Crosstalk during Ca2+-, cAMP-, and glucocorticoid-induced gene expression in lymphocytes

Molecular and Cellular Endocrinology

Volumn 128, Issue 1-2, 1997, Pages 29-37

  Dowd, Diane R ^a   Ryerse, Jan S ^a   MacDonald, Paul N ^a   Miesfeld, Roger L ^b   Kamradt, Merideth C ^a  

^a S LOUIS UNIV HLTH SCIENCES CENTER   (United States)

^b University of Arizona   (United States)

Author keywords

Apoptosis; Ca2+; cAMP; Cyclic AMP response element binding protein; Glucocorticoids

Indexed keywords

CALCIMYCIN; CALCIUM ION; CYCLIC AMP; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; DEXAMETHASONE; FORSKOLIN; GLUCOCORTICOID; THAPSIGARGIN; CALCIUM; CHLORAMPHENICOL ACETYLTRANSFERASE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL LINE; CELL VIABILITY; GENE EXPRESSION; LYMPHOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; THYMOMA; ANIMAL; BIOSYNTHESIS; CELL CULTURE; CELL DIVISION; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; METABOLISM; PHYSIOLOGY; REPORTER GENE; SIGNAL TRANSDUCTION; ULTRASTRUCTURE;

ANIMALS; APOPTOSIS; CALCIMYCIN; CALCIUM; CELL DIVISION; CHLORAMPHENICOL O-ACETYLTRANSFERASE; CYCLIC AMP; DEXAMETHASONE; FORSKOLIN; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, REPORTER; GLUCOCORTICOIDS; LYMPHOCYTES; MICE; SIGNAL TRANSDUCTION; THAPSIGARGIN; THYMOMA; THYMUS NEOPLASMS; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0030612221     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0303-7207(96)04012-9     Document Type: Article

References (48)

