulation of PC12 cells by ATP analogues and UTP. Mol. Pharmacol. 41, 561-568.
27. Nakazawa K., Fujimori K., Takanaka A., and Inoue K. (1990) An ATP-activated conductance in pheochromocytoma cells and its suppression by extracellular calcium. J. Physiol. (Lond.) 428, 257-272.
28. 2 receptor antagonist, to rat brain membranes Mol. Pharmacol. 46, 817-822.
29. 2 receptor in PC12 cells. Life Sci. 39, 1059-1067.
30. Park T.-J. and Kim K.-T. (1996) Cyclic AMP-independent inhibition of voltage-sensitive calcium channels by forskolin in PC12 cells. J. Neurochem. 66, 83-88.
31. 2+ and cyclic AMP in addition to inhibiting protein kinase C in rat islets of Langerhans. Mol. Cell. Endocrinol. 94, 55-60.
32. Putney J. W. Jr. and Bird G. St. J. (1993) The signal for capacitative calcium entry. Cell 75, 199-201.
33. Reber B. F. X., Neuhaus R., and Reuter H. (1992) Activation of different pathways for calcium elevation by bradykinin and ATP in rat pheochromocytoma (PC12) cells. Pflugers Arch. 420, 213-218.
34. Rhoads A. R., Parui R., Vu N.-D., Cadogan R., and Wagner P. D. (1993) ATP-induced secretion in PC12 cells and photoaffinity labeling of receptors. J. Neurochem. 61, 1657-1666.
35. Rothermel J. D., Jastorff B., and Parker Botelho L. H. (1984) Inhibition of glucagon-induced glycogenolysis in isolated rat hepatocytes by the Rp diastereomer of adenosine cyclic 3′,5′-phosphorothioate. J. Biol. Chem. 259, 8151-8155.
36. Sela D., Ram E., and Atlas D. (1991) ATP receptor. J. Biol. Chem. 266, 17990-17994.
37. Spielman W. S. and Arend L. J. (1991) Adenosine receptors and signaling in the kidney. Hypertension 17, 117-130.
38. 2+ channels in PC12 cells. Biochem. Pharmacol. 47, 1262-1266.
39. Suh B.-C. and Kim K.-T. (1995) Identification of the M3 muscarinic receptor which is coupled to phospholipase C and adenylyl cyclase in SK-N-BE(2)C cells. Mol. Cells 5, 86-92.
40. Suh B.-C., Lee C.-O., and Kim K.-T. (1995) Signal flows from two phospholipase C-linked receptors are independent in PC12 cells. J. Neurochem. 64, 1071-1079.
41. 2+ responses: role of protein kinases. Biochem. J. 295, 255-261.
42. 2+-ATPase. Proc. Natl. Acad. Sci. USA 87, 2466-2470.
43. van Haastert P. J. M., Van Driel R., Jastorff B., Baraniak J., Stec W. J., and De Wit R. J. W. (1984) Competitive cAMP antagonists for cAMP-receptor proteins. J. Biol. Chem. 259, 10020-10024.
44. 2+ influx by heterotrimeric G proteins. J. Biol. Chem. 270, 29169-29175.