Models of Alzheimer's disease: Cellular and molecular aspects

Journal of Neural Transmission, Supplement

Volumn , Issue 49, 1997, Pages 11-21

  Hoyer, S ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; INSULIN; ADENOSINE TRIPHOSPHATE; INSULIN RECEPTOR;

AGING; ALZHEIMER DISEASE; BRAIN METABOLISM; DEGENERATIVE DISEASE; ENERGY METABOLISM; GLUCOSE METABOLISM; HUMAN; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; REVIEW; ANIMAL; BIOLOGICAL MODEL; BRAIN; METABOLISM; NERVE CELL; PHYSIOLOGY; STRESS;

ADENOSINE TRIPHOSPHATE; AGING; ALZHEIMER DISEASE; ANIMALS; BRAIN; ENERGY METABOLISM; GLUCOSE; HUMANS; MODELS, NEUROLOGICAL; NEURONS; RECEPTOR, INSULIN; STRESS;

EID: 0030612192     PISSN: 03036995     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-3-7091-6844-8_2     Document Type: Review

References (22)

1. Bak P, Tang C, Wiesenfeld K (1988) Self-organized criticality. Phys Rev A 38: 364-374
2. Benzi G, Pastoris O, Villa RF, Giuffrida AM (1984) Effect of aging on cerebral cortex energy metabolism in hypoglycemia and posthypoglycemic recovery. Neurobiol Aging 5: 205-212
3. Braakman I, Helenius J, Helenius A (1992) Role of ATP and disulphide bonds during protein folding in the endoplasmic reticulum. Nature 356: 260-262
4. Bucht G, Adolfsson R, Lithner F, Winblad B (1993) Changes in blood glucose and insulin secretion in patients with senile dementia of Alzheimer type. Acta Med Scand 213: 387-392
5. Burnstock G (1990) Purinergic mechanisms. Ann NY Acad Sci 603: 1-17
6. Buttgereit F, Brand MD (1995) A hierarchy of ATP-consuming processes in mammalian cells. Biochem J 312: 163-167
7. Castro M, Pedrosa D, Osuma JI (1993) Impaired insulin release in aging rats: metabolic and ionic events. Experientia 49: 850-853
8. Chiang HL, Terlecky SR, Plant CP, Dice JF (1989) A role for a 70-kilodalton heat shock protein in lysosomal degradation of intracellular proteins. Science 246: 382-385
9. Dastur DK (1985) Cerebral blood flow and metabolism in normal human aging, pathological aging, and senile dementia. J Cereb Blood Flow Metab 5: 1-9
10. Dastur DK, Lane MH, Hansen DB, Kety SS, Butler RN, Perlin S, Sokoloff L (1963) Effects of aging on cerebral circulation and metabolism in man. In: Birren JE, Butler RN, Greenhouse S, Sokoloff L, Yarrow MR (eds) Human aging - a biological and behavioural study. U.S. Department of Health, Education and Welfare, National Institute of Mental Health, Bethesda (DHEW Publication No 986)
11. Dutschke K, Nitsch RM, Hoyer S (1994) Short-term mental activation accelerates the age-related decline in brain tissue levels of high energy phosphates. Arch Gerontol Geriatr 19: 43-51
12. Edwards FA, Gibb AJ, Colquhoun D (1992) ATP receptor-mediated synaptic currents in the central nervous system. Nature 359: 144-147
13. Ehrlich YH, Davis TB, Bocke E, Kornecki E, Lenox RH (1986) Ectoprotein kinase activity on the external surface of neural cells. Nature 302: 67-70
14. Erecinska M, Silver IA (1989) ATP and brain function. J Cereb Blood Flow Metab 9: 2-19
15. Evans DA, Funkenstein HH, Albert MS, Scherr PA, Cook NR, Chown MJ, Hebert LE, Hennekens CH, Taylor JO (1989) Prevalence of Alzheimer's disease in a community population of older persons: higher than previously reported. J Am Med Assoc 262: 2551-2556
16. Farrer LA, Myers RA, Cupples LA, St. George-Hyslop PH, Bird TD, Rossor MN, Mullan MJ, Polinsky R, Nee L, Heston L, van Broeckhoven C, Martin JJ, Crapper McLachlan D, Growdon JH (1990) Transmission and age-at-onset patterns in familial Alzheimer's disease: evidence for heterogeneity. Neurology 40: 395-403
17. Frackowiak RS, Pozzilli C, Legg NJ, DuBoulay GH, Marshall J, Lenzi GL, Jones T (1981) Regional cerebral oxygen supply and utilization in dementia. A clinical and physiological study with oxygen-15 and positron tomography. Brain 104: 743-778
18. Fujisawa Y, Sasaki K, Akiyama K (1991) Increased insulin levels after OGTT load in peripheral blood and cerebrospinal fluid of patients with dementia of Alzheimer type. Biol Psychiatry 30: 1219-1228
19. Gething MJ, Sambrook J (1992) Protein folding in the cell. Nature 355: 33-45
20. Gibson GE, Blass JP (1976) Impaired synthesis of acetylcholine in brain accompanying mild hypoxia and hypoglycemia. J Neurochem 27: 37-42
21. Gibson GE, Peterson C (1981) Aging decreases oxidative metabolism and the release and synthesis of acetylcholine. J Neurochem 37: 978-984
22. Gibson GE, Jope R, Blass JP (1975) Decreased synthesis of acetylcholine accompanying impaired oxidation of pyruvic acid in rat brain minces. Biochem J 148: 17-23