1. Lam, M., Dubyak, G. and Distelhorst, C.W. (1993) Effect of glucocorticosteroid treatment on intracellular calcium homeostasis in mouse lymphoma cells. Mol. Endocrinol. 7, 686-693.
2. 2+ fluxes. Proc. Natl. Acad. Sci. USA 9, 6569-6573.
3. Wyllie, A.H., Kerr, J.F.R and Currie, A.R. (1980) Cell death: the significance of apoptosis. Int. Rev. Cytol. 68, 251-306.
4. 2+ regulation of apoptosis. In: Advances in Second Messenger and Phosphoprotein Research (Means, A.R., ed.), pp. 255-280, Raven Press, New York.
5. 2+ in cell injury, necrosis and apoptosis. Curr. Biol. 4, 227-232.
6. Nicotera, P., Zhivotovsky, B. and Orrenius, S. (1994) Nuclear calcium transport and the role of calcium in apoptosis. Cell Calcium 16, 279-288.
7. 2+ concentration. Arch. Biochem. Biophys. 269, 365-370.
8. Lytton, J., Westlin, M. and Hanley, M.R. (1991) Thapsigargin inhibits the sarcoplasmic or endoplasmic reticulum Ca-ATPase family of calcium pumps. J. Biol. Chem. 266, 17067-17071.
9. 2+-ATPase. Proc. Natl. Acad. Sci. USA 87, 2466-2470.
10. Dowd, D.R, MacDonald, P.N., Komm, B.S., Haussler, M.R and Miesfeld, R (1991) Evidence for early induction of calmodulin gene expression in lymphocytes undergoing glucocorticoid-mediated apoptosis. J. Biol. Chem. 266, 18423-18426.
11. Baughman, G., Harrigan, M.T., Campbell, N.F., Nurrish, S.J. and Bourgeois, S. (1991) Genes newly identified as regulated by glucocorticoids in murine thymocytes. Mol. Endocrinol. 5, 637-644.
12. 28K cDNA interferes with the apoptotic pathway in lymphocytes. Mol. Endocrinol. 6, 1843-1848.
13. 2+ in toxic cell killing. TiPS 10, 281-285.
14. Farber, J.L. (1990) The role of calcium ions in toxic cell injury. Environ. Health Perspect. 84, 107-111.
15. Wyllie, A.H., Morris, R.G., Smith, A.L. and Dunlop, D. (1984) Chromatin cleavage in apoptosis: association with condensed chromatin morphology and dependence on macromolecular synthesis. J. Pathol. 142, 67-77.
16. Resendez, E., Jr., Attenello, J.W., Grafsky, A., Chang, C.S. and Lee, A.S. (1985) Calcium ionophore A23187 induces expression of glucose-regulated genes and their heterologous fusion genes. Mol. Cell. Biol. 5, 1212-1219.
17. Rodland, K.D., Pribnow, D., Lenormand, P., Li-Ye Chen, S. and Mahun, B.E. (1993) Characterization of a unique enhancer element responsive to cyclic adenosine 3′,5′-monophosphate and elevated calcium. Mol. Endocrinol. 7, 787-796.
18. Sheng, M., McFadden, G. and Greenberg, M.E. (1990) Membrane depolorization and calcium induce c-fos transcription via phosphorylation of transcription factor CREB. Neuron 4, 571-582.
19. 2+ -ATPase, enhances c-fos expression but antogonizes vacuole formation of human hepatoma cells induced by teleocidin. Biochim. Biophys. Acta 1177, 31-36.
20. 2+ -ATPase inhibitor thapsigargin. Proc. Natl. Acad. Sci. USA 88, 7096-7100.
21. 2+/calmodulin- as well as cAMP-dependent protein kinase. Proc. Natl. Acad. Sci. USA 88, 5061-5065.
22. 2+-regulated transcription factor phosphorylated by calmodulin-dependent kinases. Science 252, 1427-1430.
23. Steger, D.J., Altschmied, J., Buscher, M. and Mellon, P.L. (1991) Evolution of placenta-specific gene expression: comparison of the equine and human gonadotropin α-subunit genes. Mol. Endocrinol. 5, 243-255.
24. Delegeane, A.M., Ferland, L.H. and Mellon, P.L. (1987) Tissue-specific enhancer of the human glycoprotein hormone α-subunit gene: Dependence on cyclic AMPinducible elements. Mol. Cell. Biol. 7, 3994-4002.
25. Silver, B.J., Bokar, J.A., Virgin, J.B., Vallen, E.A., Milsted, A. and Nilson, J.H. (1987) Cyclic AMP regulation of the human glycoprotien hormone α-subunit gene is mediated by an 18-base-pair element. Proc. Natl. Acad. Sci. USA 84, 2198-2202.
26. Rouet, P., Raguenez, G. and Salier, J.-P. (1992) Optimized assays for quantifying transient expressions of co-transfected β-galactosidase and CAT reporter genes. Biotechniques 13, 700-701.
27. Ginty, D.D., Kornhauser, J.M., Thompson, M.A., Bading, H., Mayo, KE., Takahashi, J.S. and Greenberg, M.E. (1993) Regulation of CREB phosphorylation in the suprachiasmatic nucleus by light and a circadian clock. Science 260, 238-241.
28. 2+-ATPase inhibitor thapsigargin. Exp. Cell Res. 212, 84-92.
29. Collins, R.J., Harmon, B.V., Gobe, G.C. and Kerr, J.F.R. (1992) Internucleosomal DNA cleavage should not be the sole criterion for identifying apoptosis. Int. J. Radiat. Biol. 61, 451-453.
30. Dowd, D.R and Miesfeld, R.L. (1992) Evidence that glucocorticoid- and cyclic AMP-induced apoptotic pathways in lymphocytes share distal events. Mol. Cell. Biol. 12, 3600-3608.
31. Kaiser, N. and Edelman, I.S. (1978) Further studies on the role of calcium in glucocorticoid-induced lymphocytolysis. Endocrinology 103, 936-942.
32. Caron-Leslie, L.-A.M. and Cidlowski, J.A. (1991) Similar actions of glucocorticoids and calcium on the regulation of apoptosis in S49 cells. Mol. Endocrinol. 5, 1169-1179.
33. Seamon, K.B., Padgett, W. and Daly, J.W. (1981) Forskolin: unique diterpene activator of adenylate cyclase in membranes and in intact cells. Proc. Natl. Acad. Sci. USA 78, 3363-3367.
34. Sheng, M., Dougan, S.T., McFadden, G. and Greenberg, M.E. (1988) Calcium and growth factor pathways of c-fos transcriptional activation require distinct upstream regulatory sequences. Mol. Cell. Biol. 8, 2787-2796.
35. Gruol, D.J., Rajah, F.M. and Bourgeois, S. (1989) Cyclic AMP-dependent protein kinase modulation of the glucocorticoid-induced cytolytic response in murine T-lymphoma cells. Mol. Endocrinol. 3, 2119-2127.
36. Gonzalez, G.A. and Montminy, M.R (1989) Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133. Cell 59, 675-680.
37. Matthews, R.P., Guthrie, C.R., Wailes, L.M., Zhao, X., Means, A. and McKnight, G.S. (1994) Calcium/calmodulin-dependent protein kinase types II and IV differentially regulate CREB-dependent gene expression. Mol. Cell. Biol. 14, 6107-6116.
38. 2+/calmodulin-dependent protein kinases type I, II, and IV. J. Biol. Chem. 271, 3066-3073.
39. Kaiser, N. and Edelman, I.S. (1977) Calcium dependence of glucocorticoid-induced lymphocytolysis. Proc. Natl. Acad. Sci. USA 1974, 638-642.
40. 2+/calmodulin-dependent protein kinase type II and type IV involves phosphorylation of a site that negatively regulates activity. Genes Dev. 8, 2527-2539.
41. 2+-calmodulin-dependent protein kinase type Gr in rat cerebellar cortex. Proc. Natl. Acad. Sci. USA 88, 2850-2853.
42. Cruzalegui, F.H. and Means, A.R. (1993) Biochemical characterization of the multifunctional calcium/calmodulin-dependent protein kinase type IV expressed in insect cells. J. Biol. Chem. 268, 26171-26178.
43. 2+/ calmodulin kinase types II and IV regulate c-fos transcription in the AtT20 corticotroph cell line. Mol. Cell. Endocrinol. 120, 1-8.
44. Yamamoto, K.K., Gonzalez, G.A., Biggs, W.H., III and Montminy, M.R. (1988) Phosphorylation induced binding and transcriptional efficacy of nuclear factor CREB. Nature 334, 494-498.
45. Gruol, D.J., Campbell, N.F. and Bourgeois, S. (1986) Cyclic AMP-dependent protein kinase promotes glucocorticoid receptor function. J. Biol. Chem. 261, 4909-4914.
46. Gruol, D.J. and Altschmied, J. (1993) Synergistic induction of apoptosis with glucocorticoids and 3′,5′-cyclic adenosine monophosphate reveals agonist activity by RU 486. Mol. Endocrinol. 7, 104-113.
47. Rangarajan, P.N., Umesono, K. and Evans, R.M. (1992) Modulation of glucocorticoid receptor function by protein kinase A. Mol. Endocrinol. 6, 1451-1457.
48. Flomerfelt, F.A. and Miesfeld, R.L. (1994) Recessive mutations in a common pathway block thymocyte apoptosis induced by multiple signals. J. Cell Biol. 127, 1729-1742.